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Select item 110124861.

Identification of PTPN12 Phosphatase as a Novel Negative Regulator of Hippo Pathway Effectors YAP/TAZ in Breast Cancer

Sahar Sarmasti Emami, Anni Ge, Derek Zhang, Yawei Hao, Min Ling, Rachel Rubino, Christopher J. B. Nicol, Wenqi Wang, Xiaolong Yang

Int J Mol Sci. 2024 Apr; 25(7): 4064. Published online 2024 Apr 5. doi: 10.3390/ijms25074064

PMCID:: PMC11012486

Abstract Article PDF–6.7M

Select item 77317202.

Expression and clinical significance of PTPN12 in clear cell renal cell carcinoma

Yi Jin, Tian-xi Wang, Hao Li, Peng Guo, Qing-qing Wang

J Int Med Res. 2020 Dec; 48(12): 0300060520936041. Published online 2020 Dec 8. doi: 10.1177/0300060520936041

PMCID:: PMC7731720

Abstract Article PDF–866K

Select item 73026173.

Progress in the correlation between PTPN12 gene expression and human tumors

Yu-hu Huo, Ya-ni Wang, Ling-bing Meng, Ai-li Zhang, Bin Liu

Medicine (Baltimore) 2020 Jun 12; 99(24): e20445. Published online 2020 Jun 12. doi: 10.1097/MD.0000000000020445

PMCID:: PMC7302617

Abstract Article PDF–201K

Select item 67900474.

High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

Sören A. Weidemann, Charlotte Sauer, Andreas M. Luebke, Christina Möller-Koop, Stefan Steurer, Claudia Hube-Magg, Franziska Büscheck, Doris Höflmayer, Maria Christina Tsourlakis, Till S. Clauditz, Ronald Simon, Guido Sauter, Cosima Göbel, Patrick Lebok, David Dum, Christoph Fraune, Simon Kind, Sarah Minner, Jakob Izbicki, Thorsten Schlomm, Hartwig Huland, Hans Heinzer, Eike Burandt, Alexander Haese, Markus Graefen, Asmus Heumann

BMC Cancer. 2019; 19: 944. Published online 2019 Oct 12. doi: 10.1186/s12885-019-6182-3

PMCID:: PMC6790047

Abstract Article PDF–1.7M

Select item 60501345.

PTPN12/PTP-PEST Regulates Phosphorylation-Dependent Ubiquitination and Stability of Focal Adhesion Substrates in Invasive Glioblastoma Cells

Zhihua Chen, John E. Morales, Paola A. Guerrero, Huandong Sun, Joseph H. McCarty

Cancer Res. Author manuscript; available in PMC 2019 Jul 15.

Published in final edited form as: Cancer Res. 2018 Jul 15; 78(14): 3809–3822. Published online 2018 May 9. doi: 10.1158/0008-5472.CAN-18-0085

PMCID:: PMC6050134

Abstract Article PDF–1.2M

Select item 57960106.

Structure and Molecular Dynamics Simulations of Protein Tyrosine Phosphatase Non-Receptor 12 Provide Insights into the Catalytic Mechanism of the Enzyme

Hui Dong, Francesco Zonta, Shanshan Wang, Ke Song, Xin He, Miaomiao He, Yan Nie, Sheng Li

Int J Mol Sci. 2018 Jan; 19(1): 60. Published online 2017 Dec 26. doi: 10.3390/ijms19010060

PMCID:: PMC5796010

Abstract Article PDF–2.6M

Select item 49448967.

Hepatitis B virus mutations, expression quantitative trait loci for PTPN12, and their interactions in hepatocellular carcinoma

Ci Song, Yao Liu, Lu Xu, Juan Wen, Deke Jiang, Jianguo Chen, Xiangjun Zhai, Zhibin Hu, Li Liu, Jibin Liu

Cancer Med. 2016 Jul; 5(7): 1687–1693. Published online 2016 Apr 14. doi: 10.1002/cam4.712

PMCID:: PMC4944896

Abstract Article PDF–110K

Select item 45169028.

The prognostic significance of tyrosine-protein phosphatase nonreceptor type 12 expression in nasopharyngeal carcinoma

Xin-Ke Zhang, Miao Xu, Jie-Wei Chen, Feng Zhou, Yi-Hong Ling, Chong-Mei Zhu, Jing-Ping Yun, Mu-Yan Cai, Rong-Zhen Luo

Tumour Biol. 2015 Jul; 36(7): 5201–5208. Published online 2015 Feb 9. doi: 10.1007/s13277-015-3176-x

PMCID:: PMC4516902

Abstract Article PDF–1.0M

Select item 44844889.

Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer

Xun Cao, Yan-Zhen Chen, Ruo-Zhen Luo, Lin Zhang, Song-Liang Zhang, Jun Zeng, Yu-Chuan Jiang, Yu-Jing Han, Zhe-Sheng Wen

Oncotarget. 2015 May 10; 6(13): 11704–11713. Published online 2015 Mar 14. doi: 10.18632/oncotarget.3588

PMCID:: PMC4484488

Abstract Article PDF–3.0M

Select item 390165510.

