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Select item 97966211.

Diversity of NKG2C genotypes in a European population: Conserved and recombinant haplotypes in the coding, promoter, and 3′‐untranslated regions

Judit Asenjo, Manuela Moraru, Karima Al‐Akioui‐Sanz, Mireia Altadill, Aura Muntasell, Miguel López‐Botet, Carlos Vilches

HLA. 2022 Nov; 100(5): 469–478. Published online 2022 Jul 20. doi: 10.1111/tan.14734

PMCID:: PMC9796621

Abstract Article PDF–1.7M

Select item 91480692.

NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme

Shafiq Murad, Susanne Michen, Alexander Becker, Monika Füssel, Gabriele Schackert, Torsten Tonn, Frank Momburg, Achim Temme

Int J Mol Sci. 2022 May; 23(10): 5857. Published online 2022 May 23. doi: 10.3390/ijms23105857

PMCID:: PMC9148069

Abstract Article PDF–5.8M

Select item 89381633.

Assessment of NKG2C copy number variation in HIV-1 infection susceptibility, and considerations about the potential role of lacking receptors and virus infection

Bruno Toson, Rafael T. Michita, Maria C. T. Matte, Robson Soares, Gabriela K. S. Lawisch, Vanessa S. Mattevi, José A. B. Chies

J Hum Genet. 2022; 67(8): 475–479. Published online 2022 Mar 22. doi: 10.1038/s10038-022-01029-w

PMCID:: PMC8938163

Abstract Article PDF–397K

Select item 88558174.

Donor NKG2C homozygosity contributes to CMV clearance after haploidentical transplantation

Xing-Xing Yu, Qian-Nan Shang, Xue-Fei Liu, Mei He, Xu-Ying Pei, Xiao-Dong Mo, Meng Lv, Ting-Ting Han, Ming-Rui Huo, Xiao-Su Zhao, Ying-Jun Chang, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu, Kai-Yan Liu, Xiang-Yu Zhao, Xiao-Jun Huang

JCI Insight. 2022 Feb 8; 7(3): e149120. Published online 2022 Feb 8. doi: 10.1172/jci.insight.149120

PMCID:: PMC8855817

Abstract Article PDF–6.4M

Select item 83128705.

Influence of NKG2C Genotypes on HIV Susceptibility and Viral Load Set Point

Khlood Alsulami, Naomi Bolastig, Franck P. Dupuy, Tsoarello Mabanga, Louise Gilbert, Zahra Kiani, Jean-Pierre Routy, Julie Bruneau, Réjean Thomas, Cécile Tremblay, Christos M. Tsoukas, Jason Szabo, Pierre Côté, Benoit Trottier, Roger LeBlanc, Danielle Rouleau, Nicole F. Bernard

J Virol. 2021 Aug; 95(16): e00417-21. Prepublished online 2021 Jun 2. Published online 2021 Jul 26. doi: 10.1128/JVI.00417-21

PMCID:: PMC8312870

Abstract Article PDF–1.2M

Select item 79217996.

Surface NKG2C Identifies Differentiated αβT-Cell Clones Expanded in Peripheral Blood

Elena I. Kovalenko, Ivan V. Zvyagin, Maria A. Streltsova, Artem I. Mikelov, Sofya A. Erokhina, William G. Telford, Alexander M. Sapozhnikov, Yury B. Lebedev

Front Immunol. 2020; 11: 613882. Published online 2021 Feb 16. doi: 10.3389/fimmu.2020.613882

PMCID:: PMC7921799

Abstract Article PDF–2.5M

Select item 78356687.

Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19

Hannes Vietzen, Alexander Zoufaly, Marianna Traugott, Judith Aberle, Stephan W. Aberle, Elisabeth Puchhammer-Stöckl

Genet Med. 2021 May; 23(5): 963–967. Published online 2021 Sep 5. doi: 10.1038/s41436-020-01077-7

PMCID:: PMC7835668

Abstract Article PDF–434K

Select item 70575828.

Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients

Sergi Pascual-Guardia, Michelle Ataya, Isabel Ramírez-Martínez, José Yélamos, Roberto Chalela, Salomé Bellido, Miguel López-Botet, Joaquim Gea

Respir Res. 2020; 21: 63. Published online 2020 Mar 4. doi: 10.1186/s12931-020-1323-4

PMCID:: PMC7057582

Abstract Article PDF–883K

Select item 62062679.

Donor NKG2C Copy Number: An Independent Predictor for CMV Reactivation After Double Cord Blood Transplantation

Kai Cao, David Marin, Takuye Sekine, Gabriela Rondon, Weicheng Zhao, Nathaniel T. Smith, May Daher, Qing Wang, Li Li, Rima M. Saliba, Ravi Pingali, Uday Popat, Chitra Hosing, Amanda Olson, Betul Oran, Rafet Basar, Rohtesh S. Mehta, Richard Champlin, Elizabeth J. Shpall, Katayoun Rezvani

Front Immunol. 2018; 9: 2444. Published online 2018 Oct 23. doi: 10.3389/fimmu.2018.02444

PMCID:: PMC6206267

Abstract Article PDF–377K

Select item 494748410.

Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data

Adriana Goncalves, Pateh Makalo, Hassan Joof, Sarah Burr, Athumani Ramadhani, Patrick Massae, Aiweda Malisa, Tara Mtuy, Tamsyn Derrick, Anna R. Last, Meno Nabicassa, Eunice Cassama, Joanna Houghton, Christine D. Palmer, Harry Pickering, Matthew J. Burton, David C. W. Mabey, Robin L. Bailey, Martin R. Goodier, Martin J. Holland, Chrissy h. Roberts

Hum Genet. 2016; 135: 939–951. Published online 2016 Jun 16. doi: 10.1007/s00439-016-1694-2

PMCID:: PMC4947484

Abstract Article PDF–691K

Select item 420695311.

Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions

Martin R. Goodier, Matthew J. White, Alansana Darboe, Carolyn M. Nielsen, Adriana Goncalves, Christian Bottomley, Sophie E. Moore, Eleanor M. Riley

Blood. 2014 Oct 2; 124(14): 2213–2222. Prepublished online 2014 Aug 22. doi: 10.1182/blood-2014-05-576124

PMCID:: PMC4206953

Abstract Article

Select item 339956212.

NKG2C Deletion Is a Risk Factor of HIV Infection

Rachel Thomas, Hui Zhi Low, Katja Kniesch, Roland Jacobs, Reinhold E. Schmidt, Torsten Witte

AIDS Res Hum Retroviruses. 2012 Aug; 28(8): 844–851. doi: 10.1089/aid.2011.0253

PMCID:: PMC3399562

Abstract Article PDF–379K

Select item 316916013.

Expansion of a unique CD57⁺NKG2C^hi natural killer cell subset during acute human cytomegalovirus infection

Sandra Lopez-Vergès, Jeffrey M. Milush, Brian S. Schwartz, Marcelo J. Pando, Jessica Jarjoura, Vanessa A. York, Jeffrey P. Houchins, Steve Miller, Sang-Mo Kang, Phillip J. Norris, Douglas F. Nixon, Lewis L. Lanier

Proc Natl Acad Sci U S A. 2011 Sep 6; 108(36): 14725–14732. Published online 2011 Aug 8. doi: 10.1073/pnas.1110900108

PMCID:: PMC3169160

Abstract Article PDF–997K

Select item 1032097914.

