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Select item 100030651.

Impact of Acute High Glucose on Mitochondrial Function in a Model of Endothelial Cells: Role of PDGF-C

Adriana Grismaldo Rodríguez, Jairo Zamudio Rodríguez, Alfonso Barreto, Sandra Sanabria-Barrera, José Iglesias, Ludis Morales

Int J Mol Sci. 2023 Mar; 24(5): 4394. Published online 2023 Feb 23. doi: 10.3390/ijms24054394

PMCID:: PMC10003065

Abstract Article PDF–2.6M

Select item 68729462.

An oncogenic activity of PDGF-C and its splice variant in human breast cancer

Alyssa Bottrell, Yong Hong Meng, Abdo J. Najy, Newton Hurst, Jr., Seongho Kim, Chong Jai Kim, Eun-Sook Kim, Aree Moon, Eun Joo Kim, So Yeon Park, Hyeong-Reh Choi Kim

Growth Factors. Author manuscript; available in PMC 2020 Sep 23.

Published in final edited form as: Growth Factors. 2019 Aug; 37(3-4): 131–145. Published online 2019 Sep 23. doi: 10.1080/08977194.2019.1662415

PMCID:: PMC6872946

Abstract Article PDF–1.5M

Select item 48391683.

Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration

Sebastian A. Lewandowski, Ingrid Nilsson, Linda Fredriksson, Peter Lönnerberg, Lars Muhl, Manuel Zeitelhofer, Milena Z. Adzemovic, Susanne Nichterwitz, Daniel A. Lawrence, Eva Hedlund, Ulf Eriksson

Acta Neuropathol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Acta Neuropathol. 2016 Mar; 131(3): 453–464. Published online 2015 Dec 19. doi: 10.1007/s00401-015-1520-2

PMCID:: PMC4839168

Abstract Article PDF–903K

Select item 38607484.

PDGF-C is an EWS/FLI induced transforming growth factor in Ewing Family Tumors

Jeffrey P. Zwerner, William A. May

Oncogene. Author manuscript; available in PMC 2013 Dec 12.

Published in final edited form as: Oncogene. 2001 Feb 1; 20(5): 10.1038/sj.onc.1204133. doi: 10.1038/sj.onc.1204133

PMCID:: PMC3860748

Abstract Article PDF–2.2M

Select item 34609005.

Maternal Transmission Effect of a PDGF-C SNP on Nonsyndromic Cleft Lip with or without Palate from a Chinese Population

Di Wu, Mei Wang, Xingang Wang, Ningbei Yin, Tao Song, Haidong Li, Feng Zhang, Yongbiao Zhang, Zhenqing Ye, Jun Yu, Duen-Mei Wang, Zhenmin Zhao

PLoS One. 2012; 7(9): e46477. Published online 2012 Sep 28. doi: 10.1371/journal.pone.0046477

PMCID:: PMC3460900

Abstract Article PDF–376K

Select item 27978176.

Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas

Ove Bruland, Øystein Fluge, Lars A Akslen, Hans G Eiken, Johan R Lillehaug, Jan E Varhaug, Per M Knappskog

BMC Cancer. 2009; 9: 425. Published online 2009 Dec 8. doi: 10.1186/1471-2407-9-425

PMCID:: PMC2797817

Abstract Article PDF–1.5M

Select item 27887487.

The PDGF-C regulatory region SNP rs28999109 decreases promoter transcriptional activity and is associated with CL/P

Sun J Choi, Mary L Marazita, P Suzanne Hart, Pawel P Sulima, L Leigh Field, Toby Goldstein McHenry, Manika Govil, Margaret E Cooper, Ariadne Letra, Renato Menezes, Somnya Narayanan, Maria Adela Mansilla, José M Granjeiro, Alexandre R Vieira, Andrew C Lidral, Jeffrey C Murray, Thomas C Hart

Eur J Hum Genet. 2009 Jun; 17(6): 774–784. Published online 2008 Dec 17. doi: 10.1038/ejhg.2008.245

PMCID:: PMC2788748

Abstract Article PDF–240K

Select item 27548888.

