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Select item 112872551.

Conformational dynamics underlying atypical chemokine receptor 3 activation

Omolade Otun, Christelle Aljamous, Elise Del Nero, Marta Arimont-Segura, Reggie Bosma, Barbara Zarzycka, Tristan Girbau, Cédric Leyrat, Chris de Graaf, Rob Leurs, Thierry Durroux, Sébastien Granier, Xiaojing Cong, Cherine Bechara

Proc Natl Acad Sci U S A. 2024 Jul 23; 121(30): e2404000121. Published online 2024 Jul 15. doi: 10.1073/pnas.2404000121

PMCID:: PMC11287255

Abstract Article PDF–5.9M

Select item 102733212.

CXCR7 as a novel therapeutic target for advanced prostate cancer

Galina Gritsina, Jindan Yu

Oncogene. Author manuscript; available in PMC 2023 Jun 16.

Published in final edited form as: Oncogene. 2023 Mar; 42(11): 785–792. Published online 2023 Feb 9. doi: 10.1038/s41388-023-02597-7

PMCID:: PMC10273321

Abstract Article PDF–557K

Select item 102287903.

Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells

Elena C. Sigmund, Aline Bauer, Barbara D. Jakobs, Hazal Tatliadim, Carlotta Tacconi, Marcus Thelen, Daniel F. Legler, Cornelia Halin

PLoS One. 2023; 18(5): e0285597. Published online 2023 May 30. doi: 10.1371/journal.pone.0285597

PMCID:: PMC10228790

Abstract Article PDF–2.6M

Select item 92769394.

Emerging Roles of the Atypical Chemokine Receptor 3 (ACKR3) in Cardiovascular Diseases

Vincent Duval, Paul Alayrac, Jean-Sébastien Silvestre, Angélique Levoye

Front Endocrinol (Lausanne) 2022; 13: 906586. Published online 2022 Jun 29. doi: 10.3389/fendo.2022.906586

PMCID:: PMC9276939

Abstract Article PDF–2.5M

Select item 92237545.

Selective Elimination of Senescent Fibroblasts by Targeting the Cell Surface Protein ACKR3

Kento Takaya, Toru Asou, Kazuo Kishi

Int J Mol Sci. 2022 Jun; 23(12): 6531. Published online 2022 Jun 10. doi: 10.3390/ijms23126531

PMCID:: PMC9223754

Abstract Article PDF–1.6M

Select item 83691846.

Overexpression of CXCR7 is a Novel Indicator for Enzalutamide Resistance in Castration-Resistant Prostate Cancer Patients

Yong Luo, Qiankun Li, Xiaobing Yang, Dechao Wei, Bingfu Feng, Mingchuan Li, Yili Han, Jiahui Zhao, Yunhua Lin, Qing Li, Zhu Hou, Hongyu Zhuang, Yongguang Jiang

Dis Markers. 2021; 2021: 6649579. Published online 2021 Aug 6. doi: 10.1155/2021/6649579

PMCID:: PMC8369184

Abstract Article PDF–733K

Select item 81696477.

The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7

Martyna Szpakowska, Ann M. Decker, Max Meyrath, Christie B. Palmer, Bruce E. Blough, Ojas A. Namjoshi, Andy Chevigné

Signal Transduct Target Ther. 2021; 6: 209. Published online 2021 Jun 2. doi: 10.1038/s41392-021-00548-w

PMCID:: PMC8169647

Article PDF–1005K

Select item 80021798.

Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization

Aurélien Zarca, Claudia Perez, Jelle van den Bor, Jan Paul Bebelman, Joyce Heuninck, Rianna J. F. de Jonker, Thierry Durroux, Henry F. Vischer, Marco Siderius, Martine J. Smit

Cells. 2021 Mar; 10(3): 618. Published online 2021 Mar 11. doi: 10.3390/cells10030618

PMCID:: PMC8002179

Abstract Article PDF–4.0M

Select item 76145379.

Structural snapshot of a β-arrestin-biased receptor

Parishmita Sarma, Ramanuj Banerjee, Arun K. Shukla

Trends Pharmacol Sci. Author manuscript; available in PMC 2023 May 15.

Published in final edited form as: Trends Pharmacol Sci. 2023 Jan 1; 44(1): 1–3. Published online 2022 Aug 31. doi: 10.1016/j.tips.2022.08.005

PMCID:: PMC7614537

Abstract Article PDF–680K

Select item 760376710.

Overexpression of CXCR7 accelerates tumor growth and metastasis of lung cancer cells

Huan Liu, Qian Cheng, Dong-sheng Xu, Wen Wang, Zheng Fang, Dong-dong Xue, Ya Zheng, Alex H. Chang, Yan-jun Lei

Respir Res. 2020; 21: 287. Published online 2020 Oct 31. doi: 10.1186/s12931-020-01518-6

PMCID:: PMC7603767

Abstract Article PDF–2.6M

Select item 748755211.

Shear stress improves the endothelial progenitor cell function via the CXCR7/ERK pathway axis in the coronary artery disease cases

Hua Zhou, Qiang Tu, Yan Zhang, Hua Qiang Xie, Qing Yun Shuai, Xiao Chuan Huang, Jie Fu, Zheng Cao

BMC Cardiovasc Disord. 2020; 20: 403. Published online 2020 Sep 7. doi: 10.1186/s12872-020-01681-0

PMCID:: PMC7487552

Abstract Article PDF–1.3M

Select item 730523612.

