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Select item 105755871.

A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion

Jie Li, Gregory J. Krause, Qi Gui, Susmita Kaushik, Gergely Rona, Qingyue Zhang, Feng-Xia Liang, Avantika Dhabaria, Carlos Anerillas, Jennifer L. Martindale, Nikita Vasilyev, Manor Askenazi, Beatrix Ueberheide, Evgeny Nudler, Myriam Gorospe, Ana Maria Cuervo, Michele Pagano

Sci Adv. 2023 Oct 13; 9(41): eadh1134. Published online 2023 Oct 13. doi: 10.1126/sciadv.adh1134

PMCID:: PMC10575587

Abstract Article PDF–1.8M

Select item 75215992.

Skp1 Dimerization Conceals its F-box Protein Binding Site

Hyun W. Kim, Alexander Eletsky, Karen J. Gonzalez, Hanke van der Wel, Eva-Maria Strauch, James H. Prestegard, Christopher M. West

Biochemistry. Author manuscript; available in PMC 2021 Apr 21.

Published in final edited form as: Biochemistry. 2020 Apr 21; 59(15): 1527–1536. Published online 2020 Apr 13. doi: 10.1021/acs.biochem.0c00094

PMCID:: PMC7521599

Abstract Article PDF–873K

Select item 38323493.

Pesticides that Inhibit the Ubiquitin-Proteasome System: Effect Measure Modification by Genetic Variation in SKP1 in Parkinson’s Disease

Shannon L. Rhodes, Arthur G. Fitzmaurice, Myles Cockburn, Jeff M. Bronstein, Janet S. Sinsheimer, Beate Ritz

Environ Res. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Environ Res. 2013 Oct; 126: 10.1016/j.envres.2013.08.001. Published online 2013 Aug 27. doi: 10.1016/j.envres.2013.08.001

PMCID:: PMC3832349

Abstract Article PDF–499K

Select item 87449734.

A Comprehensive Assessment of Genetic and Epigenetic Alterations Identifies Frequent Variations Impacting Six Prototypic SCF Complex Members

Rubi Campos Gudiño, Ally C. Farrell, Nicole M. Neudorf, Kirk J. McManus

Int J Mol Sci. 2022 Jan; 23(1): 84. Published online 2021 Dec 22. doi: 10.3390/ijms23010084

PMCID:: PMC8744973

Abstract Article PDF–4.9M

Select item 83538945.

Phytochemical library screening reveals betulinic acid as a novel Skp2‐SCF E3 ligase inhibitor in non–small cell lung cancer

Dan‐Hua He, Yu‐Fei Chen, Yi‐Le Zhou, Shi‐Bing Zhang, Ming Hong, Xianjun Yu, Su‐Fen Wei, Xiang‐Zhen Fan, Si‐Yi Li, Qi Wang, Yongzhi Lu, Yong‐Qiang Liu

Cancer Sci. 2021 Aug; 112(8): 3218–3232. Published online 2021 Jun 28. doi: 10.1111/cas.15005

Correction in:: Cancer Sci. 2024 Jun; 115(6): 2083–2085.

PMCID:: PMC8353894

Abstract Article PDF–3.2M

Select item 53088306.

CacyBP/SIP promotes the proliferation of colon cancer cells

Huihong Zhai, Yongquan Shi, Xiong Chen, Jun Wang, Yuanyuan Lu, Faming Zhang, Zhengxiong Liu, Ting Lei, Daiming Fan

PLoS One. 2017; 12(2): e0169959. Published online 2017 Feb 14. doi: 10.1371/journal.pone.0169959

PMCID:: PMC5308830

Abstract Article PDF–3.5M

Select item 49038917.

Photoactivatable protein labeling by singlet oxygen mediated reactions

Tsz-Leung To, Katalin F. Medzihradszky, Alma L. Burlingame, William F. DeGrado, Hyunil Jo, Xiaokun Shu

Bioorg Med Chem Lett. Author manuscript; available in PMC 2017 Jul 15.

Published in final edited form as: Bioorg Med Chem Lett. 2016 Jul 15; 26(14): 3359–3363. Published online 2016 May 12. doi: 10.1016/j.bmcl.2016.05.034

PMCID:: PMC4903891

Abstract Article PDF–627K

Select item 28055478.

