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Select item 62009411.

H₂O₂ oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes

Kimberly J. Nelson, Jesalyn A. Bolduc, Hanzhi Wu, John A. Collins, Elizabeth A. Burke, Julie A. Reisz, Chananat Klomsiri, Scott T. Wood, Raghunatha R. Yammani, Leslie B. Poole, Cristina M. Furdui, Richard F. Loeser

J Biol Chem. 2018 Oct 19; 293(42): 16376–16389. Published online 2018 Sep 6. doi: 10.1074/jbc.RA118.004613

PMCID:: PMC6200941

Abstract Article PDF–2.3M

Select item 59035842.

Role of Stress Kinase JNK in Binge Alcohol-Evoked Atrial Arrhythmia

Jiajie Yan, Justin K. Thomson, Weiwei Zhao, Xianlong Gao, Fei Huang, Biyi Chen, Qingrong Liang, Long-Sheng Song, Michael Fill, Xun Ai

J Am Coll Cardiol. Author manuscript; available in PMC 2018 Apr 17.

Published in final edited form as: J Am Coll Cardiol. 2018 Apr 3; 71(13): 1459–1470. doi: 10.1016/j.jacc.2018.01.060

PMCID:: PMC5903584

Abstract Article PDF–1.5M

Select item 35426033.

JNK2 is activated during ER stress and promotes cell survival

M Raciti, L V Lotti, S Valia, F M Pulcinelli, L Di Renzo

Cell Death Dis. 2012 Nov; 3(11): e429. Published online 2012 Nov 22. doi: 10.1038/cddis.2012.167

PMCID:: PMC3542603

Abstract Article PDF–2.0M

Select item 3593764.

Signal transduction by tumor necrosis factor mediated by JNK protein kinases.

H K Sluss, T Barrett, B Dérijard, R J Davis

Mol Cell Biol. 1994 Dec; 14(12): 8376–8384. doi: 10.1128/mcb.14.12.8376

PMCID:: PMC359376

Summary Page Browse PDF–2.2M

Select item 853545.

Inhibition of c-Jun N-Terminal Kinase 2 Expression Suppresses Growth and Induces Apoptosis of Human Tumor Cells in a p53-Dependent Manner

Olga Potapova, Myriam Gorospe, Ryan H. Dougherty, Nicholas M. Dean, William A. Gaarde, Nikki J. Holbrook

Mol Cell Biol. 2000 Mar; 20(5): 1713–1722. doi: 10.1128/mcb.20.5.1713-1722.2000

PMCID:: PMC85354

Abstract Article PDF–2.0M

Select item 293326.

Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)

Axel Behrens, Kanaga Sabapathy, Isabella Graef, Mike Cleary, Gerald R. Crabtree, Erwin F. Wagner

Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4): 1769–1774. doi: 10.1073/pnas.98.4.1769

PMCID:: PMC29332

Abstract Article PDF–240K

Select item 87615717.

c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1

Xiaodong Tian, Benno Traub, Jingwei Shi, Nadine Huber, Stefan Schreiner, Guowei Chen, Shaoxia Zhou, Doris Henne-Bruns, Uwe Knippschild, Marko Kornmann

Cancer Gene Ther. 2022; 29(1): 73–86. Published online 2021 Feb 1. doi: 10.1038/s41417-020-00290-5

PMCID:: PMC8761571

Abstract Article PDF–6.5M

Select item 71813038.

JNK2 Is Required for the Tumorigenic Properties of Melanoma Cells

Lili Du, Anna Anderson, Kimberly Nguyen, Sandra S. Ojeda, Ivannie Ortiz-Rivera, Tran Ngoc Nguyen, Tinghu Zhang, Tamer S. Kaoud, Nathanael S. Gray, Kevin N. Dalby, Kenneth Y. Tsai

ACS Chem Biol. Author manuscript; available in PMC 2020 Jul 19.

Published in final edited form as: ACS Chem Biol. 2019 Jul 19; 14(7): 1426–1435. Published online 2019 May 17. doi: 10.1021/acschembio.9b00083

PMCID:: PMC7181303

Abstract Article PDF–1.6M

Select item 56619749.

The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis

RT Nitta, CA Del Vecchio, AH Chu, SS Mitra, AK Godwin, AJ Wong

Oncogene. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Oncogene. 2011 Jan 13; 30(2): 234–244. Published online 2010 Sep 27. doi: 10.1038/onc.2010.414

PMCID:: PMC5661974

Abstract Article PDF–875K

Select item 502681510.

