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Items: 1 to 20 of 310

1.
Changes in cell morphology and function induced by the NRAS Q61R mutation in lymphatic endothelial cells
Shiho Yasue, Michio Ozeki, Akifumi Nozawa, Saori Endo, Hidenori Ohnishi
PLoS One. 2024; 19(5): e0289187. Published online 2024 May 29. doi: 10.1371/journal.pone.0289187
PMCID:
PMC11135733
AbstractArticlePDF–2.1M
2.
Missense mutation of NRAS is associated with malignant progression in neurocutaneous melanosis
Haruhiko Takahashi, Manabu Natsumeda, Norikazu Hara, Akihide Koyama, Hiroshi Shimizu, Akinori Miyashita, Daiken Satake, Yoshihiro Mouri, Jun Tsukano, Keita Kawabe, Yoshihiro Tsukamoto, Masayasu Okada, Ryosuke Ogura, Akihiko Yuki, Hajime Umezu, Akiyoshi Kakita, Takeshi Ikeuchi, Makoto Oishi
Acta Neuropathol Commun. 2024; 12: 14. Published online 2024 Jan 22. doi: 10.1186/s40478-024-01723-0
PMCID:
PMC10804483
AbstractArticlePDF–6.0M
3.
NRASQ61R mutation in human endothelial cells causes vascular malformations
Elisa Boscolo, Patricia Pastura, Sandra Schrenk, Jillian Goines, Rachael Kang, Devin Pillis, Punam Malik, Timothy D. Le Cras
Angiogenesis. Author manuscript; available in PMC 2022 Nov 3.
Published in final edited form as: Angiogenesis. 2022 Aug; 25(3): 331–342. Published online 2022 Apr 7. doi: 10.1007/s10456-022-09836-7
PMCID:
PMC9631803
AbstractArticlePDF–2.0M
4.
Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness
Ze-Yi Zheng, Hanan Elsarraj, Jonathan T. Lei, Yan Hong, Meenakshi Anurag, Long Feng, Hilda Kennedy, Yichao Shen, Flora Lo, Zifan Zhao, Bing Zhang, Xiang H.-F. Zhang, Ossama W. Tawfik, Fariba Behbod, Eric C. Chang
Breast Cancer Res. 2022; 24: 68. Published online 2022 Oct 18. doi: 10.1186/s13058-022-01565-5
PMCID:
PMC9578182
AbstractArticlePDF–5.6M
5.
The frequency and clinicopathological significance of NRAS mutations in primary cutaneous nodular melanoma in Indonesia
Hanggoro Tri Rinonce, Deflen Jumatul Sastri, Fita Trisnawati, Bidari Kameswari, Paranita Ferronika, Irianiwati
Cancer Rep (Hoboken) 2022 Jan; 5(1): e1454. Published online 2021 Jun 10. doi: 10.1002/cnr2.1454
PMCID:
PMC8789608
AbstractArticlePDF–1.4M
6.
Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family
Kevin M. Brown, Mai Xu, Michael Sargen, Hyunbum Jang, Mingzhen Zhang, Tongwu Zhang, Bin Zhu, Kristie Jones, Jung Kim, Laura Mendoza, Nicholas K. Hayward, Margaret A. Tucker, Alisa M. Goldstein, Xiaohong Rose Yang, Douglas R. Stewart, Belynda Hicks, Dario Consonni, Angela C. Pesatori, Maria Concetta Fargnoli, Ketty Peris, Alex Stratigos, Chiara Menin, Paola Ghiorzo, Susana Puig, Eduardo Nagore, MelaNostrum Consortium, Thorkell Andresson, Ruth Nussinov, Donato Calista, Maria Teresa Landi
Fam Cancer. Author manuscript; available in PMC 2023 Jul 1.
Published in final edited form as: Fam Cancer. 2022 Jul; 21(3): 347–355. Published online 2021 Jul 3. doi: 10.1007/s10689-021-00267-9
PMCID:
PMC8720902
AbstractArticlePDF–1.3M
7.
