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Select item 85917761.

MXD1 is a Potential Prognostic Biomarker and Correlated With Specific Molecular Change and Tumor Microenvironment Feature in Esophageal Squamous Cell Carcinoma

Feng Du, Dezuo Dong, Xiaodong Zhang, Jun Jia

Technol Cancer Res Treat. 2021; 20: 15330338211052142. Published online 2021 Nov 11. doi: 10.1177/15330338211052142

PMCID:: PMC8591776

Abstract Article PDF–3.5M

Select item 53424962.

MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis

Maria del Carmen Lafita-Navarro, Rosa Blanco, Jorge Mata-Garrido, Judit Liaño-Pons, Olga Tapia, Lucía García-Gutiérrez, Eva García-Alegría, María T. Berciano, Miguel Lafarga, Javier León

Oncotarget. 2016 Oct 25; 7(43): 69536–69548. Published online 2016 Aug 31. doi: 10.18632/oncotarget.11766

PMCID:: PMC5342496

Abstract Article PDF–9.7M

Select item 50707203.

TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction

Suqin Shen, Jie Zuo, Huan Feng, Meirong Bai, Chenji Wang, Youheng Wei, Yanhong Li, Yichen Le, Jiaxue Wu, Yanhua Wu, Long Yu

BMB Rep. 2016 Jun 30; 49(6): 325–330. doi: 10.5483/BMBRep.2016.49.6.248

PMCID:: PMC5070720

Abstract Article PDF–7.1M

Select item 27834504.

The Suppression of MAD1 by AKT-Mediated Phosphorylation Activates MAD1 Target Genes Transcription

Chao-Kai Chou, Dung-Fang Lee, Hui-Lung Sun, Long-Yuan Li, Chun-Yi Lin, Wei-Chien Huang, Jung-Mao Hsu, Hsu-Ping Kuo, Hirohito Yamaguchi, Ying-Nai Wang, Mo Liu, Hsin-Yi Wu, Pao-Chi Liao, Chia-Jui Yen, Mien-Chie Hung

Mol Carcinog. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Mol Carcinog. 2009 Nov; 48(11): 1048–1058. doi: 10.1002/mc.20557

PMCID:: PMC2783450

Abstract Article PDF–786K

Select item 78476775.

Targeting miR-21 with NL101 blocks c-Myc/Mxd1 loop and inhibits the growth of B cell lymphoma

Shu Li, Xin He, Yichao Gan, Jiawei Zhang, Feiqiong Gao, Limin Lin, Xi Qiu, Teng Yu, Xuzhao Zhang, Panpan Chen, Jiefeng Tong, Wenbin Qian, Yang Xu

Theranostics. 2021; 11(7): 3439–3451. Published online 2021 Jan 19. doi: 10.7150/thno.53561

PMCID:: PMC7847677

Abstract Article PDF–2.1M

Select item 46230456.

Down regulation of miR-202 modulates Mxd1 and Sin3A repressor complexes to induce apoptosis of pancreatic cancer cells

Lulu Farhana, Marcia I Dawson, Joseph A Fontana

Cancer Biol Ther. 2015 Jan; 16(1): 115–124. Published online 2015 Jan 22. doi: 10.4161/15384047.2014.987070

PMCID:: PMC4623045

Abstract Article PDF–623K

Select item 39732217.

MiR-19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1

Q Wu, Z Yang, Y An, H Hu, J Yin, P Zhang, Y Nie, K Wu, Y Shi, D Fan

Cell Death Dis. 2014 Mar; 5(3): e1144. Published online 2014 Mar 27. doi: 10.1038/cddis.2014.110

PMCID:: PMC3973221

Abstract Article PDF–2.2M

Select item 29006978.

Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells

Eduardo F. Farias, Kevin Petrie, Boris Leibovitch, Janice Murtagh, Manuel Boix Chornet, Tino Schenk, Arthur Zelent, Samuel Waxman

Proc Natl Acad Sci U S A. 2010 Jun 29; 107(26): 11811–11816. Published online 2010 Jun 14. doi: 10.1073/pnas.1006737107

PMCID:: PMC2900697

Abstract Article PDF–1.1M

Select item 22751449.

Regulation of the MAD1 promoter by G-CSF

Kan Jiang, Nadine Hein, Kolja Eckert, Juliane Lüscher-Firzlaff, Bernhard Lüscher

Nucleic Acids Res. 2008 Mar; 36(5): 1517–1531. Published online 2008 Jan 18. doi: 10.1093/nar/gkn002

PMCID:: PMC2275144

Abstract Article PDF–320K

Select item 414344010.

