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Items: 1 to 20 of 24

1.
The novel GATA1-interacting protein HES6 is an essential transcriptional cofactor for human erythropoiesis
Zi Wang, Pan Wang, Jieying Zhang, Han Gong, Xuchao Zhang, Jianhui Song, Ling Nie, Yuanliang Peng, Yanan Li, Hongling Peng, Yajuan Cui, Heng Li, Bin Hu, Jun Mi, Long Liang, Hong Liu, Ji Zhang, Mao Ye, Karina Yazdanbakhsh, Narla Mohandas, Xiuli An, Xu Han, Jing Liu
Nucleic Acids Res. 2023 Jun 9; 51(10): 4774–4790. Published online 2023 Mar 17. doi: 10.1093/nar/gkad167
PMCID:
PMC10250228
AbstractArticlePDF–8.5M
2.
Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease
Charlotte Pandiani, Thomas Strub, Nicolas Nottet, Yann Cheli, Giovanni Gambi, Karine Bille, Chrystel Husser, Mélanie Dalmasso, Guillaume Béranger, Sandra Lassalle, Virginie Magnone, Florence Pédeutour, Marie Irondelle, Célia Maschi, Sacha Nahon-Estève, Arnaud Martel, Jean-Pierre Caujolle, Paul Hofman, Kévin LeBrigand, Irwin Davidson, Stéphanie Baillif, Pascal Barbry, Robert Ballotti, Corine Bertolotto
Cell Death Differ. 2021 Jun; 28(6): 1990–2000. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00730-7
PMCID:
PMC8185008
AbstractArticlePDF–3.1M
3.
Overexpression of HES6 has prognostic value and promotes metastasis via the Wnt/β-catenin signaling pathway in colorectal cancer
Yuandong Xu, Xuejuan Liu, Huizhong Zhang, Ziyuan Zhu, Xianqiu Wu, Xiaobing Wu, Shuling Li, Libing Song, Xuehu Xu
Oncol Rep. 2018 Sep; 40(3): 1261–1274. Published online 2018 Jul 2. doi: 10.3892/or.2018.6539
Correction in:
Oncol Rep. 2022 May; 47(5): 98.
PMCID:
PMC6072391
AbstractArticlePDF–1.6M
4.
DOT1L-HES6 fusion drives androgen independent growth in prostate cancer
Matti Annala, Kati Kivinummi, Katri Leinonen, Joonas Tuominen, Wei Zhang, Tapio Visakorpi, Matti Nykter
EMBO Mol Med. 2014 Sep; 6(9): 1121–1123. Published online 2014 Jul 8. doi: 10.15252/emmm.201404210
PMCID:
PMC4197859
ArticlePDF–430K
5.
HES6 REVERSES NUCLEAR REPROGRAMMING OF INSULIN-PRODUCING CELLS FOLLOWING CELL FUSION
Andrew J. Ball, Annelie E. Abrahamsson, Björn Tyrberg, Pamela Itkin-Ansari, Fred Levine
Biochem Biophys Res Commun. Author manuscript; available in PMC 2008 Apr 6.
Published in final edited form as: Biochem Biophys Res Commun. 2007 Apr 6; 355(2): 331–337. Published online 2007 Feb 5. doi: 10.1016/j.bbrc.2007.01.153
PMCID:
PMC1852427
AbstractArticlePDF–789K
6.
HES6 promotes prostate cancer aggressiveness independently of Notch signalling
Filipe L F Carvalho, Luigi Marchionni, Anuj Gupta, Basheer A Kummangal, Edward M Schaeffer, Ashley E Ross, David M Berman
J Cell Mol Med. 2015 Jul; 19(7): 1624–1636. Published online 2015 Apr 12. doi: 10.1111/jcmm.12537
PMCID:
PMC4511360
AbstractArticlePDF–1.1M
7.
Hes-6, an inhibitor of Hes-1, is regulated by 17β-estradiol and promotes breast cancer cell proliferation
Johan Hartman, Eric W-F Lam, Jan-Åke Gustafsson, Anders Ström
Breast Cancer Res. 2009; 11(6): R79. Published online 2009 Nov 5. doi: 10.1186/bcr2446
PMCID:
PMC2815541
AbstractArticlePDF–964K
8.
HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program
Xiangming Gao, Tanya Chandra, Michel-Olivier Gratton, Isabelle Quélo, Josée Prud'homme, Stefano Stifani, René St-Arnaud
J Cell Biol. 2001 Sep 17; 154(6): 1161–1172. doi: 10.1083/jcb.200104058
PMCID:
PMC2150829
AbstractArticlePDF–344K
9.
ERCC5, HES6 and RORA are potential diagnostic markers of coronary artery disease
Zhifeng Bai, Yuanyuan Luo, Linyun Tian
FEBS Open Bio. 2022 Oct; 12(10): 1814–1827. Published online 2022 Aug 7. doi: 10.1002/2211-5463.13469
PMCID:
PMC9527589
AbstractArticlePDF–2.7M
10.
HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network
Antonio Ramos-Montoya, Alastair D Lamb, Roslin Russell, Thomas Carroll, Sarah Jurmeister, Nuria Galeano-Dalmau, Charlie E Massie, Joan Boren, Helene Bon, Vasiliki Theodorou, Maria Vias, Greg L Shaw, Naomi L Sharma, Helen Ross-Adams, Helen E Scott, Sarah L Vowler, William J Howat, Anne Y Warren, Richard F Wooster, Ian G Mills, David E Neal
EMBO Mol Med. 2014 May; 6(5): 651–661. Published online 2014 Apr 14. doi: 10.1002/emmm.201303581
PMCID:
PMC4023887
AbstractArticlePDF–1.6M
11.
Hes6 Promotes Cortical Neurogenesis and Inhibits Hes1 Transcription Repression Activity by Multiple Mechanisms
Michel-Olivier Gratton, Elena Torban, Stephanie Belanger Jasmin, Francesca M. Theriault, Michael S. German, Stefano Stifani
Mol Cell Biol. 2003 Oct; 23(19): 6922–6935. doi: 10.1128/MCB.23.19.6922-6935.2003
PMCID:
PMC193938
AbstractArticlePDF–491K
12.
SET8 promotes epithelial–mesenchymal transition and confers TWIST dual transcriptional activities
Fen Yang, Luyang Sun, Qian Li, Xiao Han, Liandi Lei, Hua Zhang, Yongfeng Shang
EMBO J. 2012 Jan 4; 31(1): 110–123. Published online 2011 Oct 7. doi: 10.1038/emboj.2011.364
PMCID:
PMC3252577
AbstractArticlePDF–2.6M
13.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat
Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54
PMCID:
PMC3817404
AbstractArticlePDF–13M
14.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
15.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
16.
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect
Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva
RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030
PMCID:
PMC4841607
AbstractArticlePDF–1.6M
17.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
18.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
19.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M

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