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Select item 99569291.

An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling

Brian G. Hunt, Levi H. Fox, James C. Davis, Angelle Jones, Zhixin Lu, Susan E. Waltz

Genes (Basel) 2023 Feb; 14(2): 517. Published online 2023 Feb 17. doi: 10.3390/genes14020517

PMCID:: PMC9956929

Abstract Article PDF–668K

Select item 78759132.

Recepteur d'origine nantais contributes to the development of endometriosis via promoting epithelial‐mesenchymal transition of a endometrial epithelial cells

Qin Yu, Jianzhang Wang, Tiantian Li, Xinyue Guo, Shaojie Ding, Xuan Che, Libo Zhu, Yangying Peng, Xinxin Xu, Gen Zou, Xinmei Zhang

J Cell Mol Med. 2021 Feb; 25(3): 1601–1612. Published online 2021 Jan 6. doi: 10.1111/jcmm.16261

PMCID:: PMC7875913

Abstract Article PDF–3.6M

Select item 78510203.

Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer

Ziliang Wang, Yufei Yang, Shuang Hu, Jian He, Zheng Wu, Zihao Qi, Mingzhu Huang, Rujiao Liu, Ying Lin, Cong Tan, Midie Xu, Zhe Zhang

Cell Biol Toxicol. 2021; 37(1): 35–49. Published online 2020 May 12. doi: 10.1007/s10565-020-09525-5

PMCID:: PMC7851020

Abstract Article PDF–8.3M

Select item 77825014.

RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer

Derek Dustin, Guowei Gu, Amanda R. Beyer, Sarah K. Herzog, David G. Edwards, Hangqing Lin, Thomas L. Gonzalez, Sandra L. Grimm, Cristian Coarfa, Doug W. Chan, Beom-Jun Kim, Jean-Paul De La O, Matthew J. Ellis, Dan Liu, Shunqiang Li, Alana L. Welm, Suzanne A. W. Fuqua

Br J Cancer. 2021 Jan 5; 124(1): 191–206. Published online 2020 Dec 1. doi: 10.1038/s41416-020-01174-z

PMCID:: PMC7782501

Abstract Article PDF–1.4M

Select item 72558515.

MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients

Brian G Hunt, Christina A Wicker, Jennifer R Bourn, Elyse E Lower, Vinita Takiar, Susan E Waltz

Breast Cancer Res Treat. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Breast Cancer Res Treat. 2020 Jun; 181(3): 529–540. Published online 2020 Apr 27. doi: 10.1007/s10549-020-05653-y

PMCID:: PMC7255851

Abstract Article PDF–2.1M

Select item 65250176.

Receptor tyrosine kinase RON as predictive marker for aggressive prostate cancer in African Americans

Roble G Bedolla, Dimpy P. Shah, Shih-Bo Huang, Robert L Reddick, Rita Ghosh, Addanki P Kumar

Mol Carcinog. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Mol Carcinog. 2019 Jun; 58(6): 854–861. Published online 2019 Mar 11. doi: 10.1002/mc.23002

PMCID:: PMC6525017

Abstract Article PDF–2.0M

Select item 60982057.

Tumor Cell Autonomous RON Receptor Expression Promotes Prostate Cancer Growth Under Conditions of Androgen Deprivation

Nicholas E. Brown, Andrew M. Paluch, Madison A. Nashu, Kakajan Komurov, Susan E. Waltz

Neoplasia. 2018 Sep; 20(9): 917–929. Published online 2018 Aug 15. doi: 10.1016/j.neo.2018.07.003

PMCID:: PMC6098205

Abstract Article PDF–853K

Select item 60980998.

Decoding a cancer-relevant splicing decision in the RON proto-oncogene using high-throughput mutagenesis

Simon Braun, Mihaela Enculescu, Samarth T. Setty, Mariela Cortés-López, Bernardo P. de Almeida, F. X. Reymond Sutandy, Laura Schulz, Anke Busch, Markus Seiler, Stefanie Ebersberger, Nuno L. Barbosa-Morais, Stefan Legewie, Julian König, Kathi Zarnack

Nat Commun. 2018; 9: 3315. Published online 2018 Aug 17. doi: 10.1038/s41467-018-05748-7

PMCID:: PMC6098099

Abstract Article PDF–3.4M

Select item 55035989.

A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

Yu Ling, Yeye Kuang, Lin-Lin Chen, Wei-Feng Lao, Yao-Ru Zhu, Le-Qi Wang, Da Wang

Oncotarget. 2017 Jun 13; 8(24): 39101–39116. Published online 2017 Mar 27. doi: 10.18632/oncotarget.16603

PMCID:: PMC5503598

Abstract Article PDF–8.5M

Select item 535566910.

Monoclonal antibody Zt/g4 targeting RON receptor tyrosine kinase enhances chemosensitivity of bladder cancer cells to Epirubicin by promoting G1/S arrest and apoptosis

Jun-Feng Chen, Bi-Xia Yu, Rui Yu, Liang Ma, Xiu-Yi Lv, Yue Cheng, Qi Ma

Oncol Rep. 2017 Feb; 37(2): 721–728. Published online 2017 Jan 5. doi: 10.3892/or.2017.5356

PMCID:: PMC5355669

Abstract Article PDF–807K

Select item 531265811.

