PMC Links for Gene (Select 3776) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 44

<< First< Prev

Page of 3

Select item 62793581.

TREK-1 channels regulate pressure sensitivity and calcium signaling in trabecular meshwork cells

Oleg Yarishkin, Tam T.T. Phuong, Colin A. Bretz, Kenneth W. Olsen, Jackson M. Baumann, Monika Lakk, Alan Crandall, Catherine Heurteaux, Mary E. Hartnett, David Križaj

J Gen Physiol. 2018 Dec 3; 150(12): 1660–1675. doi: 10.1085/jgp.201812179

PMCID:: PMC6279358

Abstract Article PDF–2.6M

Select item 61485482.

Altered expression and modulation of the two-pore-domain (K_2P) mechanogated potassium channel TREK-1 in overactive human detrusor

Ricardo H. Pineda, Balachandar Nedumaran, Joseph Hypolite, Xiao-Qing Pan, Shandra Wilson, Randall B. Meacham, Anna P. Malykhina

Am J Physiol Renal Physiol. 2017 Aug 1; 313(2): F535–F546. Published online 2017 May 24. doi: 10.1152/ajprenal.00638.2016

PMCID:: PMC6148548

Abstract Article

Select item 59606393.

Adaptive Reduction of Human Myometrium Contractile Activity in Response to Prolonged Uterine Stretch during Term and Twin Pregnancy. Role of TREK-1 Channel

Zongzhi Yin, Wenzhu He, Yun Li, Dan Li, Hongyan Li, Yuanyuan Yang, Zhaolian Wei, Bing Shen, Xi Wang, Yunxia Cao, Raouf A. Khalil

Biochem Pharmacol. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Biochem Pharmacol. 2018 Jun; 152: 252–263. Published online 2018 Mar 22. doi: 10.1016/j.bcp.2018.03.021

PMCID:: PMC5960639

Abstract Article PDF–1.0M

Select item 53767574.

Sodium permeable and “hypersensitive” TREK‐1 channels cause ventricular tachycardia

Niels Decher, Beatriz Ortiz‐Bonnin, Corinna Friedrich, Marcus Schewe, Aytug K Kiper, Susanne Rinné, Gunnar Seemann, Rémi Peyronnet, Sven Zumhagen, Daniel Bustos, Jens Kockskämper, Peter Kohl, Steffen Just, Wendy González, Thomas Baukrowitz, Birgit Stallmeyer, Eric Schulze‐Bahr

EMBO Mol Med. 2017 Apr; 9(4): 403–414. Published online 2017 Feb 27. doi: 10.15252/emmm.201606690

PMCID:: PMC5376757

Abstract Article PDF–1.7M

Select item 50221015.

Over-expressed human TREK-1 inhibits CHO cell proliferation via inhibiting PKA and p38 MAPK pathways and subsequently inducing G₁ arrest

Man Zhang, Hua-jing Yin, Wei-ping Wang, Jiang Li, Xiao-liang Wang

Acta Pharmacol Sin. 2016 Sep; 37(9): 1190–1198. Published online 2016 Jul 11. doi: 10.1038/aps.2016.65

PMCID:: PMC5022101

Abstract Article PDF–1.7M

Select item 47120076.

Alternatively Spliced Human TREK-1 Variants Alter TREK-1 Channel Function and Localization

Chad L. Cowles, Yi-Ying Wu, Scott D. Barnett, Michael T. Lee, Heather R. Burkin, Iain L.O. Buxton

Biol Reprod. 2015 Nov; 93(5): 122. Published online 2015 Sep 23. doi: 10.1095/biolreprod.115.129791

PMCID:: PMC4712007

Abstract Article PDF–918K

Select item 46219037.

Prognostic significance of the TREK-1 K2P potassium channels in prostate cancer

Gui-Ming Zhang, Fang-Ning Wan, Xiao-Jian Qin, Da-Long Cao, Hai-Liang Zhang, Yao Zhu, Bo Dai, Guo-Hai Shi, Ding-Wei Ye

Oncotarget. 2015 Jul 30; 6(21): 18460–18468. Published online 2015 Apr 21. doi: 10.18632/oncotarget.3782

PMCID:: PMC4621903

Abstract Article PDF–2.3M

Select item 42146578.

Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K_2P) mechano-gated potassium channel

Qi Lei, Xiao-Qing Pan, Shaohua Chang, S Bruce Malkowicz, Thomas J Guzzo, Anna P Malykhina

J Physiol. 2014 Jul 15; 592(Pt 14): 3013–3030. Published online 2014 May 6. doi: 10.1113/jphysiol.2014.271718

PMCID:: PMC4214657

Abstract Article PDF–2.0M

Select item 39297199.

The 2-Pore Domain Potassium Channel TREK-1 Regulates Stretch-Induced Detachment of Alveolar Epithelial Cells

Esra Roan, Christopher M. Waters, Bin Teng, Manik Ghosh, Andreas Schwingshackl

PLoS One. 2014; 9(2): e89429. Published online 2014 Feb 19. doi: 10.1371/journal.pone.0089429

PMCID:: PMC3929719

Abstract Article PDF–3.2M

Select item 376117410.

TREK-1 currents in smooth muscle cells from pregnant human myometrium

Nathanael S. Heyman, Chad L. Cowles, Scott D. Barnett, Yi-Ying Wu, Charles Cullison, Cherie A. Singer, Normand Leblanc, Iain L. O. Buxton

Am J Physiol Cell Physiol. 2013 Sep 15; 305(6): C632–C642. Published online 2013 Jun 26. doi: 10.1152/ajpcell.00324.2012

PMCID:: PMC3761174

Abstract Article

Select item 350754711.

Variants of Stretch-Activated Two-Pore Potassium Channel TREK-1 Associated with Preterm Labor in Humans

Yi-Ying Wu, Cherie A. Singer, Iain L.O. Buxton

Biol Reprod. 2012 Oct; 87(4): 96. Published online 2012 Jul 18. doi: 10.1095/biolreprod.112.099499

PMCID:: PMC3507547

Abstract Article PDF–2.5M

Select item 322054812.

External Ba²⁺ Block of the Two-pore Domain Potassium Channel TREK-1 Defines Conformational Transition in Its Selectivity Filter

Xiao-Yun Ma, Jin-Mei Yu, Shu-Zhuo Zhang, Xiao-Yan Liu, Bao-Hong Wu, Xiao-Li Wei, Jia-Qing Yan, Hong-Liang Sun, Hai-Tao Yan, Jian-Quan Zheng

J Biol Chem. 2011 Nov 18; 286(46): 39813–39822. Published online 2011 Sep 30. doi: 10.1074/jbc.M111.264788

PMCID:: PMC3220548

Abstract Article PDF–3.5M

Select item 157606413.

Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine

Louise E Kennard, Justin R Chumbley, Kishani M Ranatunga, Stephanie J Armstrong, Emma L Veale, Alistair Mathie

Br J Pharmacol. 2005 Mar; 144(6): 821–829. Published online 2005 Jan 31. doi: 10.1038/sj.bjp.0706068

PMCID:: PMC1576064

Abstract Article PDF–743K

Select item 999897714.

High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy

Tengteng Li, Jiajia Fei, Huihui Yu, Xingxing Wang, Jingjing Bai, Fucai Chen, Dan Li, Zongzhi Yin

Front Endocrinol (Lausanne) 2023; 14: 1115619. Published online 2023 Feb 27. doi: 10.3389/fendo.2023.1115619

Correction in:: Front Endocrinol (Lausanne). 2023; 14: 1200774.

PMCID:: PMC9998977

Abstract Article PDF–3.3M

Select item 982948315.

Activation of TREK-1 (K_2P2.1) potassium channels protects against influenza A-induced lung injury

Tatiana Zyrianova, Benjamin Lopez, Kathlyn Zou, Charles Gu, Dayna Pham, Sriharsha Talapaneni, Christopher M. Waters, Riccardo Olcese, Andreas Schwingshackl

Am J Physiol Lung Cell Mol Physiol. 2023 Jan 1; 324(1): L64–L75. Published online 2022 Nov 21. doi: 10.1152/ajplung.00116.2022