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Select item 109884941.

High preoperative bradykinin level is a risk factor for severe postoperative hypoxaemia in acute aortic dissection surgery

XinLiang Guan, Lei Li, JinZhang Li, WenJian Jiang, HaiYang Li, XiaoLong Wang, Lu Han, YuYong Liu, Ming Gong, HongJia Zhang

Exp Physiol. 2023 May; 108(5): 683–691. Published online 2023 Mar 19. doi: 10.1113/EP091054

PMCID:: PMC10988494

Abstract Article PDF–390K

Select item 104357662.

An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation

Bin Zhang, Haijun Han, Xinyi Zhao, Andria N. Li, Yan Wang, Wenji Yuan, Zhongli Yang, Ming D. Li

eBioMedicine. 2023 Aug; 94: 104694. Published online 2023 Jul 11. doi: 10.1016/j.ebiom.2023.104694

PMCID:: PMC10435766

Abstract Article PDF–2.6M

Select item 76458183.

Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection

Steven de Maat, Quirijn de Mast, A.H. Jan Danser, Frank L. van de Veerdonk, Coen Maas

Semin Thromb Hemost. 2020 Oct; 46(7): 835–837. Published online 2020 Jun 11. doi: 10.1055/s-0040-1712960

PMCID:: PMC7645818

Article PDF–134K

Select item 75984174.

Pathways for bradykinin formation and interrelationship with complement as a cause of edematous lung in COVID-19 patients

Allen P. Kaplan, Berhane Ghebrehiwet

J Allergy Clin Immunol. 2021 Feb; 147(2): 507–509. Published online 2020 Oct 28. doi: 10.1016/j.jaci.2020.10.025

PMCID:: PMC7598417

Article PDF–809K

Select item 72675065.

A hypothesized role for dysregulated bradykinin signaling in COVID‐19 respiratory complications

Joseph A. Roche, Renuka Roche

FASEB J. 2020 Jun; 34(6): 7265–7269. Published online 2020 May 2. doi: 10.1096/fj.202000967

PMCID:: PMC7267506

Abstract Article PDF–494K

Select item 70185356.

Differential Processing of High-Molecular-Weight Kininogen during Normal Pregnancy

Stephenie H. Droll, Yen-Michael Sheng Hsu, Steven K. Drake, Ashley Kim, Weixin Wang, Katherine R. Calvo, Zheng Cao, Tony Y Hu, Zhen Zhao

Rapid Commun Mass Spectrom. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Rapid Commun Mass Spectrom. 2020 Apr; 34(Suppl 1): e8552. Published online 2020 Feb 11. doi: 10.1002/rcm.8552

PMCID:: PMC7018535

Abstract Article PDF–671K

Select item 60909127.

Overexpression of the Kininogen-1 inhibits proliferation and induces apoptosis of glioma cells

Jinfang Xu, Jun Fang, Zhonghao Cheng, Longlong Fan, Weiwei Hu, Feng Zhou, Hong Shen

J Exp Clin Cancer Res. 2018; 37: 180. Published online 2018 Aug 2. doi: 10.1186/s13046-018-0833-0

PMCID:: PMC6090912

Abstract Article PDF–9.0M

Select item 51789938.

The Central Role of KNG1 Gene as a Genetic Determinant of Coagulation Pathway-Related Traits: Exploring Metaphenotypes

Helena Brunel, Raimon Massanet, Angel Martinez-Perez, Andrey Ziyatdinov, Laura Martin-Fernandez, Juan Carlos Souto, Alexandre Perera, José Manuel Soria

PLoS One. 2016; 11(12): e0167187. Published online 2016 Dec 22. doi: 10.1371/journal.pone.0167187

PMCID:: PMC5178993

Abstract Article PDF–1.8M

Select item 31678919.

Interaction of Bacteroides fragilis and Bacteroides thetaiotaomicron with the kallikrein–kinin system

Elizabeth C. Murphy, Matthias Mörgelin, Jakki C. Cooney, Inga-Maria Frick

Microbiology (Reading) 2011 Jul; 157(Pt 7): 2094–2105. doi: 10.1099/mic.0.046862-0

PMCID:: PMC3167891

Abstract Article PDF–472K

Select item 274734210.

Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study

Maja Barbalic, Gary L. Schwartz, Arlene B. Chapman, Stephen T. Turner, Eric Boerwinkle

Physiol Genomics. 2009 Sep; 39(1): 56–60. Published online 2009 Jul 7. doi: 10.1152/physiolgenomics.00061.2009

PMCID:: PMC2747342

Abstract Article

Select item 114836211.

Arrangement of the disulphide bridges in human low-Mr kininogen.

J Kellermann, C Thelen, F Lottspeich, A Henschen, R Vogel, W Müller-Esterl

Biochem J. 1987 Oct 1; 247(1): 15–21. doi: 10.1042/bj2470015

PMCID:: PMC1148362

Summary Page Browse PDF–1.6M

Select item 43701212.

High-molecular weight kininogen. A secreted platelet protein.

