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Select item 109217841.

Mammalian enabled protein enhances tamoxifen sensitivity of the hormone receptor-positive breast cancer patients by suppressing the AKT signaling pathway

Lifang He, Chuanghong She, Sen Jiang, Zhaochang Qi, Zihao Deng, Likeng Ji, Yukun Cui, Jundong Wu

Biol Direct. 2024; 19: 21. Published online 2024 Mar 8. doi: 10.1186/s13062-024-00464-3

PMCID:: PMC10921784

Abstract Article PDF–8.4M

Select item 61939442.

hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis

Francesca Di Modugno, Sheila Spada, Belinda Palermo, Paolo Visca, Pierluigi Iapicca, Anna Di Carlo, Barbara Antoniani, Isabella Sperduti, Anna Di Benedetto, Irene Terrenato, Marcella Mottolese, Francesco Gandolfi, Francesco Facciolo, Emily I. Chen, Martin A. Schwartz, Angela Santoni, Mina J. Bissell, Paola Nisticò

Oncogene. 2018; 37(42): 5605–5617. Published online 2018 Jun 15. doi: 10.1038/s41388-018-0364-3

PMCID:: PMC6193944

Abstract Article PDF–3.2M

Select item 61552923.

Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer

Di Chen, Li Xu, Xiaowei Li, Yi Chu, Mingzuo Jiang, Bing Xu, Min Zhao, Weijie Wang, Hua Wang, Huijie Kang, Kai Wang, Kaichun Wu, Jie Liang, Gui Ren

Cell Death Dis. 2018 Oct; 9(10): 998. Published online 2018 Sep 24. doi: 10.1038/s41419-018-1031-x

Correction in:: Cell Death Dis. 2019 May; 10(5): 366.

PMCID:: PMC6155292

Abstract Article PDF–6.1M

Select item 50662284.

The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior

Michele Balsamo, Chandrani Mondal, Guillaume Carmona, Leslie M. McClain, Daisy N. Riquelme, Jenny Tadros, Duan Ma, Eliza Vasile, John S. Condeelis, Douglas A. Lauffenburger, Frank B. Gertler

Sci Rep. 2016; 6: 35298. Published online 2016 Oct 17. doi: 10.1038/srep35298

PMCID:: PMC5066228

Abstract Article PDF–3.9M

Select item 44821905.

Mena^calc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer

Catherine L. Forse, Seema Agarwal, Dushanthi Pinnaduwage, Frank Gertler, John S. Condeelis, Juan Lin, Xiaonan Xue, Kimberly Johung, Anna Marie Mulligan, Thomas E. Rohan, Shelley B. Bull, Irene L. Andrulis

BMC Cancer. 2015; 15: 483. Published online 2015 Jun 27. doi: 10.1186/s12885-015-1468-6

PMCID:: PMC4482190

Abstract Article PDF–688K

Select item 42669316.

Invasive breast carcinoma cells from patients exhibit Mena^INV- and macrophage-dependent transendothelial migration

Jeanine Pignatelli, Sumanta Goswami, Joan G. Jones, Thomas E. Rohan, Evan Pieri, Xiaoming Chen, Esther Adler, Dianne Cox, Sara Maleki, Anne Bresnick, Frank B. Gertler, John S. Condeelis, Maja H. Oktay

Sci Signal. Author manuscript; available in PMC 2014 Dec 16.

Published in final edited form as: Sci Signal. 2014; 7(353): ra112. Published online 2014 Nov 25. doi: 10.1126/scisignal.2005329

PMCID:: PMC4266931

Abstract Article PDF–2.0M

Select item 39620297.

Quantitative assessment of invasive mena isoforms (Mena^calc) as an independent prognostic marker in breast cancer

Seema Agarwal, Frank B Gertler, Michele Balsamo, John S Condeelis, Robert L Camp, Xiaonan Xue, Juan Lin, Thomas E Rohan, David L Rimm

Breast Cancer Res. 2012; 14(5): R124. Published online 2012 Sep 12. doi: 10.1186/bcr3318

PMCID:: PMC3962029

Abstract Article PDF–2.4M

Select item 37285098.

The Possible Role of Mena Protein and Its Splicing-Derived Variants in Embryogenesis, Carcinogenesis, and Tumor Invasion: A Systematic Review of the Literature

Simona Gurzu, Diana Ciortea, Istvan Ember, Ioan Jung

Biomed Res Int. 2013; 2013: 365192. Published online 2013 Jul 14. doi: 10.1155/2013/365192

PMCID:: PMC3728509

Abstract Article PDF–511K

Select item 35111259.

Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors

Francesca Di Modugno, Pierluigi Iapicca, Aaron Boudreau, Marcella Mottolese, Irene Terrenato, Letizia Perracchio, Russ P. Carstens, Angela Santoni, Mina J. Bissell, Paola Nisticò

Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47): 19280–19285. Published online 2012 Nov 5. doi: 10.1073/pnas.1214394109

PMCID:: PMC3511125

Abstract Article PDF–1.1M

Select item 335213710.

Mena, a new available marker in tumors of salivary glands?

