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Select item 106848911.

INPP5D regulates inflammasome activation in human microglia

Vicky Chou, Richard V. Pearse, II, Aimee J. Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B. Fancher, Alina Sigalov, Courtney R. Benoit, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Philip L. De Jager, Vilas Menon, Tracy L. Young-Pearse

Nat Commun. 2023; 14: 7552. Published online 2023 Nov 29. doi: 10.1038/s41467-023-42819-w

PMCID:: PMC10684891

Abstract Article PDF–5.2M

Select item 106065682.

INPP5D/SHIP1: Expression, Regulation and Roles in Alzheimer’s Disease Pathophysiology

Edward O. Olufunmilayo, R. M. Damian Holsinger

Genes (Basel) 2023 Oct; 14(10): 1845. Published online 2023 Sep 23. doi: 10.3390/genes14101845

PMCID:: PMC10606568

Abstract Article PDF–1.0M

Select item 100482523.

Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer’s Disease Neuropathology and Genetics

Diana J. Zajac, James Simpson, Eric Zhang, Ishita Parikh, Steven Estus

Genes (Basel) 2023 Mar; 14(3): 763. Published online 2023 Mar 21. doi: 10.3390/genes14030763

PMCID:: PMC10048252

Abstract Article PDF–3.7M

Select item 99860544.

Multistep IgE Mast Cell Desensitization Is a Dose- and Time-Dependent Process Partially Regulated by SHIP-1

Ather Adnan, Shree Acharya, Leila A. Alenazy, Leticia de las Vecillas, Pedro Giavina Bianchi, Matthieu Picard, Lucia Calbache-Gil, Salvador Romero-Pinedo, Ana Clara Abadí´a-Molina, William Kerr, Chiara Pedicone, Jun Nagai, Eleanor Hollers, Daniel Dwyer, Mariana Castells

J Immunol. 2023 Mar 15; 210(6): 709–720. Published online 2023 Mar 15. doi: 10.4049/jimmunol.2100485

PMCID:: PMC9986054

Abstract Article PDF–2.3M

Select item 67322525.

Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene

Xiaohui Yao, Shannon L. Risacher, Kwangsik Nho, Andrew J. Saykin, Ze Wang, Li Shen

Neurobiol Aging. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Neurobiol Aging. 2019 Sep; 81: 213–221. Published online 2019 Jun 18. doi: 10.1016/j.neurobiolaging.2019.06.003

PMCID:: PMC6732252

Abstract Article PDF–1.4M

Select item 55405896.

Analysis of SHIP1 expression and activity in Crohn’s disease patients

Rajesh Somasundaram, Sandra Fernandes, Jasper J. Deuring, Colin de Haar, Ernst J. Kuipers, Lauran Vogelaar, Frank A. Middleton, C. Janneke van der Woude, Maikel P. Peppelenbosch, William G. Kerr, Gwenny M. Fuhler

PLoS One. 2017; 12(8): e0182308. Published online 2017 Aug 2. doi: 10.1371/journal.pone.0182308

PMCID:: PMC5540589

Abstract Article PDF–2.5M

Select item 53424727.

INPP5D rs35349669 polymorphism with late-onset Alzheimer's disease: A replication study and meta-analysis

Hua Jing, Jun-Xia Zhu, Hui-Fu Wang, Wei Zhang, Zhan-Jie Zheng, Ling-Li Kong, Chen-Chen Tan, Zi-Xuan Wang, Lin Tan, Lan Tan

Oncotarget. 2016 Oct 25; 7(43): 69225–69230. Published online 2016 Oct 13. doi: 10.18632/oncotarget.12648

PMCID:: PMC5342472

Abstract Article PDF–794K

Select item 49912158.

Discovery and Development of Small Molecule SHIP Phosphatase Modulators

Dennis R. Viernes, Lydia B. Choi, William G. Kerr, John D. Chisholm

Med Res Rev. Author manuscript; available in PMC 2016 Aug 19.

Published in final edited form as: Med Res Rev. 2014 Jul; 34(4): 795–824. Published online 2013 Dec 2. doi: 10.1002/med.21305

PMCID:: PMC4991215

Abstract Article PDF–1.6M

Select item 48261619.

SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice

Melisa J. Hamilton, Elizabeth C. Halvorsen, Nancy E. LePard, Momir Bosiljcic, Victor W. Ho, Vivian Lam, Judit Banáth, Kevin L. Bennewith, Gerald Krystal

Oncotarget. 2016 Jan 26; 7(4): 3677–3691. Published online 2015 Dec 14. doi: 10.18632/oncotarget.6611

PMCID:: PMC4826161

Abstract Article PDF–7.6M

Select item 451535310.

Inhibitor and activator: dual functions for SHIP in immunity and cancer

William G. Kerr

Ann N Y Acad Sci. Author manuscript; available in PMC 2015 Jul 26.

Published in final edited form as: Ann N Y Acad Sci. 2011 Jan; 1217: 1–17. Published online 2010 Dec 13. doi: 10.1111/j.1749-6632.2010.05869.x

PMCID:: PMC4515353

Abstract Article PDF–450K

Select item 273587911.