Novel Genetic Variants Modify the Effect of Smoking on Carotid Plaque Burden in Hispanics

David Della-Morte, Liyong Wang, Ashley Beecham, Susan H. Blanton, Hongyu Zhao, Ralph L. Sacco, Tatjana Rundek, Chuanhui Dong

J Neurol Sci. Author manuscript; available in PMC 2015 Sep 15.

Published in final edited form as: J Neurol Sci. 2014 Sep 15; 344(0): 27–31. Published online 2014 Jun 14. doi: 10.1016/j.jns.2014.06.006

PMCID:: PMC4143440

Abstract Article PDF–315K

Select item 350315311.

Vitamin D receptor as a master regulator of the c-MYC/MXD1 network

Reyhaneh Salehi-Tabar, Loan Nguyen-Yamamoto, Luz E. Tavera-Mendoza, Thomas Quail, Vassil Dimitrov, Beum-Soo An, Leon Glass, David Goltzman, John H. White

Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46): 18827–18832. Published online 2012 Oct 29. doi: 10.1073/pnas.1210037109

PMCID:: PMC3503153

Abstract Article PDF–878K

Select item 237332512.

Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1

Jidong Zhu, John Blenis, Junying Yuan

Proc Natl Acad Sci U S A. 2008 May 6; 105(18): 6584–6589. Published online 2008 May 1. doi: 10.1073/pnas.0802785105

PMCID:: PMC2373325

Abstract Article PDF–857K

Select item 51450913.

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

Gretchen Poortinga, Katherine M Hannan, Hayley Snelling, Carl R Walkley, Anna Jenkins, Kerith Sharkey, Meaghan Wall, Yves Brandenburger, Manuela Palatsides, Richard B Pearson, Grant A McArthur, Ross D Hannan

EMBO J. 2004 Aug 18; 23(16): 3325–3335. Published online 2004 Jul 29. doi: 10.1038/sj.emboj.7600335

PMCID:: PMC514509

Abstract Article PDF–265K

Select item 314540614.

HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity

John D. Gordan, Jessica A. Bertovrt, Cheng-Jun Hu, J. Alan Diehl, M. Celeste Simon

Cancer Cell. Author manuscript; available in PMC 2011 Jul 28.

Published in final edited form as: Cancer Cell. 2007 Apr; 11(4): 335–347. doi: 10.1016/j.ccr.2007.02.006

PMCID:: PMC3145406

Abstract Article PDF–4.4M

Select item 13785915.

JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors

Clement M. Lee, Djamila Onésime, C. Damodara Reddy, N. Dhanasekaran, E. Premkumar Reddy

Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22): 14189–14194. Published online 2002 Oct 21. doi: 10.1073/pnas.232310199

PMCID:: PMC137859

Abstract Article PDF–400K

Select item 705334216.

The CARM1-p300-c-Myc-Max (CPCM) transcriptional complex regulates the expression of CUL4A/4B and affects the stability of CRL4 E3 ligases in colorectal cancer

Wenzhu Lu, Chunmei Yang, Hongbo He, Hong Liu

Int J Biol Sci. 2020; 16(6): 1071–1085. Published online 2020 Feb 4. doi: 10.7150/ijbs.41230

PMCID:: PMC7053342

Abstract Article PDF–2.5M

Select item 564024017.

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis

Jingwei Cheng, Donglim Esther Park, Christian Berrios, Elizabeth A. White, Reety Arora, Rosa Yoon, Timothy Branigan, Tengfei Xiao, Thomas Westerling, Alexander Federation, Rhamy Zeid, Benjamin Strober, Selene K. Swanson, Laurence Florens, James E. Bradner, Myles Brown, Peter M. Howley, Megha Padi, Michael P. Washburn, James A. DeCaprio

PLoS Pathog. 2017 Oct; 13(10): e1006668. Published online 2017 Oct 13. doi: 10.1371/journal.ppat.1006668

PMCID:: PMC5640240

Abstract Article PDF–9.9M

Select item 625176118.

Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders

Brent Wilkinson, Oleg Evgrafov, DongQing Zheng, Nicolas Hartel, James A. Knowles, Nicholas A. Graham, Justin Ichida, Marcelo P. Coba

Biol Psychiatry. Author manuscript; available in PMC 2020 Feb 15.

Published in final edited form as: Biol Psychiatry. 2019 Feb 15; 85(4): 305–316. Published online 2018 May 23. doi: 10.1016/j.biopsych.2018.05.009

PMCID:: PMC6251761

Abstract Article PDF–1.6M

Select item 381740419.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 732206720.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

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