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Select item 103603971.

Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease

Sumudu S C Amarasekera, Daniella H Hock, Nicole J Lake, Sarah E Calvo, Sabine W Grønborg, Emma I Krzesinski, David J Amor, Michael C Fahey, Cas Simons, Flemming Wibrand, Vamsi K Mootha, Monkol Lek, Sebastian Lunke, Zornitza Stark, Elsebet Østergaard, John Christodoulou, David R Thorburn, David A Stroud, Alison G Compton

Hum Mol Genet. 2023 Aug 1; 32(15): 2441–2454. Published online 2023 May 3. doi: 10.1093/hmg/ddad069

PMCID:: PMC10360397

Abstract Article PDF–1.6M

Select item 82101622.

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells

Muhammad Sohail, Lulzim Shkreta, Johanne Toutant, Safwat Rabea, Jean-Philippe Babeu, Caroline Huard, Jasmin Coulombe-Huntington, Aurélie Delannoy, Morgane Placet, Sameh Geha, Fernand-Pierre Gendron, François Boudreau, Mike Tyers, David S Grierson, Benoit Chabot

NAR Cancer. 2021 Jun; 3(2): zcab019. Published online 2021 May 25. doi: 10.1093/narcan/zcab019

PMCID:: PMC8210162

Abstract Article PDF–5.8M

Select item 56330773.

Structures of the human mitochondrial ribosome in native states of assembly

Alan Brown, Sorbhi Rathore, Dari Kimanius, Shintaro Aibara, Xiao-chen Bai, Joanna Rorbach, Alexey Amunts, V. Ramakrishnan

Nat Struct Mol Biol. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Nat Struct Mol Biol. 2017 Oct; 24(10): 866–869. Published online 2017 Sep 11. doi: 10.1038/nsmb.3464

PMCID:: PMC5633077

Abstract Article PDF–1.4M

Select item 58280884.

Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics

Chunyu Hou, Yuan Li, Huiqin Liu, Mengjiao Dang, Guoxuan Qin, Ning Zhang, Ruibing Chen

Proteome Sci. 2018; 16: 5. Published online 2018 Feb 26. doi: 10.1186/s12953-018-0134-8

PMCID:: PMC5828088

Abstract Article PDF–2.5M

Select item 33472345.

Biochemical and Phosphoproteomic Analysis of the Helix-Loop-Helix Protein E47

Robert Teachenor, Kristina Beck, Lilyan Y. T. Wright, Zhouxin Shen, Steven P. Briggs, Cornelis Murre

Mol Cell Biol. 2012 May; 32(9): 1671–1682. doi: 10.1128/MCB.06452-11

PMCID:: PMC3347234

Abstract Article PDF–2.0M

Select item 66996236.

The human regulatory protein Ki-1/57 is a target of SUMOylation and affects PML nuclear bodies formation

Ângela Saito, Edmarcia E. Souza, Fernanda C. Costa, Gabriela V. Meirelles, Kaliandra A. Gonçalves, Marcos T. Santos, Gustavo C. Bressan, Mark E. McComb, Catherine E. Costello, Stephen A. Whelan, Jörg Kobarg

J Proteome Res. Author manuscript; available in PMC 2019 Aug 19.

Published in final edited form as: J Proteome Res. 2017 Sep 1; 16(9): 3147–3157. Published online 2017 Jul 31. doi: 10.1021/acs.jproteome.7b00001

PMCID:: PMC6699623

Abstract Article PDF–1.0M

Select item 42460627.

Structure of the large ribosomal subunit from human mitochondria

Alan Brown, Alexey Amunts, Xiao-chen Bai, Yoichiro Sugimoto, Patricia C. Edwards, Garib Murshudov, Sjors H. W. Scheres, V. Ramakrishnan

Science. Author manuscript; available in PMC 2015 May 7.

Published in final edited form as: Science. 2014 Nov 7; 346(6210): 718–722. Published online 2014 Oct 2. doi: 10.1126/science.1258026

PMCID:: PMC4246062

Abstract Article PDF–1.6M

Select item 66463878.

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

Kerrie-Ann McMahon, Yeping Wu, Yann Gambin, Emma Sierecki, Vikas A. Tillu, Thomas Hall, Nick Martel, Satomi Okano, Shayli Varasteh Moradi, Jayde E. Ruelcke, Charles Ferguson, Alpha S. Yap, Kirill Alexandrov, Michelle M. Hill, Robert G. Parton

Nat Commun. 2019; 10: 3279. Published online 2019 Jul 22. doi: 10.1038/s41467-019-11111-1

PMCID:: PMC6646387

Abstract Article PDF–7.0M

Select item 51049419.

