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Select item 105119201.

Another Breach in the Wall: Impaired Epithelial DUOX2 Activity Fuels Metabolic Syndrome

Marianna Parlato, Nadine Cerf-Bensussan

Cell Mol Gastroenterol Hepatol. 2023; 16(4): 648–649. Published online 2023 Jul 28. doi: 10.1016/j.jcmgh.2023.07.005

PMCID:: PMC10511920

Article PDF–215K

Select item 101076412.

DUOX2 regulates secreted factors in virus‐infected respiratory epithelial cells that contribute to neutrophil attraction and activation

Dacquin M. Kasumba, Sandrine Huot, Elise Caron, Audray Fortin, Cynthia Laflamme, Natalia Zamorano Cuervo, Felix Lamontagne, Marc Pouliot, Nathalie Grandvaux

FASEB J. 2023 Feb; 37(2): e22765. Published online 2023 Jan 6. doi: 10.1096/fj.202201205R

PMCID:: PMC10107641

Abstract Article PDF–5.0M

Select item 79432733.

DUOX2 As a Potential Prognostic Marker which Promotes Cell Motility and Proliferation in Pancreatic Cancer

Meng Cao, Peng-Bo Zhang, Peng-Fei Wu, Qun Chen, Wan-Li Ge, Guo-Dong Shi, Jie Yin, Bao-Bao Cai, Shou-Ji Cao, Yi Miao, Kui-Rong Jiang

Biomed Res Int. 2021; 2021: 6530298. Published online 2021 Mar 2. doi: 10.1155/2021/6530298

PMCID:: PMC7943273

Abstract Article PDF–2.9M

Select item 78771864.

A truncated protein product of the germline variant of the DUOX2 gene leads to adenomatous polyposis

Mengyuan Yang, Yingxin Zhao, Yuwei Ding, Juan Wang, Yinuo Tan, Dong Xu, Ying Yuan

Cancer Biol Med. 2021 Feb 15; 18(1): 215–226. Published online 2021 Feb 15. doi: 10.20892/j.issn.2095-3941.2020.0305

Correction in:: Cancer Biol Med. 2022 Feb 15; 19(2): 263.

PMCID:: PMC7877186

Abstract Article PDF–1.2M

Select item 78178085.

Clinical and Genetic Features of a Large Monocentric Series of Familial Non-Medullary Thyroid Cancers

Valentina Cirello, Carla Colombo, Olga Karapanou, Gabriele Pogliaghi, Luca Persani, Laura Fugazzola

Front Endocrinol (Lausanne) 2020; 11: 589340. Published online 2021 Jan 7. doi: 10.3389/fendo.2020.589340

PMCID:: PMC7817808

Abstract Article PDF–386K

Select item 47138486.

DUOX2 Mutations Are Frequently Associated With Congenital Hypothyroidism in the Korean Population

Kyoung-Jin Park, Hyun-Kyung Park, Young-Jin Kim, Kyoung-Ryul Lee, Jong-Ho Park, June-Hee Park, Hyung-Doo Park, Soo-Youn Lee, Jong-Won Kim

Ann Lab Med. 2016 Mar; 36(2): 145–153. Published online 2015 Dec 18. doi: 10.3343/alm.2016.36.2.145

PMCID:: PMC4713848

Abstract Article PDF–291K

Select item 45497997.

Contribution of Dual Oxidase 2 (DUOX2) to Hyper-Radiosensitivity in Human Gastric Cancer Cells

Duc M. Nguyen, Palak R. Parekh, Elizabeth T. Chang, Navesh K. Sharma, France Carrier

Radiat Res. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: Radiat Res. 2015 Aug; 184(2): 151–160. Published online 2015 Jul 24. doi: 10.1667/rr13661.1

PMCID:: PMC4549799

Abstract Article PDF–935K

Select item 36416048.

IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response

Karin Fink, Lydie Martin, Esperance Mukawera, Stéfany Chartier, Xavier De Deken, Emmanuelle Brochiero, Françoise Miot, Nathalie Grandvaux

Cell Res. 2013 May; 23(5): 673–690. Published online 2013 Apr 2. doi: 10.1038/cr.2013.47

Correction in:: Cell Res. 2014 Apr; 24(4): 509.

PMCID:: PMC3641604

Abstract Article PDF–1.2M

Select item 36226759.

Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

YONGHZONG WU, SMITHA ANTONY, STEPHEN M. HEWITT, GUOJIAN JIANG, SHERRY X. YANG, JENNIFER L. MEITZLER, AGNES JUHASZ, JIAMO LU, HAN LIU, JAMES H. DOROSHOW, KRISHNENDU ROY

Int J Oncol. 2013 Apr; 42(4): 1229–1238. Published online 2013 Feb 11. doi: 10.3892/ijo.2013.1821

PMCID:: PMC3622675

Abstract Article PDF–1.3M

Select item 356393910.

Activation of Toll-Like Receptor 4 Is Required for the Synergistic Induction of Dual Oxidase 2 and Dual Oxidase A2 by Interferon-γ and Lipopolysaccharide in Human Pancreatic Cancer Cell Lines^§

Yongzhong Wu, Jiamo Lu, Smitha Antony, Agnes Juhasz, Han Liu, Guojian Jiang, Jennifer L. Meitzler, Melinda Hollingshead, Diana C. Haines, Donna Butcher, Krishnendu Roy, James H. Doroshow

J Immunol. Author manuscript; available in PMC 2014 Feb 15.

