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Select item 111754431.

Extracellular ATP/P2X7 receptor, a regulatory axis of migration in ovarian carcinoma-derived cells

José David Nuñez-Ríos, Mauricio Reyna-Jeldes, Esperanza Mata-Martínez, Anaí del Rocío Campos-Contreras, Iván Lazcano-Sánchez, Adriana González-Gallardo, Mauricio Díaz-Muñoz, Claudio Coddou, Francisco G. Vázquez-Cuevas

PLoS One. 2024; 19(6): e0304062. Published online 2024 Jun 13. doi: 10.1371/journal.pone.0304062

PMCID:: PMC11175443

Abstract Article PDF–3.5M

Select item 109317472.

P2X7 Receptor in Dendritic Cells and Macrophages: Implications in Antigen Presentation and T Lymphocyte Activation

Claudio Acuña-Castillo, Alejandro Escobar, Moira García-Gómez, Vivienne C. Bachelet, Juan Pablo Huidobro-Toro, Daniela Sauma, Carlos Barrera-Avalos

Int J Mol Sci. 2024 Mar; 25(5): 2495. Published online 2024 Feb 21. doi: 10.3390/ijms25052495

PMCID:: PMC10931747

Abstract Article PDF–3.5M

Select item 108281513.

The P2X7 receptor in mucosal adaptive immunity

Fabio Grassi, Rebecca Marino

Purinergic Signal. 2024 Feb; 20(1): 9–19. Published online 2023 Apr 17. doi: 10.1007/s11302-023-09939-w

PMCID:: PMC10828151

Abstract Article PDF–2.0M

Select item 108158544.

Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk

Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Beata Sperlagh, Ian M. Anderson, Bill Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda

Int J Mol Sci. 2024 Jan; 25(2): 865. Published online 2024 Jan 10. doi: 10.3390/ijms25020865

PMCID:: PMC10815854

Abstract Article PDF–2.3M

Select item 107548005.

P2X7 receptor promotes migration and invasion of non-small cell lung cancer A549 cells through the PI3K/Akt pathways

Xue Bai, Qianqian Li, Xiaoxiang Peng, Xinyu Li, Cuicui Qiao, Yiqing Tang, Ronglan Zhao

Purinergic Signal. 2023 Dec; 19(4): 685–697. Published online 2023 Mar 1. doi: 10.1007/s11302-023-09928-z

PMCID:: PMC10754800

Abstract Article PDF–5.1M

Select item 107164206.

Purinergic P2X7 receptor expression increases in leukocytes from intra-abdominal septic patients

Helios Martínez-Banaclocha, Carlos García-Palenciano, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A. Ercole, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Julio Padilla-Rodríguez, Alberto Baroja-Mazo, Pablo Pelegrín, Juan José Martínez-García

Front Immunol. 2023; 14: 1297249. Published online 2023 Nov 29. doi: 10.3389/fimmu.2023.1297249

PMCID:: PMC10716420

Abstract Article PDF–3.6M

Select item 103802787.

The P2X7 Receptor, a Multifaceted Receptor in Alzheimer’s Disease

Kaitryn E. Ronning, Paul-Alexandre Déchelle-Marquet, Yueshen Che, Xavier Guillonneau, Florian Sennlaub, Cécile Delarasse

Int J Mol Sci. 2023 Jul; 24(14): 11747. Published online 2023 Jul 21. doi: 10.3390/ijms241411747

PMCID:: PMC10380278

Abstract Article PDF–748K

Select item 102476428.

Emerging roles of the P2X7 receptor in cancer pain

Ping Wu, Yin Wang, Yansong Liu, Yan Liu, Guohua Zhou, Xiaoqi Wu, Qingping Wen

Purinergic Signal. 2023 Jun; 19(2): 441–450. Published online 2022 Nov 19. doi: 10.1007/s11302-022-09902-1

PMCID:: PMC10247642

Abstract Article PDF–1.3M

Select item 101820879.

Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation

Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Berta Erdelyi-Hamza, Peter Petschner, Beata Sperlagh, Ian M. Anderson, John Francis William Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda

Sci Rep. 2023; 13: 7757. Published online 2023 May 12. doi: 10.1038/s41598-023-34781-w

PMCID:: PMC10182087

Abstract Article PDF–2.1M

Select item 1007651810.

The functional change of the P2X7R containing the Ala³⁴⁸ to Thr polymorphism is associated with the pathogenesis of gout

Man-Yun Li, Xuan Fang, Yan Ma, Xian-Yang Pan, Xiao-Juan Dai, Xiao-Mei Li, Xiao-Ling Li, Yi-Ping Wang, Jin-Hui Tao, Xiang-Pei Li

Sci Rep. 2023; 13: 5603. Published online 2023 Apr 5. doi: 10.1038/s41598-023-32365-2

PMCID:: PMC10076518

Abstract Article PDF–1.3M

Select item 994038711.

P2RX7 promotes osteosarcoma progression and glucose metabolism by enhancing c-Myc stabilization

Gaohong Sheng, Yuan Gao, Qing Ding, Ruizhuo Zhang, Tianqi Wang, Shaoze Jing, Hongqi Zhao, Tian Ma, Hua Wu, Yong Yang

J Transl Med. 2023; 21: 132. Published online 2023 Feb 20. doi: 10.1186/s12967-023-03985-z

PMCID:: PMC9940387

Abstract Article PDF–9.6M

Select item 982813512.