Crystallization and preliminary X-ray characterization of the Skp1–Fbg3 complex

Taichi Kumanomidou, Tomomi Nakagawa, Tsunehiro Mizushima, Atsuo Suzuki, Fuminori Tokunaga, Kazuhiro Iwai, Yukiko Yoshida, Keiji Tanaka, Takashi Yamane

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1; 66(Pt 1): 95–98. Published online 2009 Dec 25. doi: 10.1107/S1744309109050581

PMCID:: PMC2805547

Abstract Article PDF–715K

Select item 27906089.

Molecular Mimicry by an F-Box Effector of Legionella pneumophila Hijacks a Conserved Polyubiquitination Machinery within Macrophages and Protozoa

Christopher T. Price, Souhaila Al-Khodor, Tasneem Al-Quadan, Marina Santic, Fabien Habyarimana, Awdhesh Kalia, Yousef Abu Kwaik

PLoS Pathog. 2009 Dec; 5(12): e1000704. Published online 2009 Dec 24. doi: 10.1371/journal.ppat.1000704

PMCID:: PMC2790608

Abstract Article PDF–4.6M

Select item 278671110.

The Myxoma Virus M-T5 Ankyrin Repeat Host Range Protein Is a Novel Adaptor That Coordinately Links the Cellular Signaling Pathways Mediated by Akt and Skp1 in Virus-Infected Cells

Steven J. Werden, Jerry Lanchbury, Donna Shattuck, Chris Neff, Max Dufford, Grant McFadden

J Virol. 2009 Dec; 83(23): 12068–12083. Published online 2009 Sep 23. doi: 10.1128/JVI.00963-09

PMCID:: PMC2786711

Abstract Article PDF–2.5M

Select item 1069899011.

CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation

Zhenzhou Chen, Yidan Li, Kuan He, Jianguo Yang, Qican Deng, Yajun Chen, Zhongxue Fu

J Exp Clin Cancer Res. 2023; 42: 334. Published online 2023 Dec 6. doi: 10.1186/s13046-023-02915-7

PMCID:: PMC10698990

Abstract Article PDF–14M

Select item 1000609212.

The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei

Ravish Rashpa, Natacha Klages, Domitille Schvartz, Carla Pasquarello, Mathieu Brochet

Nat Commun. 2023; 14: 1312. Published online 2023 Mar 10. doi: 10.1038/s41467-023-36999-8

PMCID:: PMC10006092

Abstract Article PDF–11M

Select item 854853613.

Establishment of high-throughput screening HTRF assay for identification small molecule inhibitors of Skp2-Cks1

Kaizhao Hu, Xiao-Jing Li, Moges Dessale Asmamaw, Xiao-Jing Shi, Hong-Min Liu

Sci Rep. 2021; 11: 21105. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00646-3

Correction in:: Sci Rep. 2021; 11: 22338.

PMCID:: PMC8548536

Abstract Article PDF–4.1M

Select item 821681314.

miR-101-3p Contributes to α-Synuclein Aggregation in Neural Cells through the miR-101-3p/SKP1/PLK2 Pathway

Min Zhang, Wei Liu, Qingan Zhang, Hongfeng Hu

J Healthc Eng. 2021; 2021: 6147434. Published online 2021 Jun 12. doi: 10.1155/2021/6147434

PMCID:: PMC8216813

Abstract Article PDF–2.1M

Select item 811079415.

Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer

Chloe Camille Lepage, Michaela Cora Lynn Palmer, Ally Catherina Farrell, Nicole Marie Neudorf, Zelda Lichtensztejn, Mark William Nachtigal, Kirk James McManus

Br J Cancer. 2021 May 11; 124(10): 1699–1710. Published online 2021 Mar 17. doi: 10.1038/s41416-021-01317-w

PMCID:: PMC8110794

Abstract Article PDF–2.6M

Select item 786344816.

Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression

He Zhu, Hongwei Zhang, Youliang Pei, Zhibin Liao, Furong Liu, Chen Su, Yachong Liu, Renshun Dong, Jia Song, Xuewu Zhang, Yawei Fan, Huifang Liang, Bixiang Zhang, Xiaoping Chen

J Exp Clin Cancer Res. 2021; 40: 57. Published online 2021 Feb 4. doi: 10.1186/s13046-021-01861-6