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Select item 85838161.

Amino Acids 785, 787 of the Na⁺/H⁺ Exchanger Cytoplasmic Tail Modulate Protein Activity and Tail Conformation

Xiuju Li, Tommy Tu, Sicheng Quan, Francisco J. Quintero, Richard Fahlman, Larry Fliegel

Int J Mol Sci. 2021 Nov; 22(21): 11349. Published online 2021 Oct 21. doi: 10.3390/ijms222111349

PMCID:: PMC8583816

Abstract Article PDF–2.6M

Select item 85090382.

Inhibition of NHE-1 Increases Smoke-Induced Proliferative Activity of Barrett’s Esophageal Cell Line

Eszter Becskeházi, Marietta Margaréta Korsós, Eleonóra Gál, László Tiszlavicz, Zsófia Hoyk, Mária A. Deli, Zoltán Márton Köhler, Anikó Keller-Pintér, Attila Horváth, Kata Csekő, Zsuzsanna Helyes, Péter Hegyi, Viktória Venglovecz

Int J Mol Sci. 2021 Oct; 22(19): 10581. Published online 2021 Sep 30. doi: 10.3390/ijms221910581

PMCID:: PMC8509038

Abstract Article PDF–2.3M

Select item 83217913.

Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells

Sagar S. Manoli, Kyle Kisor, Bradley A. Webb, Diane L. Barber

Am J Physiol Cell Physiol. 2021 Jul 1; 321(1): C147–C157. Published online 2021 May 26. doi: 10.1152/ajpcell.00001.2021

PMCID:: PMC8321791

Abstract Article

Select item 80096644.

Dynamic Na⁺/H⁺ exchanger 1 (NHE1) – calmodulin complexes of varying stoichiometry and structure regulate Ca²⁺-dependent NHE1 activation

Lise M Sjøgaard-Frich, Andreas Prestel, Emilie S Pedersen, Marc Severin, Kristian Kølby Kristensen, Johan G Olsen, Birthe B Kragelund, Stine Falsig Pedersen

eLife. 2021; 10: e60889. Published online 2021 Mar 3. doi: 10.7554/eLife.60889

PMCID:: PMC8009664

Abstract Article PDF–5.7M

Select item 77133845.

The intracellular lipid-binding domain of human Na⁺/H⁺ exchanger 1 forms a lipid-protein co-structure essential for activity

Ruth Hendus-Altenburger, Jens Vogensen, Emilie Skotte Pedersen, Alessandra Luchini, Raul Araya-Secchi, Anne H. Bendsoe, Nanditha Shyam Prasad, Andreas Prestel, Marité Cardenas, Elena Pedraz-Cuesta, Lise Arleth, Stine F. Pedersen, Birthe B. Kragelund

Commun Biol. 2020; 3: 731. Published online 2020 Dec 3. doi: 10.1038/s42003-020-01455-6

PMCID:: PMC7713384

Abstract Article PDF–4.5M

Select item 73766486.

Roles of hsa-miR-12462 and SLC9A1 in acute myeloid leukemia

Yan Jia, Wei Liu, Hui-En Zhan, Xiao-Ping Yi, Hui Liang, Qi-Li Zheng, Xin-Ya Jiang, Hai-Yan Zhou, Liang Zhao, Xie-Lan Zhao, Hui Zeng

J Hematol Oncol. 2020; 13: 101. Published online 2020 Jul 23. doi: 10.1186/s13045-020-00935-w

PMCID:: PMC7376648

Abstract Article PDF–3.0M

Select item 66960907.

The Role of Sodium Hydrogen Exchanger 1 in Dysregulation of Proton Dynamics and Reprogramming of Cancer Metabolism as a Sequela

Rosa Angela Cardone, Khalid Omer Alfarouk, Robert L. Elliott, Saad Saeed Alqahtani, Samrein B. M. Ahmed, Ahmed N. Aljarbou, Maria Raffaella Greco, Stefania Cannone, Stephan Joel Reshkin

Int J Mol Sci. 2019 Aug; 20(15): 3694. Published online 2019 Jul 28. doi: 10.3390/ijms20153694

PMCID:: PMC6696090

Abstract Article PDF–511K

Select item 66778188.