S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung

Eur J Histochem. 2012 Jan 20; 56(1): e8. Published online 2012 Feb 7. doi: 10.4081/ejh.2012.e8

PMCID:: PMC3352137

Abstract Article PDF–777K

Select item 304285711.

Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo

Sumanta Goswami, Ulrike Philippar, Daqian Sun, Antonia Patsialou, Jacob Avraham, Weigang Wang, Francesca Di Modugno, Paola Nistico, Frank B. Gertler, John S. Condeelis

Clin Exp Metastasis. Author manuscript; available in PMC 2011 Feb 22.

Published in final edited form as: Clin Exp Metastasis. 2009; 26(2): 153–159. Published online 2008 Nov 5. doi: 10.1007/s10585-008-9225-8

PMCID:: PMC3042857

Abstract Article PDF–256K

Select item 278873312.

The enabled homolog gene polymorphisms are associated with susceptibility and progression of childhood IgA nephropathy

Won-Ho Hahn, Jin-Soon Suh, Byoung-Soo Cho, Sung-Do Kim

Exp Mol Med. 2009 Nov 30; 41(11): 793–801. Published online 2009 Nov 30. doi: 10.3858/emm.2009.41.11.085

PMCID:: PMC2788733

Abstract Article PDF–372K

Select item 117017413.

A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family.

K Niebuhr, F Ebel, R Frank, M Reinhard, E Domann, U D Carl, U Walter, F B Gertler, J Wehland, T Chakraborty

EMBO J. 1997 Sep 1; 16(17): 5433–5444. doi: 10.1093/emboj/16.17.5433

PMCID:: PMC1170174

Summary PDF–651K

Select item 1003654414.

Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression

Frederic Li Mow Chee, Bruno Beernaert, Billie G. C. Griffith, Alexander E. P. Loftus, Yatendra Kumar, Jimi C. Wills, Martin Lee, Jessica Valli, Ann P. Wheeler, J. Douglas Armstrong, Maddy Parsons, Irene M. Leigh, Charlotte M. Proby, Alex von Kriegsheim, Wendy A. Bickmore, Margaret C. Frame, Adam Byron

Nat Commun. 2023; 14: 1602. Published online 2023 Mar 23. doi: 10.1038/s41467-023-37021-x

PMCID:: PMC10036544

Abstract Article PDF–11M

Select item 925735515.

肝细胞癌进展过程中的关键基因ATP1B3和ENAH的筛选与鉴定：基于数据挖掘和临床验证

杨雪佳, 李玉杰, 吴登强, 马义丽, 周素芳

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Jun 20; 42(6): 815–823. Chinese. doi: 10.12122/j.issn.1673-4254.2022.06.04

PMCID:: PMC9257355

Abstract Article PDF–1.8M

Select item 737492016.

Human umbilical cord mesenchymal stem cells-derived exosomes deliver microRNA-375 to downregulate ENAH and thus retard esophageal squamous cell carcinoma progression

Zhanfeng He, Weihao Li, Tianliang Zheng, Donglei Liu, Song Zhao

J Exp Clin Cancer Res. 2020; 39: 140. Published online 2020 Jul 22. doi: 10.1186/s13046-020-01631-w

PMCID:: PMC7374920

Abstract Article PDF–3.9M

Select item 696257717.

Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling

Anthony J. Berger, Carine M. Renner, Isaac Hale, Xinhai Yang, Suzanne M. Ponik, Paul S. Weisman, Kristyn S. Masters, Pamela K. Kreeger

Matrix Biol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Matrix Biol. 2020 Jan; 85-86: 80–93. Published online 2019 Jul 16. doi: 10.1016/j.matbio.2019.07.006

PMCID:: PMC6962577

Abstract Article PDF–2.5M

Select item 509992718.

Mena^INV dysregulates cortactin phosphorylation to promote invadopodium maturation

Maxwell D. Weidmann, Chinmay R. Surve, Robert J. Eddy, Xiaoming Chen, Frank B. Gertler, Ved P. Sharma, John S. Condeelis

Sci Rep. 2016; 6: 36142. Published online 2016 Nov 8. doi: 10.1038/srep36142

PMCID:: PMC5099927

Abstract Article PDF–2.7M

Select item 502108919.

5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

Charles V. Rajadurai, Serhiy Havrylov, Paula P. Coelho, Colin D.H. Ratcliffe, Kossay Zaoui, Bruce H. Huang, Anie Monast, Naila Chughtai, Veena Sangwan, Frank B. Gertler, Peter M. Siegel, Morag Park

J Cell Biol. 2016 Sep 12; 214(6): 719–734. doi: 10.1083/jcb.201501003

PMCID:: PMC5021089

Abstract Article PDF–3.4M

Select item 477768020.

Characterization of the expression of the pro-metastatic Mena^INV isoform during breast tumor progression

Madeleine J. Oudin, Shannon K. Hughes, Nazanin Rohani, Mira N. Moufarrej, Joan G. Jones, John S. Condeelis, Douglas A. Lauffenburger, Frank B. Gertler

Clin Exp Metastasis. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Clin Exp Metastasis. 2016 Mar; 33(3): 249–261. Published online 2015 Dec 17. doi: 10.1007/s10585-015-9775-5