Published in final edited form as: J Immunol. 2013 Feb 15; 190(4): 1859–1872. Published online 2013 Jan 7. doi: 10.4049/jimmunol.1201725

PMCID:: PMC3563939

Abstract Article PDF–3.2M

Select item 313901111.

Structural Stability and Heme Binding Potential of the Truncated Human Dual Oxidase 2 (DUOX2) Peroxidase Domain

Jennifer L. Meitzler, Paul R. Ortiz de Montellano

Arch Biochem Biophys. Author manuscript; available in PMC 2012 Aug 15.

Published in final edited form as: Arch Biochem Biophys. 2011 Aug 15; 512(2): 197–203. Published online 2011 Jun 17. doi: 10.1016/j.abb.2011.05.021

PMCID:: PMC3139011

Abstract Article PDF–1.4M

Select item 292860712.

All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium

Angela Lee Linderholm, June Onitsuka, Changhong Xu, Maggie Chiu, Wai-Ming Lee, Richart W. Harper

Am J Physiol Lung Cell Mol Physiol. 2010 Aug; 299(2): L215–L221. Published online 2010 May 28. doi: 10.1152/ajplung.00015.2010

PMCID:: PMC2928607

Abstract Article

Select item 937151113.

Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation

Xiuqin Wei, Mei Xue, Chunbo Kang, Lei Gao, Mengqiao Zhang, Chao Ma, Wei Jia, Yufeng Zheng, Lei Cao, Pan Chen, Shujing Jiang, Fong-Fong Chu, Qiang Gao

Medicine (Baltimore) 2022 Aug 12; 101(32): e30028. Published online 2022 Aug 12. doi: 10.1097/MD.0000000000030028

PMCID:: PMC9371511

Abstract Article PDF–1.2M

Select item 808720314.

DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk

Helmut Grasberger, Andrew T. Magis, Elisa Sheng, Matthew P. Conomos, Min Zhang, Lea S. Garzotto, Guoqing Hou, Shrinivas Bishu, Hiroko Nagao-Kitamoto, Mohamad El-Zaatari, Sho Kitamoto, Nobuhiko Kamada, Ryan W. Stidham, Yasutada Akiba, Jonathan Kaunitz, Yael Haberman, Subra Kugathasan, Lee A. Denson, Gilbert S. Omenn, John Y. Kao

J Clin Invest. 2021 May 3; 131(9): e141676. Published online 2021 May 3. doi: 10.1172/JCI141676

PMCID:: PMC8087203

Abstract Article PDF–4.6M

Select item 787756115.

DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3

Xue Zhang, Jing Han, Li Feng, Lianghui Zhi, Da Jiang, Bin Yu, Zhenya Zhang, Bo Gao, Cong Zhang, Meng Li, Lianmei Zhao, Guiying Wang

Carcinogenesis. 2021 Jan; 42(1): 105–117. Published online 2020 Jun 12. doi: 10.1093/carcin/bgaa056

PMCID:: PMC7877561

Abstract Article PDF–1.4M

Select item 721242916.

DUOX2 and DUOXA2 Variants Confer Susceptibility to Thyroid Dysgenesis and Gland-in-situ With Congenital Hypothyroidism

Fengqi Wang, Yucui Zang, Miaomiao Li, Wenmiao Liu, Yangang Wang, Xiaolong Yu, Hua Li, Fang Wang, Shiguo Liu

Front Endocrinol (Lausanne) 2020; 11: 237. Published online 2020 Apr 21. doi: 10.3389/fendo.2020.00237

PMCID:: PMC7212429

Abstract Article PDF–440K

Select item 684248517.

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response

Sang Yeon Cho, Sungha Kim, Mi-Ju Son, Gwanghun Kim, Parul Singh, Ha Neul Kim, Hei-Gwon Choi, Heon Jong Yoo, Young Bok Ko, Byung Seok Lee, Hyuk Soo Eun

BMC Cancer. 2019; 19: 1078. Published online 2019 Nov 9. doi: 10.1186/s12885-019-6202-3

PMCID:: PMC6842485

Abstract Article PDF–4.1M

Select item 658811218.

DUOX2/DUOXA2 Mutations Frequently Cause Congenital Hypothyroidism that Evades Detection on Newborn Screening in the United Kingdom

Catherine Peters, Adeline K. Nicholas, Erik Schoenmakers, Greta Lyons, Shirley Langham, Eva G. Serra, Neil J. Sebire, Marina Muzza, Laura Fugazzola, Nadia Schoenmakers

Thyroid. 2019 Jun 1; 29(6): 790–801. Published online 2019 Jun 3. doi: 10.1089/thy.2018.0587

PMCID:: PMC6588112

Abstract Article PDF–6.0M

Select item 638976519.

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families

Yui Watanabe, Ryan J. Bruellman, Reham S. Ebrhim, Mohamed A. Abdullah, Alexandra M. Dumitrescu, Samuel Refetoff, Roy E. Weiss

Thyroid. 2019 Feb 1; 29(2): 302–304. Published online 2019 Feb 11. doi: 10.1089/thy.2018.0295

PMCID:: PMC6389765

Abstract Article PDF–176K

Select item 600690620.

DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells

Kyoung Ah Kang, Yea Seong Ryu, Mei Jing Piao, Kristina Shilnikova, Hee Kyoung Kang, Joo Mi Yi, Mathias Boulanger, Rosa Paolillo, Guillaume Bossis, Sung Young Yoon, Seong Bong Kim, Jin Won Hyun

Redox Biol. 2018 Jul; 17: 224–235. Published online 2018 Apr 23. doi: 10.1016/j.redox.2018.04.020

PMCID:: PMC6006906

Abstract Article PDF–1.7M

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