Characterization of large-scale genomic differences in the first complete human genome

Xiangyu Yang, Xuankai Wang, Yawen Zou, Shilong Zhang, Manying Xia, Lianting Fu, Mitchell R. Vollger, Nae-Chyun Chen, Dylan J. Taylor, William T. Harvey, Glennis A. Logsdon, Dan Meng, Junfeng Shi, Rajiv C. McCoy, Michael C. Schatz, Weidong Li, Evan E. Eichler, Qing Lu, Yafei Mao

Genome Biol. 2023; 24: 157. Published online 2023 Jul 4. doi: 10.1186/s13059-023-02995-w

PMCID:: PMC10320979

Abstract Article PDF–2.7M

Select item 690846815.

Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C

Kyung Hwan Kim, Hee Tae Yu, Ilwoong Hwang, Sungha Park, Su-Hyung Park, Sungjin Kim, Eui-Cheol Shin

Front Immunol. 2019; 10: 2865. Published online 2019 Dec 6. doi: 10.3389/fimmu.2019.02865

PMCID:: PMC6908468

Abstract Article PDF–1.9M

Select item 485856516.

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans

Lisa L. Liu, Johannes Landskron, Eivind H. Ask, Monika Enqvist, Ebba Sohlberg, James A. Traherne, Quirin Hammer, Jodie P. Goodridge, Stella Larsson, Jyothi Jayaraman, Vincent Y.S. Oei, Marie Schaffer, Kjetil Taskén, Hans-Gustaf Ljunggren, Chiara Romagnani, John Trowsdale, Karl-Johan Malmberg, Vivien Béziat

Cell Rep. 2016 May 3; 15(5): 1088–1099. Published online 2016 Apr 21. doi: 10.1016/j.celrep.2016.04.005

PMCID:: PMC4858565

Abstract Article PDF–3.9M

Select item 401352717.

NKG2C^hiCD57⁺ Natural Killer cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus

Deborah W. Hendricks, Henry H. Balfour, Jr., Samantha K. Dunmire, David O. Schmeling, Kristin A. Hogquist, Lewis L. Lanier

J Immunol. Author manuscript; available in PMC 2015 May 15.

Published in final edited form as: J Immunol. 2014 May 15; 192(10): 4492–4496. Published online 2014 Apr 16. doi: 10.4049/jimmunol.1303211

PMCID:: PMC4013527

Abstract Article PDF–536K

Select item 381344118.

Deletion of the Activating NKG2C Receptor and a Functional Polymorphism in its Ligand HLA-E in Psoriasis Susceptibility

Xue Zeng, Haoyan Chen, Rashmi Gupta, Oscar Paz-Altschul, Anne M. Bowcock, Wilson Liao

Exp Dermatol. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Exp Dermatol. 2013 Oct; 22(10): 10.1111/exd.12233. doi: 10.1111/exd.12233

PMCID:: PMC3813441

Abstract Article PDF–37K

Select item 370027519.

Human Cytomegalovirus-Induced NKG2C^hi CD57^hi Natural Killer Cells Are Effectors Dependent on Humoral Antiviral Immunity

Zeguang Wu, Christian Sinzger, Giada Frascaroli, Johanna Reichel, Carina Bayer, Li Wang, Reinhold Schirmbeck, Thomas Mertens

J Virol. 2013 Jul; 87(13): 7717–7725. doi: 10.1128/JVI.01096-13

PMCID:: PMC3700275

Abstract Article PDF–1.5M

Select item 1069043720.

HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses

Zhansong Lin, Arman A. Bashirova, Mathias Viard, Lee Garner, Max Quastel, Maya Beiersdorfer, Wojciech K. Kasprzak, Marjan Akdag, Yuko Yuki, Pedro Ojeda, Sudipto Das, Thorkell Andresson, Vivek Naranbhai, Amir Horowitz, Andrew J. McMichael, Angelique Hoelzemer, Geraldine M. Gillespie, Wilfredo F. Garcia-Beltran, Mary Carrington

Nat Immunol. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Nat Immunol. 2023 Jul; 24(7): 1087–1097. Published online 2023 Jun 1. doi: 10.1038/s41590-023-01523-z

PMCID:: PMC10690437

Abstract Article PDF–3.3M

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