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Select item 89439161.

A ubiquitous disordered protein interaction module orchestrates transcription elongation

Katerina Cermakova, Jonas Demeulemeester, Vanda Lux, Monika Nedomova, Seth R. Goldman, Eric A. Smith, Pavel Srb, Rozalie Hexnerova, Milan Fabry, Marcela Madlikova, Magdalena Horejsi, Jan De Rijck, Zeger Debyser, Karen Adelman, H. Courtney Hodges, Vaclav Veverka

Science. Author manuscript; available in PMC 2022 Nov 26.

Published in final edited form as: Science. 2021 Nov 26; 374(6571): 1113–1121. Published online 2021 Nov 25. doi: 10.1126/science.abe2913

PMCID:: PMC8943916

Abstract Article PDF–3.1M

Select item 14503332.

A sequence motif conserved in diverse nuclear proteins identifies a protein interaction domain utilised for nuclear targeting by human TFIIS

Yan Ling, Abigail J. Smith, Garry T. Morgan

Nucleic Acids Res. 2006; 34(8): 2219–2229. Published online 2006 Apr 28. doi: 10.1093/nar/gkl239

PMCID:: PMC1450333

Abstract Article PDF–556K

Select item 60650153.

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Subhalakshmi Sharma, Kateřina Čermáková, Jan De Rijck, Jonas Demeulemeester, Milan Fábry, Sara El Ashkar, Siska Van Belle, Martin Lepšík, Petr Tesina, Vojtěch Duchoslav, Petr Novák, Martin Hubálek, Pavel Srb, Frauke Christ, Pavlína Řezáčová, H. Courtney Hodges, Zeger Debyser, Václav Veverka

Proc Natl Acad Sci U S A. 2018 Jul 24; 115(30): E7053–E7062. Published online 2018 Jul 11. doi: 10.1073/pnas.1803909115

PMCID:: PMC6065015

Abstract Article PDF–1.8M

Select item 26070754.

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

Sunnie M. Yoh, Joseph S. Lucas, Katherine A. Jones

Genes Dev. 2008 Dec 15; 22(24): 3422–3434. doi: 10.1101/gad.1720008

PMCID:: PMC2607075

Abstract Article PDF–677K

Select item 17708995.

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

Sunnie M. Yoh, Helen Cho, Loni Pickle, Ronald M. Evans, Katherine A. Jones

Genes Dev. 2007 Jan 15; 21(2): 160–174. doi: 10.1101/gad.1503107

PMCID:: PMC1770899

Abstract Article PDF–804K

Select item 39475846.

Phosphoproteomics screen reveals Akt isoform-specific signals linking RNA processing to lung cancer

Ioannis Sanidas, Christos Polytarchou, Maria Hatziapostolou, Scott A. Ezell, Filippos Kottakis, Lan Hu, Ailan Guo, Jianxin Xie, Michael J. Comb, Dimitrios Iliopoulos, Philip N. Tsichlis

Mol Cell. Author manuscript; available in PMC 2015 Feb 20.

Published in final edited form as: Mol Cell. 2014 Feb 20; 53(4): 577–590. Published online 2014 Jan 23. doi: 10.1016/j.molcel.2013.12.018

PMCID:: PMC3947584

Abstract Article PDF–5.0M

Select item 41833137.

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

Cornelius A. Rietveld, Tõnu Esko, Gail Davies, Tune H. Pers, Patrick Turley, Beben Benyamin, Christopher F. Chabris, Valur Emilsson, Andrew D. Johnson, James J. Lee, Christiaan de Leeuw, Riccardo E. Marioni, Sarah E. Medland, Michael B. Miller, Olga Rostapshova, Sven J. van der Lee, Anna A. E. Vinkhuyzen, Najaf Amin, Dalton Conley, Jaime Derringer, Cornelia M. van Duijn, Rudolf Fehrmann, Lude Franke, Edward L. Glaeser, Narelle K. Hansell, Caroline Hayward, William G. Iacono, Carla Ibrahim-Verbaas, Vincent Jaddoe, Juha Karjalainen, David Laibson, Paul Lichtenstein, David C. Liewald, Patrik K. E. Magnusson, Nicholas G. Martin, Matt McGue, George McMahon, Nancy L. Pedersen, Steven Pinker, David J. Porteous, Danielle Posthuma, Fernando Rivadeneira, Blair H. Smith, John M. Starr, Henning Tiemeier, Nicholas J. Timpson, Maciej Trzaskowski, André G. Uitterlinden, Frank C. Verhulst, Mary E. Ward, Margaret J. Wright, George Davey Smith, Ian J. Deary, Magnus Johannesson, Robert Plomin, Peter M. Visscher, Daniel J. Benjamin, David Cesarini, Philipp D. Koellinger

Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38): 13790–13794. Published online 2014 Sep 8. doi: 10.1073/pnas.1404623111

Correction in:: Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4): E380.

