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Select item 105339051.

Lung extracellular matrix modulates KRT5⁺ basal cell activity in pulmonary fibrosis

Richard J. Hewitt, Franz Puttur, David C. A. Gaboriau, Frédéric Fercoq, Maryline Fresquet, William J. Traves, Laura L. Yates, Simone A. Walker, Philip L. Molyneaux, Samuel V. Kemp, Andrew G. Nicholson, Alexandra Rice, Edward Roberts, Rachel Lennon, Leo M. Carlin, Adam J. Byrne, Toby M. Maher, Clare M. Lloyd

Nat Commun. 2023; 14: 6039. Published online 2023 Sep 27. doi: 10.1038/s41467-023-41621-y

PMCID:: PMC10533905

Abstract Article PDF–6.4M

Select item 85356702.

A Familial Form of Epidermolysis Bullosa Simplex Associated with a Pathogenic Variant in KRT5

Francesco Paduano, Emma Colao, Teresa Grillone, Marco Flavio Michele Vismara, Rosario Amato, Steven Nisticò, Chiara Mignogna, Stefano Dastoli, Fernanda Fabiani, Rossella Zucco, Francesco Trapasso, Nicola Perrotti, Rodolfo Iuliano

Genes (Basel) 2021 Oct; 12(10): 1503. Published online 2021 Sep 25. doi: 10.3390/genes12101503

PMCID:: PMC8535670

Abstract Article PDF–1.8M

Select item 71944963.

Correlation between salivary estrogen levels and oral epithelial cytokeratin 5 expression

Juni Handajani, Nuraini Effendi, Wihaskoro Sosroseno

Version 2. F1000Res. 2020; 9: 186. Published online 2020 Apr 22. doi: 10.12688/f1000research.22536.2

PMCID:: PMC7194496

Abstract Article PDF–1.1M

Select item 70854584.

Cytokeratin 5 alters β-catenin dynamics in breast cancer cells

Olivia McGinn, Ashley V. Ward, Lynsey M. Fettig, Duncan Riley, Joshua Ivie, Kiran V. Paul, Peter Kabos, Jessica Finlay-Schultz, Carol A. Sartorius

Oncogene. Author manuscript; available in PMC 2020 Jul 27.

Published in final edited form as: Oncogene. 2020 Mar; 39(12): 2478–2492. Published online 2020 Jan 27. doi: 10.1038/s41388-020-1164-0

PMCID:: PMC7085458

Abstract Article PDF–2.8M

Select item 53922895.

Keratin 5 overexpression is associated with serous ovarian cancer recurrence and chemotherapy resistance

Carmela Ricciardelli, Noor A. Lokman, Carmen E. Pyragius, Miranda P. Ween, Anne M. Macpherson, Andrew Ruszkiewicz, Peter Hoffmann, Martin K. Oehler

Oncotarget. 2017 Mar 14; 8(11): 17819–17832. Published online 2017 Jan 27. doi: 10.18632/oncotarget.14867

PMCID:: PMC5392289

Abstract Article PDF–11M

Select item 38512936.

Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers

Peter Kabos, James M. Haughian, Xinshuo Wang, Wendy W. Dye, Christina Finlayson, Anthony Elias, Kathryn B. Horwitz, Carol A. Sartorius

Breast Cancer Res Treat. Author manuscript; available in PMC 2013 Dec 4.

Published in final edited form as: Breast Cancer Res Treat. 2011 Jul; 128(1): 10.1007/s10549-010-1078-6. Published online 2010 Jul 28. doi: 10.1007/s10549-010-1078-6

PMCID:: PMC3851293

Abstract Article PDF–994K

Select item 35496407.

Progesterone-Inducible Cytokeratin 5-Positive Cells in Luminal Breast Cancer Exhibit Progenitor Properties

Sunshine Daddario Axlund, Byong Hoon Yoo, Rachel B. Rosen, Jerome Schaack, Peter Kabos, Daniel V. LaBarbera, Carol A. Sartorius

Horm Cancer. 2013 Feb; 4(1): 36–49. Published online 2012 Nov 27. doi: 10.1007/s12672-012-0127-5

PMCID:: PMC3549640

Abstract Article PDF–820K

Select item 26919928.

Quantification of Cytokeratin 5 mRNA Expression in the Circulation of Healthy Human Subjects and after Lung Transplantation

Derek W. Nickerson, Angela P. Presson, Stephen S. Weigt, Aric L. Gregson, John A. Belperio, Brigitte N. Gomperts

PLoS One. 2009; 4(6): e5925. Published online 2009 Jun 16. doi: 10.1371/journal.pone.0005925

PMCID:: PMC2691992

Abstract Article PDF–377K

Select item 18011599.

Epidermolysis bullosa simplex: a keratin 5 mutation is a fully dominant allele in epidermal cytoskeleton function.

K Stephens, A Zlotogorski, L Smith, P Ehrlich, E Wijsman, R J Livingston, V P Sybert

Am J Hum Genet. 1995 Mar; 56(3): 577–585.