Molecular basis for the binding and selective dephosphorylation of Na⁺/H⁺ exchanger 1 by calcineurin

Ruth Hendus-Altenburger, Xinru Wang, Lise M. Sjøgaard-Frich, Elena Pedraz-Cuesta, Sarah R. Sheftic, Anne H. Bendsøe, Rebecca Page, Birthe B. Kragelund, Stine F. Pedersen, Wolfgang Peti

Nat Commun. 2019; 10: 3489. Published online 2019 Aug 2. doi: 10.1038/s41467-019-11391-7

PMCID:: PMC6677818

Abstract Article PDF–2.7M

Select item 65389989.

Sodium-Hydrogen Exchanger Isoform-1 Inhibition: A Promising Pharmacological Intervention for Resuscitation from Cardiac Arrest

Raúl J. Gazmuri, Jeejabai Radhakrishnan, Iyad M. Ayoub

Molecules. 2019 May; 24(9): 1765. Published online 2019 May 7. doi: 10.3390/molecules24091765

PMCID:: PMC6538998

Abstract Article PDF–2.7M

Select item 637486010.

Upregulated Na⁺/H⁺-Exchange Protects Human Colon Cancer Tissue against Intracellular Acidification

Ninna C. S. Voss, Henrik Kold-Petersen, Mikkel B. Henningsen, Casper Homilius, Ebbe Boedtkjer

Biomed Res Int. 2019; 2019: 3702783. Published online 2019 Jan 29. doi: 10.1155/2019/3702783

PMCID:: PMC6374860

Abstract Article PDF–814K

Select item 619230911.

Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas

Xiudong Guan, Lanxin Luo, Gulnaz Begum, Gary Kohanbash, Qingkun Song, Aparna Rao, Nduka Amankulor, Baoshan Sun, Dandan Sun, Wang Jia

J Exp Clin Cancer Res. 2018; 37: 255. Published online 2018 Oct 17. doi: 10.1186/s13046-018-0923-z

PMCID:: PMC6192309

Abstract Article PDF–6.7M

Select item 544504212.

Sodium-Hydrogen-Exchanger expression in human sperm and its relationship with semen parameters

Zhe Zhang, Yuzhuo Yang, Han Wu, Hongliang Zhang, Haitao Zhang, Jiaming Mao, Defeng Liu, Lianming Zhao, Haocheng Lin, Wenhao Tang, Kai Hong, Hui Jiang

J Assist Reprod Genet. 2017 Jun; 34(6): 795–801. Published online 2017 Apr 21. doi: 10.1007/s10815-017-0898-2

PMCID:: PMC5445042

Abstract Article PDF–692K

Select item 542657613.

Prolactin Signaling Stimulates Invasion via Na⁺/H⁺ Exchanger NHE1 in T47D Human Breast Cancer Cells

Elena Pedraz-Cuesta, Jacob Fredsted, Helene H. Jensen, Annika Bornebusch, Lene N. Nejsum, Birthe B. Kragelund, Stine F. Pedersen

Mol Endocrinol. 2016 Jul; 30(7): 693–708. Published online 2016 May 13. doi: 10.1210/me.2015-1299

PMCID:: PMC5426576

Abstract Article

Select item 535679314.

Na⁺/H⁺ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma

Yosuke Ariyoshi, Atsushi Shiozaki, Daisuke Ichikawa, Hiroki Shimizu, Toshiyuki Kosuga, Hirotaka Konishi, Shuhei Komatsu, Hitoshi Fujiwara, Kazuma Okamoto, Mitsuo Kishimoto, Yoshinori Marunaka, Eigo Otsuji

Oncotarget. 2017 Jan 10; 8(2): 2209–2223. Published online 2016 Nov 26. doi: 10.18632/oncotarget.13645