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Select item 105527381.

USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitination-mediated degradation

Tao Lv, Bo Zhang, Chenghao Jiang, Qiwen Zeng, Jiayin Yang, Yongjie Zhou

Int J Oncol. 2023 Oct; 63(4): 113. Published online 2023 Aug 14. doi: 10.3892/ijo.2023.5561

PMCID:: PMC10552738

Abstract Article PDF–3.7M

Select item 103078602.

The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma

Shanshan Wang, Taishu Wang, Xuehong Zhang, Shaoxuan Cheng, Chaoqun Chen, Guoheng Yang, Fuqiang Wang, Ruilin Wang, Qingqing Zhang, Dian Yang, Yingqiu Zhang, Shuyan Liu, Hongqiang Qin, Quentin Liu, Han Liu

Cell Death Differ. 2023 Jul; 30(7): 1757–1770. Published online 2023 May 12. doi: 10.1038/s41418-023-01176-3

PMCID:: PMC10307860

Abstract Article PDF–9.9M

Select item 80879313.

Deubiquitinase USP35 modulates ferroptosis in lung cancer via targeting ferroportin

Zheng Tang, Wanli Jiang, Ming Mao, Jinping Zhao, Jiakuan Chen, Nitao Cheng

Clin Transl Med. 2021 Apr; 11(4): e390. Published online 2021 May 1. doi: 10.1002/ctm2.390

PMCID:: PMC8087931

Abstract Article PDF–6.3M

Select item 60313304.

Expansion of DUB functionality generated by alternative isoforms – USP35, a case study

Pawel Leznicki, Jayaprakash Natarajan, Gerd Bader, Walter Spevak, Andreas Schlattl, Syed Arif Abdul Rehman, Deepika Pathak, Simone Weidlich, Andreas Zoephel, Marie C. Bordone, Nuno L. Barbosa-Morais, Guido Boehmelt, Yogesh Kulathu

J Cell Sci. 2018 May 15; 131(10): jcs212753. Published online 2018 May 16. doi: 10.1242/jcs.212753

PMCID:: PMC6031330

Abstract Article

Select item 107976865.

Ubiquitin-specific Protease 35 Promotes Gastric Cancer Metastasis by Increasing the Stability of Snail1

Cunying Ma, Zhuangfei Tian, Dandan Wang, Wenrong Gao, Lilin Qian, Yichen Zang, Xia Xu, Jihui Jia, Zhifang Liu

Int J Biol Sci. 2024; 20(3): 953–967. Published online 2024 Jan 12. doi: 10.7150/ijbs.87176

PMCID:: PMC10797686

Abstract Article PDF–5.1M

Select item 89785136.

USP35 mitigates endoplasmic reticulum stress‐induced apoptosis by stabilizing RRBP1 in non‐small cell lung cancer

Wenqing Wang, Meixia Wang, Yi Xiao, Yige Wang, Lijuan Ma, Lulu Guo, Xinyue Wu, Xiaoyan Lin, Pengju Zhang

Mol Oncol. 2022 Apr; 16(7): 1572–1590. Published online 2021 Oct 18. doi: 10.1002/1878-0261.13112

PMCID:: PMC8978513

Abstract Article PDF–3.9M

Select item 82061207.

USP35, regulated by estrogen and AKT, promotes breast tumorigenesis by stabilizing and enhancing transcriptional activity of estrogen receptor α

Jiawei Cao, Du Wu, Guang Wu, Yaqi Wang, Tianhao Ren, Yang Wang, Yingshuai Lv, Wei Sun, Jieyi Wang, Changrui Qian, Licai He, Kaiyan Yang, Hongzhi Li, Haihua Gu

Cell Death Dis. 2021 Jun; 12(6): 619. Published online 2021 Jun 15. doi: 10.1038/s41419-021-03904-4

PMCID:: PMC8206120

Abstract Article PDF–3.0M

Select item 58144538.

USP35 regulates mitotic progression by modulating the stability of Aurora B

Jinyoung Park, Mi-Sun Kwon, Eunice EunKyeong Kim, Hyunsook Lee, Eun Joo Song

Nat Commun. 2018; 9: 688. Published online 2018 Feb 15. doi: 10.1038/s41467-018-03107-0

PMCID:: PMC5814453

Abstract Article PDF–2.2M

Select item 110733049.

USP35 dimer prevents its degradation by E3 ligase CHIP through auto-deubiquitinating activity

Jinyoung Park, Sang Chul Shin, Kyeong Sik Jin, Min Joon Lim, Yeojin Kim, Eunice EunKyeong Kim, Eun Joo Song

Cell Mol Life Sci. 2023 Apr; 80(4): 112. Published online 2023 Apr 1. doi: 10.1007/s00018-023-04740-9

PMCID:: PMC11073304

Abstract Article PDF–4.6M

Select item 450282310.

