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Select item 87288711.

PRKACB variants in skeletal disease or adrenocortical hyperplasia: effects on protein kinase A

Stephanie Espiard, Ludivine Drougat, Nikolaos Settas, Sara Haydar, Kerstin Bathon, Edra London, Isaac Levy, Fabio R. Faucz, Davide Calebiro, Jérôme Bertherat, Dong Li, Michael A. Levine, Constantine A. Stratakis

Endocr Relat Cancer. Author manuscript; available in PMC 2022 Jan 5.

Published in final edited form as: Endocr Relat Cancer. 2020 Nov; 27(11): 647–656. doi: 10.1530/ERC-20-0309

PMCID:: PMC8728871

Abstract Article PDF–799K

Select item 85265962.

Novel implications of a strictly monomorphic (GCC) repeat in the human PRKACB gene

Safoura Khamse, Zahra Jafarian, Ali Bozorgmehr, Mostafa Tavakoli, Hossein Afshar, Maryam Keshavarz, Razieh Moayedi, Mina Ohadi

Sci Rep. 2021; 11: 20629. Published online 2021 Oct 19. doi: 10.1038/s41598-021-99932-3

PMCID:: PMC8526596

Abstract Article PDF–1.5M

Select item 38432803.

Association between PKA gene polymorphism and NTDs in high risk Chinese population in Shanxi

Jian Wu, Xiaolin Lu, Zhen Wang, Shaofang Shangguan, Shaoyan Chang, Rui Li, Lihua Wu, Yihua Bao, Bo Niu, Li Wang, Ting Zhang

Int J Clin Exp Pathol. 2013; 6(12): 2968–2974. Published online 2013 Nov 15.

PMCID:: PMC3843280

Abstract Article PDF–254K

Select item 89193204.

Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC

Yuling Huang, Liu Feng, Yongqiang Bao, Yun Zhang, Jinghui Liang, Qingfeng Mao, Jingao Li, Chunling Jiang

Exp Biol Med (Maywood) 2022 Mar; 247(5): 426–432. Published online 2021 Nov 17. doi: 10.1177/15353702211059829

PMCID:: PMC8919320

Abstract Article PDF–1.4M

Select item 70105545.

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct

Aatur D. Singhi, Laura D. Wood, Emma Parks, Michael S. Torbenson, Matthäus Felsenstein, Ralph H. Hruban, Marina N. Nikiforova, Abigail I. Wald, Cihan Kaya, Yuri E. Nikiforov, Laura Favazza, Jin He, Kevin McGrath, Kenneth E. Fasanella, Randall E. Brand, Anne Marie Lennon, Alessandro Furlan, Anil K. Dasyam, Amer H. Zureikat, Herbert J. Zeh, Kenneth Lee, David L. Bartlett, Adam Slivka

Gastroenterology. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Gastroenterology. 2020 Feb; 158(3): 573–582.e2. Published online 2019 Oct 31. doi: 10.1053/j.gastro.2019.10.028

PMCID:: PMC7010554

Abstract Article PDF–1.2M

Select item 69731916.

MicroRNA-384 Inhibits the Progression of Papillary Thyroid Cancer by Targeting PRKACB

Yongxia Wang, Beixi Wang, Hong Zhou, Xiangnan Zhang, Xinlai Qian, Jing Cui

Biomed Res Int. 2020; 2020: 4983420. Published online 2020 Jan 8. doi: 10.1155/2020/4983420

PMCID:: PMC6973191

Abstract Article PDF–1.4M

Select item 28235247.

Global Consequences of Activation Loop Phosphorylation on Protein Kinase A

Jon M. Steichen, Ganesh H. Iyer, Sheng Li, S. Adrian Saldanha, Michael S. Deal, Virgil L. Woods, Jr., Susan S. Taylor

J Biol Chem. 2010 Feb 5; 285(6): 3825–3832. Published online 2009 Dec 4. doi: 10.1074/jbc.M109.061820

PMCID:: PMC2823524

Abstract Article PDF–1.7M

Select item 1544698.

PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts

Haruhisa Higuchi, Toshihide Yamashita, Hideki Yoshikawa, Masaya Tohyama

EMBO J. 2003 Apr 15; 22(8): 1790–1800. doi: 10.1093/emboj/cdg177

PMCID:: PMC154469

Abstract Article PDF–359K

Select item 43942579.

Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi

Seiko Susuki-Miyata, Masanori Miyata, Byung-Cheol Lee, Haidong Xu, Hirofumi Kai, Chen Yan, Jian-Dong Li

Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1800–E1809. Published online 2015 Mar 23. doi: 10.1073/pnas.1418716112

PMCID:: PMC4394257

Abstract Article PDF–1.6M

Select item 270895510.

The Paradoxical Increase in Cortisol Secretion Induced by Dexamethasone in Primary Pigmented Nodular Adrenocortical Disease Involves a Glucocorticoid Receptor-Mediated Effect of Dexamethasone on Protein Kinase A Catalytic Subunits

Estelle Louiset, Constantine A. Stratakis, Véronique Perraudin, Kurt J. Griffin, Rossella Libé, Sylvie Cabrol, Bruno Fève, Jacques Young, Lionel Groussin, Jérôme Bertherat, Hervé Lefebvre

J Clin Endocrinol Metab. 2009 Jul; 94(7): 2406–2413. Published online 2009 Apr 21. doi: 10.1210/jc.2009-0031

PMCID:: PMC2708955

Abstract Article

Select item 155751411.

Identification, cloning and characterization of a novel 47 kDa murine PKA C subunit homologous to human and bovine Cβ2

Ane Funderud, Heidi H Henanger, Tilahun T Hafte, Paul S Amieux, Sigurd Ørstavik, Bjørn S Skålhegg

BMC Biochem. 2006; 7: 20. Published online 2006 Aug 4. doi: 10.1186/1471-2091-7-20

PMCID:: PMC1557514

Abstract Article PDF–392K

Select item 767500212.

Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome

Adrian Palencia-Campos, Phillip C. Aoto, Erik M.F. Machal, Ana Rivera-Barahona, Patricia Soto-Bielicka, Daniela Bertinetti, Blaine Baker, Lily Vu, Francesca Piceci-Sparascio, Isabella Torrente, Eveline Boudin, Silke Peeters, Wim Van Hul, Celine Huber, Dominique Bonneau, Michael S. Hildebrand, Matthew Coleman, Melanie Bahlo, Mark F. Bennett, Amy L. Schneider, Ingrid E. Scheffer, Maria Kibæk, Britta S. Kristiansen, Mahmoud Y. Issa, Mennat I. Mehrez, Samira Ismail, Jair Tenorio, Gaoyang Li, Bjørn Steen Skålhegg, Ghada A. Otaify, Samia Temtamy, Mona Aglan, Aia E. Jønch, Alessandro De Luca, Geert Mortier, Valérie Cormier-Daire, Alban Ziegler, Mathew Wallis, Pablo Lapunzina, Friedrich W. Herberg, Susan S. Taylor, Victor L. Ruiz-Perez

Am J Hum Genet. 2020 Nov 5; 107(5): 977–988. Published online 2020 Oct 14. doi: 10.1016/j.ajhg.2020.09.005

PMCID:: PMC7675002

Abstract Article PDF–3.0M

Select item 652921813.

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

Jenna L Jewell, Vivian Fu, Audrey W Hong, Fa-Xing Yu, Delong Meng, Chase H Melick, Huanyu Wang, Wai-Ling Macrina Lam, Hai-Xin Yuan, Susan S Taylor, Kun-Liang Guan

eLife. 2019; 8: e43038. Published online 2019 May 21. doi: 10.7554/eLife.43038

PMCID:: PMC6529218

Abstract Article PDF–3.0M

Select item 372290414.