The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

Max Meyrath, Martyna Szpakowska, Julian Zeiner, Laurent Massotte, Myriam P. Merz, Tobias Benkel, Katharina Simon, Jochen Ohnmacht, Jonathan D. Turner, Rejko Krüger, Vincent Seutin, Markus Ollert, Evi Kostenis, Andy Chevigné

Nat Commun. 2020; 11: 3033. Published online 2020 Jun 19. doi: 10.1038/s41467-020-16664-0

PMCID:: PMC7305236

Abstract Article PDF–1.7M

Select item 729373413.

CXCR7 Inhibits Fibrosis via Wnt/β-Catenin Pathways during the Process of Angiogenesis in Human Umbilical Vein Endothelial Cells

MinQian Shen, YiFan Feng, Jing Wang, YuanZhi Yuan, Fei Yuan

Biomed Res Int. 2020; 2020: 1216926. Published online 2020 Jun 5. doi: 10.1155/2020/1216926

PMCID:: PMC7293734

Abstract Article PDF–1.6M

Select item 719862514.

Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling

Sung-Tai Wei, Yen‐Chih Huang, Mei-Ling Hsieh, Yu-Jung Lin, Woei-Cherng Shyu, Hui-Chen Chen, Chia-Hung Hsieh

Cell Death Dis. 2020 May; 11(5): 307. Published online 2020 May 4. doi: 10.1038/s41419-020-2512-2

PMCID:: PMC7198625

Abstract Article PDF–4.1M

Select item 674617515.

CXCR7 reactivates ERK signaling to promote resistance to EGFR kinase inhibitors in NSCLC.

Jeffrey H. Becker, Yandi Gao, Margaret Soucheray, Ines Pulido, Eiki Kikuchi, María L. Rodríguez, Rutu Gandhi, Aranzazu Lafuente-Sanchis, Miguel Aupí, Javier Alcácer Fernández-Coronado, Paloma Martín-Martorell, Antonio Cremades, José M. Galbis-Caravajal, Javier Alcácer, Camilla L. Christensen, Patricia Simms, Ashley Hess, Hajime Asahina, Michael P. Kahle, Fatima Al-Shahrour, Jeffrey A. Borgia, Agustín Lahoz, Amelia Insa, Oscar Juan, Pasi A. Jänne, Kwok-Kin Wong, Julian Carretero, Takeshi Shimamura

Cancer Res. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Cancer Res. 2019 Sep 1; 79(17): 4439–4452. Published online 2019 Jul 4. doi: 10.1158/0008-5472.CAN-19-0024

PMCID:: PMC6746175

Abstract Article PDF–1.6M

Select item 652228116.

Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer

Shangze Li, Ka-wing Fong, Galina Gritsina, Ali Zhang, Jonathan C. Zhao, Jung Kim, Adam Sharp, Wei Yuan, Caterina Aversa, Ximing J. Yang, Peter S. Nelson, Felix Y. Feng, Arul Chinnaiyan, Johann S. de Bono, Colm Morrissey, Matthew B. Rettig, Jindan Yu

Cancer Res. Author manuscript; available in PMC 2020 May 15.

Published in final edited form as: Cancer Res. 2019 May 15; 79(10): 2580–2592. Published online 2019 Apr 5. doi: 10.1158/0008-5472.CAN-18-2812

Correction in:: Cancer Res. 2020 May 15; 80(10): 2072.

PMCID:: PMC6522281

Abstract Article PDF–2.5M

Select item 633040017.

LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway

Nan Li, Huanbai Xu, Yurong Ou, Zhenzhong Feng, Qiong Zhang, Qing Zhu, Zhaogen Cai

Diagn Pathol. 2019; 14: 3. Published online 2019 Jan 12. doi: 10.1186/s13000-019-0780-x

PMCID:: PMC6330400

Abstract Article PDF–3.4M

Select item 607406118.

Upregulation of CXCR7 Is Associated with Poor Prognosis of Prostate Cancer

Jihua Yang, Hao Tang, Jingyu Huang, Huaijie An

Med Sci Monit. 2018; 24: 5185–5191. Published online 2018 Jul 26. doi: 10.12659/MSM.906180

PMCID:: PMC6074061

Abstract Article PDF–321K

Select item 600790219.

CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis

María José Moreno, Alberto Gallardo, Silvana Novelli, Ana Mozos, Marc Aragó, Miguel Ángel Pavón, María Virtudes Céspedes, Víctor Pallarès, Aïda Falgàs, Miguel Alcoceba, Oscar Blanco, Marcos Gonzalez-Díaz, Jorge Sierra, Ramon Mangues, Isolda Casanova

PLoS One. 2018; 13(6): e0198789. Published online 2018 Jun 19. doi: 10.1371/journal.pone.0198789

PMCID:: PMC6007902

Abstract Article PDF–10M

Select item 598012720.

Critical involvement of atypical chemokine receptor CXCR7 in allergic airway inflammation

Hung‐Chih Chang, Po‐Han Huang, Fu‐Sheng Syu, Chia‐Hung Hsieh, Sunny Li‐Yun Chang, Jean Lu, Hui‐Chen Chen

Immunology. 2018 Jun; 154(2): 274–284. Published online 2018 Jan 12. doi: 10.1111/imm.12881

PMCID:: PMC5980127

Abstract Article PDF–868K

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