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy
Christopher J. Terranova, Ming Tang, Mayinuer Maitituoheti, Ayush T. Raman, Archit K. Ghosh, Jonathan Schulz, Samir B. Amin, Elias Orouji, Katarzyna Tomczak, Sharmistha Sarkar, Junna Oba, Caitlin Creasy, Chang-Jiun Wu, Samia Khan, Rossana Lazcano, Khalida Wani, Anand Singh, Praveen Barrodia, Dongyu Zhao, Kaifu Chen, Lauren E. Haydu, Wei-Lien Wang, Alexander J. Lazar, Scott E. Woodman, Chantale Bernatchez, Kunal Rai
Cell Rep. Author manuscript; available in PMC 2021 Aug 17.
Published in final edited form as: Cell Rep. 2021 Jul 20; 36(3): 109410. doi: 10.1016/j.celrep.2021.109410
PMCID:
PMC8369408
AbstractArticlePDF–3.0M
8.
Association of NRAS Mutation With Clinical Outcomes of Anti-PD-1 Monotherapy in Advanced Melanoma: A Pooled Analysis of Four Asian Clinical Trials
Li Zhou, Xuan Wang, Zhihong Chi, Xinan Sheng, Yan Kong, Lili Mao, Bin Lian, Bixia Tang, Xieqiao Yan, Xue Bai, Siming Li, Jun Guo, Chuanliang Cui, Lu Si
Front Immunol. 2021; 12: 691032. Published online 2021 Jul 5. doi: 10.3389/fimmu.2021.691032
PMCID:
PMC8289467
AbstractArticlePDF–829K
9.
Mutational spectrum and prognosis in NRAS-mutated acute myeloid leukemia
Shujuan Wang, Zhenzhen Wu, Tao Li, Yafei Li, Weiqiong Wang, Qianqian Hao, Xinsheng Xie, Dingming Wan, Zhongxing Jiang, Chong Wang, Yanfang Liu
Sci Rep. 2020; 10: 12152. Published online 2020 Jul 22. doi: 10.1038/s41598-020-69194-6
PMCID:
PMC7376066
AbstractArticlePDF–1.8M
10.
NRAS mutant E132K identified in young-onset sporadic colorectal cancer and the canonical mutants G12D and Q61K affect distinct oncogenic phenotypes
Ryan Timothy D. Yu, Reynaldo L. Garcia
Sci Rep. 2020; 10: 11028. Published online 2020 Jul 3. doi: 10.1038/s41598-020-67796-8
PMCID:
PMC7334206
AbstractArticlePDF–4.1M
11.
NRAS mRNA is differentially spliced to give five distinct isoforms: implications for melanoma therapy
Megan C Duggan, Kelly Regan, Gonzalo N Olaverria Salavaggione, J. Harrison Howard, Andrew R Stiff, Julia Sabella, Nicholas Latchana, Joseph Markowitz, Alejandro Gru, Susheela Tridandapani, Ann-Kathrin Eisfeld, Albert de la Chapelle, William E Carson, III
Melanoma Res. Author manuscript; available in PMC 2020 Mar 23.
Published in final edited form as: Melanoma Res. 2019 Oct; 29(5): 491–500. doi: 10.1097/CMR.0000000000000623
PMCID:
PMC7088457
AbstractArticlePDF–1.5M
12.
Mutations of RAS genes in endometrial polyps
Takashi Takeda, Kouji Banno, Yusuke Kobayashi, Masataka Adachi, Megumi Yanokura, Eiichiro Tominaga, Kenjiro Kosaki, Daisuke Aoki
Oncol Rep. 2019 Dec; 42(6): 2303–2308. Published online 2019 Oct 4. doi: 10.3892/or.2019.7353
PMCID:
PMC6826305
AbstractArticlePDF–489K
13.
Detection of NRAS mutation in cell-free DNA biological fluids from patients with kaposiform lymphangiomatosis
Michio Ozeki, Yoko Aoki, Akifumi Nozawa, Shiho Yasue, Saori Endo, Yumiko Hori, Kentaro Matsuoka, Tetsuya Niihori, Ryo Funayama, Matsuyuki Shirota, Keiko Nakayama, Toshiyuki Fukao
Orphanet J Rare Dis. 2019; 14: 215. Published online 2019 Sep 11. doi: 10.1186/s13023-019-1191-5
PMCID:
PMC6737666
AbstractArticlePDF–3.1M
14.
