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Select item 30393441.

Human Inositol 1,4,5-Trisphosphate 3-Kinase Isoform B (IP3KB) Is a Nucleocytoplasmic Shuttling Protein Specifically Enriched at Cortical Actin Filaments and at Invaginations of the Nuclear Envelope

Marcus M. Nalaskowski, Ralf Fliegert, Olga Ernst, Maria A. Brehm, Werner Fanick, Sabine Windhorst, Hongying Lin, Susanne Giehler, Jamin Hein, Yuan-Na Lin, Georg W. Mayr

J Biol Chem. 2011 Feb 11; 286(6): 4500–4510. Published online 2010 Dec 9. doi: 10.1074/jbc.M110.173062

PMCID:: PMC3039344

Abstract Article PDF–2.2M

Select item 12215082.

Effects of elevated expression of inositol 1,4,5-trisphosphate 3-kinase B on Ca2+ homoeostasis in HeLa cells.

T H Millard, P J Cullen, G Banting

Biochem J. 2000 Dec 15; 352(Pt 3): 709–715.

PMCID:: PMC1221508

Summary PDF–144K

Select item 109125093.

Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis

Yuanliang Yan, Shangjun Zhou, Xi Chen, Qiaoli Yi, Songshan Feng, Zijin Zhao, Yuanhong Liu, Qiuju Liang, Zhijie Xu, Zhi Li, Lunquan Sun

Signal Transduct Target Ther. 2024; 9: 58. Published online 2024 Mar 4. doi: 10.1038/s41392-024-01763-x

PMCID:: PMC10912509

Abstract Article PDF–5.9M

Select item 65464694.

Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance

Chaoyun Pan, Lingtao Jin, Xu Wang, Yuancheng Li, Jaemoo Chun, Austin C. Boese, Dan Li, Hee-Bum Kang, Guojing Zhang, Lu Zhou, Georgia Z. Chen, Nabil F. Saba, Dong M. Shin, Kelly R. Magliocca, Taofeek K. Owonikoko, Hui Mao, Sagar Lonial, Sumin Kang

J Clin Invest. 2019 Jun 3; 129(6): 2431–2445. Published online 2019 May 13. doi: 10.1172/JCI124550

PMCID:: PMC6546469

Abstract Article PDF–6.8M

Select item 50644565.

miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells

Renxiong Wei, Gang Cao, Zhouming Deng, Jiajia Su, Lin Cai

Biosci Rep. 2016 Oct; 36(5): e00392. Prepublished online 2016 Aug 31. Published online 2016 Oct 14. doi: 10.1042/BSR20160238

PMCID:: PMC5064456

Abstract Article PDF–1.0M

Select item 99162936.

Increased Levels of the Parkinson’s Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status

Francesca Di Leva, Michele Filosi, Lisa Oyston, Erica Silvestri, Anne Picard, Alexandros A. Lavdas, Evy Lobbestael, Veerle Baekelandt, G. Gregory Neely, Peter P. Pramstaller, Andrew A. Hicks, Corrado Corti

Int J Mol Sci. 2023 Feb; 24(3): 1984. Published online 2023 Jan 19. doi: 10.3390/ijms24031984

PMCID:: PMC9916293

Abstract Article PDF–2.1M

Select item 50098077.

miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain

Evgenia Salta, Annerieke Sierksma, Elke Vanden Eynden, Bart De Strooper

EMBO Mol Med. 2016 Sep; 8(9): 1005–1018. Published online 2016 Aug 2. doi: 10.15252/emmm.201606520

PMCID:: PMC5009807

Abstract Article PDF–2.7M

Select item 12235738.

The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.

Valérie Dewaste, Colette Moreau, Florence De Smedt, Françoise Bex, Humbert De Smedt, Frank Wuytack, Ludwig Missiaen, Christophe Erneux

Biochem J. 2003 Aug 15; 374(Pt 1): 41–49. doi: 10.1042/BJ20021963

PMCID:: PMC1223573

Summary PDF–349K

Select item 11514299.

Molecular cloning and expression of a new putative inositol 1,4,5-trisphosphate 3-kinase isoenzyme.

K Takazawa, J Perret, J E Dumont, C Erneux

Biochem J. 1991 Sep 15; 278(Pt 3): 883–886. doi: 10.1042/bj2780883

PMCID:: PMC1151429

Summary Page Browse PDF–601K

Select item 114966310.

Cloning and expression in Escherichia coli of a rat brain cDNA encoding a Ca2+/calmodulin-sensitive inositol 1,4,5-trisphosphate 3-kinase.

K Takazawa, J Vandekerckhove, J E Dumont, C Erneux

Biochem J. 1990 Nov 15; 272(1): 107–112. doi: 10.1042/bj2720107

PMCID:: PMC1149663

Summary Page Browse PDF–1.1M

Select item 351082111.

Headpiece Domain of Dematin Regulates Calcium Mobilization and Signaling in Platelets

Adam J. Wieschhaus, Guy C. Le Breton, Athar H. Chishti

J Biol Chem. 2012 Nov 30; 287(49): 41218–41231. Published online 2012 Oct 11. doi: 10.1074/jbc.M112.364679

PMCID:: PMC3510821

Abstract Article PDF–2.8M

Select item 1013835612.

Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk

Andrea Gelemanović, Tatjana Ćatipović Ardalić, Ajka Pribisalić, Caroline Hayward, Ivana Kolčić, Ozren Polašek

Int J Mol Sci. 2023 Apr; 24(8): 7006. Published online 2023 Apr 10. doi: 10.3390/ijms24087006

PMCID:: PMC10138356

Abstract Article PDF–825K

Select item 886469513.

Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications

Antonieta L. Salguero, Maggie Chen, Aaron T. Balana, Nam Chu, Hanjie Jiang, Brad A. Palanski, Hwan Bae, Katharine M. Wright, Sara Nathan, Heng Zhu, Sandra B. Gabelli, Matthew R. Pratt, Philip A. Cole

ACS Chem Biol. Author manuscript; available in PMC 2022 Feb 23.

Published in final edited form as: ACS Chem Biol. 2022 Jan 21; 17(1): 68–76. Published online 2021 Dec 23. doi: 10.1021/acschembio.1c00632

PMCID:: PMC8864695

Abstract Article PDF–1.1M

Select item 334973414.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

Select item 660091515.

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116

Correction in:: Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.

PMCID:: PMC6600915

Abstract Article PDF–1.7M

Select item 318838816.

Leveraging the power of next-generation sequencing to generate interactome datasets

Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597

PMCID:: PMC3188388

Abstract Article PDF–932K

Select item 549522517.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 268304718.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 583915819.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 294516820.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

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