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Select item 98217101.

The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers

Cristina Zuccato, Lucia Carmela Cosenza, Matteo Zurlo, Giulia Breveglieri, Nicoletta Bianchi, Ilaria Lampronti, Jessica Gasparello, Chiara Scapoli, Monica Borgatti, Alessia Finotti, Roberto Gambari

Int J Mol Sci. 2023 Jan; 24(1): 776. Published online 2023 Jan 1. doi: 10.3390/ijms24010776

PMCID:: PMC9821710

Abstract Article PDF–1.6M

Select item 88099902.

Analysis of the role of Ly-1 antibody reactive in different cancer types

Linlin Chen, Congwen Jin, Hao Liu, Rongmei Feng, Zhengdong Li, Jiasheng Zhang

Bioengineered. 2021; 12(2): 9452–9462. Published online 2021 Dec 27. doi: 10.1080/21655979.2021.1995100

PMCID:: PMC8809990

Abstract Article PDF–3.1M

Select item 55639973.

Upregulation of LYAR induces neuroblastoma cell proliferation and survival

Yuting Sun, Bernard Atmadibrata, Denise Yu, Matthew Wong, Bing Liu, Nicholas Ho, Dora Ling, Andrew E Tee, Jenny Wang, Imran N Mungrue, Pei Y Liu, Tao Liu

Cell Death Differ. 2017 Sep; 24(9): 1645–1654. Published online 2017 Jul 7. doi: 10.1038/cdd.2017.98

PMCID:: PMC5563997

Abstract Article PDF–3.9M

Select item 68032894.

LYAR Suppresses Beta Interferon Induction by Targeting Phosphorylated Interferon Regulatory Factor 3

Cha Yang, Xiaokun Liu, Tailang Cheng, Rong Xiao, Qingxia Gao, Fan Ming, Meilin Jin, Huanchun Chen, Hongbo Zhou

J Virol. 2019 Nov 1; 93(21): e00769-19. Prepublished online 2019 Aug 14. Published online 2019 Oct 15. doi: 10.1128/JVI.00769-19

PMCID:: PMC6803289

Abstract Article PDF–3.5M

Select item 47417375.

LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression

Yupeng Wu, Ming Liu, Zhuchen Li, Xiao-Bin Wu, Ying Wang, Yadong Wang, Min Nie, Feifei Huang, Junyi Ju, Chi Ma, Renxiang Tan, Ke Zen, Chen-Yu Zhang, Keqin Fu, Yu-Gen Chen, Ming-Rong Wang, Quan Zhao

Oncotarget. 2015 Oct 20; 6(32): 32890–32901. Published online 2015 Sep 25. doi: 10.18632/oncotarget.5335

PMCID:: PMC4741737

Abstract Article PDF–4.9M

Select item 68211716.

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA

Keiichi Izumikawa, Hideaki Ishikawa, Harunori Yoshikawa, Sally Fujiyama, Akira Watanabe, Hiroyuki Aburatani, Hiroyuki Tachikawa, Toshiya Hayano, Yutaka Miura, Toshiaki Isobe, Richard J Simpson, Li Li, Jinrong Min, Nobuhiro Takahashi

Nucleic Acids Res. 2019 Nov 4; 47(19): 10357–10372. Published online 2019 Sep 2. doi: 10.1093/nar/gkz747

PMCID:: PMC6821171

Abstract Article PDF–4.6M

Select item 41508097.

Human fetal globin gene expression is regulated by LYAR

Junyi Ju, Ying Wang, Ronghua Liu, Yichong Zhang, Zhen Xu, Yadong Wang, Yupeng Wu, Ming Liu, Loretta Cerruti, Fengwei Zou, Chi Ma, Ming Fang, Renxiang Tan, Stephen M. Jane, Quan Zhao

Nucleic Acids Res. 2014 Sep 2; 42(15): 9740–9752. Published online 2014 Aug 4. doi: 10.1093/nar/gku718

PMCID:: PMC4150809

Abstract Article PDF–1.0M

Select item 48732598.

Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway

Deqiang Han, Junbo Liang, Yalan Lu, Longchang Xu, Shiying Miao, Lin-Yu Lu, Wei Song, Linfang Wang

PLoS One. 2016; 11(5): e0155476. Published online 2016 May 19. doi: 10.1371/journal.pone.0155476

PMCID:: PMC4873259

Abstract Article PDF–6.8M

Select item 45718799.

Nucleolar GTP-binding Protein-1 (NGP-1) Promotes G₁ to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21^Cip1/Waf1

Debduti Datta, Kumaraswamy Anbarasu, Suryaraja Rajabather, Rangasamy Sneha Priya, Pavitra Desai, Sundarasamy Mahalingam

J Biol Chem. 2015 Aug 28; 290(35): 21536–21552. Published online 2015 Jul 9. doi: 10.1074/jbc.M115.637280

PMCID:: PMC4571879

Abstract Article PDF–3.6M

Select item 304613710.

Quantitative Proteomics Identifies the Myb-Binding Protein p160 as a Novel Target of the von Hippel-Lindau Tumor Suppressor

Yanlai Lai, Mei Qiao, Meihua Song, Susan T. Weintraub, Yuzuru Shiio

PLoS One. 2011; 6(2): e16975. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0016975

PMCID:: PMC3046137

Abstract Article PDF–685K

Select item 927418611.

Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis

Hong-Guang Zhang, Bin Wang, Yong Yang, Xuan Liu, Junjie Wang, Ning Xin, Shifeng Li, Ying Miao, Qiuyu Wu, Tingting Guo, Yukang Yuan, Yibo Zuo, Xiangjie Chen, Tengfei Ren, Chunsheng Dong, Jun Wang, Hang Ruan, Miao Sun, Xingshun Xu, Hui Zheng

Cell Res. 2022 Oct; 32(10): 897–913. Published online 2022 Jul 12. doi: 10.1038/s41422-022-00689-9

PMCID:: PMC9274186

Abstract Article PDF–6.7M

Select item 738783012.

An NAD⁺-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39

Ling Dong, Le Yu, Hui Li, Lei Shi, Zhong Luo, Huakan Zhao, Zhaojian Liu, Guobing Yin, Xiaohua Yan, Zhenghong Lin

iScience. 2020 Aug 21; 23(8): 101351. Published online 2020 Jul 9. doi: 10.1016/j.isci.2020.101351

PMCID:: PMC7387830

Abstract Article PDF–7.2M

Select item 740262113.

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

Matthias Thoms, Robert Buschauer, Michael Ameismeier, Lennart Koepke, Timo Denk, Maximilian Hirschenberger, Hanna Kratzat, Manuel Hayn, Timur Mackens-Kiani, Jingdong Cheng, Jan H. Straub, Christina M. Stürzel, Thomas Fröhlich, Otto Berninghausen, Thomas Becker, Frank Kirchhoff, Konstantin M. J. Sparrer, Roland Beckmann

Science. 2020 Sep 4; 369(6508): 1249–1255. Published online 2020 Jul 17. doi: 10.1126/science.abc8665

PMCID:: PMC7402621

Abstract Article PDF–2.0M

Select item 884467914.

Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy

Lei Liu, Fang Bai, Hui Song, Rong Xiao, Yuzhen Wang, Huimin Yang, Xiaolei Ren, Shuangjie Li, Lifen Gao, Chunhong Ma, Xiangdong Yang, Xiaohong Liang

Redox Biol. 2022 Apr; 50: 102260. Published online 2022 Feb 7. doi: 10.1016/j.redox.2022.102260

Correction in:: Redox Biol. 2022 Jun; 52: 102302.

PMCID:: PMC8844679

Abstract Article PDF–23M

Select item 485571815.

Identification of the BRD1 interaction network and its impact on mental disorder risk

Tue Fryland, Jane H. Christensen, Jonatan Pallesen, Manuel Mattheisen, Johan Palmfeldt, Mads Bak, Jakob Grove, Ditte Demontis, Jenny Blechingberg, Hong Sain Ooi, Mette Nyegaard, Mads E. Hauberg, Niels Tommerup, Niels Gregersen, Ole Mors, Thomas J. Corydon, Anders L. Nielsen, Anders D. Børglum

Genome Med. 2016; 8: 53. Published online 2016 May 3. doi: 10.1186/s13073-016-0308-x

PMCID:: PMC4855718

Abstract Article PDF–2.8M

Select item 719738916.

A Genome-wide ER-Phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation

Jin Rui Liang, Emily Lingeman, Thao Luong, Saba Ahmed, Matthias Muhar, Truc Nguyen, James Olzmann, Jacob E. Corn

Cell. Author manuscript; available in PMC 2021 Mar 19.

Published in final edited form as: Cell. 2020 Mar 19; 180(6): 1160–1177.e20. Published online 2020 Mar 10. doi: 10.1016/j.cell.2020.02.017

PMCID:: PMC7197389

Abstract Article PDF–3.2M

Select item 837237717.

circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1

Shuying Shen, Yute Yang, Panyang Shen, Jun Ma, Bin Fang, Qingxin Wang, Kefan Wang, Peihua Shi, Shunwu Fan, Xiangqian Fang

Ann Rheum Dis. 2021 Sep; 80(9): 1209–1219. Published online 2021 May 26. doi: 10.1136/annrheumdis-2021-219969

PMCID:: PMC8372377

Abstract Article PDF–7.8M

Select item 731613118.

EIF3H orchestrates Hippo pathway-mediated oncogenesis via catalytic control of YAP stability

Zhuan Zhou, Honghong Zhou, Luca Ponzoni, Aiping Luo, Rui Zhu, Mingjing He, Yi Huang, Kun-Liang Guan, Ivet Bahar, Zhihua Liu, Yong Wan

Cancer Res. Author manuscript; available in PMC 2020 Dec 15.

Published in final edited form as: Cancer Res. 2020 Jun 15; 80(12): 2550–2563. Published online 2020 Apr 8. doi: 10.1158/0008-5472.CAN-19-3718

PMCID:: PMC7316131

Abstract Article PDF–1.7M

Select item 910776519.

RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma

Cheng Lin, Meifang Li, Na Lin, Jingfeng Zong, Jianji Pan, Yunbin Ye

BMC Cancer. 2022; 22: 549. Published online 2022 May 15. doi: 10.1186/s12885-022-09641-x

PMCID:: PMC9107765

Abstract Article PDF–7.0M

Select item 534359320.

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor

Yuri Kotani, Daisuke Morito, Kenshiro Sakata, Shiori Ainuki, Munechika Sugihara, Tomohisa Hatta, Shun-ichiro Iemura, Seiji Takashima, Tohru Natsume, Kazuhiro Nagata

Sci Rep. 2017; 7: 44293. Published online 2017 Mar 9. doi: 10.1038/srep44293