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Select item 110479451.

Mitotic Functions and Characters of KIF11 in Cancers

Wanting Gao, Junjie Lu, Zitao Yang, Enmin Li, Yufei Cao, Lei Xie

Biomolecules. 2024 Apr; 14(4): 386. Published online 2024 Mar 22. doi: 10.3390/biom14040386

PMCID:: PMC11047945

Abstract Article PDF–2.7M

Select item 109876652.

Human kinesin-5 KIF11 drives the helical motion of anti-parallel and parallel microtubules around each other

Laura Meißner, Lukas Niese, Irene Schüring, Aniruddha Mitra, Stefan Diez

EMBO J. 2024 Apr; 43(7): 1244–1256. Published online 2024 Feb 29. doi: 10.1038/s44318-024-00048-x

PMCID:: PMC10987665

Abstract Article PDF–4.7M

Select item 106202983.

KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia

Liwen Zhu, Chuqin Chen, Meiyun Kang, Xiaopeng Ma, Xiaoyan Sun, Yao Xue, Yongjun Fang

J Cancer Res Clin Oncol. 2023; 149(17): 15609–15622. Published online 2023 Sep 1. doi: 10.1007/s00432-023-05240-w

PMCID:: PMC10620298

Abstract Article PDF–4.4M

Select item 105003414.

Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability

Katie L. Dale, Jonathan W. Armond, Robert E. Hynds, Elina Vladimirou

J Cell Sci. 2022 Sep 1; 135(17): jcs260031. Published online 2022 Aug 30. doi: 10.1242/jcs.260031

PMCID:: PMC10500341

Abstract Article

Select item 98935235.

KIF11 As a Potential Pan-Cancer Immunological Biomarker Encompassing the Disease Staging, Prognoses, Tumor Microenvironment, and Therapeutic Responses

Xiuhong Guo, Li Zhou, Yuening Wu, Jingxiang Li

Oxid Med Cell Longev. 2022; 2022: 2764940. Published online 2022 Dec 16. doi: 10.1155/2022/2764940

PMCID:: PMC9893523

Abstract Article PDF–7.7M

Select item 94684336.

KIF11 manipulates SREBP2‐dependent mevalonate cross talk to promote tumor progression in pancreatic ductal adenocarcinoma

Xiang Gu, Qunshan Zhu, Guangyu Tian, Wenbo Song, Tao Wang, Ali Wang, Xiaojun Chen, Songbing Qin

Cancer Med. 2022 Sep; 11(17): 3282–3295. Published online 2022 May 26. doi: 10.1002/cam4.4683

PMCID:: PMC9468433

Abstract Article PDF–9.2M

Select item 90314427.

Update on the Phenotypic and Genotypic Spectrum of KIF11-Related Retinopathy

You Wang, Zhaotian Zhang, Li Huang, Limei Sun, Songshan Li, Ting Zhang, Xiaoyan Ding

Genes (Basel) 2022 Apr; 13(4): 713. Published online 2022 Apr 18. doi: 10.3390/genes13040713

PMCID:: PMC9031442

Abstract Article PDF–1.0M

Select item 85866818.

Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers

Yoshiki Murase, Hiroaki Ono, Kosuke Ogawa, Risa Yoshioka, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe

Cancer Sci. 2021 Nov; 112(11): 4641–4654. Published online 2021 Oct 2. doi: 10.1111/cas.15134

PMCID:: PMC8586681

Abstract Article PDF–2.0M

Select item 85163399.

The oral KIF11 inhibitor 4SC‐205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models

Marc Masanas, Nuria Masiá, Leticia Suárez‐Cabrera, Mireia Olivan, Aroa Soriano, Blanca Majem, Laura Devis‐Jauregui, Rebeca Burgos‐Panadero, Carlos Jiménez, Pau Rodriguez‐Sodupe, Ariadna Boloix, Ignasi Toledano, Gabriela Guillén, Alexandra Navarro, David Llobet‐Navas, Alberto Villanueva, Josep Sánchez de Toledo, Josep Roma, Rosa Noguera, Lucas Moreno, Rolf Krauss, Soledad Gallego, Anna Santamaria, Miguel F. Segura

Clin Transl Med. 2021 Oct; 11(10): e533. Published online 2021 Oct 14. doi: 10.1002/ctm2.533

PMCID:: PMC8516339

Article PDF–2.3M

Select item 841023310.

Identification of a novel mutation in KIF11 with functional analysis in a cohort of 516 familial patients with exudative vitreoretinopathy

Kezhou Wang, Xiang Zhang, Tian Tian, Peiquan Zhao

Mol Vis. 2021; 27: 528–541. Published online 2021 Sep 1.

PMCID:: PMC8410233

Abstract Article PDF–2.6M

Select item 830388111.

