PMC Links for Gene (Select 5538) - PMC

Vito W. Rebecca, Michael C. Nicastri, Colin Fennelly, Cynthia I. Chude, Julie S. Barber-Rotenberg, Amruta Ronghe, Quentin McAfee, Noel P. McLaughlin, Gao Zhang, Aaron R. Goldman, Rani Ojha, Shengfu Piao, Estela Noguera-Ortega, Alessandra Martorella, Gretchen M. Alicea, Jennifer J. Lee, Lynn M. Schuchter, Xiaowei Xu, Meenhard Herlyn, Ronen Marmorstein, Phyllis A. Gimotty, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi

Cancer Discov. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Cancer Discov. 2019 Feb; 9(2): 220–229. Published online 2018 Nov 15. doi: 10.1158/2159-8290.CD-18-0706

PMCID:: PMC6368875

Abstract Article PDF–1.5M

Select item 47017224.

Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)

Michal Segal-Salto, Tamar Sapir, Orly Reiner

PLoS One. 2016; 11(1): e0146466. Published online 2016 Jan 5. doi: 10.1371/journal.pone.0146466

PMCID:: PMC4701722

Abstract Article PDF–5.2M

Select item 32201915.

Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis in cultured cells from INCL patients

Chinmoy Sarkar, Zhongjian Zhang, Anil B. Mukherjee

Mol Genet Metab. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Mol Genet Metab. 2011 Nov 1; 104(3): 338–345. doi: 10.1016/j.ymgme.2011.05.021

PMCID:: PMC3220191

Abstract Article PDF–1.5M

Select item 5088946.

Molecular genetics of palmitoyl-protein thioesterase deficiency in the U.S.

A K Das, C H Becerra, W Yi, J Y Lu, A N Siakotos, K E Wisniewski, S L Hofmann

J Clin Invest. 1998 Jul 15; 102(2): 361–370. doi: 10.1172/JCI3112

PMCID:: PMC508894

Summary PDF–535K

Select item 395337.

Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis.

C M Crews, W S Lane, S L Schreiber

Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9): 4316–4319. doi: 10.1073/pnas.93.9.4316

PMCID:: PMC39533

Summary Page Browse PDF–1005K

Select item 62920898.

Batten disease: biochemical and molecular characterization revealing novel PPT1 and TPP1 gene mutations in Indian patients

Jayesh Sheth, Mehul Mistri, Riddhi Bhavsar, Dhairya Pancholi, Mahesh Kamate, Neerja Gupta, Madhulika Kabra, Sanjiv Mehta, Sheela Nampoothiri, Arpita Thakker, Vivek Jain, Raju Shah, Frenny Sheth

BMC Neurol. 2018; 18: 203. Published online 2018 Dec 12. doi: 10.1186/s12883-018-1206-1

PMCID:: PMC6292089

Abstract Article PDF–2.2M

Select item 58919779.

Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses

Ni Sima, Rong Li, Wei Huang, Miao Xu, Jeanette Beers, Jizhong Zou, Steven Titus, Elizabeth A. Ottinger, Juan J. Marugan, Xing Xie, Wei Zheng

Orphanet J Rare Dis. 2018; 13: 54. Published online 2018 Apr 10. doi: 10.1186/s13023-018-0798-2

PMCID:: PMC5891977

Abstract Article PDF–4.6M

Select item 583397810.

A unified approach to targeting the lysosome’s degradative and growth signaling roles

Vito W. Rebecca, Michael C. Nicastri, Noel McLaughlin, Colin Fennelly, Quentin McAfee, Amruta Ronghe, Michel Nofal, Chun-Yan Lim, Eric Witze, Cynthia I. Chude, Gao Zhang, Gretchen M. Alicea, Shengfu Piao, Sengottuvelan Murugan, Rani Ojha, Samuel M. Levi, Zhi Wei, Julie S. Barber-Rotenberg, Maureen E. Murphy, Gordon B. Mills, Yiling Lu, Joshua Rabinowitz, Ronen Marmorstein, Qin Liu, Shujing Liu, Xiaowei Xu, Meenhard Herlyn, Roberto Zoncu, Donita C. Brady, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi

Cancer Discov. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Cancer Discov. 2017 Nov; 7(11): 1266–1283. Published online 2017 Sep 12. doi: 10.1158/2159-8290.CD-17-0741

PMCID:: PMC5833978

Abstract Article PDF–960K

Select item 572400711.

