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Select item 98983401.

PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization

Ying Zhang, Yelong Chen, Chuangzhen Chen, Huancheng Guo, Chunbin Zhou, Hu Wang, Zhaoyong Liu

Clin Exp Metastasis. 2023; 40(1): 79–93. Published online 2022 Nov 5. doi: 10.1007/s10585-022-10192-5

Correction in:: Clin Exp Metastasis. 2024; 41(1): 79–80.

PMCID:: PMC9898340

Abstract Article PDF–14M

Select item 86338542.

Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification

Yinglang Zhang, Zhe Zhang, Wei Zhang, Hailong Hu, Guochang Bao

Dis Markers. 2021; 2021: 7694239. Published online 2021 Nov 23. doi: 10.1155/2021/7694239

PMCID:: PMC8633854

Abstract Article PDF–5.2M

Select item 84435763.

PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes

Takahito Ohira, Suguru Nakagawa, Jumpei Takeshita, Hiroyuki Aburatani, Hiroyuki Kugoh

Sci Rep. 2021; 11: 18405. Published online 2021 Sep 15. doi: 10.1038/s41598-021-97791-6

PMCID:: PMC8443576

Abstract Article PDF–1.5M

Select item 82542364.

Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer

Yichao Li, Sushil K. Jaiswal, Rupleen Kaur, Dana Alsaadi, Xiaoyu Liang, Frank Drews, Julie A. DeLoia, Thomas Krivak, Hanna M. Petrykowska, Valer Gotea, Lonnie Welch, Laura Elnitski

BMC Cancer. 2021; 21: 768. Published online 2021 Jul 3. doi: 10.1186/s12885-021-08276-8

PMCID:: PMC8254236

Abstract Article PDF–2.3M

Select item 74949905.

Bioinformatics analysis of prognostic value of PITX1 gene in breast cancer

Qiaoyun Wang, Shuai Zhao, Lei Gan, Zhixiang Zhuang

Biosci Rep. 2020 Sep 30; 40(9): BSR20202537. Published online 2020 Sep 10. doi: 10.1042/BSR20202537

PMCID:: PMC7494990

Abstract Article PDF–1.8M

Select item 64246126.

Hypersensitive interferon responses in lupus keratinocytes reveal key mechanistic determinants in cutaneous lupus

Lam C. Tsoi, Grace A. Hile, Celine C. Berthier, Mrinal K. Sarkar, Tamra J. Reed, Jianhua Liu, Ranjitha Uppala, Matthew Patrick, Kalpana Raja, Xianying Xing, Enze Xing, Kevin He, Johann E. Gudjonsson, J. Michelle Kahlenberg

J Immunol. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: J Immunol. 2019 Apr 1; 202(7): 2121–2130. Published online 2019 Feb 11. doi: 10.4049/jimmunol.1800650

PMCID:: PMC6424612

Abstract Article PDF–1.9M

Select item 59417927.

Abnormal PITX1 gene methylation in adolescent idiopathic scoliosis: a pilot study

Benlong Shi, Liang Xu, Saihu Mao, Leilei Xu, Zhen Liu, Xu Sun, Zezhang Zhu, Yong Qiu

BMC Musculoskelet Disord. 2018; 19: 138. Published online 2018 May 9. doi: 10.1186/s12891-018-2054-2

PMCID:: PMC5941792

Abstract Article PDF–944K

Select item 58068918.

Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas

Verena Sailer, Arthur Charpentier, Joern Dietrich, Timo J. Vogt, Alina Franzen, Friedrich Bootz, Dimo Dietrich, Andreas Schroeck

PLoS One. 2018; 13(2): e0192742. Published online 2018 Feb 9. doi: 10.1371/journal.pone.0192742

PMCID:: PMC5806891

Abstract Article PDF–2.5M

Select item 46148119.

PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

Sharon Mudie, Daniel Bandarra, Michael Batie, John Biddlestone, Sonia Moniz, Brian Ortmann, Alena Shmakova, Sonia Rocha

Cell Cycle. 2014 Dec 15; 13(24): 3878–3891. Published online 2015 Jan 3. doi: 10.4161/15384101.2014.972889

PMCID:: PMC4614811

Abstract Article PDF–956K

Select item 335526010.

