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Select item 110910361.

Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment

Peng Zhang, Yi Wan, Jinrong Ma, Jin Gong, Ziwei Zhong, Yuxin Cui, Hongli Zhang, Yanyan Da, Junpeng Ma, Chenxi Li, Lijuan Liu, Tian Gong, Youwen Tan, Chengsheng Zhang

Cancer Immunol Immunother. 2024 Jul; 73(7): 127. Published online 2024 May 13. doi: 10.1007/s00262-024-03717-2

PMCID:: PMC11091036

Abstract Article PDF–5.9M

Select item 82698302.

Testicular germ cell tumors type 2 have high RNA expression of LDHB, the gene for lactate dehydrogenase subunit B

Finn Edler von Eyben, Jorge Parraga-Alava, Shi-Ming Tu

Asian J Androl. 2021 Jul-Aug; 23(4): 357–362. Published online 2021 Feb 9. doi: 10.4103/aja.aja_4_21

PMCID:: PMC8269830

Abstract Article PDF–533K

Select item 73072553.

rs11046147 mutation in the promoter region of lactate dehydrogenase‐B as a potential predictor of prognosis in triple‐negative breast cancer

Jia Liu, Yue Li, Xiao‐Qiong Chen, Chang Sun, Xiu‐Li Sun, Zheng Yang, Qing‐Peng Kong

Cancer Commun (Lond) 2020 Jun; 40(6): 279–282. Published online 2020 May 20. doi: 10.1002/cac2.12031

PMCID:: PMC7307255

Article PDF–348K

Select item 65146374.

Lactic acidosis caused by repressed lactate dehydrogenase subunit B expression down-regulates mitochondrial oxidative phosphorylation via the pyruvate dehydrogenase (PDH)–PDH kinase axis

Sun Mi Hong, Young-Kyoung Lee, Imkyong Park, So Mee Kwon, Seongki Min, Gyesoon Yoon

J Biol Chem. 2019 May 10; 294(19): 7810–7820. Published online 2019 Mar 28. doi: 10.1074/jbc.RA118.006095

PMCID:: PMC6514637

Abstract Article PDF–2.9M

Select item 50691395.

Lactate Metabolism is Associated with Mammalian Mitochondria

Ying-Jr Chen, Nathaniel G. Mahieu, Xiaojing Huang, Manmilan Singh, Peter A Crawford, Stephen L. Johnson, Richard W. Gross, Jacob Schaefer, Gary J. Patti

Nat Chem Biol. Author manuscript; available in PMC 2017 Mar 12.

Published in final edited form as: Nat Chem Biol. 2016 Nov; 12(11): 937–943. Published online 2016 Sep 12. doi: 10.1038/nchembio.2172

PMCID:: PMC5069139

Abstract Article PDF–1.1M

Select item 44317276.

Lactate Dehydrogenase B Is Associated with the Response to Neoadjuvant Chemotherapy in Oral Squamous Cell Carcinoma

Wenyi Sun, Xiaomin Zhang, Xu Ding, Huaiqi Li, Meiyu Geng, Zuoquan Xie, Heming Wu, Min Huang

PLoS One. 2015; 10(5): e0125976. Published online 2015 May 14. doi: 10.1371/journal.pone.0125976

PMCID:: PMC4431727

Abstract Article PDF–4.8M

Select item 37271447.

Lactate Dehydrogenase B: A Metabolic Marker of Response to Neoadjuvant Chemotherapy in Breast Cancer

Jennifer B. Dennison, Jennifer R. Molina, Shreya Mitra, Ana M. González-Angulo, Justin M. Balko, María G. Kuba, Melinda E. Sanders, Joseph A. Pinto, Henry L. Gómez, Carlos L. Arteaga, Robert E. Brown, Gordon B. Mills

Clin Cancer Res. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Clin Cancer Res. 2013 Jul 1; 19(13): 3703–3713. Published online 2013 May 22. doi: 10.1158/1078-0432.CCR-13-0623

PMCID:: PMC3727144

Abstract Article PDF–1.8M

Select item 36120278.

Lactate dehydrogenase as a marker of nasopharyngeal inflammatory injury during viral upper respiratory infection: implications for acute otitis media

Linda C. Ede, James O’Brien, Tasnee Chonmaitree, Yimei Han, Janak A. Patel

Pediatr Res. 2013; 73(3): 349–354. Published online 2012 Nov 30. doi: 10.1038/pr.2012.179

PMCID:: PMC3612027

Abstract Article PDF–248K

Select item 35787889.

Lactate Dehydrogenase-B Is Silenced by Promoter Methylation in a High Frequency of Human Breast Cancers

Nicola J. Brown, Sue E. Higham, Branko Perunovic, Mohammad Arafa, Sabapathy Balasubramanian, Ishtiaq Rehman

PLoS One. 2013; 8(2): e57697. Published online 2013 Feb 21. doi: 10.1371/journal.pone.0057697

PMCID:: PMC3578788

Abstract Article PDF–567K

Select item 331288210.

