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Select item 56469561.

Co-expression of Axin and APC gene fragments inhibits colorectal cancer cell growth via regulation of the Wnt signaling pathway

Meili Xu, Xianling Liu, Yan Xu, Shicong Zhu, Yawen Gao

Mol Med Rep. 2017 Oct; 16(4): 3783–3790. Published online 2017 Jul 21. doi: 10.3892/mmr.2017.7049

PMCID:: PMC5646956

Abstract Article PDF–1.6M

Select item 33591262.

Regulation of E2F1 by APC/C^Cdh1 via K11 linkage-specific ubiquitin chain formation

Varija N. Budhavarapu, Erin D. White, Christina S. Mahanic, Ligong Chen, Fang-Tsyr Lin, Weei-Chin Lin

Cell Cycle. 2012 May 15; 11(10): 2030–2038. doi: 10.4161/cc.20643

PMCID:: PMC3359126

Abstract Article PDF–1.2M

Select item 3877533.

The Apc5 Subunit of the Anaphase-Promoting Complex/Cyclosome Interacts with Poly(A) Binding Protein and Represses Internal Ribosome Entry Site-Mediated Translation

Nadejda Koloteva-Levine, Dalia Pinchasi, Idan Pereman, Amit Zur, Michael Brandeis, Orna Elroy-Stein

Mol Cell Biol. 2004 May; 24(9): 3577–3587. doi: 10.1128/MCB.24.9.3577-3587.2004

PMCID:: PMC387753

Abstract Article PDF–462K

Select item 31026004.

The emerging role of APC/C^Cdh1 in controlling differentiation, genomic stability and tumor suppression

Ralph Wäsch, Jonathan A. Robbins, Frederick R. Cross

Oncogene. Author manuscript; available in PMC 2011 May 26.

Published in final edited form as: Oncogene. 2010 Jan 7; 29(1): 1–10. Published online 2009 Oct 12. doi: 10.1038/onc.2009.325

PMCID:: PMC3102600

Abstract Article PDF–1.1M

Select item 33904095.

Proteasome-Dependent Disruption of the E3 Ubiquitin Ligase Anaphase-Promoting Complex by HCMV Protein pUL21a

Anthony R. Fehr, Nathaniel C. Gualberto, John Paul Savaryn, Scott S. Terhune, Dong Yu

PLoS Pathog. 2012 Jul; 8(7): e1002789. Published online 2012 Jul 5. doi: 10.1371/journal.ppat.1002789

PMCID:: PMC3390409

Abstract Article PDF–3.2M

Select item 29505776.

Inactivation and Disassembly of the Anaphase-Promoting Complex during Human Cytomegalovirus Infection Is Associated with Degradation of the APC5 and APC4 Subunits and Does Not Require UL97-Mediated Phosphorylation of Cdh1

Karen Tran, Jeremy P. Kamil, Donald M. Coen, Deborah H. Spector

J Virol. 2010 Oct; 84(20): 10832–10843. Published online 2010 Aug 4. doi: 10.1128/JVI.01260-10

PMCID:: PMC2950577

Abstract Article PDF–2.0M

Select item 42724267.

Deregulation of Rb-E2F1 Axis Causes Chromosomal Instability by Engaging the Transactivation Function of Cdc20–Anaphase-Promoting Complex/Cyclosome

Somsubhra Nath, Abhishek Chowdhury, Sanjib Dey, Anirban Roychoudhury, Abira Ganguly, Dibyendu Bhattacharyya, Susanta Roychoudhury

Mol Cell Biol. 2015 Jan; 35(2): 356–369. Prepublished online 2014 Nov 3. Published online 2014 Dec 22. doi: 10.1128/MCB.00868-14

PMCID:: PMC4272426

Abstract Article PDF–2.6M

Select item 180318.

Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons

Christian Gieffers, Beate H. Peters, Edgar R. Kramer, Carlos G. Dotti, Jan-Michael Peters

Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20): 11317–11322. doi: 10.1073/pnas.96.20.11317

PMCID:: PMC18031

Abstract Article PDF–383K

Select item 38118969.

The G₂/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20

Hui-Jun Lim, Nevena V. Dimova, Meng-Kwang Marcus Tan, Frederic D. Sigoillot, Randall W. King, Yang Shi

Mol Cell Biol. 2013 Nov; 33(21): 4166–4180. doi: 10.1128/MCB.00689-13

PMCID:: PMC3811896

Abstract Article PDF–1.3M

Select item 29182210.

Mitotic regulation of the human anaphase-promoting complex by phosphorylation

Claudine Kraft, Franz Herzog, Christian Gieffers, Karl Mechtler, Anja Hagting, Jonathon Pines, Jan-Michael Peters

EMBO J. 2003 Dec 15; 22(24): 6598–6609. doi: 10.1093/emboj/cdg627

PMCID:: PMC291822

Abstract Article PDF–500K

Select item 578779711.

Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway

Chu Zhu, Xinyan Ji, Haitao Zhang, Qi Zhou, Xiaolei Cao, Mei Tang, Yuan Si, Huan Yan, Li Li, Tingbo Liang, Xin-Hua Feng, Bin Zhao

J Biol Chem. 2018 Jan 26; 293(4): 1178–1191. Published online 2017 Nov 28. doi: 10.1074/jbc.RA117.000392

PMCID:: PMC5787797

Abstract Article PDF–3.8M

Select item 156041512.

