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Select item 445541.

Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia.

R Prasad, D Leshkowitz, Y Gu, H Alder, T Nakamura, H Saito, K Huebner, R Berger, C M Croce, E Canaani

Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17): 8107–8111. doi: 10.1073/pnas.91.17.8107

PMCID:: PMC44554

Summary Page Browse PDF–1.0M

Select item 77268062.

MLLT6 maintains PD‐L1 expression and mediates tumor immune resistance

Sandeep Sreevalsan, Marietta Döring, Maciej Paszkowski‐Rogacz, Melanie Brux, Carolina Blanck, Marten Meyer, Frank Momburg, Frank Buchholz, Mirko Theis

EMBO Rep. 2020 Dec 3; 21(12): e50155. Published online 2020 Oct 15. doi: 10.15252/embr.202050155

PMCID:: PMC7726806

Abstract Article PDF–2.2M

Select item 31037273.

Af17 Deficiency Increases Sodium Excretion and Decreases Blood Pressure

Lihe Chen, Hongyu Wu, Oleh M. Pochynyuk, Mary Rose Reisenauer, Zhijing Zhang, Le Huang, Oleg Leonidovych Zaika, Mykola Mamenko, Weiru Zhang, Qiaoling Zhou, Mingyao Liu, Yang Xia, Wenzheng Zhang

J Am Soc Nephrol. 2011 Jun; 22(6): 1076–1086. doi: 10.1681/ASN.2010121270

PMCID:: PMC3103727

Abstract Article

Select item 46092904.

The PZP domain of AF10 senses unmodified H3K27 to regulate DOT1L-mediated methylation of H3K79

Shoudeng Chen, Ze Yang, Alex W. Wilkinson, Aniruddha J. Deshpande, Simone Sidoli, Krzysztof Krajewski, Brian D. Strahl, Benjamin A. Garcia, Scott A. Armstrong, Dinshaw J. Patel, Or Gozani

Mol Cell. Author manuscript; available in PMC 2016 Oct 15.

Published in final edited form as: Mol Cell. 2015 Oct 15; 60(2): 319–327. Published online 2015 Oct 1. doi: 10.1016/j.molcel.2015.08.019

PMCID:: PMC4609290

Abstract Article PDF–1.3M

Select item 27909975.

AF17 Competes with AF9 for Binding to Dot1a to Up-regulate Transcription of Epithelial Na⁺ Channel α

Mary Rose Reisenauer, Marc Anderson, Le Huang, Zhijing Zhang, Qiaoling Zhou, Bruce C. Kone, Andrew P. Morris, Gene D. LeSage, Stuart E. Dryer, Wenzheng Zhang

J Biol Chem. 2009 Dec 18; 284(51): 35659–35669. Published online 2009 Oct 28. doi: 10.1074/jbc.M109.038448

PMCID:: PMC2790997

Abstract Article PDF–1.8M

Select item 28413356.

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)

Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P. Washburn, Laurence Florens, Ali Shilatifard

Genes Dev. 2010 Mar 15; 24(6): 574–589. doi: 10.1101/gad.1898410

PMCID:: PMC2841335

Abstract Article PDF–1.1M

Select item 28083327.

Expanding the Substantial Interactome of NEMO Using Protein Microarrays

Beau J. Fenner, Michael Scannell, Jochen H. M. Prehn

PLoS One. 2010; 5(1): e8799. Published online 2010 Jan 20. doi: 10.1371/journal.pone.0008799

PMCID:: PMC2808332

Abstract Article PDF–509K

Select item 87690728.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 43584039.

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt

Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi

Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115

PMCID:: PMC4358403

Abstract Article PDF–1.4M

Select item 954034510.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 970808611.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 484160712.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 822039113.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 926261414.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 545599615.

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

Cell Syst. Author manuscript; available in PMC 2017 Sep 28.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001

PMCID:: PMC5455996

Abstract Article PDF–3.1M

Select item 882889516.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 268304717.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 732206718.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 300858619.

Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics

Eric J. Bennett, John Rush, Steven P. Gygi, J. Wade Harper

Cell. Author manuscript; available in PMC 2011 Dec 10.

Published in final edited form as: Cell. 2010 Dec 10; 143(6): 951–965. doi: 10.1016/j.cell.2010.11.017

PMCID:: PMC3008586

Abstract Article PDF–3.0M

Select item 1056587620.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644