PMC Links for Gene (Select 5058) - PMC

Susanne Horn, Margaret Au, Lina Basel-Salmon, Pinar Bayrak-Toydemir, Alexander Chapin, Lior Cohen, Mariet W Elting, John M Graham, Jr, Claudia Gonzaga-Jauregui, Osnat Konen, Max Holzer, Johannes Lemke, Christine E Miller, Linda K Rey, Nicole I Wolf, Marjan M Weiss, Quinten Waisfisz, Ghayda M Mirzaa, Dagmar Wieczorek, Heinrich Sticht, Rami Abou Jamra

Brain. 2019 Nov; 142(11): 3351–3359. Published online 2019 Aug 29. doi: 10.1093/brain/awz264

PMCID:: PMC6821231

Abstract Article PDF–1.0M

Select item 67562375.

Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis

Karla C. Williams, Mario A. Cepeda, Sumreen Javed, Karlee Searle, Katie M. Parkins, Ashley V. Makela, Amanda M. Hamilton, Sepideh Soukhtehzari, Yohan Kim, Alan B. Tuck, John A. Ronald, Paula J. Foster, Ann F. Chambers, Hon S. Leong

Oncogene. 2019; 38(19): 3598–3615. Published online 2019 Jan 16. doi: 10.1038/s41388-018-0667-4

PMCID:: PMC6756237

Abstract Article PDF–5.2M

Select item 64645756.

The role of PAK1 in the sensitivity of kidney epithelial cells to ischemia-like conditions

Evan R. Zynda, Mitchell H. Maloy, Eugene S. Kandel

Cell Cycle. 2019; 18(5): 596–604. Published online 2019 Feb 11. doi: 10.1080/15384101.2019.1578149

PMCID:: PMC6464575

Abstract Article PDF–1010K

Select item 61743227.

Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder

Frederike L. Harms, Katja Kloth, Annette Bley, Jonas Denecke, René Santer, Davor Lessel, Maja Hempel, Kerstin Kutsche

Am J Hum Genet. 2018 Oct 4; 103(4): 579–591. Published online 2018 Oct 4. doi: 10.1016/j.ajhg.2018.09.005

PMCID:: PMC6174322

Abstract Article PDF–2.1M

Select item 59738178.

Targeting PAK1

Galina Semenova, Jonathan Chernoff

Biochem Soc Trans. Author manuscript; available in PMC 2018 May 29.

Published in final edited form as: Biochem Soc Trans. 2017 Feb 8; 45(1): 79–88. doi: 10.1042/BST20160134

PMCID:: PMC5973817

Abstract Article PDF–624K

Select item 59606439.

Modulation of store-operated calcium entry and nascent adhesion by p21-activated kinase 1

In-Sook Jeon, Hye-Ryun Kim, Eun-Young Shin, Eung-Gook Kim, Heon-Seok Han, Jin-Tae Hong, Hak-Kyo Lee, Ki-Duk Song, Joong-Kook Choi

Exp Mol Med. 2018 May; 50(5): 65. Published online 2018 May 21. doi: 10.1038/s12276-018-0093-2

PMCID:: PMC5960643

Abstract Article PDF–1.7M

Select item 541024510.

Clinicopathological signature of p21-activated kinase 1 in prostate cancer and its regulation of proliferation and autophagy via the mTOR signaling pathway

Zhanyu Wang, Guojin Jia, Yan Li, Jikai Liu, Jinfang Luo, Jihong Zhang, Guoxiong Xu, Gang Chen

Oncotarget. 2017 Apr 4; 8(14): 22563–22580. Published online 2017 Feb 6. doi: 10.18632/oncotarget.15124

PMCID:: PMC5410245

Abstract Article PDF–15M

Select item 539214211.

P21-Activated Kinase 1 Regulates Resistance to BRAF Inhibition in Human Cancer Cells

Mahamat Babagana, Sydney Johnson, Hannah Slabodkin, Wiam Bshara, Carl Morrison, Eugene S. Kandel

Mol Carcinog. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Mol Carcinog. 2017 May; 56(5): 1515–1525. Published online 2017 Feb 23. doi: 10.1002/mc.22611

PMCID:: PMC5392142

Abstract Article PDF–1.1M

Select item 512507612.

