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Select item 112084461.

PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer’s disease

Alexandre Poirier, Cynthia Picard, Anne Labonté, Isabelle Aubry, Daniel Auld, Henrik Zetterberg, Kaj Blennow, the PREVENT-AD research group, Michel L. Tremblay, Judes Poirier

Sci Rep. 2024; 14: 14718. Published online 2024 Jun 26. doi: 10.1038/s41598-024-65104-2

PMCID:: PMC11208446

Abstract Article PDF–1.9M

Select item 93873522.

High expression of protein tyrosine phosphatase receptor S (PTPRS) is an independent prognostic marker for cholangiocarcinoma

Muntinee Lertpanprom, Atit Silsirivanit, Patcharaporn Tippayawat, Tanakorn Proungvitaya, Sittiruk Roytrakul, Siriporn Proungvitaya

Front Public Health. 2022; 10: 835914. Published online 2022 Aug 1. doi: 10.3389/fpubh.2022.835914

PMCID:: PMC9387352

Abstract Article PDF–2.8M

Select item 60061543.

PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation

Thomas B. Davis, Mingli Yang, Michael J. Schell, Heiman Wang, Le Ma, W. Jack Pledger, Timothy J. Yeatman

Sci Rep. 2018; 8: 9296. Published online 2018 Jun 18. doi: 10.1038/s41598-018-27584-x

PMCID:: PMC6006154

Abstract Article PDF–6.4M

Select item 32234754.

Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers

Luc G. T. Morris, Barry S. Taylor, Trever G. Bivona, Yongxing Gong, Stephanie Eng, Cameron W. Brennan, Andrew Kaufman, Edward R. Kastenhuber, Victoria E. Banuchi, Bhuvanesh Singh, Adriana Heguy, Agnes Viale, Ingo K. Mellinghoff, Jason Huse, Ian Ganly, Timothy A. Chan

Proc Natl Acad Sci U S A. 2011 Nov 22; 108(47): 19024–19029. Published online 2011 Nov 7. doi: 10.1073/pnas.1111963108

PMCID:: PMC3223475

Abstract Article PDF–1.0M

Select item 30390215.

Identification of PTPσ as an autophagic phosphatase

Katie R. Martin, Yong Xu, Brendan D. Looyenga, Ryan J. Davis, Chia-Lun Wu, Michel L. Tremblay, H. Eric Xu, Jeffrey P. MacKeigan

J Cell Sci. 2011 Mar 1; 124(5): 812–819. Published online 2011 Feb 8. doi: 10.1242/jcs.080341

PMCID:: PMC3039021

Abstract Article

Select item 44583326.

Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy

Karen M. Doody, Stephanie M. Stanford, Cristiano Sacchetti, Mattias N. D. Svensson, Charlotte H. Coles, Nikolaos Mitakidis, William B. Kiosses, Beatrix Bartok, Camille Fos, Esther Cory, Robert L. Sah, Ru Liu-Bryan, David L. Boyle, Heather A. Arnett, Tomas Mustelin, Maripat Corr, Jeffrey D. Esko, Michel L. Tremblay, Gary S. Firestein, A. Radu Aricescu, Nunzio Bottini

Sci Transl Med. Author manuscript; available in PMC 2016 May 20.

Published in final edited form as: Sci Transl Med. 2015 May 20; 7(288): 288ra76. doi: 10.1126/scitranslmed.aaa4616

PMCID:: PMC4458332

Abstract Article PDF–2.6M

Select item 31540937.

Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension

Charlotte H. Coles, Yingjie Shen, Alan P. Tenney, Christian Siebold, Geoffrey C. Sutton, Weixian Lu, John T. Gallagher, E. Yvonne Jones, John G. Flanagan, A. Radu Aricescu

Science. Author manuscript; available in PMC 2012 Apr 22.

Published in final edited form as: Science. 2011 Apr 22; 332(6028): 484–488. Published online 2011 Mar 31. doi: 10.1126/science.1200840

PMCID:: PMC3154093

Abstract Article PDF–1.3M

Select item 42396638.

Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis

Charlotte H. Coles, Nikolaos Mitakidis, Peng Zhang, Jonathan Elegheert, Weixian Lu, Andrew W. Stoker, Terunaga Nakagawa, Ann Marie Craig, E. Yvonne Jones, A. Radu Aricescu

Nat Commun. 2014 Nov 11; 5: 5209. Published online 2014 Nov 11. doi: 10.1038/ncomms6209

PMCID:: PMC4239663

Abstract Article PDF–2.9M

Select item 25860289.

Frameshift mutations in coding repeats of protein tyrosine phosphatase genes in colorectal tumors with microsatellite instability

Sebastian Korff, Stefan M Woerner, Yan P Yuan, Peer Bork, Magnus von Knebel Doeberitz, Johannes Gebert

BMC Cancer. 2008; 8: 329. Published online 2008 Nov 10. doi: 10.1186/1471-2407-8-329

PMCID:: PMC2586028

Abstract Article PDF–500K

Select item 11064010.

The Second Catalytic Domain of Protein Tyrosine Phosphatase δ (PTPδ) Binds to and Inhibits the First Catalytic Domain of PTPς

Megan J. Wallace, Christopher Fladd, Jane Batt, Daniela Rotin

Mol Cell Biol. 1998 May; 18(5): 2608–2616. doi: 10.1128/mcb.18.5.2608

PMCID:: PMC110640

Abstract Article PDF–873K

Select item 4046711.