Deletions in PITX1 cause a spectrum of lower-limb malformations including mirror-image polydactyly

Eva Klopocki, Christian Kähler, Nicola Foulds, Hitesh Shah, Benjamin Joseph, Hermann Vogel, Sabine Lüttgen, Rainer Bald, Regina Besoke, Karsten Held, Stefan Mundlos, Ingo Kurth

Eur J Hum Genet. 2012 Jun; 20(6): 705–708. Published online 2012 Jan 18. doi: 10.1038/ejhg.2011.264

PMCID:: PMC3355260

Abstract Article PDF–331K

Select item 267512911.

Expression of pituitary homeobox 1 gene in human gastric carcinogenesis and its clinicopathological significance

Ya-Nan Chen, Hong Chen, Yan Xu, Xue Zhang, Yang Luo

World J Gastroenterol. 2008 Jan 14; 14(2): 292–297. Published online 2008 Jan 14. doi: 10.3748/wjg.14.292

PMCID:: PMC2675129

Abstract Article PDF–858K

Select item 266804412.

Asymmetric Lower-Limb Malformations in Individuals with Homeobox PITX1 Gene Mutation

Christina A. Gurnett, Farhang Alaee, Lisa M. Kruse, David M. Desruisseau, Jacqueline T. Hecht, Carol A. Wise, Anne M. Bowcock, Matthew B. Dobbs

Am J Hum Genet. 2008 Nov 17; 83(5): 616–622. doi: 10.1016/j.ajhg.2008.10.004

PMCID:: PMC2668044

Abstract Article PDF–531K

Select item 969010113.

What Is the Exact Contribution of PITX1 and TBX4 Genes in Clubfoot Development? An Italian Study

Anna Monica Bianco, Giulia Ragusa, Valentina Di Carlo, Flavio Faletra, Mariateresa Di Stazio, Costantina Racano, Giovanni Trisolino, Stefania Cappellani, Maurizio De Pellegrin, Ignazio d’Addetta, Giuseppe Carluccio, Sergio Monforte, Antonio Andreacchio, Daniela Dibello, Adamo P. d’Adamo

Genes (Basel) 2022 Nov; 13(11): 1958. Published online 2022 Oct 27. doi: 10.3390/genes13111958

PMCID:: PMC9690101

Abstract Article PDF–246K

Select item 752163714.

The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene

Jeong Su Byun, Mihee Oh, Seonha Lee, Jung-Eun Gil, Yeajin Mo, Bonsu Ku, Won-Kon Kim, Kyoung-Jin Oh, Eun-Woo Lee, Kwang-Hee Bae, Sang Chul Lee, Baek-Soo Han

J Biol Chem. 2020 Sep 25; 295(39): 13677–13690. Published online 2020 Aug 5. doi: 10.1074/jbc.RA120.013352

PMCID:: PMC7521637

Abstract Article PDF–3.4M

Select item 676184715.

Retinoic Acid Promotes Retinoic Acid Signaling by Suppression of Pitx1 In Tendon Cells: A Possible Mechanism of a Clubfoot-Like Phenotype Induced by Retinoic Acid

Xiang Zhao, Xuan Yang

Med Sci Monit. 2019; 25: 6980–6989. Published online 2019 Sep 17. doi: 10.12659/MSM.917740

PMCID:: PMC6761847

Abstract Article PDF–1.9M

Select item 348464716.

Homeotic Arm-to-Leg Transformation Associated with Genomic Rearrangements at the PITX1 Locus

Malte Spielmann, Francesco Brancati, Peter M. Krawitz, Peter N. Robinson, Daniel M. Ibrahim, Martin Franke, Jochen Hecht, Silke Lohan, Katarina Dathe, Anna Maria Nardone, Paola Ferrari, Antonio Landi, Lars Wittler, Bernd Timmermann, Danny Chan, Ulrich Mennen, Eva Klopocki, Stefan Mundlos

Am J Hum Genet. 2012 Oct 5; 91(4): 629–635. doi: 10.1016/j.ajhg.2012.08.014