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Select item 105151601.

Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment

Joel Gruchot, Isabel Lewen, Michael Dietrich, Laura Reiche, Mustafa Sindi, Christina Hecker, Felisa Herrero, Benjamin Charvet, Ulrike Weber-Stadlbauer, Hans-Peter Hartung, Philipp Albrecht, Hervé Perron, Urs Meyer, Patrick Küry

Proc Natl Acad Sci U S A. 2023 Sep 19; 120(38): e2308187120. Published online 2023 Sep 11. doi: 10.1073/pnas.2308187120

PMCID:: PMC10515160

Abstract Article PDF–11M

Select item 81168182.

HERV-W envelope expression in blood leukocytes as a marker of disease severity of COVID-19

Marta Garcia-Montojo, Avindra Nath

EBioMedicine. 2021 May; 67: 103363. Published online 2021 May 13. doi: 10.1016/j.ebiom.2021.103363

PMCID:: PMC8116818

Article PDF–389K

Select item 48530383.

Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2

Lina Cui, Huiying Wang, Xiaoyin Lu, Rui Wang, Ru Zheng, Yue Li, Xiaokui Yang, Wen-Tong Jia, Yangyu Zhao, Yongqing Wang, Haibin Wang, Yan-Ling Wang, Cheng Zhu, Hai-Yan Lin, Hongmei Wang

Cell Adh Migr. 2016 Jan-Apr; 10(1-2): 39–55. Published online 2016 Feb 6. doi: 10.1080/19336918.2015.1093720

PMCID:: PMC4853038

Abstract Article PDF–1.4M

Select item 43640254.

A CRE/AP-1-Like Motif Is Essential for Induced Syncytin-2 Expression and Fusion in Human Trophoblast-Like Model

Chirine Toufaily, Adjimon Gatien Lokossou, Amandine Vargas, Éric Rassart, Benoit Barbeau

PLoS One. 2015; 10(3): e0121468. Published online 2015 Mar 17. doi: 10.1371/journal.pone.0121468

PMCID:: PMC4364025

Abstract Article PDF–1.4M

Select item 22459795.

Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta

André Malassiné, Jean-Louis Frendo, Sandra Blaise, Karen Handschuh, Pascale Gerbaud, Vassilis Tsatsaris, Thierry Heidmann, Danièle Evain-Brion

Retrovirology. 2008; 5: 6. Published online 2008 Jan 23. doi: 10.1186/1742-4690-5-6

PMCID:: PMC2245979

Abstract Article PDF–928K

Select item 99171646.

Interaction between Long Noncoding RNAs and Syncytin-1/Syncytin-2 Genes and Transcripts: How Noncoding RNAs May Affect Pregnancy in Patients with Systemic Lupus Erythematosus

Rossella Talotta

Int J Mol Sci. 2023 Feb; 24(3): 2259. Published online 2023 Jan 23. doi: 10.3390/ijms24032259

PMCID:: PMC9917164

Abstract Article PDF–1005K

Select item 32035787.

Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin

Kateřina Trejbalová, Jana Blažková, Magda Matoušková, Dana Kučerová, Lubomíra Pecnová, Zdenka Vernerová, Jiří Heráček, Ivan Hirsch, Jiří Hejnar

Nucleic Acids Res. 2011 Nov; 39(20): 8728–8739. Published online 2011 Jul 19. doi: 10.1093/nar/gkr562

PMCID:: PMC3203578

Abstract Article PDF–1.0M

Select item 5243688.

Identification of endogenous retroviral reading frames in the human genome

Palle Villesen, Lars Aagaard, Carsten Wiuf, Finn Skou Pedersen

Retrovirology. 2004; 1: 32. Published online 2004 Oct 11. doi: 10.1186/1742-4690-1-32

PMCID:: PMC524368

Abstract Article PDF–687K

Select item 21544669.

Placental syncytins: Genetic disjunction between the fusogenic and immunosuppressive activity of retroviral envelope proteins

Marianne Mangeney, Martial Renard, Géraldine Schlecht-Louf, Isabelle Bouallaga, Odile Heidmann, Claire Letzelter, Aurélien Richaud, Bertrand Ducos, Thierry Heidmann

Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51): 20534–20539. Published online 2007 Dec 12. doi: 10.1073/pnas.0707873105

PMCID:: PMC2154466

Abstract Article PDF–682K

Select item 501019910.