Genome-wide association study identifies a novel variant in RAD51B associated with male breast cancer risk

Nick Orr, Alina Lemnrau, Rosie Cooke, Olivia Fletcher, Katarzyna Tomczyk, Michael Jones, Nichola Johnson, Christopher J Lord, Costas Mitsopoulos, Marketa Zvelebil, Simon S McDade, Gemma Buck, Christine Blancher, KConFab Consortium, Alison H Trainer, Paul A James, Stig E Bojesen, Susanne Bokmand, Heli Nevanlinna, Johanna Mattson, Eitan Friedman, Yael Laitman, Domenico Palli, Giovanna Masala, Ines Zanna, Laura Ottini, Giuseppe Giannini, Antoinette Hollestelle, Ans M.W. van den Ouweland, Srdjan Novakovic, Mateja Krajc, Manuela Gago-Dominguez, Jose Esteban Castelao, Håkan Olsson, Ingrid Hedenfalk, Douglas F Easton, Paul DP Pharoah, Alison M Dunning, D Timothy Bishop, Susan L Neuhausen, Linda Steele, Richard S Houlston, Montserrat Garcia-Closas, Alan Ashworth, Anthony J Swerdlow

Nat Genet. Author manuscript; available in PMC 2013 Jul 25.

Published in final edited form as: Nat Genet. 2012 Nov; 44(11): 1182–1184. Published online 2012 Sep 23. doi: 10.1038/ng.2417

PMCID:: PMC3722904

Abstract Article PDF–257K

Select item 317974615.

G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A

Anne Kristin Aksaas, Anja CV Larsen, Marie Rogne, Ken Rosendal, Anne-Katrine Kvissel, Bjørn Steen Skålhegg

J Mol Signal. 2011; 6: 10. Published online 2011 Aug 31. doi: 10.1186/1750-2187-6-10

PMCID:: PMC3179746

Abstract Article PDF–14M

Select item 562649816.

PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation

Bing-Ru Yan, Lu Zhou, Ming-Ming Hu, Mi Li, Heng Lin, Yan Yang, Yan-Yi Wang, Hong-Bing Shu

PLoS Pathog. 2017 Sep; 13(9): e1006648. Published online 2017 Sep 21. doi: 10.1371/journal.ppat.1006648

PMCID:: PMC5626498

Abstract Article PDF–2.3M

Select item 383229717.

Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls

Richard C. Shelton, D. Hal Manier, David A. Lewis

Int J Neuropsychopharmacol. Author manuscript; available in PMC 2013 Nov 18.

Published in final edited form as: Int J Neuropsychopharmacol. 2009 Oct; 12(9): 10.1017/S1461145709000285. Published online 2009 Jul 2. doi: 10.1017/S1461145709000285

PMCID:: PMC3832297

Abstract Article PDF–296K

Select item 283807718.

Cross Talk between Phosphatidylinositol 3-Kinase and Cyclic AMP (cAMP)-Protein Kinase A Signaling Pathways at the Level of a Protein Kinase B/β-Arrestin/cAMP Phosphodiesterase 4 Complex

Elisa Bjørgo, Silje A. Solheim, Hilde Abrahamsen, George S. Baillie, Kim M. Brown, Torunn Berge, Klaus Okkenhaug, Miles D. Houslay, Kjetil Taskén

Mol Cell Biol. 2010 Apr; 30(7): 1660–1672. Published online 2010 Jan 19. doi: 10.1128/MCB.00696-09

Correction in:: Mol Cell Biol. 2022 Feb; 42(2): e00556-21.

PMCID:: PMC2838077

Abstract Article PDF–2.9M

Select item 352710219.

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction

Slava Rom, Marco Pacifici, Giovanni Passiatore, Susanna Aprea, Agnieszka Waligorska, Luis Del Valle, Francesca Peruzzi

Biochim Biophys Acta. Author manuscript; available in PMC 2012 Dec 20.

Published in final edited form as: Biochim Biophys Acta. 2011 Oct; 1813(10): 1836–1844. Published online 2011 Jul 1. doi: 10.1016/j.bbamcr.2011.06.012

PMCID:: PMC3527102

Abstract Article PDF–1.7M

Select item 667107220.

Protein Kinase A-Induced Phosphorylation of the p65 Subunit of Nuclear Factor-κB Promotes Schwann Cell Differentiation into a Myelinating Phenotype

Choya Yoon, Zeljka Korade, Bruce D. Carter

J Neurosci. 2008 Apr 2; 28(14): 3738–3746. doi: 10.1523/JNEUROSCI.4439-07.2008

PMCID:: PMC6671072

Abstract Article PDF–386K

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