PMC Links for Gene (Select 54855) - PMC

Select item 104492971.

FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma

Weilong Zhang, Chaoling Wu, Shuang Geng, Jing Wang, Changjian Yan, Xiannian Zhang, Jia-jia Zhang, Fan Wu, Yuhong Pang, Yuping Zhong, Jianbin Wang, Wei Fu, Xin Huang, Wenming Wang, Xiaoqing Lyu, Yanyi Huang, Hongmei Jing

Aging (Albany NY) 2023 May 15; 15(9): 3644–3677. Published online 2023 May 6. doi: 10.18632/aging.204697

PMCID:: PMC10449297

Abstract Article PDF–4.1M

Select item 72261862.

Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells

Jo Kanasugi, Ichiro Hanamura, Akinobu Ota, Sivasundaram Karnan, Vu Quang Lam, Shohei Mizuno, Md Wahiduzzaman, Md Lutfur Rahman, Toshinori Hyodo, Hiroyuki Konishi, Shinobu Tsuzuki, Yoshitaka Hosokawa, Akiyoshi Takami

Cancer Sci. 2020 May; 111(5): 1663–1675. Published online 2020 Apr 9. doi: 10.1111/cas.14386

PMCID:: PMC7226186

Abstract Article PDF–1.8M

Select item 71714233.

FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma

Ana Belén Herrero, Dalia Quwaider, Luis Antonio Corchete, Maria Victoria Mateos, Ramón García‐Sanz, Norma C. Gutiérrez

J Cell Mol Med. 2020 Apr; 24(7): 4171–4182. Published online 2020 Mar 6. doi: 10.1111/jcmm.15078

PMCID:: PMC7171423

Abstract Article PDF–1.6M

Select item 55865974.

Loss of FAM46C promotes cell survival in myeloma

Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Patrick Jedlowski, Xuewei Wang, K. Martin Kortüm, Moulun Luo, Jonathan M. Ahmann, Esteban Braggio, A. Keith Stewart

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4317–4327. Published online 2017 Jun 15. doi: 10.1158/0008-5472.CAN-16-3011

PMCID:: PMC5586597

Abstract Article PDF–1.3M

Select item 54282585.

FAM46C is critical for the anti-proliferation and pro-apoptotic effects of norcantharidin in hepatocellular carcinoma cells

Qiao-Yan Zhang, Xiao-Qiang Yue, Yi-Ping Jiang, Ting Han, Hai-Liang Xin

Sci Rep. 2017; 7: 396. Published online 2017 Mar 24. doi: 10.1038/s41598-017-00313-6

Correction in:: Sci Rep. 2017; 7: 17576.

PMCID:: PMC5428258

Abstract Article PDF–5.3M

Select item 82861426.

Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C

Hong Zhang, Shi‐Hui Zhang, Jia‐Li Hu, Yu‐Tong Wu, Xiao‐Yan Ma, Yang Chen, Bing Yu, Shuang Liao, Huilin Huang, Song Gao

Cancer Commun (Lond) 2021 Jul; 41(7): 615–630. Published online 2021 May 28. doi: 10.1002/cac2.12163

PMCID:: PMC8286142

Abstract Article PDF–4.1M

Select item 74318437.

FAM46C/TENT5C functions as a tumor suppressor through inhibition of Plk4 activity

Karineh Kazazian, Yosr Haffani, Deanna Ng, Chae Min Michelle Lee, Wendy Johnston, Minji Kim, Roland Xu, Karina Pacholzyk, Francis Si-Wah Zih, Julie Tan, Alannah Smrke, Aaron Pollett, Hannah Sun-Tsi Wu, Carol Jane Swallow

Commun Biol. 2020; 3: 448. Published online 2020 Aug 17. doi: 10.1038/s42003-020-01161-3

PMCID:: PMC7431843

Abstract Article PDF–3.0M

Select item 70496888.

FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells

Jia-Li Hu, He Liang, Hong Zhang, Ming-Zhu Yang, Wei Sun, Peng Zhang, Li Luo, Jian-Xiong Feng, Huajun Bai, Fang Liu, Tianpeng Zhang, Jin-Yu Yang, Qingsong Gao, Yongkang Long, Xiao-Yan Ma, Yang Chen, Qian Zhong, Bing Yu, Shuang Liao, Yongbo Wang, Yong Zhao, Mu-Sheng Zeng, Nan Cao, Jichang Wang, Wei Chen, Huang-Tian Yang, Song Gao

Nucleic Acids Res. 2020 Mar 18; 48(5): 2733–2748. Published online 2020 Feb 3. doi: 10.1093/nar/gkaa049

PMCID:: PMC7049688

Abstract Article PDF–5.5M

Select item 57518839.

Mapping of Chromosome 1p Deletions in Myeloma Identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being Genes in Regions Associated with Adverse Survival

Kevin D. Boyd, Fiona M. Ross, Brian A. Walker, Christopher P. Wardell, William J. Tapper, Laura Chiecchio, GianPaolo Dagrada, Zoe J Konn, Walter M. Gregory, Graham H Jackson, J Anthony Child, Faith E. Davies, Gareth J. Morgan

Clin Cancer Res. Author manuscript; available in PMC 2018 Jan 3.

Published in final edited form as: Clin Cancer Res. 2011 Dec 15; 17(24): 7776–7784. Published online 2011 Oct 12. doi: 10.1158/1078-0432.CCR-11-1791

PMCID:: PMC5751883

Abstract Article PDF–1.5M

Select item 605354010.

3′ RNA Uridylation in Epitranscriptomics, Gene Regulation, and Disease

Miriam R. Menezes, Julien Balzeau, John P. Hagan

Front Mol Biosci. 2018; 5: 61. Published online 2018 Jul 13. doi: 10.3389/fmolb.2018.00061

PMCID:: PMC6053540

Abstract Article PDF–2.2M

Select item 741556611.

Structural and functional analyses of the FAM46C/Plk4 complex

Hua Chen, Defen Lu, Guijun Shang, Guoming Gao, Xuewu Zhang

Structure. Author manuscript; available in PMC 2021 Aug 4.

Published in final edited form as: Structure. 2020 Aug 4; 28(8): 910–921.e4. Published online 2020 May 19. doi: 10.1016/j.str.2020.04.023

PMCID:: PMC7415566

Abstract Article PDF–2.0M

Select item 560699712.

The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma

Seweryn Mroczek, Justyna Chlebowska, Tomasz M. Kuliński, Olga Gewartowska, Jakub Gruchota, Dominik Cysewski, Vladyslava Liudkovska, Ewa Borsuk, Dominika Nowis, Andrzej Dziembowski

Nat Commun. 2017; 8: 619. Published online 2017 Sep 20. doi: 10.1038/s41467-017-00578-5

PMCID:: PMC5606997

Abstract Article PDF–2.3M

Select item 766637113.

TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination

Li Xing, Xiaolong Tang, Kaikai Wu, Xiong Huang, Yi Yi, Jinliang Huan

Mol Ther Nucleic Acids. 2020 Dec 4; 22: 910–923. Published online 2020 Oct 15. doi: 10.1016/j.omtn.2020.10.012

PMCID:: PMC7666371

Abstract Article PDF–4.6M

Select item 340958814.

A diverse array of gene products are effectors of the type I interferon antiviral response

John W. Schoggins, Sam J. Wilson, Maryline Panis, Mary Y. Murphy, Christopher T. Jones, Paul Bieniasz, Charles M. Rice

Nature. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Nature. 2011 Apr 28; 472(7344): 481–485. Published online 2011 Apr 10. doi: 10.1038/nature09907

PMCID:: PMC3409588

Abstract Article PDF–939K

Select item 399653715.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 268304716.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 426658817.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050