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Select item 79334671.

Elafin as a Predictive Biomarker of Acute Skin Graft-Versus-Host Disease After Haploidentical Stem Cell Transplantation Using Post-Transplant High-Dose Cyclophosphamide

Laura Solán, Diego Carbonell, Paula Muñiz, Nieves Dorado, Elena Landete, María Chicano-Lavilla, Javier Anguita, Jorge Gayoso, Mi Kwon, José Luis Díez-Martín, Carolina Martínez-Laperche, Ismael Buño

Front Immunol. 2021; 12: 516078. Published online 2021 Feb 19. doi: 10.3389/fimmu.2021.516078

PMCID:: PMC7933467

Abstract Article PDF–748K

Select item 71560982.

High circulating elafin levels are associated with Crohn’s disease-associated intestinal strictures

Jiani Wang, Christina Ortiz, Lindsey Fontenot, Ying Xie, Wendy Ho, S. Anjani Mattai, David Q. Shih, Hon Wai Koon

PLoS One. 2020; 15(4): e0231796. Published online 2020 Apr 14. doi: 10.1371/journal.pone.0231796

PMCID:: PMC7156098

Abstract Article PDF–3.1M

Select item 43264853.

Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence

Joseph A Caruso, Cansu Karakas, Jing Zhang, Min Yi, Constance Albarracin, Aysegul Sahin, Melissa Bondy, Jinsong Liu, Kelly K Hunt, Khandan Keyomarsi

Breast Cancer Res. 2014; 16: 3417. Published online 2014 Dec 31. doi: 10.1186/s13058-014-0497-4

Correction in:: Breast Cancer Res. 2015; 17(1): 87.

PMCID:: PMC4326485

Abstract Article PDF–1.5M

Select item 42844034.

Urinary Elafin and Kidney Injury in Hematopoietic Cell Transplant Recipients

Sangeeta Hingorani, Laura S. Finn, Emily Pao, Rick Lawler, Gary Schoch, George B. McDonald, Behzad Najafian, Brenda Sandmaier, Ted Gooley

Clin J Am Soc Nephrol. 2015 Jan 7; 10(1): 12–20. Published online 2014 Nov 11. doi: 10.2215/CJN.01840214

PMCID:: PMC4284403

Abstract Article

Select item 42195325.

Novel role of the serine protease inhibitor elafin in gluten-related disorders

Heather J. Galipeau, Michelle Wiepjes, Jean-Paul Motta, Jessica D. Schulz, Jennifer Jury, Jane M. Natividad, Ines Pinto-Sanchez, Daniel Sinclair, Perrine Rousset, Rebeca Martin-Rosique, Luis Bermudez-Humaran, Jean Christophe Leroux, Joseph Murray, Edgardo Smecuol, Julio C. Bai, Nathalie Vergnolle, Philippe Langella, Elena F Verdu

Am J Gastroenterol. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Am J Gastroenterol. 2014 May; 109(5): 748–756. Published online 2014 Apr 8. doi: 10.1038/ajg.2014.48

PMCID:: PMC4219532

Abstract Article PDF–1.1M

Select item 41480376.

Functional Characterization of Polymorphisms in the Peptidase Inhibitor 3 (Elafin) Gene and Validation of Their Contribution to Risk of Acute Respiratory Distress Syndrome

Paula Tejera, D. Shane O’Mahony, Caroline A. Owen, Yongyue Wei, Zhaoxi Wang, Kushagra Gupta, Li Su, Jesus Villar, Mark Wurfel, David C. Christiani

Am J Respir Cell Mol Biol. 2014 Aug; 51(2): 262–272. doi: 10.1165/rcmb.2013-0238OC

PMCID:: PMC4148037

Abstract Article PDF–780K

Select item 41121767.

Elafin drives poor outcome in high grade serous ovarian cancers and basal-like breast tumors

S. Intidhar Labidi-Galy, Adam Clauss, Vivian Ng, Sekhar Duraisamy, Kevin M. Elias, Hui-Ying Piao, Erhan Bilal, Rachel A. Davidowitz, Yiling Lu, Gayane Badalian-Very, Balázs Györffy, Un-Beom Kang, Scott B. Ficarro, Shridar Ganesan, Gordon B. Mills, Jarrod A. Marto, Ronny Drapkin

Oncogene. Author manuscript; available in PMC 2015 Jul 15.

Published in final edited form as: Oncogene. 2015 Jan 15; 34(3): 373–383. Published online 2014 Jan 27. doi: 10.1038/onc.2013.562

PMCID:: PMC4112176

Abstract Article PDF–1.2M

Select item 37002828.

Antiviral Activity of Trappin-2 and Elafin In Vitro and In Vivo against Genital Herpes

Anna G. Drannik, Kakon Nag, Jean-Michel Sallenave, Kenneth L. Rosenthal

J Virol. 2013 Jul; 87(13): 7526–7538. doi: 10.1128/JVI.02243-12

PMCID:: PMC3700282

Abstract Article PDF–3.8M

Select item 36727709.

Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer

Kelly K Hunt, Hannah Wingate, Tomoya Yokota, Yanna Liu, Gordon B Mills, Fan Zhang, Bingliang Fang, Chun-Hui Su, Ming Zhang, Min Yi, Khandan Keyomarsi

Breast Cancer Res. 2013; 15(1): R3. Published online 2013 Jan 15. doi: 10.1186/bcr3374

PMCID:: PMC3672770

Abstract Article PDF–1.7M

Select item 295899910.

Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa

Audrey Bellemare, Nathalie Vernoux, Sébastien Morin, Stéphane M Gagné, Yves Bourbonnais

BMC Microbiol. 2010; 10: 253. Published online 2010 Oct 8. doi: 10.1186/1471-2180-10-253

PMCID:: PMC2958999

Abstract Article PDF–3.4M

Select item 289541011.

Elafin is a biomarker of graft versus host disease of the skin

Sophie Paczesny, Thomas M Braun, John E Levine, Jason Hogan, Jeffrey Crawford, Bryan Coffing, Stephen Olsen, Sung W Choi, Hong Wang, Vitor Faca, Sharon Pitteri, Qing Zhang, Alice Chin, Carrie Kitko, Shin Mineishi, Gregory Yanik, Edward Peres, David Hanauer, Ying Wang, Pavan Reddy, Samir Hanash, James LM Ferrara

Sci Transl Med. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Sci Transl Med. 2010 Jan 6; 2(13): 13ra2. doi: 10.1126/scitranslmed.3000406

PMCID:: PMC2895410

Abstract Article PDF–920K

Select item 281446312.

Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract

Mimi Ghosh, Zheng Shen, John V Fahey, Susan Cu-Uvin, Kenneth Mayer, Charles R Wira

Immunology. 2010 Feb; 129(2): 207–219. doi: 10.1111/j.1365-2567.2009.03165.x

PMCID:: PMC2814463

Abstract Article PDF–301K

Select item 281435413.

Overexpression of Elafin in Ovarian Carcinoma Is Driven by Genomic Gains and Activation of the Nuclear Factor κB Pathway and Is Associated with Poor Overall Survival

Adam Clauss, Vivian Ng, Joyce Liu, Huiying Piao, Moises Russo, Natalie Vena, Qing Sheng, Michelle S Hirsch, Tomas Bonome, Ursula Matulonis, Azra H Ligon, Michael J Birrer, Ronny Drapkin

Neoplasia. 2010 Feb; 12(2): 161–172. doi: 10.1593/neo.91542

PMCID:: PMC2814354

Abstract Article PDF–4.8M

Select item 278440714.

Genetic Polymorphisms of Peptidase Inhibitor 3 (Elafin) Are Associated with Acute Respiratory Distress Syndrome

Paula Tejera, Zhaoxi Wang, Rihong Zhai, Li Su, Chau-Chyun Sheu, Deanne M. Taylor, Feng Chen, Michelle N. Gong, B. Taylor Thompson, David C. Christiani

Am J Respir Cell Mol Biol. 2009 Dec; 41(6): 696–704. Published online 2009 Feb 27. doi: 10.1165/rcmb.2008-0410OC

PMCID:: PMC2784407

Abstract Article PDF–439K

Select item 239625015.

A Genome-Wide Expression Analysis in Blood Identifies Pre-Elafin as a Biomarker in ARDS

Zhaoxi Wang, Douglas Beach, Li Su, Rihong Zhai, David C. Christiani

Am J Respir Cell Mol Biol. 2008 Jun; 38(6): 724–732. Published online 2008 Jan 18. doi: 10.1165/rcmb.2007-0354OC

PMCID:: PMC2396250

Abstract Article PDF–323K

Select item 226730016.

Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema

Alain Doucet, Dominique Bouchard, Marie France Janelle, Audrey Bellemare, Stéphane Gagné, Guy M. Tremblay, Yves Bourbonnais

Biochem J. 2007 Aug 1; 405(Pt 3): 455–463. Prepublished online 2007 May 10. Published online 2007 Jul 13. doi: 10.1042/BJ20070020

PMCID:: PMC2267300

Abstract Article PDF–552K

Select item 222474217.

Human Pre-Elafin Inhibits a Pseudomonas aeruginosa-Secreted Peptidase and Prevents Its Proliferation in Complex Media

Audrey Bellemare, Nathalie Vernoux, Dany Morisset, Yves Bourbonnais

Antimicrob Agents Chemother. 2008 Feb; 52(2): 483–490. Published online 2007 Nov 19. doi: 10.1128/AAC.00585-07

PMCID:: PMC2224742

Abstract Article PDF–442K

Select item 150814018.

Identification of novel functional sequence variants in the gene for peptidase inhibitor 3

Mahboob A Chowdhury, Helena Kuivaniemi, Roberto Romero, Samuel Edwin, Tinnakorn Chaiworapongsa, Gerard Tromp

BMC Med Genet. 2006; 7: 49. Published online 2006 May 23. doi: 10.1186/1471-2350-7-49

PMCID:: PMC1508140

Abstract Article PDF–625K

Select item 50756519.

Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia.

R Pfundt, F van Ruissen, I M van Vlijmen-Willems, H A Alkemade, P L Zeeuwen, P H Jap, H Dijkman, J Fransen, H Croes, P E van Erp, J Schalkwijk

J Clin Invest. 1996 Sep 15; 98(6): 1389–1399. doi: 10.1172/JCI118926

PMCID:: PMC507565

Summary PDF–800K

Select item 854624320.

Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency

Andrew J. Sweatt, Kazuya Miyagawa, Christopher J. Rhodes, Shalina Taylor, Patricia A. Del Rosario, Andrew Hsi, Francois Haddad, Edda Spiekerkoetter, Michal Bental-Roof, Richard D. Bland, Emilia M. Swietlik, Stefan Gräf, Martin R. Wilkins, Nicholas W. Morrell, Mark R. Nicolls, Marlene Rabinovitch, Roham T. Zamanian

Chest. 2021 Oct; 160(4): 1442–1458. Published online 2021 Jun 26. doi: 10.1016/j.chest.2021.06.028

PMCID:: PMC8546243

Abstract Article PDF–1.8M

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