Down-regulation of miR-20a-5p triggers cell apoptosis to facilitate mycobacterial clearance through targeting JNK2 in human macrophages

Guoliang Zhang, Xi Liu, Wenfei Wang, Yi Cai, Shaoyuan Li, Qi Chen, Mingfeng Liao, Mingxia Zhang, Gucheng Zeng, Boping Zhou, Carl G. Feng, Xinchun Chen

Cell Cycle. 2016; 15(18): 2527–2538. Published online 2016 Aug 5. doi: 10.1080/15384101.2016.1215386

PMCID:: PMC5026815

Abstract Article PDF–1.2M

Select item 498207211.

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells

Irina Neganova, Evgenija Shmeleva, Jennifer Munkley, Valeria Chichagova, George Anyfantis, Rhys Anderson, Joao Passos, David J. Elliott, Lyle Armstrong, Majlinda Lako

Stem Cells. 2016 May; 34(5): 1198–1212. Published online 2016 Mar 4. doi: 10.1002/stem.2327

PMCID:: PMC4982072

Abstract Article PDF–1.4M

Select item 481371712.

Palmitic acid induces autophagy in hepatocytes via JNK2 activation

Qian-qian Tu, Rui-ying Zheng, Juan Li, Liang Hu, Yan-xin Chang, Liang Li, Min-hong Li, Ruo-yu Wang, Dan-dan Huang, Meng-chao Wu, He-ping Hu, Lei Chen, Hong-yang Wang

Acta Pharmacol Sin. 2014 Apr; 35(4): 504–512. Published online 2014 Mar 10. doi: 10.1038/aps.2013.170

PMCID:: PMC4813717

Abstract Article PDF–3.0M

Select item 456197413.

JNK is required for maintaining the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells

Yuan Liu, Xia Zhang, Juan Wang, Jun Yang, Wen-fu Tan

Acta Pharmacol Sin. 2015 Sep; 36(9): 1099–1106. Published online 2015 Aug 3. doi: 10.1038/aps.2015.58

PMCID:: PMC4561974

Abstract Article PDF–1.4M

Select item 407576414.

AKT/mTOR and C-Jun N-terminal Kinase (JNK) Signaling Pathways Are Required for Chrysotile Asbestos-Induced Autophagy

Ziying Lin, Tie Liu, David W Kamp, Yahong Wang, Huijuan He, Xu Zhou, Donghong Li, Lawei Yang, Bin Zhao, Gang Liu

Free Radic Biol Med. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Free Radic Biol Med. 2014 Jul; 72: 296–307. Published online 2014 Apr 13. doi: 10.1016/j.freeradbiomed.2014.04.004

PMCID:: PMC4075764

Abstract Article PDF–995K

Select item 368170715.

JNK1/2 regulates ER–mitochondrial Ca²⁺ cross-talk during IL-1β–mediated cell death in RINm5F and human primary β-cells

Gaurav Verma, Himanshi Bhatia, Malabika Datta

Mol Biol Cell. 2013 Jun 15; 24(12): 2058–2071. doi: 10.1091/mbc.E12-12-0885

PMCID:: PMC3681707

Abstract Article PDF–3.2M

Select item 364645416.

A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes

Minoru Ito, Michiaki Nagasawa, Naoki Omae, Masaki Tsunoda, Junichi Ishiyama, Tomohiro Ide, Yunike Akasaka, Koji Murakami

J Lipid Res. 2013 Jun; 54(6): 1531–1540. doi: 10.1194/jlr.M031591

PMCID:: PMC3646454

Abstract Article PDF–1.0M

Select item 327553917.

Effect of ulinastatin on growth inhibition, apoptosis of breast carcinoma cells is related to a decrease in signal conduction of JNk-2 and NF-κB

Hong Wang, Xin Sun, Feng Gao, Biao Zhong, Yong-hua Zhang, Zhijun Sun

J Exp Clin Cancer Res. 2012; 31(1): 2. Published online 2012 Jan 5. doi: 10.1186/1756-9966-31-2

PMCID:: PMC3275539

Abstract Article PDF–4.6M

Select item 320592818.

Ultra Fine Particles from Diesel Engines Induce Vascular Oxidative Stress via JNK Activation

Rongsong Li, Zhi Ning, Jeffery Cui, Bhavraj Khalsa, Lisong Ai, Wakako Takabe, Tyler Beebe, Rohit Majumdar, Constantinos Sioutas, Tzung Hsiai

Free Radic Biol Med. Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Free Radic Biol Med. 2009 Mar 15; 46(6): 775–782. Published online 2008 Dec 11. doi: 10.1016/j.freeradbiomed.2008.11.025