PMC Links for Gene (Select 6528) - PMC

Romina Celeste Geysels, Carlos Eduardo Bernal Barquero, Mariano Martín, Victoria Peyret, Martina Nocent, Gabriela Sobrero, Liliana Muñoz, Malvina Signorino, Graciela Testa, Ricardo Belisario Castro, Ana María Masini-Repiso, Mirta Beatriz Miras, Juan Pablo Nicola

Front Endocrinol (Lausanne) 2022; 13: 868891. Published online 2022 May 4. doi: 10.3389/fendo.2022.868891

PMCID:: PMC9114739

Article PDF–2.8M

Select item 88619414.

Brief Report: A Novel Sodium/Iodide Symporter Mutation, S356F, Causing Congenital Hypothyroidism

Harsh Durgia, Adeline K. Nicholas, Erik Schoenmakers, Jennifer A. Dickens, Dhanapathi Halanaik, Jayaprakash Sahoo, Sadishkumar Kamalanathan, Nadia Schoenmakers

Thyroid. February 2022; 32(2): 215–218. Published online 2022 Feb 10. doi: 10.1089/thy.2021.0478

PMCID:: PMC8861941

Article PDF–276K

Select item 83775155.

The Iodide Transport Defect-Causing Y348D Mutation in the Na⁺/I⁻ Symporter Renders the Protein Intrinsically Inactive and Impairs Its Targeting to the Plasma Membrane

Andrea Reyna-Neyra, Lara Jung, Mayukh Chakrabarti, Mikel X. Suárez, L. Mario Amzel, Nancy Carrasco

Thyroid. August 2021; 31(8): 1272–1281. Published online 2021 Aug 3. doi: 10.1089/thy.2020.0931

PMCID:: PMC8377515

Article PDF–1.2M

Select item 77229196.

Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma

Hassan Rakhsh-Khorshid, Hilda Samimi, Shukoofeh Torabi, Sayed Mahmoud Sajjadi-Jazi, Hamed Samadi, Fatemeh Ghafouri, Yazdan Asgari, Vahid Haghpanah

Sci Rep. 2020; 10: 21440. Published online 2020 Dec 8. doi: 10.1038/s41598-020-78574-x

PMCID:: PMC7722919

Article PDF–1.5M

Select item 70102207.

Iodine-131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma

Ana Filipa Brito, Ana Margarida Abrantes, Ricardo Teixo, Ana Salomé Pires, Ana Cláudia Ribeiro, Rafael Fernandes Ferreira, Alexandra Mascarenhas, Tiago Puga, Mafalda Laranjo, Francisco Caramelo, Ilka Boin, Douglas M. Jefferson, Cristina Gonçalves, Ricardo Martins, Inês Tavares, Ilda Patrícia Ribeiro, Ana Bela Sarmento-Ribeiro, Isabel Marques Ferreira, Doroteia Souza, José Guilherme Tralhão, Maria Filomena Botelho

Int J Oncol. 2020 Mar; 56(3): 709–727. Published online 2020 Jan 10. doi: 10.3892/ijo.2020.4957

PMCID:: PMC7010220

Article PDF–1.4M

Select item 69365618.

A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na⁺/I⁻ Symporter

Mariano Martín, Carlos Pablo Modenutti, Victoria Peyret, Romina Celeste Geysels, Elisabeth Darrouzet, Thierry Pourcher, Ana María Masini-Repiso, Marcelo Adrián Martí, Nancy Carrasco, Juan Pablo Nicola

Endocrinology. 2019 Jan; 160(1): 156–168. Published online 2018 Nov 28. doi: 10.1210/en.2018-00603

PMCID:: PMC6936561

Article

Select item 67970799.

Dimerization of the Sodium/Iodide Symporter

Rebecca J. Thompson, Alice Fletcher, Katie Brookes, Hannah Nieto, Mohammed M. Alshahrani, Jonathan W. Mueller, Nicholas H.F. Fine, David J. Hodson, Kristien Boelaert, Martin L. Read, Vicki E. Smith, Christopher J. McCabe

Thyroid. 2019 Oct 1; 29(10): 1485–1498. Published online 2019 Oct 15. doi: 10.1089/thy.2019.0034

PMCID:: PMC6797079

Article PDF–1.6M

Select item 534238310.

Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy

Corinne Renier, John Do, Andrea Reyna-Neyra, Deshka Foster, Abhijit De, Hannes Vogel, Stefanie S. Jeffrey, Victor Tse, Nancy Carrasco, Irene Wapnir

Oncotarget. 2016 Aug 23; 7(34): 54811–54824. Published online 2016 Jun 23. doi: 10.18632/oncotarget.10238

PMCID:: PMC5342383

Article PDF–6.6M

Select item 534238211.