PMCID:: PMC4183313

Abstract Article PDF–650K

Select item 71455208.

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation

Frauke Liebelt, Joost Schimmel, Matty Verlaan – de Vries, Esra Klemann, Martin E van Royen, Yana van der Weegen, Martijn S Luijsterburg, Leon H Mullenders, Alex Pines, Wim Vermeulen, Alfred C O Vertegaal

Nucleic Acids Res. 2020 Jan 10; 48(1): 231–248. Published online 2019 Nov 13. doi: 10.1093/nar/gkz977

PMCID:: PMC7145520

Abstract Article PDF–7.6M

Select item 59223779.

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer

Aida Barreiro-Alonso, Mónica Lamas-Maceiras, Rosa García-Díaz, Esther Rodríguez-Belmonte, Lu Yu, Mercedes Pardo, Jyoti S. Choudhary, María Esperanza Cerdán

Oncotarget. 2018 Apr 10; 9(27): 19050–19064. Published online 2018 Apr 10. doi: 10.18632/oncotarget.24887

PMCID:: PMC5922377

Abstract Article PDF–1.7M

Select item 145936510.

Phosphoproteome analysis of the human mitotic spindle

Marjaana Nousiainen, Herman H. W. Silljé, Guido Sauer, Erich A. Nigg, Roman Körner

Proc Natl Acad Sci U S A. 2006 Apr 4; 103(14): 5391–5396. Published online 2006 Mar 24. doi: 10.1073/pnas.0507066103

PMCID:: PMC1459365

Abstract Article PDF–370K

Select item 729517911.

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome

Gerald Dayebgadoh, Mihaela E. Sardiu, Laurence Florens, Michael P. Washburn

J Proteome Res. Author manuscript; available in PMC 2020 Jun 15.

Published in final edited form as: J Proteome Res. 2019 Sep 6; 18(9): 3479–3491. Published online 2019 Aug 9. doi: 10.1021/acs.jproteome.9b00373

PMCID:: PMC7295179

Abstract Article PDF–2.6M

Select item 660120812.

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

Manal Alsulami, Nayla Munawar, Eugene Dillon, Giorgio Oliviero, Kieran Wynne, Mona Alsolami, Catherine Moss, Peadar Ó Gaora, Fergal O'Meara, David Cotter, Gerard Cagney

Mol Cell Proteomics. 2019 Jul; 18(7): 1428–1436. Published online 2019 May 10. doi: 10.1074/mcp.RA119.001518

PMCID:: PMC6601208

Abstract Article PDF–1.8M

Select item 546003513.

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

Philippe Cloutier, Christian Poitras, Mathieu Durand, Omid Hekmat, Émilie Fiola-Masson, Annie Bouchard, Denis Faubert, Benoit Chabot, Benoit Coulombe

Nat Commun. 2017; 8: 15615. Published online 2017 May 31. doi: 10.1038/ncomms15615

PMCID:: PMC5460035

Abstract Article PDF–2.9M

Select item 962912114.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 509804215.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

Select item 573755516.

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality

Helen Hoffmeister, Andreas Fuchs, Fabian Erdel, Sophia Pinz, Regina Gröbner-Ferreira, Astrid Bruckmann, Rainer Deutzmann, Uwe Schwartz, Rodrigo Maldonado, Claudia Huber, Anne-Sarah Dendorfer, Karsten Rippe, Gernot Längst

Nucleic Acids Res. 2017 Oct 13; 45(18): 10534–10554. Published online 2017 Aug 28. doi: 10.1093/nar/gkx711

PMCID:: PMC5737555

Abstract Article PDF–7.2M

Select item 954034517.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 438371318.

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Jean-Philippe Lambert, Monika Tucholska, Christopher Go, James D.R. Knight, Anne-Claude Gingras

J Proteomics. Author manuscript; available in PMC 2016 Apr 6.

Published in final edited form as: J Proteomics. 2015 Apr 6; 118: 81–94. Published online 2014 Oct 2. doi: 10.1016/j.jprot.2014.09.011

PMCID:: PMC4383713

Abstract Article PDF–1.4M

Select item 797970519.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

Select item 752655120.

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna

JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117

PMCID:: PMC7526551

Abstract Article PDF–9.1M

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