Platelet-Derived Growth Factor C Is Upregulated in Human Uterine Fibroids and Regulates Uterine Smooth Muscle Cell Growth

Guangli Suo, Yong Jiang, Bryan Cowan, Jean Y.J. Wang

Biol Reprod. 2009 Oct; 81(4): 749–758. Published online 2009 Jun 24. doi: 10.1095/biolreprod.109.076869

PMCID:: PMC2754888

Abstract Article PDF–4.1M

Select item 86337839.

Expression and function of PDGF-C in development and stem cells

Yi Tian, Ying Zhan, Qin Jiang, Weisi Lu, Xuri Li

Open Biol. 2021 Dec; 11(12): 210268. Published online December 1, 2021. doi: 10.1098/rsob.210268

PMCID:: PMC8633783

Abstract Article PDF–982K

Select item 589672910.

Microenvironmental control of breast cancer subtype elicited by paracrine platelet derived growth factor-CC signaling

Pernilla Roswall, Matteo Bocci, Michael Bartoschek, Hong Li, Glen Kristiansen, Sara Jansson, Sophie Lehn, Jonas Sjölund, Steven Reid, Christer Larsson, Pontus Eriksson, Charlotte Anderberg, Eliane Cortez, Lao H Saal, Christina Orsmark-Pietras, Eugenia Cordero, B Kristian Haller, Jari Häkkinen, Ingrid JG Burvenich, Elgene Lim, Akira Orimo, Mattias Höglund, Lisa Rydén, Holger Moch, Andrew M Scott, Ulf Eriksson, Kristian Pietras

Nat Med. Author manuscript; available in PMC 2018 Sep 12.

Published in final edited form as: Nat Med. 2018 May; 24(4): 463–473. Published online 2018 Mar 12. doi: 10.1038/nm.4494

PMCID:: PMC5896729

Abstract Article PDF–2.7M

Select item 537310111.

Genetic Variants in MicroRNA Biosynthesis Pathways and Binding Sites Modify Ovarian Cancer Risk, Survival, and Treatment Response

Dong Liang, Larissa Meyer, David W. Chang, Jie Lin, Xia Pu, Yuanqing Ye, Jian Gu, Xifeng Wu, Karen Lu

Cancer Res. Author manuscript; available in PMC 2017 Mar 30.

Published in final edited form as: Cancer Res. 2010 Dec 1; 70(23): 9765–9776. Published online 2010 Nov 30. doi: 10.1158/0008-5472.CAN-10-0130

PMCID:: PMC5373101

Abstract Article PDF–549K

Select item 426416812.

Post-Transcriptional Up-Regulation of PDGF-C by HuR in Advanced and Stressed Breast Cancer

Nian-An Luo, Ya-Qi Qu, Guo-Dong Yang, Tao Wang, Ren-Li Li, Lin-Tao Jia, Rui Dong

Int J Mol Sci. 2014 Nov; 15(11): 20306–20320. Published online 2014 Nov 6. doi: 10.3390/ijms151120306

PMCID:: PMC4264168

Abstract Article PDF–1.8M

Select item 55294013.

Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma

Jean S. Campbell, Steven D. Hughes, Debra G. Gilbertson, Thomas E. Palmer, Matthew S. Holdren, Aaron C. Haran, Melissa M. Odell, Renay L. Bauer, Hong-Ping Ren, Harald S. Haugen, Matthew M. Yeh, Nelson Fausto

Proc Natl Acad Sci U S A. 2005 Mar 1; 102(9): 3389–3394. Published online 2005 Feb 22. doi: 10.1073/pnas.0409722102

PMCID:: PMC552940

Abstract Article PDF–701K

Select item 1088055514.

MicroRNA-29a inhibits glioblastoma stem cells and tumor growth by regulating the PDGF pathway

Yanzhi Yang, Samantha Dodbele, Thomas Park, Rainer Glass, Krishna Bhat, Erik P. Sulman, Ying Zhang, Roger Abounader

J Neurooncol. Author manuscript; available in PMC 2024 Feb 21.