PMCID:: PMC1801159

Summary Page Browse PDF–3.1M

Select item 168324810.

Mapping of epidermolysis bullosa simplex mutation to chromosome 12.

M Ryynänen, R G Knowlton, J Uitto

Am J Hum Genet. 1991 Nov; 49(5): 978–984.

PMCID:: PMC1683248

Summary Page Browse PDF–1.3M

Select item 138029411.

Loss-of-Function Mutations in the Keratin 5 Gene Lead to Dowling-Degos Disease

Regina C. Betz, Laura Planko, Sibylle Eigelshoven, Sandra Hanneken, Sandra M. Pasternack, Heinrich Büssow, Kris Van Den Bogaert, Joerg Wenzel, Markus Braun-Falco, Arno Rütten, Michael A. Rogers, Thomas Ruzicka, Markus M. Nöthen, Thomas M. Magin, Roland Kruse

Am J Hum Genet. 2006 Mar; 78(3): 510–519. Published online 2006 Jan 19. doi: 10.1086/500850

PMCID:: PMC1380294

Abstract Article PDF–7.8M

Select item 55150412.

Defining the Properties of the Nonhelical Tail Domain in Type II Keratin 5: Insight from a Bullous Disease-causing Mutation

Li-Hong Gu, Pierre A. Coulombe

Mol Biol Cell. 2005 Mar; 16(3): 1427–1438. doi: 10.1091/mbc.E04-06-0498

PMCID:: PMC551504

Abstract Article PDF–790K

Select item 36315713.

Sequence and expression of a type II keratin, K5, in human epidermal cells.

R Lersch, E Fuchs

Mol Cell Biol. 1988 Jan; 8(1): 486–493. doi: 10.1128/mcb.8.1.486

PMCID:: PMC363157

Summary Page Browse PDF–2.2M

Select item 36242914.

Isolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise control.

R Lersch, V Stellmach, C Stocks, G Giudice, E Fuchs

Mol Cell Biol. 1989 Sep; 9(9): 3685–3697. doi: 10.1128/mcb.9.9.3685

PMCID:: PMC362429

Summary Page Browse PDF–3.3M

Select item 4714815.

The genetic basis of Weber-Cockayne epidermolysis bullosa simplex.

Y M Chan, Q C Yu, J D Fine, E Fuchs

Proc Natl Acad Sci U S A. 1993 Aug 1; 90(15): 7414–7418. doi: 10.1073/pnas.90.15.7414

PMCID:: PMC47148

Summary Page Browse PDF–1.8M

Select item 3859816.

The genetic basis of epidermolysis bullosa simplex with mottled pigmentation.

J Uttam, E Hutton, P A Coulombe, I Anton-Lamprecht, Q C Yu, T Gedde-Dahl, Jr, J D Fine, E Fuchs

Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17): 9079–9084. doi: 10.1073/pnas.93.17.9079

PMCID:: PMC38598

Summary Page Browse PDF–2.9M

Select item 1047648017.

TRIM29 knockdown prevented the colon cancer progression through decreasing the ubiquitination levels of KRT5

Lihui Sun, Dawei Wang, Zhenyu Chen, Xu Zhu

Open Life Sci. 2023; 18(1): 20220711. Published online 2023 Aug 30. doi: 10.1515/biol-2022-0711

PMCID:: PMC10476480

Abstract Article PDF–3.0M

Select item 944496518.

Cytokeratins 5 and 17 maintain an aggressive epithelial state in basal-like breast cancer

Olivia McGinn, Duncan Riley, Jessica Finlay-Schultz, Kiran V. Paul, Peter Kabos, Carol A. Sartorius

Mol Cancer Res. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: Mol Cancer Res. 2022 Sep 2; 20(9): 1443–1455. doi: 10.1158/1541-7786.MCR-21-0866

PMCID:: PMC9444965

Abstract Article PDF–2.3M

Select item 862417519.

Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex

Nadezhda A. Evtushenko, Arkadii K. Beilin, Anastasiya V. Kosykh, Ekaterina A. Vorotelyak, Nadya G. Gurskaya

Int J Mol Sci. 2021 Nov; 22(22): 12446. Published online 2021 Nov 18. doi: 10.3390/ijms222212446

PMCID:: PMC8624175

Abstract Article PDF–1.8M

Select item 846073720.

Inhibition of Notch activity promotes pancreatic cytokeratin 5-positive cell differentiation to beta cells and improves glucose homeostasis following acute pancreatitis

Xiaoyi Zhang, Jing Tao, Jia Yu, Ning Hu, Xuanzhe Zhang, Guirong Wang, Jiarui Feng, Xingcheng Xiong, Man Li, Dongqi Chai, Hanjun Li, Yuping Rong, Zhigang Tang, Weixing Wang, Zhiyong Peng, Qiao Shi

Cell Death Dis. 2021 Oct; 12(10): 867. Published online 2021 Sep 23. doi: 10.1038/s41419-021-04160-2