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Select item 63183881.

CD56 and CD11b Positivity with Low Smac/DIABLO Expression as Predictors of Chemoresistance in Acute Myeloid Leukaemia: Flow Cytometric Analysis

Abeer Ibrahim, Asmaa M Zahran, Sanaa Shaker Aly, Ahmed Refaat, Mohammed H Hassan

Asian Pac J Cancer Prev. 2018; 19(11): 3187–3192. doi: 10.31557/APJCP.2018.19.11.3187

PMCID:: PMC6318388

Abstract Article PDF–356K

Select item 59106712.

A New Role for the Mitochondrial Pro-apoptotic Protein SMAC/Diablo in Phospholipid Synthesis Associated with Tumorigenesis

Avijit Paul, Yakov Krelin, Tasleem Arif, Rina Jeger, Varda Shoshan-Barmatz

Mol Ther. 2018 Mar 7; 26(3): 680–694. Published online 2017 Dec 24. doi: 10.1016/j.ymthe.2017.12.020

PMCID:: PMC5910671

Abstract Article PDF–6.8M

Select item 55709343.

Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms

Dae-Sun Kim, Himika Dastidar, Chunfen Zhang, Franz J. Zemp, Keith Lau, Matthias Ernst, Andrea Rakic, Saif Sikdar, Jahanara Rajwani, Victor Naumenko, Dale R. Balce, Ben W. Ewanchuk, Pankaj Tailor, Robin M. Yates, Craig Jenne, Chris Gafuik, Douglas J. Mahoney

Nat Commun. 2017; 8: 344. Published online 2017 Aug 24. doi: 10.1038/s41467-017-00324-x

Correction in:: Nat Commun. 2018; 9: 2109.

PMCID:: PMC5570934

Abstract Article PDF–869K

Select item 55021744.

Downregulation of Smac attenuates H₂O₂-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells

Kong De-qian, Liu Yue, Li Li, Zheng Guangying

Medicine (Baltimore) 2017 Jul; 96(27): e7419. Published online 2017 Jul 7. doi: 10.1097/MD.0000000000007419

PMCID:: PMC5502174

Abstract Article PDF–434K

Select item 54868465.

Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)

Rama Rathore, Jennifer E. McCallum, Elizabeth Varghese, Ana-Maria Florea, Dietrich Büsselberg

Apoptosis. 2017; 22(7): 898–919. Published online 2017 Apr 19. doi: 10.1007/s10495-017-1375-1

PMCID:: PMC5486846

Abstract Article PDF–1.4M

Select item 51299456.

Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic

Kumudha Balakrishnan, Min Fu, Francesco Onida, William G. Wierda, Michael J. Keating, Varsha Gandhi

Oncotarget. 2016 Jun 28; 7(26): 39458–39472. Published online 2016 Mar 29. doi: 10.18632/oncotarget.8462

PMCID:: PMC5129945

Abstract Article PDF–4.2M

Select item 43175477.

The Activator of Apoptosis Smac-DIABLO Acts as a Tetramer in Solution

Eloise Mastrangelo, Patrice Vachette, Federica Cossu, Francesca Malvezzi, Martino Bolognesi, Mario Milani

Biophys J. 2015 Feb 3; 108(3): 714–723. doi: 10.1016/j.bpj.2014.11.3471

PMCID:: PMC4317547

Abstract Article PDF–1.4M

Select item 42031648.

Ectopic expression of new alternative splice variant of Smac/DIABLO increases mammospheres formation

Gustavo U Martinez-Ruiz, Georgina Victoria-Acosta, Karla I Vazquez-Santillan, Luis Jimenez-Hernandez, Laura Muñoz-Galindo, Gisela Ceballos-Cancino, Vilma Maldonado, Jorge Melendez-Zajgla

Int J Clin Exp Pathol. 2014; 7(9): 5515–5526. Published online 2014 Aug 15.

PMCID:: PMC4203164

Abstract Article PDF–1.4M

Select item 36184959.

