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Select item 42846521.

Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation

Fränze Progatzky, Navjyot J. Sangha, Nagisa Yoshida, Marie McBrien, Jackie Cheung, Alice Shia, James Scott, Julian R. Marchesi, Jonathan R. Lamb, Laurence Bugeon, Margaret J. Dallman

Nat Commun. 2014 Dec 23; 5: 5864. Published online 2014 Dec 23. doi: 10.1038/ncomms6864

PMCID:: PMC4284652

Abstract Article PDF–1.7M

Select item 65896772.

Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner

Ali Sepahi, Aurora Kraus, Elisa Casadei, Christopher A. Johnston, Jorge Galindo-Villegas, Cecelia Kelly, Diana García-Moreno, Pilar Muñoz, Victoriano Mulero, Mar Huertas, Irene Salinas

Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12428–12436. Published online 2019 Jun 3. doi: 10.1073/pnas.1900083116

PMCID:: PMC6589677

Abstract Article PDF–1.9M

Select item 83890073.

Fisetin Inhibits NLRP3 Inflammasome by Suppressing TLR4/MD2-Mediated Mitochondrial ROS Production

Ilandarage Menu Neelaka Molagoda, Athapaththu Mudiyanselage Gihan Kavinda Athapaththu, Yung Hyun Choi, Cheol Park, Cheng-Yung Jin, Chang-Hee Kang, Mi-Hwa Lee, Gi-Young Kim

Antioxidants (Basel) 2021 Aug; 10(8): 1215. Published online 2021 Jul 28. doi: 10.3390/antiox10081215

PMCID:: PMC8389007

Abstract Article PDF–6.6M

Select item 63511024.

Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection

Molly A Matty, Daphne R Knudsen, Eric M Walton, Rebecca W Beerman, Mark R Cronan, Charlie J Pyle, Rafael E Hernandez, David M Tobin

eLife. 2019; 8: e39123. Published online 2019 Jan 29. doi: 10.7554/eLife.39123

PMCID:: PMC6351102

Abstract Article PDF–4.7M

Select item 61053675.

Functional and structural characterization of zebrafish ASC

Yajuan Li, Yi Huang, Xiaocong Cao, Xueying Yin, Xiangyu Jin, Sheng Liu, Jiansheng Jiang, Wei Jiang, Tsan Sam Xiao, Rongbin Zhou, Gang Cai, Bing Hu, Tengchuan Jin

FEBS J. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: FEBS J. 2018 Jul; 285(14): 2691–2707. Published online 2018 Jun 14. doi: 10.1111/febs.14514

PMCID:: PMC6105367

Abstract Article PDF–2.5M

Select item 60826436.

Tissue damage signaling is a prerequisite for protective neutrophil recruitment to microbial infection in zebrafish

Cong Huang, Philipp Niethammer

Immunity. Author manuscript; available in PMC 2019 May 15.

Published in final edited form as: Immunity. 2018 May 15; 48(5): 1006–1013.e6. doi: 10.1016/j.immuni.2018.04.020

PMCID:: PMC6082643

Abstract Article PDF–2.1M

Select item 56628747.

Identification of an Evolutionarily Conserved Ankyrin Domain-Containing Protein, Caiap, Which Regulates Inflammasome-Dependent Resistance to Bacterial Infection

Sylwia D. Tyrkalska, Sergio Candel, Ana B. Pérez-Oliva, Ana Valera, Francisca Alcaraz-Pérez, Diana García-Moreno, María L. Cayuela, Victoriano Mulero

Front Immunol. 2017; 8: 1375. Published online 2017 Oct 19. doi: 10.3389/fimmu.2017.01375

PMCID:: PMC5662874

Abstract Article PDF–7.1M

Select item 37291588.

Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein

Tengchuan Jin, Mo Huang, Patrick Smith, Jiansheng Jiang, T. Sam Xiao

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug 1; 69(Pt 8): 855–860. Published online 2013 Jul 27. doi: 10.1107/S1744309113015558

PMCID:: PMC3729158

Abstract Article PDF–1.0M

Select item 55841809.

Dynamics of in vivo ASC speck formation

Paola Kuri, Nicole L. Schieber, Thomas Thumberger, Joachim Wittbrodt, Yannick Schwab, Maria Leptin

J Cell Biol. 2017 Sep 4; 216(9): 2891–2909. doi: 10.1083/jcb.201703103

Correction in:: J Cell Biol. 2017 Oct 2; 216(10): 3423–3424.

PMCID:: PMC5584180

Abstract Article PDF–3.7M

Select item 591278010.

Chromatin accessibility is associated with CRISPR-Cas9 efficiency in the zebrafish (Danio rerio)

Meri I. E. Uusi-Mäkelä, Harlan R. Barker, Carina A. Bäuerlein, Tomi Häkkinen, Matti Nykter, Mika Rämet

PLoS One. 2018; 13(4): e0196238. Published online 2018 Apr 23. doi: 10.1371/journal.pone.0196238

PMCID:: PMC5912780

Abstract Article PDF–3.0M

Select item 917446011.

Negative Regulator Nlrc3-like Maintain the Balanced Innate Immune Response During Mycobacterial Infection in Zebrafish

Liangfei Niu, Geyang Luo, Rui Liang, Chenli Qiu, Jianwei Yang, Lingling Xie, Kaile Zhang, Yu Tian, Decheng Wang, Shu Song, Howard E. Takiff, Ka-Wing Wong, Xiaoyong Fan, Qian Gao, Bo Yan

Front Immunol. 2022; 13: 893611. Published online 2022 May 25. doi: 10.3389/fimmu.2022.893611

PMCID:: PMC9174460

Abstract Article PDF–9.0M

Select item 984421312.

