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Items: 1 to 20 of 145

1.
Apoptosis signal-regulating kinase-1 regulates thrombin-induced endothelial permeability
Hemant Giri, Amit K. Srivastava, Ulhas P. Naik
Vascul Pharmacol. Author manuscript; available in PMC 2023 Jun 18.
Published in final edited form as: Vascul Pharmacol. 2022 Aug; 145: 107088. Published online 2022 Jul 4. doi: 10.1016/j.vph.2022.107088
PMCID:
PMC10276900
AbstractArticlePDF–2.0M
2.
Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions
Veronika Obsilova, Karolina Honzejkova, Tomas Obsil
Int J Mol Sci. 2021 Dec; 22(24): 13395. Published online 2021 Dec 13. doi: 10.3390/ijms222413395
PMCID:
PMC8705584
AbstractArticlePDF–1.8M
3.
Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibition Reduces Endothelial Cytokine Production without Improving Permeability after Toll-like Receptor 4 (TLR4) Challenge
Michael R. Miller, Stephen R. Koch, Hyehun Choi, Fred S. Lamb, Ryan J. Stark
Transl Res. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Transl Res. 2021 Sep; 235: 115–128. Published online 2021 Apr 20. doi: 10.1016/j.trsl.2021.04.001
PMCID:
PMC8328918
AbstractArticlePDF–2.0M
4.
Lifespan extension conferred by mitogen-activated protein kinase kinase kinase 5 (MAP3K5) longevity-associated gene variation is confined to at-risk men with a cardiometabolic disease
Brian J. Morris, Randi Chen, Timothy A. Donlon, Kamal H. Masaki, D. Craig Willcox, Richard C. Allsopp, Bradley J. Willcox
Aging (Albany NY) 2021 Mar 31; 13(6): 7953–7974. Published online 2021 Mar 19. doi: 10.18632/aging.202844
PMCID:
PMC8034933
AbstractArticlePDF–1.3M
5.
Apoptosis signal-regulating kinase 1 (ASK1) inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease (COPD)
Mathew S Eapen, Anudeep Kota, Howard Vindin, Kielan D McAlinden, Dia Xenaki, Brian G Oliver, Deepak A Deshpande, Sukhwinder Singh Sohal, Pawan Sharma
Clin Sci (Lond) Author manuscript; available in PMC 2018 Nov 5.
Published in final edited form as: Clin Sci (Lond). 2018 Jul 31; 132(14): 1615–1627. Published online 2018 Jul 31. doi: 10.1042/CS20180398
PMCID:
PMC6218165
AbstractArticlePDF–1.7M
6.
Dynamic phosphorylation of apoptosis signal regulating kinase 1 (ASK1) in response to oxidative and electrophilic stress
Carlos Morales Betanzos, Joel D. Federspiel, Amy M. Palubinsky, BethAnn McLaughlin, Daniel C. Liebler
Chem Res Toxicol. Author manuscript; available in PMC 2018 May 7.
Published in final edited form as: Chem Res Toxicol. 2016 Dec 19; 29(12): 2175–2183. Published online 2016 Nov 30. doi: 10.1021/acs.chemrestox.6b00339
PMCID:
PMC5937698
AbstractArticlePDF–896K
7.
Adenosine 5′-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation
Xiao Yang, Yibei Zhan, Qi Sun, Xi Xu, Yi Kong, Jianfa Zhang
Oncotarget. 2017 Jan 24; 8(4): 6273–6282. Published online 2016 Dec 21. doi: 10.18632/oncotarget.14059
PMCID:
PMC5351630
AbstractArticlePDF–8.6M
8.
MicroRNA-Mediated Down-Regulation of Apoptosis Signal-Regulating Kinase 1 (ASK1) Attenuates the Apoptosis of Human Mesenchymal Stem Cells (MSCs) Transplanted into Infarcted Heart
Chang Youn Lee, Sunhye Shin, Jiyun Lee, Hyang-Hee Seo, Kyu Hee Lim, Hyemin Kim, Jung-Won Choi, Sang Woo Kim, Seahyung Lee, Soyeon Lim, Ki-Chul Hwang
Int J Mol Sci. 2016 Oct; 17(10): 1752. Published online 2016 Oct 20. doi: 10.3390/ijms17101752
PMCID:
PMC5085777
AbstractArticlePDF–2.0M
9.
Variants in ASK1 Are Associated With Skeletal Muscle ASK1 Expression, In Vivo Insulin Resistance, and Type 2 Diabetes in Pima Indians
Li Bian, Robert L. Hanson, Victoria Ossowski, Kim Wiedrich, Clinton C. Mason, Michael Traurig, Yunhua L. Muller, Sayuko Kobes, William C. Knowler, Leslie J. Baier, Clifton Bogardus
Diabetes. 2010 May; 59(5): 1276–1282. Published online 2010 Feb 25. doi: 10.2337/db09-1700
PMCID:
PMC2857909
AbstractArticlePDF–175K
10.
Mechanisms of Trx2/ASK1-Mediated Mitochondrial Injury in Pemphigus Vulgaris
Bin Wei, Fenghe Li
Biomed Res Int. 2021; 2021: 2471518. Published online 2021 Feb 23. doi: 10.1155/2021/2471518
PMCID:
PMC7946479
AbstractArticlePDF–2.9M
11.
ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes
Pei-pei Fang, Chen-wei Pan, Wei Lin, Jie Li, Shan-shan Huang, Guang-yao Zhou, Wen-jun Du, Qiang Li
Mediators Inflamm. 2020; 2020: 8183713. Published online 2020 Nov 7. doi: 10.1155/2020/8183713
PMCID:
PMC7669360
AbstractArticlePDF–3.5M
12.
Liver ASK1 protects from non‐alcoholic fatty liver disease and fibrosis
Tenagne D Challa, Stephan Wueest, Fabrizio C Lucchini, Mara Dedual, Salvatore Modica, Marcela Borsigova, Christian Wolfrum, Matthias Blüher, Daniel Konrad
EMBO Mol Med. 2019 Oct; 11(10): e10124. Published online 2019 Jun 6. doi: 10.15252/emmm.201810124
PMCID:
PMC6783644
AbstractArticlePDF–1.7M
13.
Stress-Induced Activation of Apoptosis Signal-Regulating Kinase 1 Promotes Osteoarthritis
QIAN-SHI ZHANG, GREGORY J. EATON, CAROL DIALLO, THERESA A. FREEMAN
J Cell Physiol. Author manuscript; available in PMC 2018 May 15.
Published in final edited form as: J Cell Physiol. 2016 Apr; 231(4): 944–953. Published online 2015 Sep 29. doi: 10.1002/jcp.25186
PMCID:
PMC5952048
AbstractArticlePDF–1.6M
14.
Cold stress‐induced ferroptosis involves the ASK1‐p38 pathway
Kazuki Hattori, Hiroyuki Ishikawa, Chihiro Sakauchi, Saki Takayanagi, Isao Naguro, Hidenori Ichijo
EMBO Rep. 2017 Nov; 18(11): 2067–2078. Published online 2017 Sep 8. doi: 10.15252/embr.201744228
PMCID:
PMC5666609
AbstractArticlePDF–852K
15.
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
Yulia Haim, Matthias Blüher, Daniel Konrad, Nir Goldstein, Nora Klöting, Ilana Harman-Boehm, Boris Kirshtein, Doron Ginsberg, Tanya Tarnovscki, Yftach Gepner, Iris Shai, Assaf Rudich
Mol Metab. 2017 Jul; 6(7): 725–736. Published online 2017 May 6. doi: 10.1016/j.molmet.2017.05.003
PMCID:
PMC5485239
AbstractArticlePDF–2.3M
16.
Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma
Cai-Feng Jiang, Liang-Zhi Wen, Chuan Yin, Wen-Ping Xu, Bin Shi, Xin Zhang, Wei-Fen Xie
Oncotarget. 2016 May 10; 7(19): 27408–27421. Published online 2016 Mar 30. doi: 10.18632/oncotarget.8478
PMCID:
PMC5053659
AbstractArticlePDF–18M
17.
Structural Insight into the 14-3-3 Protein-dependent Inhibition of Protein Kinase ASK1 (Apoptosis Signal-regulating kinase 1)
Olivia Petrvalska, Dalibor Kosek, Zdenek Kukacka, Zdenek Tosner, Petr Man, Jaroslav Vecer, Petr Herman, Veronika Obsilova, Tomas Obsil
J Biol Chem. 2016 Sep 23; 291(39): 20753–20765. Published online 2016 Aug 11. doi: 10.1074/jbc.M116.724310
PMCID:
PMC5034064
AbstractArticlePDF–4.1M
18.
Cross-talk between Arg methylation and Ser phosphorylation modulates apoptosis signal–regulating kinase 1 activation in endothelial cells
Ming Chen, Xiaosheng Qu, Zhiqing Zhang, Huayu Wu, Xia Qin, Fuji Li, Zhenfang Liu, Liyuan Tian, Jianhua Miao, Wei Shu
Mol Biol Cell. 2016 Apr 15; 27(8): 1358–1366. doi: 10.1091/mbc.E15-10-0738
PMCID:
PMC4831888
AbstractArticlePDF–2.8M
19.
ASK1 signalling regulates brown and beige adipocyte function
Kazuki Hattori, Isao Naguro, Kohki Okabe, Takashi Funatsu, Shotaro Furutani, Kohsuke Takeda, Hidenori Ichijo
Nat Commun. 2016; 7: 11158. Published online 2016 Apr 5. doi: 10.1038/ncomms11158
PMCID:
PMC4822029
AbstractArticlePDF–1.9M
20.
Receptor tyrosine kinase‐like orphan receptor 1, a target of NKX2‐1/TTF‐1 lineage‐survival oncogene, inhibits apoptosis signal‐regulating kinase 1‐mediated pro‐apoptotic signaling in lung adenocarcinoma
Lisa Ida, Tomoya Yamaguchi, Kiyoshi Yanagisawa, Taisuke Kajino, Yukako Shimada, Motoshi Suzuki, Takashi Takahashi
Cancer Sci. 2016 Feb; 107(2): 155–161. Published online 2016 Feb 8. doi: 10.1111/cas.12858
PMCID:
PMC4768386
AbstractArticlePDF–1.2M

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