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Select item 102503971.

SERCA2 phosphorylation at serine 663 is a key regulator of Ca²⁺ homeostasis in heart diseases

Fabrice Gonnot, Laura Boulogne, Camille Brun, Maya Dia, Yves Gouriou, Gabriel Bidaux, Christophe Chouabe, Claire Crola Da Silva, Sylvie Ducreux, Bruno Pillot, Andrea Kaczmarczyk, Christelle Leon, Stephanie Chanon, Coralie Perret, Franck Sciandra, Tanushri Dargar, Vincent Gache, Fadi Farhat, Laurent Sebbag, Thomas Bochaton, Helene Thibault, Michel Ovize, Melanie Paillard, Ludovic Gomez

Nat Commun. 2023; 14: 3346. Published online 2023 Jun 8. doi: 10.1038/s41467-023-39027-x

PMCID:: PMC10250397

Abstract Article PDF–3.0M

Select item 101932582.

Association of Somatic ATP2A2 Damaging Variants With Grover Disease

Devin Seli, Katharine T. Ellis, Mohamad Goldust, Khadim Shah, Ronghua Hu, Jing Zhou, Jennifer M. McNiff, Keith A. Choate

JAMA Dermatol. 2023 Jul; 159(7): 745–749. Published online 2023 May 17. doi: 10.1001/jamadermatol.2023.1139

PMCID:: PMC10193258

Abstract Article

Select item 75679873.

Dimerization of SERCA2a Enhances Transport Rate and Improves Energetic Efficiency in Living Cells

Elisa Bovo, Roman Nikolaienko, Sean R. Cleary, Jaroslava Seflova, Daniel Kahn, Seth L. Robia, Aleksey V. Zima

Biophys J. 2020 Oct 6; 119(7): 1456–1465. Published online 2020 Aug 28. doi: 10.1016/j.bpj.2020.08.025

PMCID:: PMC7567987

Abstract Article PDF–1.1M

Select item 74141644.

What ATP binding does to the Ca²⁺ pump and how nonproductive phosphoryl transfer is prevented in the absence of Ca²⁺

Yoshiki Kabashima, Haruo Ogawa, Rie Nakajima, Chikashi Toyoshima

Proc Natl Acad Sci U S A. 2020 Aug 4; 117(31): 18448–18458. Published online 2020 Jul 16. doi: 10.1073/pnas.2006027117

PMCID:: PMC7414164

Abstract Article PDF–5.0M

Select item 60092815.

Sarco(endo)plasmic Reticulum Ca-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene

Angel Zarain-Herzberg, Georgina Alvarez-Fernandez

ScientificWorldJournal. 2002; 2: 1469–1483. Published online 2002 May 29. doi: 10.1100/tsw.2002.228

PMCID:: PMC6009281

Abstract PDF–1.3M

Select item 59347656.

Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation

Cristine Betzer, Louise Berkhoudt Lassen, Anders Olsen, Rikke Hahn Kofoed, Lasse Reimer, Emil Gregersen, Jin Zheng, Tito Calì, Wei‐Ping Gai, Tong Chen, Arne Moeller, Marisa Brini, Yuhong Fu, Glenda Halliday, Tomasz Brudek, Susana Aznar, Bente Pakkenberg, Jens Peter Andersen, Poul Henning Jensen

EMBO Rep. 2018 May; 19(5): e44617. Published online 2018 Mar 29. doi: 10.15252/embr.201744617

PMCID:: PMC5934765

Abstract Article PDF–2.0M

Select item 58579817.

Skin cells prefer a slower calcium pump

Seth L. Robia, Howard S. Young

J Biol Chem. 2018 Mar 16; 293(11): 3890–3891. doi: 10.1074/jbc.H118.002088

PMCID:: PMC5857981

Abstract Article PDF–96K

Select item 58579738.

A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca²⁺-ATPase 2b

Stine A. Mikkelsen, Peter Vangheluwe, Jens Peter Andersen

J Biol Chem. 2018 Mar 16; 293(11): 3880–3889. Published online 2018 Jan 23. doi: 10.1074/jbc.RA117.000941

PMCID:: PMC5857973

Abstract Article PDF–1.5M

Select item 56402449.

Novel mutations in Darier disease and association to self-reported disease severity

Ivone U. S. Leong, Alexander Stuckey, Tara Ahanian, Martin Cederlöf, Jakob D. Wikstrom

PLoS One. 2017; 12(10): e0186356. Published online 2017 Oct 13. doi: 10.1371/journal.pone.0186356

PMCID:: PMC5640244

Abstract Article PDF–2.6M

Select item 538425510.

ER-to-Golgi Blockade of Nascent Desmosomal Cadherins in SERCA2-inhibited Keratinocytes: Implications for Darier’s Disease

Ning Li, Moonhee Park, Shengxiang Xiao, Zhi Liu, Luis A. Diaz

Traffic. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Traffic. 2017 Apr; 18(4): 232–241. Published online 2017 Feb 28. doi: 10.1111/tra.12470

PMCID:: PMC5384255

Abstract Article PDF–2.1M

Select item 474195211.