Continued P2X7 activation leads to mitochondrial fission and compromising microglial phagocytosis after subarachnoid haemorrhage

Tao Tao, Xiangxin Chen, Yan Zhou, Qiang Zheng, Sen Gao, Jinwei Wang, Pengfei Ding, Xiaojian Li, Zheng Peng, Yue Lu, Yongyue Gao, Zong Zhuang, Chun‐hua Hang, Wei Li

J Neurochem. 2022 Dec; 163(5): 419–437. Published online 2022 Nov 2. doi: 10.1111/jnc.15712

PMCID:: PMC9828135

Abstract Article PDF–8.3M

Select item 973655513.

Two Single Nucleotide Polymorphisms in the Purinergic Receptor P2X7 Gene Are Associated with Disease Severity in Multiple Sclerosis

Franca Rosa Guerini, Cristina Agliardi, Elisabetta Bolognesi, Milena Zanzottera, Domenico Caputo, Maria Barbara Pasanisi, Marco Rovaris, Mario Clerici

Int J Mol Sci. 2022 Dec; 23(23): 15381. Published online 2022 Dec 6. doi: 10.3390/ijms232315381

PMCID:: PMC9736555

Abstract Article PDF–594K

Select item 932248814.

Identification of Leukocyte Surface P2X7 as a Biomarker Associated with Alzheimer’s Disease

Yihan Li, Xin Huang, Christopher Fowler, Yen Y. Lim, Simon M. Laws, Noel Faux, James D. Doecke, Brett Trounson, Kelly Pertile, Rebecca Rumble, Vincent Doré, Victor L. Villemagne, Christopher C. Rowe, James S. Wiley, Paul Maruff, Colin L. Masters, Ben J. Gu

Int J Mol Sci. 2022 Jul; 23(14): 7867. Published online 2022 Jul 17. doi: 10.3390/ijms23147867

PMCID:: PMC9322488

Abstract Article PDF–4.5M

Select item 929801115.

The P2X7 purinergic receptor in intervertebral disc degeneration

Letizia Penolazzi, Leticia S. Bergamin, Elisabetta Lambertini, Valentina V. Poma, Alba C. Sarti, Pasquale De Bonis, Francesco Di Virgilio, Roberta Piva

J Cell Physiol. 2022 Feb; 237(2): 1418–1428. Published online 2021 Oct 19. doi: 10.1002/jcp.30611

PMCID:: PMC9298011

Abstract Article PDF–1.3M

Select item 916370116.

The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors

Xue-Fei Ma, Ting-Ting Wang, Wen-Hui Wang, Li Guan, Chang-Run Guo, Xing-Hua Li, Yun-Tao Lei, Ying-Zhe Fan, Xiao-Na Yang, Motoyuki Hattori, Osamu Nureki, Michael X. Zhu, Ye Yu, Yun Tian, Jin Wang

J Biol Chem. 2022 Jun; 298(6): 102002. Published online 2022 Apr 30. doi: 10.1016/j.jbc.2022.102002

PMCID:: PMC9163701

Abstract Article PDF–3.8M

Select item 916171017.

Soluble P2X7 Receptor Is Elevated in the Plasma of COVID-19 Patients and Correlates With Disease Severity

Julio García-Villalba, Laura Hurtado-Navarro, Alejandro Peñín-Franch, Cristina Molina-López, Laura Martínez-Alarcón, Diego Angosto-Bazarra, Alberto Baroja-Mazo, Pablo Pelegrin

Front Immunol. 2022; 13: 894470. Published online 2022 May 18. doi: 10.3389/fimmu.2022.894470

PMCID:: PMC9161710

Abstract Article PDF–3.9M

Select item 874524118.

Inherent P2X7 Receptors Regulate Macrophage Functions during Inflammatory Diseases

Wenjing Ren, Patrizia Rubini, Yong Tang, Tobias Engel, Peter Illes

Int J Mol Sci. 2022 Jan; 23(1): 232. Published online 2021 Dec 26. doi: 10.3390/ijms23010232

PMCID:: PMC8745241

Abstract Article PDF–1.4M

Select item 859961619.

P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells

Anna Pegoraro, Elena De Marchi, Manuela Ferracin, Elisa Orioli, Michele Zanoni, Cristian Bassi, Anna Tesei, Marina Capece, Emi Dika, Massimo Negrini, Francesco Di Virgilio, Elena Adinolfi

Cell Death Dis. 2021 Dec; 12(12): 1088. Published online 2021 Nov 16. doi: 10.1038/s41419-021-04378-0

PMCID:: PMC8599616

Abstract Article PDF–5.8M

Select item 835298620.

Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [¹⁸F]JNJ-64413739 PET and MRA-driven image derived input function

Nathalie Mertens, Mark E. Schmidt, Anja Hijzen, Donatienne Van Weehaeghe, Paulien Ravenstijn, Marleen Depre, Jan de Hoon, Koen Van Laere, Michel Koole

Sci Rep. 2021; 11: 16172. Published online 2021 Aug 9. doi: 10.1038/s41598-021-95715-y