A Somatic Activating NRAS Variant Associated with Kaposiform Lymphangiomatosis
Sarah F. Barclay, Kyle W. Inman, Valerie L. Luks, John B. McIntyre, Alyaa Al-Ibraheemi, Alanna J. Church, Antonio R. Perez-Atayde, Shamlal Mangray, Michael Jeng, Sara R. Kreimer, Lori Walker, Steven J. Fishman, Ahmad I. Alomari, Gulraiz Chaudry, Cameron C. Trenor, III, Denise Adams, Harry P.W. Kozakewich, Kyle C. Kurek
Genet Med. Author manuscript; available in PMC 2019 Jun 14.
Published in final edited form as: Genet Med. 2019 Jul; 21(7): 1517–1524. Published online 2018 Dec 13. doi: 10.1038/s41436-018-0390-0
PMCID:
PMC6565516
AbstractArticlePDF–398K
15.
Prognostic Value of NRAS Gene for Survival of Colorectal Cancer Patients: A Systematic Review and Meta-Analysis
Yue Hu, Shuang-You Tao, Jie-Min Deng, Zheng-Kun Hou, Jia-Qi Liang, Qiu-Gu Huang, Liang-Hui Li, Hui-Biao Li, Yi-Ming Chen, Hua Yi, Xin-Lin Chen, Hui Liu
Asian Pac J Cancer Prev. 2018; 19(11): 3001–3008. doi: 10.31557/APJCP.2018.19.11.3001
PMCID:
PMC6318417
AbstractArticlePDF–496K
16.
bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling
Fereshteh Haghighi, Julia Dahlmann, Saeideh Nakhaei-Rad, Alexander Lang, Ingo Kutschka, Martin Zenker, George Kensah, Roland P. Piekorz, Mohammad Reza Ahmadian
Cell Commun Signal. 2018; 16: 96. Published online 2018 Dec 5. doi: 10.1186/s12964-018-0307-1
PMCID:
PMC6282345
AbstractArticlePDF–4.8M
17.
Clinical features and outcomes of patients with colorectal cancers harboring NRAS mutations
Andrea Cercek, Maria Ignez Braghiroli, Joanne F. Chou, Jaclyn F. Hechtman, Nancy Kemeny, Leonard Saltz, Marinela Capanu, Rona Yaeger
Clin Cancer Res. Author manuscript; available in PMC 2018 Aug 15.
Published in final edited form as: Clin Cancer Res. 2017 Aug 15; 23(16): 4753–4760. Published online 2017 Apr 26. doi: 10.1158/1078-0432.CCR-17-0400
PMCID:
PMC5788017
AbstractArticlePDF–395K
18.
Mutation of NRAS is a Rare Genetic Event in Ovarian Low-Grade Serous Carcinoma
Deyin Xing, Yohan Suryo Rahmanto, Felix Zeppernick, Charlotte G. Hannibal, Susanne K. Kjaer, Russell Vang, Ie-Ming Shih, Tian-Li Wang
Hum Pathol. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Hum Pathol. 2017 Oct; 68: 87–91. Published online 2017 Sep 2. doi: 10.1016/j.humpath.2017.08.021
PMCID:
PMC5696063
AbstractArticlePDF–501K
19.
Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care
Markus V. Heppt, Timo Siepmann, Jutta Engel, Gabriele Schubert-Fritschle, Renate Eckel, Laura Mirlach, Thomas Kirchner, Andreas Jung, Anja Gesierich, Thomas Ruzicka, Michael J. Flaig, Carola Berking
BMC Cancer. 2017; 17: 536. Published online 2017 Aug 10. doi: 10.1186/s12885-017-3529-5
PMCID:
PMC5553744
AbstractArticlePDF–609K
20.
Genotype and phenotype spectrum of NRAS germline variants
Franziska Altmüller, Christina Lissewski, Debora Bertola, Elisabetta Flex, Zornitza Stark, Stephanie Spranger, Gareth Baynam, Michelle Buscarilli, Sarah Dyack, Jane Gillis, Helger G Yntema, Francesca Pantaleoni, Rosa LE van Loon, Sara MacKay, Kym Mina, Ina Schanze, Tiong Yang Tan, Maie Walsh, Susan M White, Marena R Niewisch, Sixto García-Miñaúr, Diego Plaza, Mohammad Reza Ahmadian, Hélène Cavé, Marco Tartaglia, Martin Zenker
Eur J Hum Genet. 2017 Jul; 25(7): 823–831. Published online 2017 May 3. doi: 10.1038/ejhg.2017.65
PMCID:
PMC5520077
AbstractArticlePDF–942K

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