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Select item 82616211.

Interference with KCNJ2 inhibits proliferation, migration and EMT progression of apillary thyroid carcinoma cells by upregulating GNG2 expression

Siyuan Chen, Miaoming Huang, Xiarong Hu

Mol Med Rep. 2021 Sep; 24(3): 622. Published online 2021 Jun 30. doi: 10.3892/mmr.2021.12261

PMCID:: PMC8261621

Abstract Article PDF–11M

Select item 34341802.

Topography of Gng2- and NetrinG2-Expression Suggests an Insular Origin of the Human Claustrum

Andrea Pirone, Bruno Cozzi, Larry Edelstein, Antonella Peruffo, Carla Lenzi, Francesca Quilici, Rita Antonini, Maura Castagna

PLoS One. 2012; 7(9): e44745. Published online 2012 Sep 5. doi: 10.1371/journal.pone.0044745

PMCID:: PMC3434180

Abstract Article PDF–518K

Select item 74156633.

Structure of a D₂ dopamine receptor-G protein complex in a lipid membrane

Jie Yin, Kuang-Yui M. Chen, Mary J. Clark, Mahdi Hijazi, Punita Kumari, Xiao-chen Bai, Roger K. Sunahara, Patrick Barth, Daniel M. Rosenbaum

Nature. Author manuscript; available in PMC 2020 Dec 11.

Published in final edited form as: Nature. 2020 Aug; 584(7819): 125–129. Published online 2020 Jun 11. doi: 10.1038/s41586-020-2379-5

PMCID:: PMC7415663

Abstract Article PDF–6.3M

Select item 58324414.

Phase-plate cryo-EM structure of a class B GPCR-G protein complex

Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia, Yan Zhang, Alisa Glukhova, Jeffrey Tarrasch, David M Thal, Sebastian G. B. Furness, George Christopoulos, Thomas Coudrat, Radostin Danev, Wolfgang Baumeister, Laurence J. Miller, Arthur Christopoulos, Brian K Kobilka, Denise Wootten, Georgios Skiniotis, Patrick M. Sexton

Nature. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Nature. 2017 Jun 1; 546(7656): 118–123. Published online 2017 Apr 24. doi: 10.1038/nature22327

PMCID:: PMC5832441

Abstract Article PDF–2.4M

Select item 46546285.

X-ray structure of the mammalian GIRK2 – ß? G protein complex

Matthew R. Whorton, Roderick MacKinnon

Nature. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Nature. 2013 Jun 13; 498(7453): 190–197. Published online 2013 Jun 5. doi: 10.1038/nature12241

PMCID:: PMC4654628

Abstract Article PDF–2.1M

Select item 44433606.

G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity

Jennifer B. Stott, Oleksandr V. Povstyan, Georgina Carr, Vincenzo Barrese, Iain A. Greenwood

Proc Natl Acad Sci U S A. 2015 May 19; 112(20): 6497–6502. Published online 2015 May 4. doi: 10.1073/pnas.1418605112

PMCID:: PMC4443360

Abstract Article PDF–1.2M

Select item 31417747.

Gβγ subunits inhibit Epac-induced melanoma cell migration

Erdene Baljinnyam, Masanari Umemura, Mariana S De Lorenzo, Lai-Hua Xie, Martha Nowycky, Mizuka Iwatsubo, Suzie Chen, James S Goydos, Kousaku Iwatsubo

BMC Cancer. 2011; 11: 256. Published online 2011 Jun 17. doi: 10.1186/1471-2407-11-256

PMCID:: PMC3141774

Abstract Article PDF–823K

Select item 28295478.

Scanning mutagenesis of the I-II loop of the Ca_v2.2 calcium channel identifies residues Arginine 376 and Valine 416 as molecular determinants of voltage dependent G protein inhibition

Hugo W Tedford, Alexandra E Kisilevsky, Lucienne B Vieira, Diego Varela, Lina Chen, Gerald W Zamponi

Mol Brain. 2010; 3: 6. Published online 2010 Feb 3. doi: 10.1186/1756-6606-3-6

PMCID:: PMC2829547

Abstract Article PDF–627K

Select item 23425129.

The familial hemiplegic migraine mutation R192q reduces G-protein-mediated inhibition of p/q-type (Ca_v2.1) calcium channels expressed in human embryonic kidney cells

Karim Melliti, Manfred Grabner, Guy R Seabrook

J Physiol. 2003 Jan 15; 546(Pt 2): 337–347. Published online 2002 Nov 22. doi: 10.1113/jphysiol.2002.026716

PMCID:: PMC2342512

Abstract Article PDF–275K

Select item 274564710.

β-arrestin1 interacts with the G protein subunits β1γ2 and promotes β1γ2-dependent Akt signaling for NF-κB activation

Ming Yang, Rong L. He, Jeffrey L. Benovic, Richard D. Ye

Biochem J. Author manuscript; available in PMC 2009 Sep 17.

Published in final edited form as: Biochem J. 2009 Jan 1; 417(1): 287–296. doi: 10.1042/BJ20081561

PMCID:: PMC2745647

Abstract Article PDF–1.2M

Select item 407681311.

A genome-wide gene–environment interaction analysis for tobacco smoke and lung cancer susceptibility

Ruyang Zhang, Minjie Chu, Yang Zhao, Chen Wu, Huan Guo, Yongyong Shi, Juncheng Dai, Yongyue Wei, Guangfu Jin, Hongxia Ma, Jing Dong, Honggang Yi, Jianling Bai, Jianhang Gong, Chongqi Sun, Meng Zhu, Tangchun Wu, Zhibin Hu, Dongxin Lin, Hongbing Shen, Feng Chen

Carcinogenesis. 2014 Jul; 35(7): 1528–1535. Published online 2014 Mar 22. doi: 10.1093/carcin/bgu076