Eg5 as a Prognostic Biomarker and Potential Therapeutic Target for Hepatocellular Carcinoma

Yu-Yun Shao, Nai-Yun Sun, Yung-Ming Jeng, Yao-Ming Wu, Chiun Hsu, Chih-Hung Hsu, Hey-Chi Hsu, Ann-Lii Cheng, Zhong-Zhe Lin

Cells. 2021 Jul; 10(7): 1698. Published online 2021 Jul 5. doi: 10.3390/cells10071698

PMCID:: PMC8303881

Abstract Article PDF–2.0M

Select item 821244012.

Retinal Features of Family Members With Familial Exudative Vitreoretinopathy Caused By Mutations in KIF11 Gene

Hiroyuki Kondo, Itsuka Matsushita, Tatsuo Nagata, Etsuko Fujihara, Katsuhiro Hosono, Eiichi Uchio, Yoshihiro Hotta, Shunji Kusaka

Transl Vis Sci Technol. 2021 Jun; 10(7): 18. Published online 2021 Jun 15. doi: 10.1167/tvst.10.7.18

PMCID:: PMC8212440

Abstract Article PDF–2.4M

Select item 789357713.

KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer

Dang Wei, Bian Rui, Fan Qingquan, Cai Chen, Hu Yun ping, Song Xiaoling, Weng Hao, Gu Jun

Int J Biol Sci. 2021; 17(2): 514–526. Published online 2021 Jan 1. doi: 10.7150/ijbs.54074

PMCID:: PMC7893577

Abstract Article PDF–3.1M

Select item 780110414.

KIF11 Promotes Proliferation of Hepatocellular Carcinoma among Patients with Liver Cancers

Zhan-Dong Hu, Ying Jiang, Hong-Mei Sun, Jing-wen Wang, Li-Li Zhai, Zhi-Qi Yin, Jun Yan

Biomed Res Int. 2021; 2021: 2676745. Published online 2021 Jan 4. doi: 10.1155/2021/2676745

PMCID:: PMC7801104

Abstract Article PDF–1.2M

Select item 743490215.

An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics

Abigail A. Zalenski, Shubhra Majumder, Kuntal De, Monica Venere

Sci Rep. 2020; 10: 13946. Published online 2020 Aug 18. doi: 10.1038/s41598-020-70787-4

PMCID:: PMC7434902

Abstract Article PDF–4.0M

Select item 713921716.

Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy

Alejandro Peña, Aaron Sweeney, Alexander D. Cook, Maya Topf, Carolyn A. Moores

Structure. 2020 Apr 7; 28(4): 450–457.e5. doi: 10.1016/j.str.2020.01.013

Correction in:: Structure. 2021 Jul 1; 29(7): 778.

PMCID:: PMC7139217

Abstract Article

Select item 663921817.

KIF11 Functions as an Oncogene and Is Associated with Poor Outcomes from Breast Cancer

Juan Zhou, Wei-Rong Chen, Li-Chao Yang, Jun Wang, Jia-Yuan Sun, Wen-Wen Zhang, Zhen-Yu He, San-Gang Wu

Cancer Res Treat. 2019 Jul; 51(3): 1207–1221. Published online 2018 Dec 27. doi: 10.4143/crt.2018.460

PMCID:: PMC6639218

Abstract Article PDF–2.8M

Select item 658079318.

High kinesin family member 11 expression predicts poor prognosis in patients with clear cell renal cell carcinoma

Qin Jin, Yanfeng Dai, Yan Wang, Shu Zhang, Gang Liu

J Clin Pathol. 2019 May; 72(5): 354–362. Published online 2019 Feb 28. doi: 10.1136/jclinpath-2018-205390

PMCID:: PMC6580793

Abstract Article PDF–2.0M

Select item 629671019.

Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor

Eri Saeki, Shinji Yasuhira, Masahiko Shibazaki, Hiroshi Tada, Minoru Doita, Tomoyuki Masuda, Chihaya Maesawa

PLoS One. 2018; 13(12): e0209296. Published online 2018 Dec 17. doi: 10.1371/journal.pone.0209296

Correction in:: PLoS One. 2019; 14(2): e0212821.

PMCID:: PMC6296710

Abstract Article PDF–2.1M

Select item 626888220.

3D-QSAR Studies of Dihydropyrazole and Dihydropyrrole Derivatives as Inhibitors of Human Mitotic Kinesin Eg5 Based on Molecular Docking

Xingyan Luo, Mao Shu, Yuanqiang Wang, Jin Liu, Wenjuan Yang, Zhihua Lin

Molecules. 2012 Feb; 17(2): 2015–2029. Published online 2012 Feb 17. doi: 10.3390/molecules17022015

PMCID:: PMC6268882

Abstract Article PDF–501K

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