Genetic Evidence That Captured Retroviral Envelope syncytins Contribute to Myoblast Fusion and Muscle Sexual Dimorphism in Mice

François Redelsperger, Najat Raddi, Agathe Bacquin, Cécile Vernochet, Virginie Mariot, Vincent Gache, Nicolas Blanchard-Gutton, Stéphanie Charrin, Laurent Tiret, Julie Dumonceaux, Anne Dupressoir, Thierry Heidmann

PLoS Genet. 2016 Sep; 12(9): e1006289. Published online 2016 Sep 2. doi: 10.1371/journal.pgen.1006289

PMCID:: PMC5010199

Abstract Article PDF–9.0M

Select item 36880811.

Identification of an Envelope Protein from the FRD Family of Human Endogenous Retroviruses (HERV-FRD) Conferring Infectivity and Functional Conservation among Simians

Sandra Blaise, Alessia Ruggieri, Marie Dewannieux, François-Loic Cosset, Thierry Heidmann

J Virol. 2004 Jan; 78(2): 1050–1054. doi: 10.1128/JVI.78.2.1050-1054.2004

PMCID:: PMC368808

Abstract Article PDF–1.2M

Select item 828025412.

Syncytins expressed in human placental trophoblast

R. Michael Roberts, Toshihiko Ezashi, Laura C. Schulz, Jun Sugimoto, Danny J. Schust, Teka Khan, Jie Zhou

Placenta. Author manuscript; available in PMC 2022 Sep 15.

Published in final edited form as: Placenta. 2021 Sep 15; 113: 8–14. Published online 2021 Jan 15. doi: 10.1016/j.placenta.2021.01.006

PMCID:: PMC8280254

Abstract Article PDF–752K

Select item 22846813.

Survey of Human Genes of Retroviral Origin: Identification and Transcriptome of the Genes with Coding Capacity for Complete Envelope Proteins

Nathalie de Parseval, Vladimir Lazar, Jean-François Casella, Laurence Benit, Thierry Heidmann

J Virol. 2003 Oct; 77(19): 10414–10422. doi: 10.1128/JVI.77.19.10414-10422.2003

PMCID:: PMC228468

Abstract Article PDF–1.6M

Select item 359800214.

A novel human endogenous retroviral protein inhibits cell-cell fusion

Jun Sugimoto, Makiko Sugimoto, Helene Bernstein, Yoshihiro Jinno, Danny Schust

Sci Rep. 2013; 3: 1462. Published online 2013 Mar 15. doi: 10.1038/srep01462

PMCID:: PMC3598002

Abstract Article PDF–2.3M

Select item 24073615.

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution

Sandra Blaise, Nathalie de Parseval, Laurence Bénit, Thierry Heidmann

Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22): 13013–13018. Published online 2003 Oct 13. doi: 10.1073/pnas.2132646100

PMCID:: PMC240736

Abstract Article PDF–458K

Select item 311391916.

A revised nomenclature for transcribed human endogenous retroviral loci

Jens Mayer, Jonas Blomberg, Ruth L Seal

Mob DNA. 2011; 2: 7. Published online 2011 May 4. doi: 10.1186/1759-8753-2-7

PMCID:: PMC3113919

Abstract Article PDF–298K

Select item 316943217.

Protein interactome reveals converging molecular pathways among autism disorders

Yasunari Sakai, Chad A. Shaw, Brian C. Dawson, Diana V. Dugas, Zaina Al-Mohtaseb, David E. Hill, Huda Y. Zoghbi

Sci Transl Med. Author manuscript; available in PMC 2011 Dec 8.

Published in final edited form as: Sci Transl Med. 2011 Jun 8; 3(86): 86ra49. doi: 10.1126/scitranslmed.3002166

PMCID:: PMC3169432

Abstract Article PDF–6.0M

Select item 40369718.

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski

Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003

Correction in:: Genome Res. 2003 Dec; 13(12): 2759.

PMCID:: PMC403697

Abstract Article PDF–120K

Select item 319082619.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 135612920.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

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