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Select item 109621181.

PELI1: key players in the oncogenic characteristics of pancreatic Cancer

Xiaobin Fei, Changhao Zhu, Peng Liu, Songbai Liu, Likun Ren, Rishang Lu, Junyi Hou, Yongjia Gao, Xing Wang, Yaozhen Pan

J Exp Clin Cancer Res. 2024; 43: 91. Published online 2024 Mar 25. doi: 10.1186/s13046-024-03008-9

PMCID:: PMC10962118

Abstract Article PDF–15M

Select item 89365152.

PELI1 promotes radiotherapy sensitivity by inhibiting noncanonical NF‐κB in esophageal squamous cancer

Dongfang Dai, Hongping Zhou, Li Yin, Fei Ye, Xiao Yuan, Tao You, Xiaohui Zhao, Weiguo Long, Deqiang Wang, Xia He, Jifeng Feng, Deyu Chen

Mol Oncol. 2022 Mar; 16(6): 1384–1401. Published online 2021 Nov 14. doi: 10.1002/1878-0261.13134

PMCID:: PMC8936515

Abstract Article PDF–3.9M

Select item 54576853.

Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination

Yoon Kyung Jeon, Chung Kwon Kim, Kyung Rim Hwang, Hye-Young Park, Jaemoon Koh, Doo Hyun Chung, Chang-Woo Lee, Geun-Hyoung Ha

Cell Death Differ. 2017 Mar; 24(3): 469–480. Published online 2016 Dec 23. doi: 10.1038/cdd.2016.143

PMCID:: PMC5457685

Abstract Article PDF–4.8M

Select item 99683144.

PELI1 and EGFR cooperate to promote breast cancer metastasis

Jie Qi, Guangsen Xu, Xiaoxia Wu, Chunhua Lu, Yuemao Shen, Baobing Zhao

Oncogenesis. 2023 Dec; 12(1): 9. Published online 2023 Feb 25. doi: 10.1038/s41389-023-00457-3

PMCID:: PMC9968314

Abstract Article PDF–5.2M

Select item 73917655.

Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation

Shan-shan Liu, Jie Qi, Zu-dong Teng, Fu-tao Tian, Xiao-xi Lv, Ke Li, Ya-jie Song, Wei-dong Xie, Zhuo-wei Hu, Xia Li

Signal Transduct Target Ther. 2020; 5: 133. Published online 2020 Jul 29. doi: 10.1038/s41392-020-00255-y

PMCID:: PMC7391765

Article PDF–1.2M

Select item 71749296.

miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency

Xinran Li, Jiaxin Xie, Qingru Wang, Huihua Cai, Chuhai Xie, Xiafei Fu

J Immunol Res. 2020; 2020: 3582648. Published online 2020 Apr 13. doi: 10.1155/2020/3582648

PMCID:: PMC7174929

Abstract Article PDF–1.1M

Select item 65416527.

Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation

Dongfang Dai, Jia Yuan, Yan Wang, Jing Xu, Chaoming Mao, Yichuan Xiao

Sci Rep. 2019; 9: 8034. Published online 2019 May 29. doi: 10.1038/s41598-019-44573-w

PMCID:: PMC6541652

Abstract Article PDF–3.3M

Select item 56926058.

PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP

Huibing Wang, Huyan Meng, Xingyan Li, Kezhou Zhu, Kangyun Dong, Adnan K. Mookhtiar, Huiting Wei, Ying Li, Shao-Cong Sun, Junying Yuan

Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11944–11949. Published online 2017 Oct 23. doi: 10.1073/pnas.1715742114

PMCID:: PMC5692605

Abstract Article PDF–1.0M

Select item 51730989.

Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination

Yoon Kyung Jeon, Chung Kwon Kim, Jaemoon Koh, Doo Hyun Chung, Geun-Hyoung Ha

Oncotarget. 2016 Jul 5; 7(27): 41811–41824. Published online 2016 May 26. doi: 10.18632/oncotarget.9619

PMCID:: PMC5173098

Abstract Article PDF–13M

Select item 874046810.

MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma

Tingting Zheng, Youxing Zhou, Xiaowei Xu, Xin Qi, Jiameng Liu, Yanan Pu, Shan Zhang, Xuerong Gao, Xinkai Luo, Mei Li, Xuefeng Wang, Liyang Dong, Ying Wang, Chaoming Mao

J Transl Med. 2022; 20: 20. Published online 2022 Jan 6. doi: 10.1186/s12967-021-03226-1

PMCID:: PMC8740468

Abstract Article PDF–7.5M

Select item 868452011.

