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Select item 93691621.

Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities

David A. Doetsch, Salim Ansari, Ole Jensen, Lukas Gebauer, Christof Dücker, Jürgen Brockmöller, Alexandra Sachkova

Int J Mol Sci. 2022 Aug; 23(15): 8430. Published online 2022 Jul 29. doi: 10.3390/ijms23158430

PMCID:: PMC9369162

Abstract Article PDF–1.4M

Select item 84584392.

Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress

Alexander G. Stepchenko, Tatiana N. Portseva, Ivan A. Glukhov, Alina P. Kotnova, Bella M. Lyanova, Sofia G. Georgieva, Elizaveta V. Pankratova

Sci Rep. 2021; 11: 18808. Published online 2021 Sep 22. doi: 10.1038/s41598-021-98323-y

PMCID:: PMC8458439

Abstract Article PDF–1.8M

Select item 74233733.

Collective invasion of glioma cells through OCT1 signalling and interaction with reactive astrocytes after surgery

Yangjin Kim, Donggu Lee, Sean Lawler

Philos Trans R Soc Lond B Biol Sci. 2020 Sep 14; 375(1807): 20190390. Published online 2020 Jul 27. doi: 10.1098/rstb.2019.0390

PMCID:: PMC7423373

Abstract Article PDF–2.2M

Select item 60574584.

The regulatory interplay between Oct-1 isoforms contributes to hematopoiesis and the isoforms imbalance correlates with a malignant transformation of B cells

Elizaveta V. Pankratova, Alexander G. Stepchenko, Irina D. Krylova, Tatiana N. Portseva, Sofia G. Georgieva

Oncotarget. 2018 Jul 6; 9(52): 29892–29905. Published online 2018 Jul 6. doi: 10.18632/oncotarget.25648

PMCID:: PMC6057458

Abstract Article PDF–5.6M

Select item 55914625.

OCT1 genetic variants are associated with postoperative morphine-related adverse effects in children

Rajiv Balyan, Xue Zhang, Vidya Chidambaran, Lisa J Martin, Tomoyuki Mizuno, Tsuyoshi Fukuda, Alexander A Vinks, Senthilkumar Sadhasivam

Pharmacogenomics. 2017 May; 18(7): 621–629. Published online 2017 May 4. doi: 10.2217/pgs-2017-0002

PMCID:: PMC5591462

Abstract Article PDF–1.0M

Select item 55464646.

POU2F1 over-expression correlates with poor prognoses and promotes cell growth and epithelial-to-mesenchymal transition in hepatocellular carcinoma

Yonghao Zhong, Hongyang Huang, Min Chen, Jinzhou Huang, Qingxia Wu, Guang-Rong Yan, De Chen

Oncotarget. 2017 Jul 4; 8(27): 44082–44095. Published online 2017 Apr 20. doi: 10.18632/oncotarget.17296

PMCID:: PMC5546464

Abstract Article PDF–8.4M

Select item 51005797.

Different N-terminal isoforms of Oct-1 control expression of distinct sets of genes and their high levels in Namalwa Burkitt's lymphoma cells affect a wide range of cellular processes

Elizaveta V. Pankratova, Alexander G. Stepchenko, Tatiana Portseva, Vladic A. Mogila, Sofia G. Georgieva

Nucleic Acids Res. 2016 Nov 2; 44(19): 9218–9230. Published online 2016 Jul 12. doi: 10.1093/nar/gkw623

PMCID:: PMC5100579

Abstract Article PDF–3.3M

Select item 48446388.

Elevated OCT1 participates in colon tumorigenesis and independently predicts poor prognoses of colorectal cancer patients

Yu-peng Wang, Guo-he Song, Jian Chen, Chao Xiao, Chao Li, Lin Zhong, Xing Sun, Zhao-wen Wang, Gui-long Deng, Fu-dong Yu, Ying-ming Xue, Hua-mei Tang, Zhi-hai Peng, Xiao-liang Wang

Tumour Biol. 2016 Mar; 37(3): 3247–3255. Published online 2015 Oct 4. doi: 10.1007/s13277-015-4080-0

PMCID:: PMC4844638

Abstract Article PDF–760K

Select item 47422879.

An Oct-1-based, feed-forward mechanism of apoptosis inhibited by co-culture with Raji B-cells: Towards a model of the cancer cell/B-cell microenvironment

Karoly Szekeres, Rudra Koul, James Mauro, Mark Lloyd, Joseph Johnson, George Blanck

Exp Mol Pathol. Author manuscript; available in PMC 2016 Feb 4.

Published in final edited form as: Exp Mol Pathol. 2014 Dec; 97(3): 585–589. Published online 2014 Sep 16. doi: 10.1016/j.yexmp.2014.09.010

PMCID:: PMC4742287

Abstract Article PDF–2.3M

Select item 458394810.