Effects of p21-activated kinase 1 inhibition on 11q13 amplified ovarian cancer cells

Tatiana Y. Prudnikova, Olga Villamar-Cruz, Sonali J. Rawat, Kathy Q. Cai, Jonathan Chernoff

Oncogene. Author manuscript; available in PMC 2016 Nov 28.

Published in final edited form as: Oncogene. 2016 Apr 28; 35(17): 2178–2185. Published online 2015 Aug 10. doi: 10.1038/onc.2015.278

PMCID:: PMC5125076

Abstract Article PDF–835K

Select item 505366013.

p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysis

Fang Fang, Jian Pan, Yi-Ping Li, Gang Li, Li-Xiao Xu, Guang-Hao Su, Zhi-Heng Li, Xing Feng, Jian Wang

Oncotarget. 2016 May 10; 7(19): 27422–27429. Published online 2016 Mar 24. doi: 10.18632/oncotarget.8320

PMCID:: PMC5053660

Abstract Article PDF–3.2M

Select item 500468714.

Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer

Nhi Huynh, Arthur Shulkes, Graham Baldwin, Hong He

Cancer Biol Ther. 2016 Aug; 17(8): 813–823. Published online 2016 Jun 3. doi: 10.1080/15384047.2016.1195045

PMCID:: PMC5004687

Abstract Article PDF–1.1M

Select item 494357515.

Pak1, adjuvant tamoxifen therapy, and breast cancer recurrence risk in a Danish population-based study

Thomas P. Ahern, Deirdre P. Cronin-Fenton, Timothy L. Lash, Henrik Toft Sørensen, Anne Gulbech Ording, Stephen J. Hamilton-Dutoit, Ylva Hellberg

Acta Oncol. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Acta Oncol. 2016 Jun; 55(6): 734–741. Published online 2016 Apr 8. doi: 10.3109/0284186X.2016.1150606

PMCID:: PMC4943575

Abstract Article PDF–1.4M

Select item 489624116.

Potential role of p21 Activated Kinase 1 (PAK1) in the invasion and motility of oral cancer cells

Muraleedharan Parvathy, Sreeharshan Sreeja, Rakesh Kumar, Madhavan Radhakrishna Pillai

BMC Cancer. 2016; 16(Suppl 1): 293. Published online 2016 May 16. doi: 10.1186/s12885-016-2263-8

PMCID:: PMC4896241

Abstract Article PDF–1.7M

Select item 473007417.

Overexpression of PAK-1 is an independent predictor of disease recurrence in colorectal carcinoma

Jaudah Al-Maghrabi, Eman Emam, Wafaey Gomaa, Doaa Al-Qaydy, Basim Al-Maghrabi, Abdelbaset Buhmeida, Adel Abuzenadah, Mohammed Al-Qahtani, Mahmoud Al-Ahwal

Int J Clin Exp Pathol. 2015; 8(12): 15895–15902. Published online 2015 Dec 1.

PMCID:: PMC4730074

Abstract Article PDF–926K

Select item 471534718.

FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine

Dannel Yeo, Hong He, Oneel Patel, Andrew M. Lowy, Graham S. Baldwin, Mehrdad Nikfarjam

BMC Cancer. 2016; 16: 24. Published online 2016 Jan 16. doi: 10.1186/s12885-016-2057-z

PMCID:: PMC4715347

Abstract Article PDF–2.6M

Select item 467400419.

Potentially functional polymorphisms in PAK1 are associated with risk of lung cancer in a Chinese population

Mingfeng Zheng, Jia Liu, Meng Zhu, Rong Yin, Juncheng Dai, Jie Sun, Wei Shen, Yong Ji, Guangfu Jin, Hongxia Ma, Jing Dong, Lin Xu, Zhibin Hu, Hongbing Shen

Cancer Med. 2015 Nov; 4(11): 1781–1787. Published online 2015 Sep 17. doi: 10.1002/cam4.524