Lactate-mediated mitoribosomal defects impair mitochondrial oxidative phosphorylation and promote hepatoma cell invasiveness

Young-Kyoung Lee, Jin J. Lim, Un-woo Jeoun, Seongki Min, Eun-beom Lee, So Mee Kwon, Changhan Lee, Gyesoon Yoon

J Biol Chem. 2017 Dec 8; 292(49): 20208–20217. Published online 2017 Oct 4. doi: 10.1074/jbc.M117.809012

PMCID:: PMC5724007

Abstract Article PDF–1.6M

Select item 410269912.

Identification of palmitoyl protein thioesterase 1 in human THP-1 monocytes/macrophages and characterization of unique biochemical activities for this enzyme

Ran Wang, Abdolsamad Borazjani, Anberitha T. Matthews, Lee C. Mangum, Mariola J. Edelmann, Matthew K. Ross

Biochemistry. Author manuscript; available in PMC 2014 Jul 18.

Published in final edited form as: Biochemistry. 2013 Oct 29; 52(43): 7559–7574. Published online 2013 Oct 18. doi: 10.1021/bi401138s

PMCID:: PMC4102699

Abstract Article PDF–601K

Select item 251538113.

Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice

Sung-Jo Kim, Zhongjian Zhang, Chinmoy Sarkar, Pei-Chih Tsai, Yi-Ching Lee, Louis Dye, Anil B. Mukherjee

J Clin Invest. 2008 Sep 2; 118(9): 3075–3086. Published online 2008 Aug 14. doi: 10.1172/JCI33482

PMCID:: PMC2515381

Abstract Article PDF–1.1M

Select item 3833314.

Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.

J Y Lu, L A Verkruyse, S L Hofmann

Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19): 10046–10050. doi: 10.1073/pnas.93.19.10046

PMCID:: PMC38333

Summary Page Browse PDF–1.5M

Select item 45226815.

Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis.

E Hellsten, J Vesa, V M Olkkonen, A Jalanko, L Peltonen

EMBO J. 1996 Oct 1; 15(19): 5240–5245.

PMCID:: PMC452268

Summary Page Browse PDF–1.5M

Select item 934879716.

KCTD7 mutations impair the trafficking of lysosomal enzymes through CLN5 accumulation to cause neuronal ceroid lipofuscinoses

Yalan Wang, Xiaotong Cao, Pei Liu, Weijia Zeng, Rui Peng, Qing Shi, Kai Feng, Pingzhao Zhang, Huiru Sun, Chenji Wang, Hongyan Wang

Sci Adv. 2022 Aug; 8(31): eabm5578. Published online 2022 Aug 3. doi: 10.1126/sciadv.abm5578

PMCID:: PMC9348797

Abstract Article PDF–6.7M

Select item 279044317.

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

Annina Lyly, Carina von Schantz, Claudia Heine, Mia-Lisa Schmiedt, Tessa Sipilä, Anu Jalanko, Aija Kyttälä

BMC Cell Biol. 2009; 10: 83. Published online 2009 Nov 26. doi: 10.1186/1471-2121-10-83

PMCID:: PMC2790443

Abstract Article PDF–2.0M

Select item 451045418.

Quantitative analysis of PPT1 interactome in human neuroblastoma cells

Enzo Scifo, Agnieszka Szwajda, Rabah Soliymani, Francesco Pezzini, Marzia Bianchi, Arvydas Dapkunas, Janusz Dębski, Kristiina Uusi-Rauva, Michał Dadlez, Anne-Claude Gingras, Jaana Tyynelä, Alessandro Simonati, Anu Jalanko, Marc H. Baumann, Maciej Lalowski

Data Brief. 2015 Sep; 4: 207–216. Published online 2015 Jun 12. doi: 10.1016/j.dib.2015.05.016

PMCID:: PMC4510454

Abstract Article PDF–2.8M

Select item 603747719.

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation

Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter

eLife. 2018; 7: e35528. Published online 2018 Jun 18. doi: 10.7554/eLife.35528

PMCID:: PMC6037477

Abstract Article PDF–1.5M

Select item 886447220.

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network

Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang

Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195

PMCID:: PMC8864472

Abstract Article PDF–3.6M

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