Inactivation of SHIP1 in T- cell Acute Lymphoblastic Leukemia due to Mutation and Extensive Alternative Splicing

Tony C. T. Lo, Lisa M. Barnhill, Youngjin Kim, Elizabeth Ann Nakae, Alice L. Yu, Mitchell B. Diccianni

Leuk Res. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Leuk Res. 2009 Nov; 33(11): 1562–1566. Published online 2009 May 26. doi: 10.1016/j.leukres.2009.04.032

PMCID:: PMC2735879

Abstract Article PDF–545K

Select item 136032712.

Upregulation of Immunoregulatory Src Homology 2 Molecule Containing Inositol Phosphatase and Mononuclear Cell Hyporesponsiveness in Oral Mucosa during Chronic Periodontitis

Manoj Muthukuru, Christopher W. Cutler

Infect Immun. 2006 Feb; 74(2): 1431–1435. doi: 10.1128/IAI.74.2.1431-1435.2006

PMCID:: PMC1360327

Abstract Article PDF–202K

Select item 1000892713.

CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression

Dianyin Yang, Dongyang Zhao, Jinlu Ji, Chunxue Wang, Na Liu, Xiaowei Bao, Xiandong Liu, Sen Jiang, Qianqian Zhang, Lunxian Tang

Front Immunol. 2023; 14: 1095457. Published online 2023 Feb 27. doi: 10.3389/fimmu.2023.1095457

PMCID:: PMC10008927

Abstract Article PDF–6.0M

Select item 808251514.

INPP5D expression is associated with risk for Alzheimer’s disease and induced by plaque-associated microglia

Andy P. Tsai, Lin Peter Bor-Chian, Chuanpeng Dong, Miguel Moutinho, Brad T. Casali, Yunlong Liu, Bruce T. Lamb, Gary E. Landreth, Adrian L. Oblak, Kwangsik Nho

Neurobiol Dis. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Neurobiol Dis. 2021 Jun; 153: 105303. Published online 2021 Feb 22. doi: 10.1016/j.nbd.2021.105303

PMCID:: PMC8082515

Abstract Article PDF–1.5M

Select item 597231015.

SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn’s Disease and Peripheral T Cell Reduction

Sandra Fernandes, Neetu Srivastava, Raki Sudan, Frank A. Middleton, Amandeep K. Shergill, James C. Ryan, William G. Kerr

Front Immunol. 2018; 9: 1100. Published online 2018 May 22. doi: 10.3389/fimmu.2018.01100

PMCID:: PMC5972310

Abstract Article PDF–1.6M

Select item 583701116.

Detection of experimental and clinical immune complexes by measuring SHIP-1 recruitment to the inhibitory FcγRIIB

Richard J. Stopforth, Robert J. Oldham, Alison L. Tutt, Patrick Duriez, H. T. Claude Chan, Brock F. Binkowski, Chad Zimprich, Dun Li, Philip G. Hargreaves, Mei Cong, Venkat Reddy, Maria J. Leandro, Geraldine Cambridge, Anja Lux, Falk Nimmerjahn, Mark S. Cragg

J Immunol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: J Immunol. 2018 Mar 1; 200(5): 1937–1950. Published online 2018 Jan 19. doi: 10.4049/jimmunol.1700832

PMCID:: PMC5837011

Abstract Article PDF–1.7M

Select item 486818217.

Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia

J Khalife, HS Radomska, R Santhanam, X Huang, P Neviani, J Saultz, H Wang, Y-Z Wu, H Alachkar, M Anghelina, A Dorrance, J Curfman, CD Bloomfield, BC Medeiros, D Perrotti, LJ Lee, RJ Lee, MA Caligiuri, F Pichiorri, CM Croce, R Garzon, ML Guzman, JH Mendler, G Marcucci

Leukemia. Author manuscript; available in PMC 2016 May 16.

Published in final edited form as: Leukemia. 2015 Oct; 29(10): 1981–1992. Published online 2015 May 14. doi: 10.1038/leu.2015.106

PMCID:: PMC4868182

Abstract Article PDF–1.3M

Select item 461581418.

The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies

Patrick Ehm, Marcus M Nalaskowski, Torsten Wundenberg, Manfred Jücker

Nucleus. 2015; 6(2): 154–164. Published online 2015 Feb 27. doi: 10.1080/19491034.2015.1022701

PMCID:: PMC4615814

Abstract Article PDF–972K

Select item 399382419.

MicroRNA 155 Regulates Japanese Encephalitis Virus-Induced Inflammatory Response by Targeting Src Homology 2-Containing Inositol Phosphatase 1

Menaka Chanu Thounaojam, Kiran Kundu, Deepak Kumar Kaushik, Shalini Swaroop, Anita Mahadevan, Susarla Krishna Shankar, Anirban Basu

J Virol. 2014 May; 88(9): 4798–4810. doi: 10.1128/JVI.02979-13

PMCID:: PMC3993824

Abstract Article PDF–2.9M

Select item 388214420.

Tks5 and SHIP2 Regulate Invadopodium Maturation, but Not Initiation, in Breast Carcinoma Cells

Ved P. Sharma, Robert Eddy, David Entenberg, Masayuki Kai, Frank B. Gertler, John Condeelis

Curr Biol. Author manuscript; available in PMC 2014 Nov 4.

Published in final edited form as: Curr Biol. 2013 Nov 4; 23(21): 10.1016/j.cub.2013.08.044. Published online 2013 Oct 24. doi: 10.1016/j.cub.2013.08.044

PMCID:: PMC3882144

Abstract Article PDF–5.0M

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