PMC Links for Gene (Select 438) - PMC

Select item 60522371.

Restoration of hydroxyindole O-methyltransferase levels in human cancer cells induces a tryptophan-metabolic switch and attenuates cancer progression

Hua-Ling Chen, Chao-Yun Yuan, Huei-Hsuan Cheng, Tzu-Ching Chang, Shau-Ku Huang, Cheng-Chin Kuo, Kenneth K. Wu

J Biol Chem. 2018 Jul 13; 293(28): 11131–11142. Published online 2018 May 24. doi: 10.1074/jbc.RA117.000597

PMCID:: PMC6052237

Abstract Article PDF–3.3M

Select item 40529422.

ASMT gene expression correlates with cognitive impairment in patients with recurrent depressive disorder

Monika Talarowska, Janusz Szemraj, Marlena Zajączkowska, Piotr Gałecki

Med Sci Monit. 2014; 20: 905–912. Published online 2014 Jun 2. doi: 10.12659/MSM.890160

PMCID:: PMC4052942

Abstract Article PDF–444K

Select item 35479423.

Sequencing ASMT Identifies Rare Mutations in Chinese Han Patients with Autism

Lifang Wang, Jun Li, Yanyan Ruan, Tianlan Lu, Chenxing Liu, Meixiang Jia, Weihua Yue, Jing Liu, Thomas Bourgeron, Dai Zhang

PLoS One. 2013; 8(1): e53727. Published online 2013 Jan 17. doi: 10.1371/journal.pone.0053727

PMCID:: PMC3547942

Abstract Article PDF–224K

Select item 30346654.

Mutation screening of ASMT, the last enzyme of the melatonin pathway, in a large sample of patients with Intellectual Disability

Cecile Pagan, Hany Goubran Botros, Karine Poirier, Anne Dumaine, Stéphane Jamain, Sarah Moreno, Arjan de Brouwer, Hilde Van Esch, Richard Delorme, Jean-Marie Launay, Andreas Tzschach, Vera Kalscheuer, Didier Lacombe, Sylvain Briault, Frédéric Laumonnier, Martine Raynaud, Bregje W van Bon, Marjolein H Willemsen, Marion Leboyer, Jamel Chelly, Thomas Bourgeron

BMC Med Genet. 2011; 12: 17. Published online 2011 Jan 20. doi: 10.1186/1471-2350-12-17

PMCID:: PMC3034665

Abstract Article PDF–226K

Select item 21992645.

Abnormal melatonin synthesis in autism spectrum disorders

Jonas Melke, Hany Goubran-Botros, Pauline Chaste, Catalina Betancur, Gudrun Nygren, Henrik Anckarsäter, Maria Rastam, Ola Ståhlberg, I. Carina Gillberg, Richard Delorme, Nadia Chabane, Marie-Christine Mouren-Simeoni, Fabien Fauchereau, Christelle M. Durand, Fabien Chevalier, Xavier Drouot, Corinne Collet, Jean-Marie Launay, Marion Leboyer, Christopher Gillberg, Thomas Bourgeron, the PARIS study

Mol Psychiatry. Author manuscript; available in PMC 2008 Jan 31.

Published in final edited form as: Mol Psychiatry. 2008 Jan; 13(1): 90–98. Published online 2007 May 15. doi: 10.1038/sj.mp.4002016

PMCID:: PMC2199264

Abstract Article

Select item 42891086.

Genetic Variation in Melatonin Pathway Enzymes in Children with Autism Spectrum Disorder and Comorbid Sleep Onset Delay

Olivia J. Veatch, Julie S. Pendergast, Melissa J. Allen, Roberta M. Leu, Carl Hirschie Johnson, Sarah H. Elsea, Beth A. Malow

J Autism Dev Disord. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: J Autism Dev Disord. 2015 Jan; 45(1): 100–110. doi: 10.1007/s10803-014-2197-4

PMCID:: PMC4289108

Abstract Article PDF–837K

Select item 31915577.

Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma; its synthesis is reduced favoring cholangiocarcinoma growth

Yuyan Han, Sharon DeMorrow, Pietro Invernizzi, Qing Jing, Shannon Glaser, Anastasia Renzi, Fanyin Meng, Julie Venter, Francesca Bernuzzi, Mellanie White, Heather Francis, Ana Lleo, Marco Marzioni, Paolo Onori, Domenico Alvaro, Guido Torzilli, Eugenio Gaudio, Gianfranco Alpini

Am J Physiol Gastrointest Liver Physiol. 2011 Oct; 301(4): G623–G633. Published online 2011 Jul 21. doi: 10.1152/ajpgi.00118.2011

PMCID:: PMC3191557

Abstract Article

Select item 30206298.

Mutation screening of melatonin-related genes in patients with autism spectrum disorders

Lina Jonsson, Elin Ljunggren, Anna Bremer, Christin Pedersen, Mikael Landén, Kent Thuresson, MaiBritt Giacobini, Jonas Melke

BMC Med Genomics. 2010; 3: 10. Published online 2010 Apr 8. doi: 10.1186/1755-8794-3-10

PMCID:: PMC3020629

Abstract Article PDF–1.1M

Select item 29874129.

Linkage and candidate gene studies of autism spectrum disorders in European populations

Richard Holt, Gabrielle Barnby, Elena Maestrini, Elena Bacchelli, Denise Brocklebank, Inês Sousa, Erik J Mulder, Katri Kantojärvi, Irma Järvelä, Sabine M Klauck, Fritz Poustka, Anthony J Bailey, Anthony P Monaco, the EU Autism MOLGEN Consortium

Eur J Hum Genet. 2010 Sep; 18(9): 1013–1019. Published online 2010 May 5. doi: 10.1038/ejhg.2010.69

Correction in:: Eur J Hum Genet. 2010 Sep; 18(9): 1020.

PMCID:: PMC2987412

Abstract Article PDF–592K

Select item 555930610.

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627

PMCID:: PMC5559306

Abstract Article PDF–885K

Select item 266528611.