Genetic variants of OCT1 influence glycemic response to metformin in Han Chinese patients with type-2 diabetes mellitus in Shanghai

Yong Zhou, Weiwei Ye, Yi Wang, Zhikui Jiang, Xiangying Meng, Qian Xiao, Qian Zhao, Jian Yan

Int J Clin Exp Pathol. 2015; 8(8): 9533–9542. Published online 2015 Aug 1.

PMCID:: PMC4583948

Abstract Article PDF–334K

Select item 445271611.

Association of Organic Cation Transporter 1 with Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study

Tanja Dujic, Kaixin Zhou, Louise A Donnelly, Roger Tavendale, Colin NA Palmer, Ewan R Pearson

Diabetes. Author manuscript; available in PMC 2015 Jun 3.

Published in final edited form as: Diabetes. 2015 May; 64(5): 1786–1793. Published online 2014 Dec 15. doi: 10.2337/db14-1388

PMCID:: PMC4452716

Abstract Article PDF–335K

Select item 330651212.

Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1

Bor-Ruei Lin, Ven Natarajan

Gene. Author manuscript; available in PMC 2013 Apr 15.

Published in final edited form as: Gene. 2012 Apr 15; 497(2): 200–207. Published online 2012 Jan 28. doi: 10.1016/j.gene.2012.01.041

PMCID:: PMC3306512

Abstract Article PDF–1.9M

Select item 310729313.

Intra- and intermolecular translocation of the bi-domain transcription factor Oct1 characterized by liquid crystal and paramagnetic NMR

Yuki Takayama, G. Marius Clore

Proc Natl Acad Sci U S A. 2011 May 31; 108(22): E169-E176. Published online 2011 May 9. doi: 10.1073/pnas.1100050108

PMCID:: PMC3107293

Abstract Article PDF–2.4M

Select item 303168814.

OCT-1 function varies with cell lineage but is not influenced by BCR-ABL

Jane R. Engler, Andrew C.W. Zannettino, Charles G. Bailey, John E.J. Rasko, Timothy P. Hughes, Deborah L. White

Haematologica. 2011 Feb; 96(2): 213–220. Published online 2010 Oct 22. doi: 10.3324/haematol.2010.033290

PMCID:: PMC3031688

Abstract Article PDF–1.3M

Select item 301216815.

OCT1 Expression in Adipocytes Could Contribute to Increased Metformin Action in Obese Subjects

José María Moreno-Navarrete, Francisco J. Ortega, José-Ignacio Rodríguez-Hermosa, Mònica Sabater, Gerard Pardo, Wifredo Ricart, José Manuel Fernández-Real

Diabetes. 2011 Jan; 60(1): 168–176. Published online 2010 Oct 18. doi: 10.2337/db10-0805

PMCID:: PMC3012168

Abstract Article PDF–635K

Select item 254454616.

Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1

Michaeleen Doucleff, G. Marius Clore

Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37): 13871–13876. Published online 2008 Sep 4. doi: 10.1073/pnas.0805050105

PMCID:: PMC2544546

Abstract Article PDF–519K

Select item 186808517.

Expression of B-Lymphocyte-Associated Transcription Factors in Human T-Cell Neoplasms

Teresa Marafioti, Stefano Ascani, Karen Pulford, Elena Sabattini, Milena Piccioli, Margaret Jones, Pier Luigi Zinzani, Georges Delsol, David Y. Mason, Stefano A. Pileri

Am J Pathol. 2003 Mar; 162(3): 861–871. doi: 10.1016/S0002-9440(10)63882-5

PMCID:: PMC1868085

Abstract Article PDF–1.5M

Select item 881934318.

Hypoxia‐inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy

Kuo‐Hao Ho, Chwen‐Ming Shih, Ann‐Jeng Liu, Ku‐Chung Chen

Cancer Sci. 2022 Feb; 113(2): 540–552. Published online 2021 Dec 23. doi: 10.1111/cas.15240

PMCID:: PMC8819343

Abstract Article PDF–2.9M

Select item 858402019.

OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH

Takuya Ogura, Kotaro Azuma, Junichiro Sato, Keiichi Kinowaki, Ken-Ichi Takayama, Toshihiko Takeiwa, Hidetaka Kawabata, Satoshi Inoue

Int J Mol Sci. 2021 Nov; 22(21): 11505. Published online 2021 Oct 25. doi: 10.3390/ijms222111505

PMCID:: PMC8584020

Abstract Article PDF–1.4M

Select item 767054820.

Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia

Jillian L. Jafek, Arvind Shakya, Pei-Yi Tai, Andrea Ibarra, Heejoo Kim, Jessica Maddox, Jeffrey Chumley, Gerald J. Spangrude, Rodney R. Miles, Todd W. Kelley, Dean Tantin

Exp Hematol. Author manuscript; available in PMC 2020 Nov 17.

Published in final edited form as: Exp Hematol. 2019 Aug; 76: 38–48.e2. Published online 2019 Jul 8. doi: 10.1016/j.exphem.2019.07.002