Hypoxia-targeted ¹³¹I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery

Andrea M. Müller, Kathrin A. Schmohl, Kerstin Knoop, Christina Schug, Sarah Urnauer, Anna Hagenhoff, Dirk-André Clevert, Michael Ingrisch, Hanno Niess, Janette Carlsen, Christian Zach, Ernst Wagner, Peter Bartenstein, Peter J. Nelson, Christine Spitzweg

Oncotarget. 2016 Aug 23; 7(34): 54795–54810. Published online 2016 Jul 21. doi: 10.18632/oncotarget.10758

PMCID:: PMC5342382

Article PDF–13M

Select item 502746212.

Na⁺ coordination at the Na2 site of the Na⁺/I⁻ symporter

Giuseppe Ferrandino, Juan Pablo Nicola, Yuly E. Sánchez, Ignacia Echeverria, Yunlong Liu, L. Mario Amzel, Nancy Carrasco

Proc Natl Acad Sci U S A. 2016 Sep 13; 113(37): E5379–E5388. Published online 2016 Aug 25. doi: 10.1073/pnas.1607231113

PMCID:: PMC5027462

Article PDF–1.6M

Select item 401936213.

Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer

Salvatore Micali, Stefania Bulotta, Cinzia Puppin, Angelo Territo, Michele Navarra, Giampaolo Bianchi, Giuseppe Damante, Sebastiano Filetti, Diego Russo

BMC Cancer. 2014; 14: 303. Published online 2014 Apr 30. doi: 10.1186/1471-2407-14-303

PMCID:: PMC4019362

Article PDF–468K

Select item 383752114.

MEK Inhibition Leads To Lysosome-Mediated Na⁺/I^- Symporter Protein Degradation In Human Breast Cancer Cells

Zhaoxia Zhang, Sasha Beyer, Sissy M Jhiang

Endocr Relat Cancer. Author manuscript; available in PMC 2013 Nov 22.

Published in final edited form as: Endocr Relat Cancer. 2013 Apr; 20(2): 10.1530/ERC-12-0342. Published online 2013 Mar 22. doi: 10.1530/ERC-12-0342

PMCID:: PMC3837521

Article PDF–1.1M

Select item 375251215.

Modulation of Sodium/Iodide Symporter Expression in the Salivary Gland

Krista M.D. La Perle, Dong Chul Kim, Nathan C. Hall, Adam Bobbey, Daniel H. Shen, Rebecca S. Nagy, Paul E. Wakely, Jr., Amy Lehman, David Jarjoura, Sissy M. Jhiang

Thyroid. 2013 Aug; 23(8): 1029–1036. doi: 10.1089/thy.2012.0571

PMCID:: PMC3752512

Article PDF–1.0M

Select item 373024216.

The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na⁺/I⁻ symporter

Viktoriya Paroder, Juan P. Nicola, Christopher S. Ginter, Nancy Carrasco

J Cell Sci. 2013 Aug 1; 126(15): 3305–3313. doi: 10.1242/jcs.120246

PMCID:: PMC3730242

Article

Select item 371458317.

Asn441 plays a key role in folding and function of the Na⁺/I⁻ symporter (NIS)

Wenjing Li, Juan Pablo Nicola, L. Mario Amzel, Nancy Carrasco

FASEB J. 2013 Aug; 27(8): 3229–3238. doi: 10.1096/fj.13-229138

PMCID:: PMC3714583

Article

Select item 351748418.

Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine

Brian Hutzen, Christopher R Pierson, Stephen J Russell, Evanthia Galanis, Corey Raffel, Adam W Studebaker

BMC Cancer. 2012; 12: 508. Published online 2012 Nov 7. doi: 10.1186/1471-2407-12-508

PMCID:: PMC3517484

Article PDF–1.5M

Select item 318236919.

Image-guided, Tumor Stroma-targeted ¹³¹I Therapy of Hepatocellular Cancer After Systemic Mesenchymal Stem Cell-mediated NIS Gene Delivery

Kerstin Knoop, Marie Kolokythas, Kathrin Klutz, Michael J. Willhauck, Nathalie Wunderlich, Dan Draganovici, Christian Zach, Franz-Josef Gildehaus, Guido Böning, Burkhard Göke, Ernst Wagner, Peter J. Nelson, Christine Spitzweg

Mol Ther. 2011 Sep; 19(9): 1704–1713. Published online 2011 May 17. doi: 10.1038/mt.2011.93

PMCID:: PMC3182369

Article PDF–712K

Select item 300292020.

Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity

Chia-Cheng Li, Tin-Yun Ho, Chia-Hung Kao, Shih-Lu Wu, Ji-An Liang, Chien-Yun Hsiang

J Biomed Sci. 2010; 17(1): 89. Published online 2010 Nov 23. doi: 10.1186/1423-0127-17-89

PMCID:: PMC3002920

Article PDF–1.0M

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