The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming

Stéphanie Cunha, Yi-Chun Lin, Elizabeth A. Goossen, Christa I. DeVette, Mark R. Albertella, Stuart Thomson, Mark J. Mulvihill, Alana L. Welm

Cell Rep. Author manuscript; available in PMC 2017 Feb 16.

Published in final edited form as: Cell Rep. 2014 Jan 16; 6(1): 141–154. Published online 2014 Jan 2. doi: 10.1016/j.celrep.2013.12.010

PMCID:: PMC5312658

Abstract Article PDF–4.1M

Select item 521677412.

Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics

Jeffery Chakedis, Randall French, Michele Babicky, Dawn Jaquish, Evangeline Mose, Peter Cheng, Patrick Holman, Haleigh Howard, Jaclyn Miyamoto, Paula Porras, Zakk Walterscheid, Carsten Schultz-Fademrecht, Christina Esdar, Oliver Schadt, Jan Eickhoff, Andrew M. Lowy

Oncotarget. 2016 Jul 19; 7(29): 45959–45975. Published online 2016 Jun 14. doi: 10.18632/oncotarget.10009

PMCID:: PMC5216774

Abstract Article PDF–8.8M

Select item 483710813.

A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells

Jeffery Chakedis, Randall French, Michele Babicky, Dawn Jaquish, Haleigh Howard, Evangeline Mose, Raymond Lam, Patrick Holman, Jaclyn Miyamoto, Zakk Walterscheid, Andrew M. Lowy

Oncogene. Author manuscript; available in PMC 2016 Jul 8.

Published in final edited form as: Oncogene. 2016 Jun 23; 35(25): 3249–3259. Published online 2015 Oct 19. doi: 10.1038/onc.2015.384

PMCID:: PMC4837108

Abstract Article PDF–1.5M

Select item 481276714.

Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma

Wei Dai, Hong Zheng, Arthur Kwok Leung Cheung, Clara Sze-man Tang, Josephine Mun Yee Ko, Bonnie Wing Yan Wong, Merrin Man Long Leong, Pak Chung Sham, Florence Cheung, Dora Lai-Wan Kwong, Roger Kai Cheong Ngan, Wai Tong Ng, Chun Chung Yau, Jianji Pan, Xun Peng, Stewart Tung, Zengfeng Zhang, Mingfang Ji, Alan Kwok-Shing Chiang, Anne Wing-Mui Lee, Victor Ho-fun Lee, Ka-On Lam, Kwok Hung Au, Hoi Ching Cheng, Harry Ho-Yin Yiu, Maria Li Lung

Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12): 3317–3322. Published online 2016 Mar 7. doi: 10.1073/pnas.1523436113

PMCID:: PMC4812767

Abstract Article PDF–1.5M

Select item 452830615.

A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene

HEEGYUM MOON, SUNGHEE CHO, TIING JEN LOH, JIANHUA ZHOU, CLAUDIA GHIGNA, GIUSEPPE BIAMONTI, MICHAEL R. GREEN, XUEXIU ZHENG, HAIHONG SHEN

Oncol Rep. 2014 Jan; 31(1): 450–455. Published online 2013 Nov 5. doi: 10.3892/or.2013.2835

PMCID:: PMC4528306

Abstract Article PDF–431K

Select item 429673316.

Human RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence

Marceline Côté, A. Dusty Miller, Shan-Lu Liu

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Jan 16.

Published in final edited form as: Biochem Biophys Res Commun. 2007 Aug 17; 360(1): 219–225. Published online 2007 Jun 18. doi: 10.1016/j.bbrc.2007.06.033

PMCID:: PMC4296733

Abstract Article PDF–1.9M

Select item 410243317.

Purnima Wagh, Belinda E. Peace, Susan E. Waltz

Adv Cancer Res. Author manuscript; available in PMC 2014 Jul 17.

Published in final edited form as: Adv Cancer Res. 2008; 100: 1–33. doi: 10.1016/S0065-230X(08)00001-8

PMCID:: PMC4102433

Abstract Article PDF–503K

Select item 400939518.

The RON Receptor Tyrosine Kinase in Pancreatic Cancer Pathogenesis and Its Potential Implications for Future Targeted Therapies

Chang Moo Kang, Michele L. Babicky, Andrew M. Lowy

Pancreas. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: Pancreas. 2014 Mar; 43(2): 183–189. doi: 10.1097/MPA.0000000000000088

PMCID:: PMC4009395

Abstract Article PDF–589K

Select item 379650519.

Intron Retention in the Alternatively Spliced Region of RON Results from Weak 3’ Splice Site Recognition

Lindsay D. Smith, Christian M. Lucas, Ian C. Eperon

PLoS One. 2013; 8(10): e77208. Published online 2013 Oct 14. doi: 10.1371/journal.pone.0077208

PMCID:: PMC3796505

Abstract Article PDF–1.6M

Select item 353218320.

RON is not a prognostic marker for resectable pancreatic cancer

Carole M Tactacan, David K Chang, Mark J Cowley, Emily S Humphrey, Jianmin Wu, Anthony J Gill, Angela Chou, Katia Nones, Sean M Grimmond, Robert L Sutherland, Andrew V Biankin, Roger J Daly

BMC Cancer. 2012; 12: 395. Published online 2012 Sep 7. doi: 10.1186/1471-2407-12-395

PMCID:: PMC3532183

Abstract Article PDF–1.9M

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