Published in final edited form as: J Neurooncol. 2019 Oct; 145(1): 23–34. Published online 2019 Sep 3. doi: 10.1007/s11060-019-03275-z

PMCID:: PMC10880555

Abstract Article PDF–1.3M

Select item 910657715.

RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m⁶A-YTHDF2-dependent manner

Zhen Tan, Si Shi, Jin Xu, Xiaomeng Liu, Yubin Lei, Bo Zhang, Jie Hua, Qingcai Meng, Wei Wang, Xianjun Yu, Chen Liang

Oncogene. 2022; 41(20): 2860–2872. Published online 2022 Apr 14. doi: 10.1038/s41388-022-02306-w

PMCID:: PMC9106577

Abstract Article PDF–5.5M

Select item 797954016.

Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis

Hyunho Yoon, Chih-Min Tang, Sudeep Banerjee, Mayra Yebra, Sangkyu Noh, Adam M. Burgoyne, Jorge De la Torre, Martina De Siena, Mengyuan Liu, Lillian R. Klug, Yoon Young Choi, Mojgan Hosseini, Antonio L. Delgado, Zhiyong Wang, Randall P. French, Andrew Lowy, Ronald P. DeMatteo, Michael C. Heinrich, Alfredo A. Molinolo, J. Silvio Gutkind, Olivier Harismendy, Jason K. Sicklick

Oncogene. 2021; 40(11): 1957–1973. Published online 2021 Feb 18. doi: 10.1038/s41388-021-01685-w

PMCID:: PMC7979540

Abstract Article PDF–7.2M

Select item 594574617.

The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence

Sara Jansson, Kristina Aaltonen, Pär-Ola Bendahl, Anna-Karin Falck, Maria Karlsson, Kristian Pietras, Lisa Rydén

Breast Cancer Res Treat. 2018; 169(2): 231–241. Published online 2018 Jan 29. doi: 10.1007/s10549-018-4664-7

PMCID:: PMC5945746

Abstract Article PDF–1.2M

Select item 393768718.

Platelet-derived Growth Factor-C (PDGF-C) Induces Anti-apoptotic Effects on Macrophages through Akt and Bad Phosphorylation

Dain Son, Yi Rang Na, Eung-Soo Hwang, Seung Hyeok Seok

J Biol Chem. 2014 Feb 28; 289(9): 6225–6235. Published online 2014 Jan 13. doi: 10.1074/jbc.M113.508994

PMCID:: PMC3937687

Abstract Article PDF–1.7M

Select item 387696619.

Paracrine activation of hepatic stellate cells in platelet-derived growth factor C transgenic mice; evidence for stromal induction of hepatocellular carcinoma

Jocelyn H Wright, Melissa M. Johnson, Masami Shimizu-Albergine, Renay L. Bauer, Brian J. Hayes, James Surapisitchat, Kelly L. Hudkins, Kimberly J. Riehle, Simon Johnson, Matthew M. Yeh, Theodor K. Bammler, Richard P. Beyer, Deb G. Gilbertson, Charles C. Alpers, Nelson Fausto, Jean S. Campbell

Int J Cancer. Author manuscript; available in PMC 2015 Feb 15.

Published in final edited form as: Int J Cancer. 2014 Feb 15; 134(4): 778–788. Published online 2013 Sep 16. doi: 10.1002/ijc.28421

PMCID:: PMC3876966

Abstract Article PDF–8.3M

Select item 481488720.

High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cells

Hiroya Kitsunai, Yuichi Makino, Hidemitsu Sakagami, Katsutoshi Mizumoto, Tsuyoshi Yanagimachi, Kuralay Atageldiyeva, Yasutaka Takeda, Yukihiro Fujita, Atsuko Abiko, Yumi Takiyama, Masakazu Haneda

Physiol Rep. 2016 Mar; 4(6): e12730. Published online 2016 Mar 31. doi: 10.14814/phy2.12730

PMCID:: PMC4814887

Abstract Article PDF–2.3M

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