The Role of LDH Serum Levels in Predicting Global Outcome in HCC Patients Undergoing TACE: Implications for Clinical Management

Mario Scartozzi, Luca Faloppi, Maristella Bianconi, Riccardo Giampieri, Elena Maccaroni, Alessandro Bittoni, Michela Del Prete, Cristian Loretelli, Laura Belvederesi, Gianluca Svegliati Baroni, Stefano Cascinu

PLoS One. 2012; 7(3): e32653. Published online 2012 Mar 26. doi: 10.1371/journal.pone.0032653

PMCID:: PMC3312882

Abstract Article PDF–140K

Select item 114863911.

The cDNA and protein sequences of human lactate dehydrogenase B.

I Sakai, F S Sharief, Y C Pan, S S Li

Biochem J. 1987 Dec 15; 248(3): 933–936. doi: 10.1042/bj2480933

PMCID:: PMC1148639

Summary Page Browse PDF–709K

Select item 113567612.

Structure of the human lactate dehydrogenase B gene.

T Takeno, S S Li

Biochem J. 1989 Feb 1; 257(3): 921–924. doi: 10.1042/bj2570921

PMCID:: PMC1135676

Summary Page Browse PDF–741K

Select item 1116442813.

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells

Federica Cuozzo, Katrina Viloria, Ali H. Shilleh, Daniela Nasteska, Charlotte Frazer-Morris, Jason Tong, Zicong Jiao, Adam Boufersaoui, Bryan Marzullo, Daniel B. Rosoff, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Paul R.V. Johnson, Rebecca Spiers, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo D.L. Ceresa, David W. Ray, Leanne Hodson, Amy P. Davies, Guy A. Rutter, Masaya Oshima, Raphaël Scharfmann, Matthew J. Merrins, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson

Cell Rep. Author manuscript; available in PMC 2024 Jun 10.

Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114047. Published online 2024 Apr 11. doi: 10.1016/j.celrep.2024.114047

PMCID:: PMC11164428

Abstract Article PDF–2.8M

Select item 1106904914.

Integrated analysis of single cell‐RNA sequencing and Mendelian randomization identifies lactate dehydrogenase B as a target of melatonin in ischemic stroke

Fei Shi, Guiyun Zhang, Jinshi Li, Liang Shu, Cong Yu, Dabin Ren, Yisong Zhang, Ping Zheng

CNS Neurosci Ther. 2024 May; 30(5): e14741. Published online 2024 May 3. doi: 10.1111/cns.14741

PMCID:: PMC11069049

Abstract Article PDF–8.2M

Select item 1040269815.

The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma

Jie Chen, Fei Wu, Yehua Cao, Yuanxin Xing, Qingyong Liu, Zuohui Zhao

PeerJ. 2023; 11: e15749. Published online 2023 Aug 1. doi: 10.7717/peerj.15749

PMCID:: PMC10402698

Abstract Article PDF–4.0M

Select item 843740716.

Streptococcus pneumoniae Binds to Host Lactate Dehydrogenase via PspA and PspC To Enhance Virulence

Sang-Sang Park, Norberto Gonzalez-Juarbe, Eriel Martínez, Joanetha Yvette Hale, Yi-Han Lin, Joshua T. Huffines, Katherine L. Kruckow, David E. Briles, Carlos J. Orihuela

mBio. 2021 May-Jun; 12(3): e00673-21. Published online 2021 May 4. doi: 10.1128/mBio.00673-21

PMCID:: PMC8437407

Abstract Article PDF–2.1M

Select item 841557717.

Association between serum lactate dehydrogenase and frailty among individuals with metabolic syndrome

Li-Hsiang Chen, Li-Wei Wu

PLoS One. 2021; 16(9): e0256315. Published online 2021 Sep 3. doi: 10.1371/journal.pone.0256315

PMCID:: PMC8415577

Abstract Article PDF–523K

Select item 821061218.

Lactate dehydrogenase B regulates macrophage metabolism in the tumor microenvironment

Ann-Christin Frank, Rebecca Raue, Dominik C. Fuhrmann, Evelyn Sirait-Fischer, Carsten Reuse, Andreas Weigert, Dieter Lütjohann, Karsten Hiller, Shahzad Nawaz Syed, Bernhard Brüne

Theranostics. 2021; 11(15): 7570–7588. Published online 2021 Jun 4. doi: 10.7150/thno.58380

PMCID:: PMC8210612

Abstract Article PDF–3.9M

Select item 636036419.

SIRT5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer

Liang Shi, Hui Yan, Shuxian An, Mengqin Shen, Wenzhi Jia, Ruixue Zhang, Li Zhao, Gang Huang, Jianjun Liu

Mol Oncol. 2019 Feb; 13(2): 358–375. Published online 2018 Dec 3. doi: 10.1002/1878-0261.12408

PMCID:: PMC6360364

Abstract Article PDF–1.4M

Select item 632290320.

LDHA and LDHB are dispensable for aerobic glycolysis in neuroblastoma cells while promoting their aggressiveness

Christian Beltinger

J Biol Chem. 2019 Jan 4; 294(1): 66. doi: 10.1074/jbc.L118.006717

PMCID:: PMC6322903

Article PDF–69K

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