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells

Christian H. Gabriel, Fridolin Gross, Martin Karl, Heike Stephanowitz, Anna Floriane Hennig, Melanie Weber, Stefanie Gryzik, Ivo Bachmann, Katharina Hecklau, Jürgen Wienands, Johannes Schuchhardt, Hanspeter Herzel, Andreas Radbruch, Eberhard Krause, Ria Baumgrass

J Biol Chem. 2016 Nov 11; 291(46): 24172–24187. Published online 2016 Sep 16. doi: 10.1074/jbc.M116.739326

PMCID:: PMC5104941

Abstract Article PDF–3.6M

Select item 460415510.

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy

Bethany L. Johnson-Kerner, Alejandro Garcia Diaz, Sean Ekins, Hynek Wichterle

PLoS One. 2015; 10(10): e0140157. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0140157

PMCID:: PMC4604155

Abstract Article PDF–2.9M

Select item 593507411.

Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches

Nathan Zuzow, Arit Ghosh, Marilyn Leonard, Jeffrey Liao, Bing Yang, Eric J. Bennett

Mol Biol Cell. 2018 May 15; 29(10): 1258–1269. doi: 10.1091/mbc.E17-12-0714

PMCID:: PMC5935074

Abstract Article PDF–5.9M

Select item 284527112.

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

Ricarda Richter, Joanna Rorbach, Aleksandra Pajak, Paul M Smith, Hans J Wessels, Martijn A Huynen, Jan A Smeitink, Robert N Lightowlers, Zofia M Chrzanowska-Lightowlers

EMBO J. 2010 Mar 17; 29(6): 1116–1125. Published online 2010 Feb 25. doi: 10.1038/emboj.2010.14

PMCID:: PMC2845271

Abstract Article PDF–1.3M

Select item 818479613.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Abstract Article PDF–2.4M

Select item 328162814.

Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein

Xiangbing Meng, Danlin Zhu, Shujie Yang, Xinjun Wang, Zhi Xiong, Yuping Zhang, Pavla Brachova, Kimberly K. Leslie

J Biol Chem. 2012 Feb 10; 287(7): 4485–4491. Published online 2011 Dec 23. doi: 10.1074/jbc.C111.291518

PMCID:: PMC3281628

Abstract Article PDF–2.0M

Select item 702912315.

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

Yuanming He, Siyu Wang, Jiefei Tong, Shuoyi Jiang, Ye Yang, Zubin Zhang, Yujia Xu, Yuanying Zeng, Biyin Cao, Michael F. Moran, Xinliang Mao

J Biol Chem. 2020 Feb 14; 295(7): 2084–2096. Published online 2019 Dec 10. doi: 10.1074/jbc.RA119.010724

PMCID:: PMC7029123

Abstract Article PDF–3.6M

Select item 998681716.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 603747717.

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation

Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter

eLife. 2018; 7: e35528. Published online 2018 Jun 18. doi: 10.7554/eLife.35528

PMCID:: PMC6037477

Abstract Article PDF–1.5M

Select item 649858518.

Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes

Jee Hoon Lee, Ji-hye Han, Hyunmi Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou

Acta Neuropathol Commun. 2019; 7: 68. Published online 2019 May 2. doi: 10.1186/s40478-019-0716-4

PMCID:: PMC6498585

Abstract Article PDF–6.9M

Select item 364706519.

The SOX2-Interactome in Brain Cancer Cells Identifies the Requirement of MSI2 and USP9X for the Growth of Brain Tumor Cells

Jesse L. Cox, Phillip J. Wilder, Joshua M. Gilmore, Erin L. Wuebben, Michael P. Washburn, Angie Rizzino

PLoS One. 2013; 8(5): e62857. Published online 2013 May 7. doi: 10.1371/journal.pone.0062857

PMCID:: PMC3647065

Abstract Article PDF–5.0M

Select item 422778620.

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling

Rajat Roy, Danielle Durie, Hui Li, Bing-Qian Liu, John Mark Skehel, Francesco Mauri, Lucia Veronica Cuorvo, Mattia Barbareschi, Lin Guo, Martin Holcik, Michael J. Seckl, Olivier E. Pardo

Nucleic Acids Res. 2014 Nov 10; 42(20): 12483–12497. Published online 2014 Oct 16. doi: 10.1093/nar/gku953

Correction in:: Nucleic Acids Res. 2024 Jul 22; 52(13): 8034.

PMCID:: PMC4227786

Abstract Article PDF–688K

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