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Select item 102014401.

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

Parasvi S Patel, Arash Algouneh, Rehna Krishnan, John J Reynolds, Kevin C J Nixon, Jun Hao, Jihoon Lee, Yue Feng, Chehronai Fozil, Mia Stanic, Talya Yerlici, Peiran Su, Fraser Soares, Elisabeth Liedtke, Gil Prive, Gary D Baider, Miquel Angel Pujana, Karim Mekhail, Housheng Hansen He, Anne Hakem, Grant S Stewart, Razqallah Hakem

Nucleic Acids Res. 2023 May 22; 51(9): 4341–4362. Published online 2023 Mar 17. doi: 10.1093/nar/gkad172

PMCID:: PMC10201440

Abstract Article PDF–4.5M

Select item 68387582.

HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb

Alessandro Furlan, Mariano Gonzalez-Pisfil, Aymeric Leray, Dorian Champelovier, Mélanie Henry, Corentin Le Nézet, Oliver Bensaude, Marc Lefranc, Thorsten Wohland, Bernard Vandenbunder, Gabriel Bidaux, Laurent Héliot

Biophys J. 2019 Nov 5; 117(9): 1615–1625. Published online 2019 Sep 20. doi: 10.1016/j.bpj.2019.09.019

PMCID:: PMC6838758

Abstract Article PDF–1.0M

Select item 63395793.

Structural basis of 7SK RNA 5′ γ-phosphate methylation and retention by MePCE

Yuan Yang, Catherine D. Eichhorn, Yaqiang Wang, Duilio Cascio, Juli Feigon

Nat Chem Biol. Author manuscript; available in PMC 2019 Jun 17.

Published in final edited form as: Nat Chem Biol. 2019 Feb; 15(2): 132–140. Published online 2018 Dec 17. doi: 10.1038/s41589-018-0188-z

PMCID:: PMC6339579

Abstract Article PDF–2.6M

Select item 20770244.

Human capping enzyme promotes formation of transcriptional R loops in vitro

Syuzo Kaneko, Chun Chu, Aaron J. Shatkin, James L. Manley

Proc Natl Acad Sci U S A. 2007 Nov 6; 104(45): 17620–17625. Published online 2007 Oct 31. doi: 10.1073/pnas.0708866104

PMCID:: PMC2077024

Abstract Article PDF–546K

Select item 112508285.

LARP3, LARP7, and MePCE are involved in the early stage of human telomerase RNA biogenesis

Tsai-Ling Kao, Yu-Cheng Huang, Yi-Hsuan Chen, Peter Baumann, Chi-Kang Tseng

Nat Commun. 2024; 15: 5955. Published online 2024 Jul 15. doi: 10.1038/s41467-024-50422-w

PMCID:: PMC11250828

Abstract Article PDF–2.9M

Select item 77098166.

Long non-coding RNA ST8SIA6-AS1 promotes the migration and invasion of hypoxia-treated hepatocellular carcinoma cells through the miR-338/MEPCE axis

Bin Zhang, Zhiyi Liu, Jin Liu, Kuan Cao, Wengang Shan, Quan Wen, Renhao Wang

Oncol Rep. 2021 Jan; 45(1): 73–82. Published online 2020 Nov 20. doi: 10.3892/or.2020.7864

PMCID:: PMC7709816

Abstract Article PDF–1.3M

Select item 28110267.

A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP

Yuhua Xue, Zhiyuan Yang, Ruichuan Chen, Qiang Zhou

Nucleic Acids Res. 2010 Jan; 38(2): 360–369. Published online 2009 Nov 11. doi: 10.1093/nar/gkp977

PMCID:: PMC2811026

Abstract Article PDF–3.5M

Select item 54997378.

Reconstitution of a functional 7SK snRNP

John E. Brogie, David H. Price

Nucleic Acids Res. 2017 Jun 20; 45(11): 6864–6880. Published online 2017 Apr 20. doi: 10.1093/nar/gkx262

PMCID:: PMC5499737

Abstract Article PDF–4.8M

Select item 53769719.

The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression

Sylvain Egloff, Patrice Vitali, Michael Tellier, Raoul Raffel, Shona Murphy, Tamás Kiss

EMBO J. 2017 Apr 3; 36(7): 934–948. Published online 2017 Mar 2. doi: 10.15252/embj.201695740

PMCID:: PMC5376971

Abstract Article PDF–1.2M

Select item 236771710.

LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

Brian J. Krueger, Célia Jeronimo, Bibhuti Bhusan Roy, Annie Bouchard, Charlotte Barrandon, Sarah A. Byers, Courtney E. Searcey, Jeffrey J. Cooper, Olivier Bensaude, Éric A. Cohen, Benoit Coulombe, David H. Price

Nucleic Acids Res. 2008 Apr; 36(7): 2219–2229. Published online 2008 Feb 16. doi: 10.1093/nar/gkn061

PMCID:: PMC2367717

Abstract Article PDF–6.7M

Select item 648243311.

P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress

Andrii Bugai, Alexandre J.C. Quaresma, Caroline C. Friedel, Tina Lenasi, Robert Düster, Christopher R. Sibley, Koh Fujinaga, Petra Kukanja, Thomas Hennig, Melanie Blasius, Matthias Geyer, Jernej Ule, Lars Dölken, Matjaž Barborič

Mol Cell. 2019 Apr 18; 74(2): 254–267.e10. doi: 10.1016/j.molcel.2019.01.033

PMCID:: PMC6482433

Abstract Article

Select item 242738112.

Andreas Markert, Michael Grimm, Javier Martinez, Julia Wiesner, Andreas Meyerhans, Oded Meyuhas, Albert Sickmann, Utz Fischer

EMBO Rep. 2008 Jun; 9(6): 569–575. Published online 2008 May 16. doi: 10.1038/embor.2008.72

PMCID:: PMC2427381

Abstract Article PDF–219K

Select item 388231713.

Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation

Ryan P. McNamara, Jennifer L. McCann, Swapna Aravind Gudipaty, Iván D’Orso

Cell Rep. Author manuscript; available in PMC 2014 Dec 12.

Published in final edited form as: Cell Rep. 2013 Dec 12; 5(5): 10.1016/j.celrep.2013.11.003. Published online 2013 Dec 5. doi: 10.1016/j.celrep.2013.11.003