The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells

Clemens Krepler, Srinivas K. Chunduru, Molly B. Halloran, Xu He, Min Xiao, Adina Vultur, Jessie Villanueva, Yasuhiro Mitsuuchi, Eric M. Neiman, Christopher Benetatos, Katherine L. Nathanson, Ravi K. Amaravadi, Hubert Pehamberger, Mark McKinlay, Meenhard Herlyn

Clin Cancer Res. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Clin Cancer Res. 2013 Apr 1; 19(7): 1784–1794. Published online 2013 Feb 12. doi: 10.1158/1078-0432.CCR-12-2518

PMCID:: PMC3618495

Abstract Article PDF–2.7M

Select item 361572810.

Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells

A Tchoghandjian, C Jennewein, I Eckhardt, K Rajalingam, S Fulda

Cell Death Dis. 2013 Mar; 4(3): e564. Published online 2013 Mar 28. doi: 10.1038/cddis.2013.70

PMCID:: PMC3615728

Abstract Article PDF–1.9M

Select item 358457511.

Low circulating serum levels of second mitochondria-derived activator of caspase (Smac/DIABLO) in patients with bladder cancer

YOICHI MIZUTANI, YOJI KATSUOKA, BENJAMIN BONAVIDA

Int J Oncol. 2012 Apr; 40(4): 1246–1250. Published online 2012 Jan 3. doi: 10.3892/ijo.2012.1324

PMCID:: PMC3584575

Abstract Article PDF–323K

Select item 351988212.

Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

Shuijun Zhang, Gongquan Li, Yongfu Zhao, Guangzhi Liu, Yu Wang, Xiuxian Ma, Dexu Li, Yang Wu, Jianfeng Lu

PLoS One. 2012; 7(12): e51461. Published online 2012 Dec 11. doi: 10.1371/journal.pone.0051461

PMCID:: PMC3519882

Abstract Article PDF–799K

Select item 340709213.

Application of Flow Cytometry to Determine Differential Redistribution of Cytochrome c and Smac/DIABLO from Mitochondria during Cell Death Signaling

Heling Ng, Danielle J. Smith, Phillip Nagley

PLoS One. 2012; 7(7): e42298. Published online 2012 Jul 27. doi: 10.1371/journal.pone.0042298

PMCID:: PMC3407092

Abstract Article PDF–895K

Select item 307900914.

Smac Modulates Chemosensitivity in Head and Neck Cancer Cells through the Mitochondrial Apoptotic Pathway

Quanhong Sun, Xingnan Zheng, Lin Zhang, Jian Yu

Clin Cancer Res. Author manuscript; available in PMC 2012 Apr 15.

Published in final edited form as: Clin Cancer Res. 2011 Apr 15; 17(8): 2361–2372. Published online 2011 Jan 17. doi: 10.1158/1078-0432.CCR-10-2262

PMCID:: PMC3079009

Abstract Article PDF–1.6M

Select item 218552515.

The Inhibitor of Apoptosis Protein-Binding Domain of Smac Is Not Essential for Its Proapoptotic Activity

Darren L. Roberts, Wendy Merrison, Marion MacFarlane, Gerald M. Cohen

J Cell Biol. 2001 Apr 2; 153(1): 221–228. doi: 10.1083/jcb.153.1.221

PMCID:: PMC2185525

Abstract Article PDF–331K

Select item 217283716.

Real-time single cell analysis of Smac/DIABLO release during apoptosis

Markus Rehm, Heiko Düßmann, Jochen H.M. Prehn

J Cell Biol. 2003 Sep 15; 162(6): 1031–1043. doi: 10.1083/jcb.200303123

PMCID:: PMC2172837

Abstract Article PDF–1021K

Select item 20763317.

Fibroblast Growth Factor 2-Mediated Translational Control of IAPs Blocks Mitochondrial Release of Smac/DIABLO and Apoptosis in Small Cell Lung Cancer Cells

Olivier E. Pardo, Adeline Lesay, Alexandre Arcaro, Rita Lopes, Bee Ling Ng, Patricia H. Warne, Iain A. McNeish, Teresa D. Tetley, Nicholas R. Lemoine, Huseyin Mehmet, Michael J. Seckl, Julian Downward

Mol Cell Biol. 2003 Nov; 23(21): 7600–7610. doi: 10.1128/MCB.23.21.7600-7610.2003