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

Julie J. Miller, Matthew K. Summers, David V. Hansen, Maxence V. Nachury, Norman L. Lehman, Alex Loktev, Peter K. Jackson

Genes Dev. 2006 Sep 1; 20(17): 2410–2420. doi: 10.1101/gad.1454006

PMCID:: PMC1560415

Abstract Article PDF–526K

Select item 901883513.

Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription

Sang Bae Lee, Luciano Garofano, Aram Ko, Fulvio D’Angelo, Brulinda Frangaj, Danika Sommer, Qiwen Gan, KyeongJin Kim, Timothy Cardozo, Antonio Iavarone, Anna Lasorella

Nat Commun. 2022; 13: 2089. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29502-2

PMCID:: PMC9018835

Abstract Article PDF–2.1M

Select item 566981414.

Assembly and Function of Heterotypic Ubiquitin Chains in Cell Cycle and Protein Quality Control

Richard G. Yau, Kerstin Doerner, Erick R. Castellanos, Diane L. Haakonsen, Achim Werner, Nan Wang, X. William Yang, Nadia Martinez-Martin, Marissa L. Matsumoto, Vishva M. Dixit, Michael Rape

Cell. Author manuscript; available in PMC 2018 Nov 2.

Published in final edited form as: Cell. 2017 Nov 2; 171(4): 918–933.e20. Published online 2017 Oct 12. doi: 10.1016/j.cell.2017.09.040

PMCID:: PMC5669814

Abstract Article PDF–3.1M

Select item 427286515.

Mechanism of polyubiquitination by human Anaphase Promoting Complex: RING repurposing for ubiquitin chain assembly

Nicholas G. Brown, Edmond R. Watson, Florian Weissmann, Marc A. Jarvis, Ryan VanderLinden, Christy R. R. Grace, Jeremiah J. Frye, Renping Qiao, Prakash Dube, Georg Petzold, Shein Ei Cho, Omar Alsharif, Ju Bao, Iain F. Davidson, Jie Zheng, Amanda Nourse, Igor Kurinov, Jan-Michael Peters, Holger Stark, Brenda A. Schulman

Mol Cell. Author manuscript; available in PMC 2015 Oct 23.

Published in final edited form as: Mol Cell. 2014 Oct 23; 56(2): 246–260. Published online 2014 Oct 9. doi: 10.1016/j.molcel.2014.09.009

PMCID:: PMC4272865

Abstract Article PDF–3.2M

Select item 349806216.

APC15 mediates CDC20 auto-ubiquitylation by APC/C^MCC and MCC disassembly

Kristina Uzunova, Billy T. Dye, Hannelore Schutz, Rene Ladurner, Georg Petzold, Yusuke Toyoda, Marc A. Jarvis, Nicholas G. Brown, Ina Poser, Maria Novatchkova, Karl Mechtler, Anthony A. Hyman, Holger Stark, Brenda A. Schulman, Jan-Michael Peters

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nat Struct Mol Biol. 2012 Nov; 19(11): 1116–1123. Published online 2012 Sep 24. doi: 10.1038/nsmb.2412

PMCID:: PMC3498062

Abstract Article PDF–3.2M

Select item 216944317.

Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase

Izabela Sumara, Elisabeth Vorlaufer, Christian Gieffers, Beate H. Peters, Jan-Michael Peters

J Cell Biol. 2000 Nov 13; 151(4): 749–762. doi: 10.1083/jcb.151.4.749

PMCID:: PMC2169443

Abstract Article PDF–661K

Select item 486849118.

Mechanism of APC/C^CDC20 activation by mitotic phosphorylation

Renping Qiao, Florian Weissmann, Masaya Yamaguchi, Nicholas G. Brown, Ryan VanderLinden, Richard Imre, Marc A. Jarvis, Michael R. Brunner, Iain F. Davidson, Gabriele Litos, David Haselbach, Karl Mechtler, Holger Stark, Brenda A. Schulman, Jan-Michael Peters

Proc Natl Acad Sci U S A. 2016 May 10; 113(19): E2570–E2578. Published online 2016 Apr 25. doi: 10.1073/pnas.1604929113

PMCID:: PMC4868491

Abstract Article PDF–1.4M

Select item 388259119.

Transcriptional Intermediary Factor 1? binds to the Anaphase-Promoting Complex/Cyclosome and promotes mitosis

Garry G. Sedgwick, Kelly Townsend, Ashley Martin, Neil J. Shimwell, Roger J. A. Grand, Grant S. Stewart, Jakob Nilsson, Andrew S. Turnell

Oncogene. Author manuscript; available in PMC 2014 Mar 26.

Published in final edited form as: Oncogene. 2013 Sep 26; 32(39): 10.1038/onc.2012.501. Published online 2012 Nov 19. doi: 10.1038/onc.2012.501

PMCID:: PMC3882591

Abstract Article PDF–4.1M

Select item 303370420.

Lesson from the Stoichiometry Determination of the Cohesin Complex: A Short Protease Mediated Elution Increases the Recovery from Cross-Linked Antibody-Conjugated Beads

Johann Holzmann, Johannes Fuchs, Peter Pichler, Jan-Michael Peters, Karl Mechtler

J Proteome Res. 2011 Feb 4; 10(2): 780–789. Published online 2010 Nov 3. doi: 10.1021/pr100927x

PMCID:: PMC3033704

Abstract Article PDF–2.5M

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