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Select item 113681741.

MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer

Beatriz German, Sarah A. Alaiwi, Kun-Lin Ho, Jagpreet S. Nanda, Marcos A. Fonseca, Deborah L. Burkhart, Anjali V. Sheahan, Hannah E. Bergom, Katherine L. Morel, Himisha Beltran, Justin H. Hwang, Matthew L. Freedman, Kate Lawrenson, Leigh Ellis

Cancer Res Commun. 2024 Sep; 4(9): 2295–2307. Published online 2024 Sep 2. doi: 10.1158/2767-9764.CRC-24-0069

PMCID:: PMC11368174

Abstract Article PDF–22M

Select item 113173012.

Single-cell RNA sequencing reveals that MYBL2 in malignant epithelial cells is involved in the development and progression of ovarian cancer

Wenwen Shao, Zhiheng Lin, Zhikai Xiahou, Fu Zhao, Jue Xu, Xinqi Liu, Pingping Cai

Front Immunol. 2024; 15: 1438198. Published online 2024 Jul 29. doi: 10.3389/fimmu.2024.1438198

PMCID:: PMC11317301

Abstract Article PDF–17M

Select item 111198633.

Ectopic MYBL2-Mediated Regulation of Androglobin Gene Expression

Antonia Herwig, Carina Osterhof, Anna Keppner, Darko Maric, Teng Wei Koay, Ambre Mbemba-Nsungi, David Hoogewijs

Cells. 2024 May; 13(10): 826. Published online 2024 May 11. doi: 10.3390/cells13100826

PMCID:: PMC11119863

Abstract Article PDF–2.3M

Select item 111151464.

B-MYB delays cell aging by repressing p16^INK4α transcription

Yu Huang, Junfeng Wu, Renzhong Li, Peichang Wang, Limin Han, Zongyu Zhang, Tanjun Tong

Cell Mol Life Sci. 2011 Mar; 68(5): 893–901. Published online 2010 Aug 25. doi: 10.1007/s00018-010-0501-9

PMCID:: PMC11115146

Abstract Article PDF–610K

Select item 94585355.

MYBL2在前列腺癌患者组织中高表达并与不良预后相关

杨明, 朱旭东, 沈炀, 何麒, 秦远, 邵轶群, 袁琳, 叶和松

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Aug 20; 42(8): 1109–1118. Chinese. doi: 10.12122/j.issn.1673-4254.2022.08.01

PMCID:: PMC9458535

Abstract Article PDF–2.5M

Select item 89738666.

MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression

Miao Liu, Qiang Du, Gang Mao, Ning Dai, Fan Zhang

Bioengineered. 2022; 13(3): 5344–5356. Published online 2022 Feb 17. doi: 10.1080/21655979.2021.2017630

PMCID:: PMC8973866

Abstract Article PDF–3.7M

Select item 87945277.

Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene

Xingjie Chen, Yalin Lu, Hao Yu, Kangjie Du, Yu Zhang, Yang Nan, Qiang Huang

Cell Cycle. 2021; 20(21): 2291–2308. Published online 2021 Sep 29. doi: 10.1080/15384101.2021.1982494

PMCID:: PMC8794527

Abstract Article PDF–6.0M

Select item 80545698.

Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu

Eur J Histochem. 2021 Mar 24; 65(2): 3226. Published online 2021 Mar 30. doi: 10.4081/ejh.2021.3226

PMCID:: PMC8054569

Abstract Article PDF–975K

Select item 68399539.

circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression

Yu-Meng Sun, Wen-Tao Wang, Zhan-Cheng Zeng, Tian-Qi Chen, Cai Han, Qi Pan, Wei Huang, Ke Fang, Lin-Yu Sun, Yan-Fei Zhou, Xue-Qun Luo, Chengwei Luo, Xin Du, Yue-Qin Chen

Blood. 2019 Oct 31; 134(18): 1533–1546. Prepublished online 2019 Aug 6. doi: 10.1182/blood.2019000802

PMCID:: PMC6839953

Abstract Article

Select item 617662410.

Structural mechanism of Myb–MuvB assembly

Keelan Z. Guiley, Audra N. Iness, Siddharth Saini, Sarvind Tripathi, Joseph S. Lipsick, Larisa Litovchick, Seth M. Rubin

Proc Natl Acad Sci U S A. 2018 Oct 2; 115(40): 10016–10021. Published online 2018 Sep 17. doi: 10.1073/pnas.1808136115

PMCID:: PMC6176624

Abstract Article PDF–1.4M

Select item 371345511.

MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy

Stefan Heinrichs, Lillian F Conover, Carlos E Bueso-Ramos, Outi Kilpivaara, Kristen Stevenson, Donna Neuberg, Mignon L Loh, Wen-Shu Wu, Scott J Rodig, Guillermo Garcia-Manero, Hagop M Kantarjian, A Thomas Look

eLife. 2013; 2: e00825. Published online 2013 Jul 16. doi: 10.7554/eLife.00825

PMCID:: PMC3713455

Abstract Article PDF–5.7M

Select item 350750012.

B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1)

Eugen Werwein, Thore Schmedt, Heiko Hoffmann, Clemens Usadel, Nora Obermann, Jeffrey D. Singer, Karl-Heinz Klempnauer

Cell Cycle. 2012 Nov 1; 11(21): 4047–4058. doi: 10.4161/cc.22386

PMCID:: PMC3507500

Abstract Article PDF–1.5M

Select item 301274313.

MYBL2, A LINK BETWEEN PROLIFERATION AND DIFFERENTIATION IN MATURING COLON EPITHELIAL CELLS

Michael Papetti, Leonard H. Augenlicht

J Cell Physiol. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: J Cell Physiol. 2011 Mar; 226(3): 785–791. doi: 10.1002/jcp.22399

PMCID:: PMC3012743

Abstract Article PDF–1.0M

Select item 263685214.

In Vitro and In Vivo Analysis of B-Myb in Basal-Like Breast Cancer

AR Thorner, KA Hoadley, JS Parker, S Winkel, RC Millikan, CM Perou

Oncogene. Author manuscript; available in PMC 2009 Aug 5.

Published in final edited form as: Oncogene. 2009 Feb 5; 28(5): 742–751. Published online 2008 Dec 1. doi: 10.1038/onc.2008.430

PMCID:: PMC2636852

Abstract Article PDF–715K

Select item 5588915.

The highly conserved DNA-binding domains of A-, B- and c-Myb differ with respect to DNA-binding, phosphorylation and redox properties

Stine Bergholtz, Tor Øyvind Andersen, Kristin B. Andersson, Jørgen Borrebæk, Bernhard Lüscher, Odd S. Gabrielsen

Nucleic Acids Res. 2001 Sep 1; 29(17): 3546–3556. doi: 10.1093/nar/29.17.3546

PMCID:: PMC55889

Abstract Article PDF–448K

Select item 1113668216.

CircMYBL2 facilitates hepatocellular carcinoma progression by regulating E2F1 expression

JUNZHE YI, BINBIN LI, XIAOMIN YIN, LINGRUI LIU, CAILU SONG, YING ZHAO, MANBO CAI, HAILIN TANG, DONG CHEN, NING LYU

Oncol Res. 2024; 32(6): 1129–1139. Published online 2024 May 23. doi: 10.32604/or.2024.047524

PMCID:: PMC11136682

Abstract Article PDF–7.5M

Select item 973302317.

MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Jun-Zhang Zhao, Wei Wang, Tao Liu, Lei Zhang, De-Zheng Lin, Jia-Yin Yao, Xiang Peng, Gang Jin, Tian-Tian Ma, Jin-Bo Gao, Fang Huang, Jun Nie, Qing Lv

BMC Cancer. 2022; 22: 1290. Published online 2022 Dec 9. doi: 10.1186/s12885-022-10354-4

PMCID:: PMC9733023

Abstract Article PDF–8.8M

Select item 916202818.

Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cells

Jie Li, Hui Chen

Bioengineered. 2022; 13(4): 9019–9031. Published online 2022 Mar 28. doi: 10.1080/21655979.2022.2056821

PMCID:: PMC9162028

Abstract Article PDF–4.7M

Select item 844582119.

B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2

Xiaoyan Fan, Yitao Wang, Tinghui Jiang, Tao Liu, Yuelei Jin, Kailong Du, Yulong Niu, Chunxue Zhang, Zhongyu Liu, Yunlong Lei, Youquan Bu

Oncogene. 2021; 40(37): 5613–5625. Published online 2021 Jul 27. doi: 10.1038/s41388-021-01961-9

PMCID:: PMC8445821

Abstract Article PDF–5.8M

Select item 805871420.

MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer

Qiji Li, Min Wang, Yanqing Hu, Ensi Zhao, Jun Li, Liangliang Ren, Meng Wang, Yuandong Xu, Qian Liang, Di Zhang, Yingrong Lai, Shaoyu Liu, Xinsheng Peng, Chengming Zhu, Liping Ye

Theranostics. 2021; 11(12): 5794–5812. Published online 2021 Mar 31. doi: 10.7150/thno.56604