Deubiquitinating enzymes regulate PARK2-mediated mitophagy

Yuqing Wang, Mauro Serricchio, Miluska Jauregui, Riya Shanbhag, Tasha Stoltz, Caitlin T Di Paolo, Peter K Kim, G Angus McQuibban

Autophagy. 2015 Apr; 11(4): 595–606. Published online 2015 Apr 27. doi: 10.1080/15548627.2015.1034408

PMCID:: PMC4502823

Abstract Article PDF–1.0M

Select item 469503311.

USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2

Chunyan Liu, Lina Wang, Weiwen Chen, Shihu Zhao, Chunli Yin, Yani Lin, Anli Jiang, Pengju Zhang

Oncotarget. 2015 Sep 29; 6(29): 27891–27906. Published online 2015 Jun 26. doi: 10.18632/oncotarget.4451

PMCID:: PMC4695033

Abstract Article PDF–6.2M

Select item 785313912.

Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer

Jiawen Zhang, Yunfei Chen, Xianfei Chen, Wen Zhang, Linlin Zhao, Linjun Weng, Hongling Tian, Zhiqiang Wu, Xiao Tan, Xin Ge, Ping Wang, Lan Fang

Cell Death Differ. 2021 Jan; 28(1): 139–155. Published online 2020 Jul 16. doi: 10.1038/s41418-020-0588-y

PMCID:: PMC7853139

Abstract Article PDF–5.8M

Select item 964970313.

Deubiquitinase USP35 stabilizes BRPF1 to activate mevalonate (MVA) metabolism during prostate tumorigenesis

Guowen Lin, Tianrun Huang, Xiaobo Zhang, Gangmin Wang

Cell Death Discov. 2022; 8: 453. Published online 2022 Nov 10. doi: 10.1038/s41420-022-01231-x

PMCID:: PMC9649703

Abstract Article PDF–6.3M

Select item 998158314.

USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer

Yi Xiao, Xiaoyu Jiang, Ke Yin, Tianshu Miao, Hanlin Lu, Wenqing Wang, Lijuan Ma, Yinghui Zhao, Chunyan Liu, Yun Qiao, Pengju Zhang

Oncogenesis. 2023 Dec; 12(1): 12. Published online 2023 Mar 3. doi: 10.1038/s41389-023-00458-2

PMCID:: PMC9981583

Abstract Article PDF–3.9M

Select item 1016374515.

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging

Yinan Li, Xiu Huang, Jing Jin, Haohao Zhang, Kai Yang, Jingxia Han, Ying Lv, Yu Sun, Cheng Yao, Tingting Lin, Caibin Zhu, Huijuan Liu

Cell Biosci. 2023; 13: 80. Published online 2023 May 6. doi: 10.1186/s13578-023-01029-z

PMCID:: PMC10163745

Abstract Article PDF–11M

Select item 694886116.

Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies

I-Chun Tsai, Kevin A. Adams, Joyce A. Tzeng, Omar Shennib, Perciliz L. Tan, Nicholas Katsanis

JCI Insight. 2019 Nov 14; 4(22): e130516. Published online 2019 Nov 14. doi: 10.1172/jci.insight.130516

PMCID:: PMC6948861

Abstract Article PDF–5.1M

Select item 514341417.

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA

Man Zhang, Meng-Xin Zhang, Qiang Zhang, Gao-Feng Zhu, Lei Yuan, Dong-Er Zhang, Qiyun Zhu, Jing Yao, Hong-Bing Shu, Bo Zhong

Cell Res. 2016 Dec; 26(12): 1302–1319. Published online 2016 Nov 1. doi: 10.1038/cr.2016.125

PMCID:: PMC5143414

Abstract Article PDF–5.5M

Select item 631827318.

Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

Tianzi Liuyu, Keying Yu, Liya Ye, Zhidong Zhang, Man Zhang, Yujie Ren, Zeng Cai, Qiyun Zhu, Dandan Lin, Bo Zhong

Cell Res. 2019 Jan; 29(1): 67–79. Published online 2018 Nov 8. doi: 10.1038/s41422-018-0107-6

PMCID:: PMC6318273

Abstract Article PDF–2.9M

Select item 621963319.

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas

Christopher G. Abraham, Michael P. Ludwig, Zdenek Andrysik, Ahwan Pandey, Molishree Joshi, Matthew D. Galbraith, Kelly D. Sullivan, Joaquin M. Espinosa

Cell Rep. Author manuscript; available in PMC 2018 Nov 6.

Published in final edited form as: Cell Rep. 2018 Sep 18; 24(12): 3224–3236. doi: 10.1016/j.celrep.2018.08.058

PMCID:: PMC6219633

Abstract Article PDF–1.1M

Select item 589620220.

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Dominika Kwasna, Syed Arif Abdul Rehman, Jayaprakash Natarajan, Stephen Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs-Seymour, Yogesh Kulathu

Mol Cell. 2018 Apr 5; 70(1): 150–164.e6. doi: 10.1016/j.molcel.2018.02.023