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Select item 63267971.

Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway

Takuto Nogimori, Kyutatsu Nishiura, Sho Kawashima, Takahiro Nagai, Yuka Oishi, Nao Hosoda, Hiroaki Imataka, Yoshiaki Kitamura, Yukio Kitade, Shin-ichi Hoshino

Nucleic Acids Res. 2019 Jan 10; 47(1): 432–449. Published online 2018 Nov 5. doi: 10.1093/nar/gky1087

PMCID:: PMC6326797

Abstract Article PDF–8.2M

Select item 61053772.

Identified OAS3 gene variants associated with coexistence of HBsAg and anti-HBs in chronic HBV infection

Sa Wang, Jing Wang, Mengjie Fan, Tengyan Li, Hong Pan, Xi Wang, Hankui Liu, Qiongfen Lin, Jianguo Zhang, Liping Guan, Daria V. Zhernakova, Stephen J. O'Brien, Zhenru Feng, Le Chang, Erhei Dai, Jianhua Lu, Hongli Xi, Zheng Zeng, Yanyan Yu, Binbin Wang

J Viral Hepat. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Viral Hepat. 2018 Aug; 25(8): 904–910. Published online 2018 May 29. doi: 10.1111/jvh.12899

PMCID:: PMC6105377

Abstract Article PDF–1.0M

Select item 43602103.

Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk

G P Sava, H E Speedy, M C Di Bernardo, M J S Dyer, A Holroyd, N J Sunter, H Marr, L Mansouri, S Deaglio, L Karabon, I Frydecka, K Jamroziak, D Woszczyk, G Juliusson, K E Smedby, S Jayne, A Majid, Y Wang, C Dearden, A G Hall, T Mainou-Fowler, G H Jackson, G Summerfield, R J Harris, A R Pettitt, D J Allsup, J R Bailey, G Pratt, C Pepper, C Fegan, R Rosenquist, D Catovsky, J M Allan, R S Houlston

Leukemia. 2015 Mar; 29(3): 748–751. Prepublished online 2014 Nov 3. Published online 2014 Dec 5. doi: 10.1038/leu.2014.311

PMCID:: PMC4360210

Article PDF–505K

Select item 81792024.

Zika virus employs the host antiviral RNase L protein to support replication factory assembly

Jillian N. Whelan, Nicholas A. Parenti, Joshua Hatterschide, David M. Renner, Yize Li, Hanako M. Reyes, Beihua Dong, Erick R. Perez, Robert H. Silverman, Susan R. Weiss

Proc Natl Acad Sci U S A. 2021 Jun 1; 118(22): e2101713118. Published online 2021 May 24. doi: 10.1073/pnas.2101713118

PMCID:: PMC8179202

Abstract Article PDF–2.9M

Select item 64433285.

OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages

Wook-Bin Lee, Won Young Choi, Dong-Hyun Lee, Hyeran Shim, Jeongsil Kim-Ha, Young-Joon Kim

BMB Rep. 2019 Feb; 52(2): 133–138. Published online 2019 Feb 28. doi: 10.5483/BMBRep.2019.52.2.129

PMCID:: PMC6443328

Abstract Article PDF–1.9M

Select item 47764616.

Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

Yize Li, Shuvojit Banerjee, Yuyan Wang, Stephen A. Goldstein, Beihua Dong, Christina Gaughan, Robert H. Silverman, Susan R. Weiss

Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2241–2246. Published online 2016 Feb 8. doi: 10.1073/pnas.1519657113

Correction in:: Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12573.

PMCID:: PMC4776461

Abstract Article PDF–1.0M

Select item 98591397.

Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection

Sonam Gupta, Prithvi Singh, Alvea Tasneem, Ahmad Almatroudi, Arshad Husain Rahmani, Ravins Dohare, Shama Parveen

Genes (Basel) 2023 Jan; 14(1): 42. Published online 2022 Dec 23. doi: 10.3390/genes14010042

PMCID:: PMC9859139

Abstract Article PDF–3.7M

Select item 95831198.

IFN-β1b induces OAS3 to inhibit EV71 via IFN-β1b/JAK/STAT1 pathway

Baisong Zheng, Xiaolei Zhou, Li Tian, Jian Wang, Wenyan Zhang

Virol Sin. 2022 Oct; 37(5): 676–684. Published online 2022 Aug 5. doi: 10.1016/j.virs.2022.07.013

PMCID:: PMC9583119

Abstract Article PDF–2.3M

Select item 76931199.

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19

Hibah Shaath, Radhakrishnan Vishnubalaji, Eyad Elkord, Nehad M. Alajez

Cells. 2020 Nov; 9(11): 2374. Published online 2020 Oct 29. doi: 10.3390/cells9112374

PMCID:: PMC7693119

Abstract Article PDF–6.0M

Select item 673585210.

The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides

Valerie Odon, Jelke J Fros, Niluka Goonawardane, Isabelle Dietrich, Ahmad Ibrahim, Kinda Alshaikhahmed, Dung Nguyen, Peter Simmonds

Nucleic Acids Res. 2019 Sep 5; 47(15): 8061–8083. Published online 2019 Jul 5. doi: 10.1093/nar/gkz581

PMCID:: PMC6735852

Abstract Article PDF–16M

Select item 539469311.

Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production

Yun Yang, Shaoquan Xiong, Bei Cai, Hui Luo, E. Dong, Qiqi Li, Gaili Ji, Chengjian Zhao, Yanjun Wen, Yuquan Wei, Hanshuo Yang

Sci Rep. 2017; 7: 44303. Published online 2017 Apr 18. doi: 10.1038/srep44303

PMCID:: PMC5394693

Abstract Article PDF–1.7M

Select item 512924912.

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans

Aaron J. Sams, Anne Dumaine, Yohann Nédélec, Vania Yotova, Carolina Alfieri, Jerome E. Tanner, Philipp W. Messer, Luis B. Barreiro

Genome Biol. 2016; 17: 246. Published online 2016 Nov 29. doi: 10.1186/s13059-016-1098-6

PMCID:: PMC5129249

Abstract Article PDF–1.3M

Select item 424913313.

The 2′-5′-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2′-5′-Oligoadenylates Required for RNase L Activation

Mikkel Søes Ibsen, Hans Henrik Gad, Karthiga Thavachelvam, Thomas Boesen, Philippe Desprès, Rune Hartmann

J Virol. 2014 Dec; 88(24): 14222–14231. doi: 10.1128/JVI.01763-14

PMCID:: PMC4249133

Abstract Article PDF–1.9M

Select item 256462714.

Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?

M‐C Tessier, H‐Q Qu, R Fréchette, F Bacot, R Grabs, S P Taback, M L Lawson, S E Kirsch, T J Hudson, C Polychronakos

J Med Genet. 2006 Feb; 43(2): 129–132. Published online 2005 Jul 13. doi: 10.1136/jmg.2005.035212

PMCID:: PMC2564627

Abstract Article PDF–272K

Select item 55392915.

Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies.

A G Hovanessian, A G Laurent, J Chebath, J Galabru, N Robert, J Svab

EMBO J. 1987 May; 6(5): 1273–1280. doi: 10.1002/j.1460-2075.1987.tb02364.x

PMCID:: PMC553929

Summary Page Browse PDF–1.8M

Select item 357813116.

Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network

S Aslibekyan, P An, AC Frazier-Wood, EK Kabagambe, MR Irvin, RJ Straka, HK Tiwari, MY Tsai, PN Hopkins, IB Borecki, JM Ordovas, DK Arnett

Nutr Metab Cardiovasc Dis. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Nutr Metab Cardiovasc Dis. 2013 Oct; 23(10): 10.1016/j.numecd.2012.07.010. Published online 2012 Nov 11. doi: 10.1016/j.numecd.2012.07.010

PMCID:: PMC3578131

Abstract Article PDF–548K

Select item 295089817.

Dengue hemorrhagic fever is associated with polymorphisms in JAK1

Luciano K Silva, Ronald E Blanton, Antonio R Parrado, Paulo S Melo, Vanessa G Morato, Eliana AG Reis, Juarez P Dias, Jesuina M Castro, Pedro FC Vasconcelos, Katrina AB Goddard, Maurício L Barreto, Mitermayer G Reis, M Glória Teixeira

Eur J Hum Genet. 2010 Nov; 18(11): 1221–1227. Published online 2010 Jun 30. doi: 10.1038/ejhg.2010.98

PMCID:: PMC2950898

Abstract Article PDF–446K

Select item 387065918.

HIV-1 gp120 impairs B cell proliferation by inducing TGF-ß1 production and FcRL4 expression

Katija Jelicic, Raffaello Cimbro, Fatima Nawaz, Da Wei Huang, Xin Zheng, Jun Yang, Richard A. Lempicki, Massimiliano Pascuccio, Donald Van Ryk, Catherine Schwing, Joseph Hiatt, Noreen Okwara, Danlan Wei, Gregg Roby, Antonio David, Young Hwang, II, John H. Kehrl, James Arthos, Claudia Cicala, Anthony S. Fauci

Nat Immunol. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Nat Immunol. 2013 Dec; 14(12): 1256–1265. Published online 2013 Oct 27. doi: 10.1038/ni.2746

PMCID:: PMC3870659

Abstract Article PDF–1.4M

Select item 689109719.

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

Divya Achuthankutty, Roshan Singh Thakur, Peter Haahr, Saskia Hoffmann, Alexandros P. Drainas, Anna H. Bizard, Joachim Weischenfeldt, Ian D. Hickson, Niels Mailand

J Cell Biol. 2019 Dec 2; 218(12): 3943–3953. Published online 2019 Oct 15. doi: 10.1083/jcb.201905064

PMCID:: PMC6891097

Abstract Article PDF–2.7M

Select item 730831320.

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2

Chunqing Wang, Yongmei Li, Shuai Yan, Hao Wang, Xianfeng Shao, Mingming Xiao, Baicai Yang, Guoxuan Qin, Ruirui Kong, Ruibing Chen, Ning Zhang

Nat Commun. 2020; 11: 3162. Published online 2020 Jun 22. doi: 10.1038/s41467-020-16966-3

PMCID:: PMC7308313

Abstract Article PDF–2.9M

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