MiR-301a-3p Advances IRAK1-Mediated Differentiation of Th17 Cells to Promote the Progression of Systemic Lupus Erythematosus via Targeting PELI1

Shuaihantian Luo, Ruifang Wu, Qianwen Li, Guiying Zhang

J Healthc Eng. 2021; 2021: 2982924. Published online 2021 Dec 11. doi: 10.1155/2021/2982924

PMCID:: PMC8684520

Abstract Article PDF–550K

Select item 729731012.

Peli1 signaling blockade attenuates congenital zika syndrome

Huanle Luo, Guangyu Li, Binbin Wang, Bing Tian, Junling Gao, Jing Zou, Shuizhen Shi, Shuang Zhu, Bi-Hung Peng, Awadalkareem Adam, Ariza Martinez, Kimberly Hein, Evandro R. Winkelmann, Yoseph Mahmoud, Xiaofei Zhou, Chao Shan, Shannan Rossi, Scott Weaver, Alan D. T. Barrett, Shao-Cong Sun, Wenbo Zhang, Pei-Yong Shi, Ping Wu, Tian Wang

PLoS Pathog. 2020 Jun; 16(6): e1008538. Published online 2020 Jun 16. doi: 10.1371/journal.ppat.1008538

PMCID:: PMC7297310

Abstract Article PDF–2.8M

Select item 434722713.

Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination

Hye-Young Park, Heounjeong Go, Ha Rim Song, Suhyeon Kim, Geun-Hyoung Ha, Yoon-Kyung Jeon, Ji-Eun Kim, Ho Lee, Hyeseong Cho, Ho Chul Kang, Hee-Young Chung, Chul-Woo Kim, Doo Hyun Chung, Chang-Woo Lee

J Clin Invest. 2014 Nov 3; 124(11): 4976–4988. Published online 2014 Oct 8. doi: 10.1172/JCI75667

PMCID:: PMC4347227

Abstract Article PDF–2.5M

Select item 420515814.

Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1

Chun-Chi Lin, Yu-San Huoh, Karl R. Schmitz, Liselotte E. Jensen, Kathryn M. Ferguson

Structure. Author manuscript; available in PMC 2014 Oct 21.

Published in final edited form as: Structure. 2008 Dec 10; 16(12): 1806–1816. doi: 10.1016/j.str.2008.09.011

PMCID:: PMC4205158

Abstract Article PDF–1.6M

Select item 390686815.

Pellino-1, an Adaptor Protein of Interleukin-1 Receptor/Toll-like Receptor Signaling, Is Sumoylated by Ubc9

Jun Hwan Kim, Ki Sa Sung, Su Myung Jung, Youn Sook Lee, Jae Young Kwon, Cheol Yong Choi, Seok Hee Park

Mol Cells. 2011 Jan 31; 31(1): 85–89. doi: 10.1007/s10059-011-0006-x

PMCID:: PMC3906868

Abstract Article PDF–432K

Select item 892459516.

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1

Lin Shang, Tao Peng, Xuemei Chen, Zhiyong Yan, Junmin Wang, Xiaoqun Gao, Cheng Chang

Anal Cell Pathol (Amst) 2022; 2022: 7657995. Published online 2022 Mar 8. doi: 10.1155/2022/7657995

PMCID:: PMC8924595

Abstract Article PDF–3.5M

Select item 780970217.

The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses

Chun‐Jung Ko, Lingyun Zhang, Zuliang Jie, Lele Zhu, Xiaofei Zhou, Xiaoping Xie, Tianxiao Gao, Jin‐Young Yang, Xuhong Cheng, Shao‐Cong Sun

EMBO J. 2021 Jan 15; 40(2): e104532. Published online 2020 Nov 20. doi: 10.15252/embj.2020104532

PMCID:: PMC7809702

Abstract Article PDF–1.9M

Select item 593086418.

Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation

Sinéad Kinsella, Michael Fichtner, Orla Watters, Hans-Georg König, Jochen H. M. Prehn

J Neuroinflammation. 2018; 15: 130. Published online 2018 May 2. doi: 10.1186/s12974-018-1143-3

PMCID:: PMC5930864

Abstract Article PDF–2.0M

Select item 585915019.

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus

Junli Liu, Xinfang Huang, Shumeng Hao, Yan Wang, Manman Liu, Jing Xu, Xingli Zhang, Tao Yu, Shucheng Gan, Dongfang Dai, Xuan Luo, Qingyan Lu, Chaoming Mao, Yanyun Zhang, Nan Shen, Bin Li, Mingzhu Huang, Xiaodong Zhu, Jin Jin, Xuhong Cheng, Shao-Cong Sun, Yichuan Xiao

Nat Commun. 2018; 9: 1136. Published online 2018 Mar 19. doi: 10.1038/s41467-018-03530-3