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

R Pulido, C Serra-Pagès, M Tang, M Streuli

Proc Natl Acad Sci U S A. 1995 Dec 5; 92(25): 11686–11690. doi: 10.1073/pnas.92.25.11686

PMCID:: PMC40467

Summary Page Browse PDF–1.3M

Select item 315685212.

Receptor protein tyrosine phosphatases are novel components of a polycystin complex

Catherine A. Boucher, Heather H. Ward, Ruth L. Case, Katie S. Thurston, Xiaohong Li, Andrew Needham, Elsa Romero, Deborah Hyink, Seema Qamar, Tamara Roitbak, Samantha Powell, Christopher Ward, Patricia D. Wilson, Angela Wandinger-Ness, Richard N. Sandford

Biochim Biophys Acta. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2011 Oct; 1812(10): 1225–1238. Published online 2010 Nov 29. doi: 10.1016/j.bbadis.2010.11.006

PMCID:: PMC3156852

Abstract Article PDF–5.8M

Select item 285955913.

Trans-synaptic Adhesions between Netrin-G Ligand-3 (NGL-3) and Receptor Tyrosine Phosphatases LAR, Protein-tyrosine Phosphatase δ (PTPδ), and PTPσ via Specific Domains Regulate Excitatory Synapse Formation

Seok-Kyu Kwon, Jooyeon Woo, Soo-Young Kim, Hyun Kim, Eunjoon Kim

J Biol Chem. 2010 Apr 30; 285(18): 13966–13978. Published online 2010 Feb 6. doi: 10.1074/jbc.M109.061127

PMCID:: PMC2859559

Abstract Article PDF–5.0M

Select item 454799414.

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells

Anna Bunin, Vanja Sisirak, Hiyaa S. Ghosh, Lucja T. Grajkowska, Z. Esther Hou, Michelle Miron, Cliff Yang, Michele Ceribelli, Noriko Uetani, Laurence Chaperot, Joel Plumas, Wiljan Hendriks, Michel L. Tremblay, Hans Haecker, Louis M. Staudt, Peter H. Green, Govind Bhagat, Boris Reizis

Immunity. Author manuscript; available in PMC 2016 Aug 18.

Published in final edited form as: Immunity. 2015 Aug 18; 43(2): 277–288. Published online 2015 Jul 28. doi: 10.1016/j.immuni.2015.07.009

PMCID:: PMC4547994

Abstract Article PDF–2.1M

Select item 662189015.

Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule

Tomoyuki Yoshida, Tomoko Shiroshima, Sung-Jin Lee, Misato Yasumura, Takeshi Uemura, Xigui Chen, Yoichiro Iwakura, Masayoshi Mishina

J Neurosci. 2012 Feb 22; 32(8): 2588–2600. doi: 10.1523/JNEUROSCI.4637-11.2012

PMCID:: PMC6621890

Abstract Article PDF–5.2M

Select item 359391516.

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases

Yeong Shin Yim, Younghee Kwon, Jungyong Nam, Hong In Yoon, Kangduk Lee, Dong Goo Kim, Eunjoon Kim, Chul Hoon Kim, Jaewon Ko

Proc Natl Acad Sci U S A. 2013 Mar 5; 110(10): 4057–4062. Published online 2013 Jan 23. doi: 10.1073/pnas.1209881110

Correction in:: Proc Natl Acad Sci U S A. 2024 Jun 18; 121(25): e2410441121.

PMCID:: PMC3593915

Abstract Article PDF–1.8M

Select item 433073617.

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission

Ji Seung Ko, Gopal Pramanik, Ji Won Um, Ji Seon Shim, Dongmin Lee, Kee Hun Kim, Gug-Young Chung, Giuseppe Condomitti, Ho Min Kim, Hyun Kim, Joris de Wit, Kang-Sik Park, Katsuhiko Tabuchi, Jaewon Ko

Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6): 1874–1879. Published online 2015 Jan 26. doi: 10.1073/pnas.1410138112

PMCID:: PMC4330736

Abstract Article PDF–1.3M

Select item 957870718.

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia

eLife. 2022; 11: e81398. Published online 2022 Sep 30. doi: 10.7554/eLife.81398

PMCID:: PMC9578707

Abstract Article PDF–3.3M

Select item 317112319.

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

Jason D. Berndt, Atsushi Aoyagi, Peitzu Yang, Jamie N. Anastas, Lan Tang, Randall T. Moon

J Cell Biol. 2011 Sep 5; 194(5): 737–750. doi: 10.1083/jcb.201107021

PMCID:: PMC3171123

Abstract Article PDF–3.3M

Select item 460899720.

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

Nicholas J. Matheson, Jonathan Sumner, Kim Wals, Radu Rapiteanu, Michael P. Weekes, Raphael Vigan, Julia Weinelt, Michael Schindler, Robin Antrobus, Ana S.H. Costa, Christian Frezza, Clary B. Clish, Stuart J.D. Neil, Paul J. Lehner

Cell Host Microbe. 2015 Oct 14; 18(4): 409–423. doi: 10.1016/j.chom.2015.09.003

PMCID:: PMC4608997

Abstract Article PDF–3.8M

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