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer

Baofang Yang, Minxia Zhang, Jian Gao, Jiahuang Li, Lu Fan, Gang Xiang, Xingqi Wang, Xiaoning Wang, Xuefeng Wu, Yang Sun, Xudong Wu, Guang Liang, Yan Shen, Qiang Xu

Oncotarget. 2015 Nov 10; 6(35): 37613–37625. Published online 2015 Oct 10. doi: 10.18632/oncotarget.6068

PMCID:: PMC4741952

Abstract Article PDF–7.5M

Select item 446409212.

Identification of two novel Darier disease-associated mutations in the ATP2A2 gene

LIBAO ZHENG, HUILI JIANG, QIN MEI, BIN CHEN

Mol Med Rep. 2015 Aug; 12(2): 1845–1849. Published online 2015 Apr 9. doi: 10.3892/mmr.2015.3605

PMCID:: PMC4464092

Abstract Article PDF–837K

Select item 434947713.

No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma

David Sweeney, Fay Hollins, Edith Gomez, Rajendra Mistry, Ruth Saunders, Robert Alfred John Challiss, Christopher Edward Brightling

BMC Pulm Med. 2015; 15: 12. Published online 2015 Feb 13. doi: 10.1186/s12890-015-0009-z

PMCID:: PMC4349477

Abstract Article PDF–1.3M

Select item 353218114.

MicroRNAs and cardiac sarcoplasmic reticulum calcium ATPase-2 in human myocardial infarction: expression and bioinformatic analysis

Emanuela Boštjančič, Nina Zidar, Damjan Glavač

BMC Genomics. 2012; 13: 552. Published online 2012 Oct 15. doi: 10.1186/1471-2164-13-552

PMCID:: PMC3532181

Abstract Article PDF–715K

Select item 350102415.

Distinct Roles of the C-terminal 11th Transmembrane Helix and Luminal Extension in the Partial Reactions Determining the High Ca²⁺ Affinity of Sarco(endo)plasmic Reticulum Ca²⁺-ATPase Isoform 2b (SERCA2b)

Johannes D. Clausen, Ilse Vandecaetsbeek, Frank Wuytack, Peter Vangheluwe, Jens Peter Andersen

J Biol Chem. 2012 Nov 16; 287(47): 39460–39469. Published online 2012 Sep 28. doi: 10.1074/jbc.M112.397331

PMCID:: PMC3501024

Abstract Article PDF–2.5M

Select item 330585016.

SERCA2-controlled Ca²⁺-dependent Keratinocyte Adhesion and Differentiation is Mediated via the Sphingolipid Pathway- a Novel Therapeutic Target for Darier’s Disease

Anna Celli, Donald S. Mackenzie, Yongjiao Zhai, Chia-Ling Tu, Daniel Bikle, Walter Holleran, Yoshikazu Uchida, Theodora Mauro

J Invest Dermatol. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: J Invest Dermatol. 2012 Apr; 132(4): 1188–1195. Published online 2012 Jan 26. doi: 10.1038/jid.2011.447

PMCID:: PMC3305850

Abstract Article PDF–1.4M

Select item 326536917.

A segmental genomic duplication generates a functional intron

Uffe Hellsten, Julie L. Aspden, Donald C. Rio, Daniel S. Rokhsar

Nat Commun. 2011 Aug 30; 2: 454. Published online 2011 Aug 30. doi: 10.1038/ncomms1461

PMCID:: PMC3265369

Abstract Article PDF–431K

Select item 321405718.

SERCA2 Regulates Non-CF and CF Airway Epithelial Cell Response to Ozone

Shama Ahmad, David P. Nichols, Matthew Strand, Raymond C. Rancourt, Scott H. Randell, Carl W. White, Aftab Ahmad

PLoS One. 2011; 6(11): e27451. Published online 2011 Nov 11. doi: 10.1371/journal.pone.0027451

PMCID:: PMC3214057

Abstract Article PDF–1.2M

Select item 313882219.

Enhanced ER Ca²⁺ store filling by overexpression of SERCA2b promotes IP₃-evoked puffs

Michiko Yamasaki-Mannand, Ian Parker

Cell Calcium. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Cell Calcium. 2011 Jul; 50(1): 36–41. Published online 2011 May 26. doi: 10.1016/j.ceca.2011.04.008

PMCID:: PMC3138822

Abstract Article PDF–752K

Select item 312151920.

Highly Cooperative Dependence of Sarco/Endoplasmic Reticulum Calcium ATPase (SERCA) 2a Pump Activity on Cytosolic Calcium in Living Cells

Kanayo Satoh, Toru Matsu-ura, Masahiro Enomoto, Hideki Nakamura, Takayuki Michikawa, Katsuhiko Mikoshiba

J Biol Chem. 2011 Jun 10; 286(23): 20591–20599. Published online 2011 Apr 22. doi: 10.1074/jbc.M110.204685

PMCID:: PMC3121519

Abstract Article PDF–2.6M

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