The DNA sequence of the human X chromosome

Mark T. Ross, Darren V. Grafham, Alison J. Coffey, Steven Scherer, Kirsten McLay, Donna Muzny, Matthias Platzer, Gareth R. Howell, Christine Burrows, Christine P. Bird, Adam Frankish, Frances L. Lovell, Kevin L. Howe, Jennifer L. Ashurst, Robert S. Fulton, Ralf Sudbrak, Gaiping Wen, Matthew C. Jones, Matthew E. Hurles, T. Daniel Andrews, Carol E. Scott, Stephen Searle, Juliane Ramser, Adam Whittaker, Rebecca Deadman, Nigel P. Carter, Sarah E. Hunt, Rui Chen, Andrew Cree, Preethi Gunaratne, Paul Havlak, Anne Hodgson, Michael L. Metzker, Stephen Richards, Graham Scott, David Steffen, Erica Sodergren, David A. Wheeler, Kim C. Worley, Rachael Ainscough, Kerrie D. Ambrose, M. Ali Ansari-Lari, Swaroop Aradhya, Robert I. S. Ashwell, Anne K. Babbage, Claire L. Bagguley, Andrea Ballabio, Ruby Banerjee, Gary E. Barker, Karen F. Barlow, Ian P. Barrett, Karen N. Bates, David M. Beare, Helen Beasley, Oliver Beasley, Alfred Beck, Graeme Bethel, Karin Blechschmidt, Nicola Brady, Sarah Bray-Allen, Anne M. Bridgeman, Andrew J. Brown, Mary J. Brown, David Bonnin, Elspeth A. Bruford, Christian Buhay, Paula Burch, Deborah Burford, Joanne Burgess, Wayne Burrill, John Burton, Jackie M. Bye, Carol Carder, Laura Carrel, Joseph Chako, Joanne C. Chapman, Dean Chavez, Ellson Chen, Guan Chen, Yuan Chen, Zhijian Chen, Craig Chinault, Alfredo Ciccodicola, Sue Y. Clark, Graham Clarke, Chris M. Clee, Sheila Clegg, Kerstin Clerc-Blankenburg, Karen Clifford, Vicky Cobley, Charlotte G. Cole, Jen S. Conquer, Nicole Corby, Richard E. Connor, Robert David, Joy Davies, Clay Davis, John Davis, Oliver Delgado, Denise DeShazo, Pawandeep Dhami, Yan Ding, Huyen Dinh, Steve Dodsworth, Heather Draper, Shannon Dugan-Rocha, Andrew Dunham, Matthew Dunn, K. James Durbin, Ireena Dutta, Tamsin Eades, Matthew Ellwood, Alexandra Emery-Cohen, Helen Errington, Kathryn L. Evans, Louisa Faulkner, Fiona Francis, John Frankland, Audrey E. Fraser, Petra Galgoczy, James Gilbert, Rachel Gill, Gernot Glöckner, Simon G. Gregory, Susan Gribble, Coline Griffiths, Russell Grocock, Yanghong Gu, Rhian Gwilliam, Cerissa Hamilton, Elizabeth A. Hart, Alicia Hawes, Paul D. Heath, Katja Heitmann, Steffen Hennig, Judith Hernandez, Bernd Hinzmann, Sarah Ho, Michael Hoffs, Phillip J. Howden, Elizabeth J. Huckle, Jennifer Hume, Paul J. Hunt, Adrienne R. Hunt, Judith Isherwood, Leni Jacob, David Johnson, Sally Jones, Pieter J. de Jong, Shirin S. Joseph, Stephen Keenan, Susan Kelly, Joanne K. Kershaw, Ziad Khan, Petra Kioschis, Sven Klages, Andrew J. Knights, Anna Kosiura, Christie Kovar-Smith, Gavin K. Laird, Cordelia Langford, Stephanie Lawlor, Margaret Leversha, Lora Lewis, Wen Liu, Christine Lloyd, David M. Lloyd, Hermela Loulseged, Jane E. Loveland, Jamieson D. Lovell, Ryan Lozado, Jing Lu, Rachael Lyne, Jie Ma, Manjula Maheshwari, Lucy H. Matthews, Jennifer McDowall, Stuart McLaren, Amanda McMurray, Patrick Meidl, Thomas Meitinger, Sarah Milne, George Miner, Shailesh L. Mistry, Margaret Morgan, Sidney Morris, Ines Müller, James C. Mullikin, Ngoc Nguyen, Gabriele Nordsiek, Gerald Nyakatura, Christopher N. O’Dell, Geoffery Okwuonu, Sophie Palmer, Richard Pandian, David Parker, Julia Parrish, Shiran Pasternak, Dina Patel, Alex V. Pearce, Danita M. Pearson, Sarah E. Pelan, Lesette Perez, Keith M. Porter, Yvonne Ramsey, Kathrin Reichwald, Susan Rhodes, Kerry A. Ridler, David Schlessinger, Mary G. Schueler, Harminder K. Sehra, Charles Shaw-Smith, Hua Shen, Elizabeth M. Sheridan, Ratna Shownkeen, Carl D. Skuce, Michelle L. Smith, Elizabeth C. Sotheran, Helen E. Steingruber, Charles A. Steward, Roy Storey, R. Mark Swann, David Swarbreck, Paul E. Tabor, Stefan Taudien, Tineace Taylor, Brian Teague, Karen Thomas, Andrea Thorpe, Kirsten Timms, Alan Tracey, Steve Trevanion, Anthony C. Tromans, Michele d’Urso, Daniel Verduzco, Donna Villasana, Lenee Waldron, Melanie Wall, Qiaoyan Wang, James Warren, Georgina L. Warry, Xuehong Wei, Anthony West, Siobhan L. Whitehead, Mathew N. Whiteley, Jane E. Wilkinson, David L. Willey, Gabrielle Williams, Leanne Williams, Angela Williamson, Helen Williamson, Laurens Wilming, Rebecca L. Woodmansey, Paul W. Wray, Jennifer Yen, Jingkun Zhang, Jianling Zhou, Huda Zoghbi, Sara Zorilla, David Buck, Richard Reinhardt, Annemarie Poustka, André Rosenthal, Hans Lehrach, Alfons Meindl, Patrick J. Minx, LaDeana W. Hillier, Huntington F. Willard, Richard K. Wilson, Robert H. Waterston, Catherine M. Rice, Mark Vaudin, Alan Coulson, David L. Nelson, George Weinstock, John E. Sulston, Richard Durbin, Tim Hubbard, Richard A. Gibbs, Stephan Beck, Jane Rogers, David R. Bentley

Nature. Author manuscript; available in PMC 2009 Apr 5.

Published in final edited form as: Nature. 2005 Mar 17; 434(7031): 325–337. doi: 10.1038/nature03440

PMCID:: PMC2665286

Abstract Article PDF–1.0M

Select item 399653712.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650