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Items: 1 to 20 of 46

1.
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex
Lauren G. Mascibroda, Mohammad Shboul, Nathan D. Elrod, Laurence Colleaux, Hanan Hamamy, Kai-Lieh Huang, Natoya Peart, Moirangthem Kiran Singh, Hane Lee, Barry Merriman, Jeanne N. Jodoin, Poojitha Sitaram, Laura A. Lee, Raja Fathalla, Baeth Al-Rawashdeh, Osama Ababneh, Mohammad El-Khateeb, Nathalie Escande-Beillard, Stanley F. Nelson, Yixuan Wu, Liang Tong, Linda J. Kenney, Sudipto Roy, William K. Russell, Jeanne Amiel, Bruno Reversade, Eric J. Wagner
Nat Commun. 2022; 13: 6054. Published online 2022 Oct 13. doi: 10.1038/s41467-022-33547-8
PMCID:
PMC9559116
AbstractArticlePDF–4.0M
2.
Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry
Jeanne N. Jodoin, Mohammad Shboul, Poojitha Sitaram, Hala Zein-Sabatto, Bruno Reversade, Ethan Lee, Laura A. Lee
Mol Biol Cell. 2012 Dec 15; 23(24): 4713–4724. doi: 10.1091/mbc.E12-07-0558
PMCID:
PMC3521680
AbstractArticlePDF–2.5M
3.
Structure of the catalytic core of the Integrator complex
Moritz M. Pfleiderer, Wojciech P. Galej
Mol Cell. 2021 Mar 18; 81(6): 1246–1259.e8. doi: 10.1016/j.molcel.2021.01.005
PMCID:
PMC7980224
AbstractArticle
4.
The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts
Felipe Beckedorff, Ezra Blumenthal, Lucas Ferreira daSilva, Yuki Aoi, Pradeep Reddy Cingaram, Jingyin Yue, Anda Zhang, Sadat Dokaneheifard, Monica Guiselle Valencia, Gabriel Gaidosh, Ali Shilatifard, Ramin Shiekhattar
Cell Rep. Author manuscript; available in PMC 2020 Aug 14.
Published in final edited form as: Cell Rep. 2020 Jul 21; 32(3): 107917. doi: 10.1016/j.celrep.2020.107917
PMCID:
PMC7427568
AbstractArticlePDF–2.8M
5.
INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
Kevin Sabath, Melanie L. Stäubli, Sabrina Marti, Alexander Leitner, Murielle Moes, Stefanie Jonas
Nat Commun. 2020; 11: 3422. Published online 2020 Jul 9. doi: 10.1038/s41467-020-17232-2
PMCID:
PMC7347597
AbstractArticlePDF–2.5M
6.
asunder Is a Critical Regulator of Dynein–Dynactin Localization during Drosophila Spermatogenesis
Michael A. Anderson, Jeanne N. Jodoin, Ethan Lee, Karen G. Hales, Thomas S. Hays, Laura A. Lee
Mol Biol Cell. 2009 Jun 1; 20(11): 2709–2721. doi: 10.1091/mbc.E08-12-1165
PMCID:
PMC2688550
AbstractArticlePDF–845K
7.
Immunomic analysis of human sarcoma
Sang-Yull Lee, Yuichi Obata, Masahiro Yoshida, Elisabeth Stockert, Barbara Williamson, Achim A. Jungbluth, Yao-Tseng Chen, Lloyd J. Old, Matthew J. Scanlan
Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5): 2651–2656. Published online 2003 Feb 24. doi: 10.1073/pnas.0437972100
PMCID:
PMC151395
AbstractArticlePDF–117K
8.
Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the Integrator complex
Jeanne N. Jodoin, Poojitha Sitaram, Todd R. Albrecht, Sarah B. May, Mohammad Shboul, Ethan Lee, Bruno Reversade, Eric J. Wagner, Laura A. Lee
Mol Biol Cell. 2013 Sep 15; 24(18): 2954–2965. doi: 10.1091/mbc.E13-05-0254
PMCID:
PMC3771956
AbstractArticlePDF–2.0M
9.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin, Elisa Barbieri, Deborah A. Knight, Sarah Offley, Stefan Bjelosevic, Matteo Costacurta, Izabela Todorovski, Conor J. Kearney, Jarrod J. Sandow, Zheng Fan, Benjamin Blyth, Victoria McLeod, Joseph H.A. Vissers, Karolina Pavic, Ben P. Martin, Gareth Gregory, Elena Demosthenous, Magnus Zethoven, Isabella Y. Kong, Edwin D. Hawkins, Simon J. Hogg, Madison J. Kelly, Andrea Newbold, Kaylene J. Simpson, Otto Kauko, Kieran F. Harvey, Michael Ohlmeyer, Jukka Westermarck, Nathanael Gray, Alessandro Gardini, Ricky W. Johnstone
Cell. Author manuscript; available in PMC 2022 Jun 10.
Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3143–3162.e32. Published online 2021 May 17. doi: 10.1016/j.cell.2021.04.022
PMCID:
PMC8567840
AbstractArticlePDF–2.8M
10.
Streamlined analysis schema for high-throughput identification of endogenous protein complexes
Anna Malovannaya, Yehua Li, Yaroslava Bulynko, Sung Yun Jung, Yi Wang, Rainer B. Lanz, Bert W. O’Malley, Jun Qin
Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2431–2436. Published online 2010 Jan 22. doi: 10.1073/pnas.0912599106
Correction in:
Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13): 6118.
PMCID:
PMC2823922
AbstractArticlePDF–566K
11.
CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1
Hong Luo, Zhicheng Zhou, Shan Huang, Mengru Ma, Manyu Zhao, Lixu Tang, Yuan Quan, Yiming Zeng, Li Su, Jongchan Kim, Peijing Zhang
Cell Death Dis. 2021 Sep; 12(9): 820. Published online 2021 Aug 30. doi: 10.1038/s41419-021-04114-8
PMCID:
PMC8405615
AbstractArticlePDF–3.5M
12.
A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks
Etsuko Miyamoto-Sato, Shigeo Fujimori, Masamichi Ishizaka, Naoya Hirai, Kazuyo Masuoka, Rintaro Saito, Yosuke Ozawa, Katsuya Hino, Takanori Washio, Masaru Tomita, Tatsuhiro Yamashita, Tomohiro Oshikubo, Hidetoshi Akasaka, Jun Sugiyama, Yasuo Matsumoto, Hiroshi Yanagawa
PLoS One. 2010; 5(2): e9289. Published online 2010 Feb 24. doi: 10.1371/journal.pone.0009289
PMCID:
PMC2827538
AbstractArticlePDF–676K
13.
MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang
Cell Rep. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860
PMCID:
PMC7382313
AbstractArticlePDF–2.6M
14.
Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner
Lauriane Vélot, Frédéric Lessard, Félix-Antoine Bérubé-Simard, Christophe Tav, Bertrand Neveu, Valentine Teyssier, Imène Boudaoud, Ugo Dionne, Noémie Lavoie, Steve Bilodeau, Frédéric Pouliot, Nicolas Bisson
Mol Cell Proteomics. 2021; 20: 100064. Published online 2021 Feb 26. doi: 10.1016/j.mcpro.2021.100064
PMCID:
PMC8050775
AbstractArticlePDF–3.6M
15.
Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease
Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Cell. Author manuscript; available in PMC 2023 Mar 3.
Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021
PMCID:
PMC8923057
AbstractArticlePDF–2.5M
16.
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold
Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo
Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134
PMCID:
PMC9475462
AbstractArticlePDF–4.6M
17.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
18.
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras
Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006
PMCID:
PMC6375729
AbstractArticlePDF–10M
19.
A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing
Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl
Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2
PMCID:
PMC8894380
AbstractArticlePDF–5.6M
20.
Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice
David Llères, Marco Denegri, Marco Biggiogera, Paul Ajuh, Angus I Lamond
EMBO Rep. 2010 Jun; 11(6): 445–451. Published online 2010 May 14. doi: 10.1038/embor.2010.64
PMCID:
PMC2892320
AbstractArticlePDF–895K

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