Decreased Expression of PTPN12 Correlates with Tumor Recurrence and Poor Survival of Patients with Hepatocellular Carcinoma

Rong-Zhen Luo, Pei-Qiang Cai, Mei Li, Jia Fu, Zhi-Yi Zhang, Jie-Wei Chen, Yun Cao, Jing-Ping Yun, Dan Xie, Mu-Yan Cai

PLoS One. 2014; 9(1): e85592. Published online 2014 Jan 24. doi: 10.1371/journal.pone.0085592

PMCID:: PMC3901655

Abstract Article PDF–793K

Select item 385421311.

Clinicopathological significance of PTPN12 expression in human breast cancer

Xunyi Yuan, Zhentao Yuan, Dandan Jiang, Funian Li

Braz J Med Biol Res. 2012 Dec; 45(12): 1334–1340. Published online 2012 Oct 15. doi: 10.1590/S0100-879X2012007500163

PMCID:: PMC3854213

Abstract Article PDF–2.4M

Select item 292863212.

PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells

Rosario Espejo, William Rengifo-Cam, Michael D. Schaller, B. Mark Evers, Sarita K. Sastry

Am J Physiol Cell Physiol. 2010 Aug; 299(2): C454–C463. Published online 2010 Jun 2. doi: 10.1152/ajpcell.00148.2010

PMCID:: PMC2928632

Abstract Article

Select item 651878213.

Clinical implications of a novel prognostic factor AIFM3 in breast cancer patients

Ang Zheng, Lin Zhang, Xinyue Song, Yuying Wang, Minjie Wei, Feng Jin

BMC Cancer. 2019; 19: 451. Published online 2019 May 14. doi: 10.1186/s12885-019-5659-4

PMCID:: PMC6518782

Abstract Article PDF–5.5M

Select item 627951214.

Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma

Yang Xu, Paul Taylor, Joshua Andrade, Beatrix Ueberheide, Brian Shuch, Peter M. Glazer, Ranjit S. Bindra, Michael F. Moran, W. Marston Linehan, Benjamin G. Neel

Cancer Res. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Cancer Res. 2018 Dec 1; 78(23): 6539–6548. Published online 2018 Oct 8. doi: 10.1158/0008-5472.CAN-18-0901

PMCID:: PMC6279512

Abstract Article PDF–1.9M

Select item 400776215.

PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity

Rosario Espejo, Yowjiun Jeng, Adriana Paulucci-Holthauzen, William Rengifo-Cam, Krysta Honkus, Panos Z. Anastasiadis, Sarita K. Sastry

J Cell Sci. 2014 Feb 1; 127(3): 497–508. doi: 10.1242/jcs.120154

PMCID:: PMC4007762

Abstract Article

Select item 23164216.

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

A J Garton, A J Flint, N K Tonks

Mol Cell Biol. 1996 Nov; 16(11): 6408–6418. doi: 10.1128/mcb.16.11.6408

PMCID:: PMC231642

Summary PDF–2.2M

Select item 12551317.

PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates

Dominique Davidson, André Veillette

EMBO J. 2001 Jul 2; 20(13): 3414–3426. doi: 10.1093/emboj/20.13.3414

PMCID:: PMC125513

Abstract Article PDF–413K

Select item 884093018.

PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders

José A. Manso, Tamara Marcos, Virginia Ruiz-Martín, Javier Casas, Pablo Alcón, Mariano Sánchez Crespo, Yolanda Bayón, José M. de Pereda, Andrés Alonso

Cell Mol Life Sci. 2022 Feb; 79(2): 131. Published online 2022 Feb 12. doi: 10.1007/s00018-022-04173-w

PMCID:: PMC8840930

Abstract Article PDF–2.2M

Select item 320933319.

Ras-Induced and Extracellular Signal-Regulated Kinase 1 and 2 Phosphorylation-Dependent Isomerization of Protein Tyrosine Phosphatase (PTP)-PEST by PIN1 Promotes FAK Dephosphorylation by PTP-PEST

Yanhua Zheng, Weiwei Yang, Yan Xia, David Hawke, David X. Liu, Zhimin Lu

Mol Cell Biol. 2011 Nov; 31(21): 4258–4269. doi: 10.1128/MCB.05547-11

PMCID:: PMC3209333

Abstract Article PDF–2.7M

Select item 117107820.

A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.

J Li, K Nishizawa, W An, R E Hussey, F E Lialios, R Salgia, R Sunder-Plassmann, E L Reinherz

EMBO J. 1998 Dec 15; 17(24): 7320–7336. doi: 10.1093/emboj/17.24.7320

PMCID:: PMC1171078

Summary PDF–668K

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