A H Schmaier, A Zuckerberg, C Silverman, J Kuchibhotla, G P Tuszynski, R W Colman

J Clin Invest. 1983 May; 71(5): 1477–1489. doi: 10.1172/JCI110901

PMCID:: PMC437012

Summary Page Browse PDF–2.5M

Select item 33314413.

Williams trait. Human kininogen deficiency with diminished levels of plasminogen proactivator and prekallikrein associated with abnormalities of the Hageman factor-dependent pathways.

R W Colman, A Bagdasarian, R C Talamo, C F Scott, M Seavey, J A Guimaraes, J V Pierce, A P Kaplan

J Clin Invest. 1975 Dec; 56(6): 1650–1662. doi: 10.1172/JCI108247

PMCID:: PMC333144

Summary Page Browse PDF–2.2M

Select item 682589814.

Prospective study of plasma high molecular weight kininogen and prekallikrein and incidence of coronary heart disease, ischemic stroke and heart failure

Romil R. Parikh, Aaron R. Folsom, Jeffrey R. Misialek, Wayne D. Rosamond, Patricia P. Chang, Weihong Tang, Mary Cushman

Thromb Res. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Thromb Res. 2019 Oct; 182: 89–94. Published online 2019 Aug 22. doi: 10.1016/j.thromres.2019.08.009

PMCID:: PMC6825898

Abstract Article PDF–259K

Select item 625590415.

Genetic effects of BDKRB2 and KNG1 on deep venous thrombosis after orthopedic surgery and the potential mediator

Qingfeng Wang, Guoping Cheng, Xiaohui Wang, Dandan Wang, Yanmei Yang, Ke Chen, Jiumin Ye, Zhong Qing

Sci Rep. 2018; 8: 17332. Published online 2018 Nov 26. doi: 10.1038/s41598-018-34868-9

PMCID:: PMC6255904

Abstract Article PDF–1.3M

Select item 472618116.

Urinary Kininogen-1 and Retinol binding protein-4 respond to Acute Kidney Injury: predictors of patient prognosis?

Laura Gonzalez-Calero, Marta Martin-Lorenzo, Angeles Ramos-Barron, Jorge Ruiz-Criado, Aroa S. Maroto, Alberto Ortiz, Carlos Gomez-Alamillo, Manuel Arias, Fernando Vivanco, Gloria Alvarez-Llamas

Sci Rep. 2016; 6: 19667. Published online 2016 Jan 21. doi: 10.1038/srep19667

PMCID:: PMC4726181

Abstract Article PDF–681K

Select item 439422717.

From proteomic multimarker profiling to interesting proteins: thymosin-β₄ and kininogen-1 as new potential biomarkers for inflammatory hepatic lesions

Corinna Henkel, Kristina Schwamborn, Henning W Zimmermann, Frank Tacke, Elisabeth Kühnen, Margarete Odenthal, M Reid Groseclose, Richard M Caprioli, Ralf Weiskirchen

J Cell Mol Med. 2011 Oct; 15(10): 2176–2188. Published online 2011 Sep 26. doi: 10.1111/j.1582-4934.2010.01204.x

PMCID:: PMC4394227

Abstract Article PDF–1.1M

Select item 435488018.

Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association with the Kininogen 1 and Prekallikrein Genes

Wolfgang Lieb, Ming-Huei Chen, Alexander Teumer, Rudolf A. de Boer, Honghuang Lin, Ervin R. Fox, Solomon K. Musani, James G. Wilson, Thomas J. Wang, Henry Völzke, Ann-Kristin Petersen, Christine Meisinger, Matthias Nauck, Sabrina Schlesinger, Yong Li, Jöel Menard, Serge Hercberg, H.-Erich Wichmann, Uwe Völker, Rajesh Rawal, Martin Bidlingmaier, Anke Hannemann, Marcus Dörr, Rainer Rettig, Wiek H. van Gilst, Dirk J. van Veldhuisen, Stephan J.L. Bakker, Gerjan Navis, Henri Wallaschofski, Pierre Meneton, Pim van der Harst, Martin Reincke, Ramachandran S. Vasan, CKDGen Consortium, CKDGen Consortium, ICBP, EchoGen Consortium

Circ Cardiovasc Genet. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Circ Cardiovasc Genet. 2015 Feb; 8(1): 131–140. Published online 2014 Dec 4. doi: 10.1161/CIRCGENETICS.114.000613

PMCID:: PMC4354880

Abstract Article PDF–574K

Select item 313703119.

High Molecular Weight Kininogen Activates B₂ Receptor Signaling Pathway in Human Vascular Endothelial Cells

Dhaval Kolte, Noah Osman, Jia Yang, Zia Shariat-Madar

J Biol Chem. 2011 Jul 15; 286(28): 24561–24571. Published online 2011 May 17. doi: 10.1074/jbc.M110.211557

PMCID:: PMC3137031

Abstract Article PDF–1.2M

Select item 309685020.

Bradykinin Promotes the Chemotactic Invasion of Primary Brain Tumors

Vedrana Montana, Harald Sontheimer

J Neurosci. 2011 Mar 30; 31(13): 4858–4867. doi: 10.1523/JNEUROSCI.3825-10.2011

PMCID:: PMC3096850

Abstract Article PDF–2.0M

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