DPP9 deficiency: an Inflammasomopathy which can be rescued by lowering NLRP1/IL-1 signaling

Cassandra R. Harapas, Kim S. Robinson, Kenneth Lay, Jasmine Wong, Ricardo Moreno Traspas, Nasrin Nabavizadeh, Annick Rass-Rothschild, Bertrand Boisson, Scott B. Drutman, Pawat Laohamonthonkul, Devon Bonner, Jingwei Rachel Xiong, Mark D. Gorrell, Sophia Davidson, Chien-Hsiung Yu, Mark D. Fleming, Jonas Gudera, Jerry Stein, Miriam Ben-Harosh, Emily Groopman, Akiko Shimamura, Hannah Tamary, Hülya Kayserili, Nevin Hatipoğlu, Jean-Laurent Casanova, Jonathan A. Bernstein, Franklin L. Zhong, Seth L. Masters, Bruno Reversade

Sci Immunol. Author manuscript; available in PMC 2023 Mar 16.

Published in final edited form as: Sci Immunol. 2022 Sep 16; 7(75): eabi4611. Published online 2022 Sep 16. doi: 10.1126/sciimmunol.abi4611

PMCID:: PMC9844213

Abstract Article PDF–1.7M

Select item 688636413.

Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1

Sylwia D. Tyrkalska, Ana B. Pérez-Oliva, Lola Rodríguez-Ruiz, Francisco J. Martínez-Morcillo, Francisca Alcaraz-Pérez, Francisco J. Martínez-Navarro, Christophe Lachaud, Nouraiz Ahmed, Timm Schroeder, Irene Pardo-Sánchez, Sergio Candel, Azucena López-Muñoz, Avik Choudhuri, Marlies P. Rossmann, Leonard I. Zon, María L. Cayuela, Diana García-Moreno, Victoriano Mulero

Immunity. Author manuscript; available in PMC 2019 Dec 2.

Published in final edited form as: Immunity. 2019 Jul 16; 51(1): 50–63.e5. Published online 2019 Jun 4. doi: 10.1016/j.immuni.2019.05.005

PMCID:: PMC6886364

Abstract Article PDF–2.5M

Select item 814964414.

Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease

Hideaki Matsui, Junko Ito, Noriko Matsui, Tamayo Uechi, Osamu Onodera, Akiyoshi Kakita

Nat Commun. 2021; 12: 3101. Published online 2021 May 25. doi: 10.1038/s41467-021-23452-x

PMCID:: PMC8149644

Abstract Article PDF–8.1M

Select item 997339915.

Oxoeicosanoid signaling mediates early antimicrobial defense in zebrafish

Yanan Ma, King Lam Hui, Zaza Gelashvili, Philipp Niethammer

Cell Rep. Author manuscript; available in PMC 2023 Feb 28.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111974. Published online 2023 Jan 10. doi: 10.1016/j.celrep.2022.111974

PMCID:: PMC9973399

Abstract Article PDF–1.9M

Select item 1056245816.

Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

Alexander Ernst, Indre Piragyte, Ayisha Marwa MP, Ngoc Dung Le, Denis Grandgirard, Stephen L. Leib, Andrew Oates, Nadia Mercader

Sci Rep. 2023; 13: 17037. Published online 2023 Oct 9. doi: 10.1038/s41598-023-43911-3

PMCID:: PMC10562458

Abstract Article PDF–12M

Select item 493218717.

Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins

Sylwia D. Tyrkalska, Sergio Candel, Diego Angosto, Victoria Gómez-Abellán, Fátima Martín-Sánchez, Diana García-Moreno, Rubén Zapata-Pérez, Álvaro Sánchez-Ferrer, María P. Sepulcre, Pablo Pelegrín, Victoriano Mulero

Nat Commun. 2016; 7: 12077. Published online 2016 Jul 1. doi: 10.1038/ncomms12077

PMCID:: PMC4932187

Abstract Article PDF–3.2M

Select item 948114018.

Differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern

Sylwia D. Tyrkalska, Alicia Martínez-López, Ana B. Arroyo, Francisco J. Martínez-Morcillo, Sergio Candel, Diana García-Moreno, Pablo Mesa-del-Castillo, María L. Cayuela, Victoriano Mulero

Sci Adv. 2022 Sep; 8(37): eabo0732. Published online 2022 Sep 16. doi: 10.1126/sciadv.abo0732

Correction in:: Sci Adv. 2022 Dec; 8(51): eadf9695.

PMCID:: PMC9481140

Abstract Article PDF–3.4M

Select item 698384519.

The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E–mediated pyroptosis

Jiang-Yuan Li, Yue-Yi Wang, Tong Shao, Dong-Dong Fan, Ai-Fu Lin, Li-Xin Xiang, Jian-Zhong Shao

J Biol Chem. 2020 Jan 24; 295(4): 1120–1141. Published online 2019 Dec 18. doi: 10.1074/jbc.RA119.011751

PMCID:: PMC6983845

Abstract Article PDF–8.3M

Select item 387865520.

An anti-inflammatory NOD-like receptor is required for microglia development

Celia E. Shiau, Kelly R. Monk, William Joo, William S. Talbot

Cell Rep. Author manuscript; available in PMC 2014 Dec 12.

Published in final edited form as: Cell Rep. 2013 Dec 12; 5(5): 10.1016/j.celrep.2013.11.004. Published online 2013 Dec 5. doi: 10.1016/j.celrep.2013.11.004

PMCID:: PMC3878655

Abstract Article PDF–2.5M

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