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Select item 71830361.

Efficient SNP editing in haploid human pluripotent stem cells

Lauren Zakarin Safier, Michael V Zuccaro, Dietrich Egli

J Assist Reprod Genet. 2020 Apr; 37(4): 735–745. Published online 2020 Mar 11. doi: 10.1007/s10815-020-01723-8

PMCID:: PMC7183036

Abstract Article PDF–876K

Select item 71359722.

S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells

Alexander L. Ticho, Pooja Malhotra, Christopher R. Manzella, Pradeep K. Dudeja, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai

J Biol Chem. 2020 Apr 3; 295(14): 4488–4497. Published online 2020 Feb 18. doi: 10.1074/jbc.RA119.011032

PMCID:: PMC7135972

Abstract Article PDF–1.0M

Select item 57802533.

Human Bile Acid Transporter ASBT (SLC10A2) Forms Functional Non-Covalent Homodimers and Higher Order Oligomers

Paresh P. Chothe, Lindsay C Czuba, Robyn H. Moore, Peter W. Swaan

Biochim Biophys Acta. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Biochim Biophys Acta. 2018 Mar; 1860(3): 645–653. Published online 2017 Dec 1. doi: 10.1016/j.bbamem.2017.11.016

PMCID:: PMC5780253

Abstract Article PDF–1.2M

Select item 48800144.

Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts

Fadi Annaba, Zaheer Sarwar, Pradeep Kumar, Seema Saksena, Jerrold R. Turner, Pradeep K. Dudeja, Ravinder K. Gill, Waddah A. Alrefai

Am J Physiol Gastrointest Liver Physiol. Author manuscript; available in PMC 2016 May 25.

Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2008 Feb; 294(2): G489–G497. Published online 2007 Dec 6. doi: 10.1152/ajpgi.00237.2007

PMCID:: PMC4880014

Abstract Article PDF–871K

Select item 44697485.

N-glycosylation is essential for ileal ASBT function and protection against proteases

Saminathan Muthusamy, Pooja Malhotra, Mobashir Hosameddin, Amish K. Dudeja, Sujata Borthakur, Seema Saksena, Ravinder K. Gill, Pradeep K. Dudeja, Waddah A. Alrefai

Am J Physiol Cell Physiol. 2015 Jun 15; 308(12): C964–C971. Published online 2015 Apr 8. doi: 10.1152/ajpcell.00023.2015

PMCID:: PMC4469748

Abstract Article

Select item 38208746.

Transmembrane Domain II of the Human Bile Acid Transporter SLC10A2 Coordinates Sodium Translocation

Hairat Sabit, Sairam S. Mallajosyula, Alexander D. MacKerell, Jr., Peter W. Swaan

J Biol Chem. 2013 Nov 8; 288(45): 32394–32404. Published online 2013 Sep 17. doi: 10.1074/jbc.M113.518555

PMCID:: PMC3820874

Abstract Article PDF–4.9M

Select item 33620997.

Enteropathogenic Escherichia coli inhibits ileal sodium-dependent bile acid transporter ASBT

Fadi Annaba, Zaheer Sarwar, Ravinder K. Gill, Amit Ghosh, Seema Saksena, Alip Borthakur, Gail A. Hecht, Pradeep K. Dudeja, Waddah A. Alrefai

Am J Physiol Gastrointest Liver Physiol. 2012 May 15; 302(10): G1216–G1222. doi: 10.1152/ajpgi.00017.2012

PMCID:: PMC3362099

Abstract Article

Select item 32610988.

Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts

Anke Tönjes, Henning Wittenburg, Jan Halbritter, Olga Renner, Simone Harsch, Eduard F Stange, Frank Lammert, Michael Stumvoll, Peter Kovacs

BMC Med Genet. 2011; 12: 149. Published online 2011 Nov 17. doi: 10.1186/1471-2350-12-149

PMCID:: PMC3261098

Abstract Article PDF–237K

Select item 31706689.

Functional Characterization of Genetic Variants in the Apical Sodium-Dependent Bile Acid Transporter (ASBT; SLC10A2)

Richard H. Ho, Brenda F. Leake, Brad L. Urquhart, Jamie C. Gregor, Paul A. Dawson, Richard B. Kim

J Gastroenterol Hepatol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: J Gastroenterol Hepatol. 2011 Dec; 26(12): 1740–1748. doi: 10.1111/j.1440-1746.2011.06805.x

PMCID:: PMC3170668

Abstract Article PDF–1.3M

Select item 314932610.

Transmembrane Helix 1 Contributes to Substrate Translocation and Protein Stability of Bile Acid Transporter SLC10A2

Tatiana Claro da Silva, Naissan Hussainzada, Chandra M. Khantwal, James E. Polli, Peter W. Swaan

J Biol Chem. 2011 Aug 5; 286(31): 27322–27332. Published online 2011 Jun 6. doi: 10.1074/jbc.M110.217802

PMCID:: PMC3149326

Abstract Article PDF–3.4M

Select item 291228811.

Synthesis and In Vitro Evaluation of Potential Sustained Release Prodrugs via Targeting ASBT

Xiaowan Zheng, James E. Polli

Int J Pharm. Author manuscript; available in PMC 2011 Aug 30.

Published in final edited form as: Int J Pharm. 2010 Aug 30; 396(1-2): 111–118. Published online 2010 Jul 1. doi: 10.1016/j.ijpharm.2010.06.039

PMCID:: PMC2912288

Abstract Article PDF–906K

Select item 287672112.

Cytosolic Half of Helix III Forms Substrate Exit Route during Permeation Events of the Sodium/Bile Acid Cotransporter ASBT

Naissan Hussainzada, Tatiana Claro Da Silva, Peter W. Swaan

Biochemistry. Author manuscript; available in PMC 2010 Sep 15.

Published in final edited form as: Biochemistry. 2009 Sep 15; 48(36): 8528–8539. doi: 10.1021/bi900616w

PMCID:: PMC2876721

Abstract Article PDF–2.1M

Select item 283851713.

Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT

Fadi Annaba, Pradeep Kumar, Amish K. Dudeja, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai

Am J Physiol Gastrointest Liver Physiol. 2010 Mar; 298(3): G467–G473. Published online 2010 Jan 7. doi: 10.1152/ajpgi.00360.2009

PMCID:: PMC2838517

Abstract Article

Select item 279613214.

Apical Sodium Dependent Bile Acid Transporter (ASBT, SLC10A2): A Potential Prodrug Target

Anand Balakrishnan, James E. Polli

Mol Pharm. Author manuscript; available in PMC 2009 Dec 18.

Published in final edited form as: Mol Pharm. 2006 May–Jun; 3(3): 223–230. doi: 10.1021/mp060022d

PMCID:: PMC2796132

Abstract Article PDF–490K

Select item 275791115.

A Variant of the SLC10A2 Gene Encoding the Apical Sodium-Dependent Bile Acid Transporter Is a Risk Factor for Gallstone Disease

Olga Renner, Simone Harsch, Elke Schaeffeler, Stefan Winter, Matthias Schwab, Marcin Krawczyk, Jonas Rosendahl, Henning Wittenburg, Frank Lammert, Eduard F. Stange

PLoS One. 2009; 4(10): e7321. Published online 2009 Oct 13. doi: 10.1371/journal.pone.0007321

PMCID:: PMC2757911

Abstract Article PDF–112K

Select item 252628316.

Influence of Charge and Steric Bulk in C-24 Region on the Interaction of Bile Acids with Human Apical Sodium Dependent Bile Acid Transporter (hASBT)

Anand Balakrishnan, Stephen A. Wring, Andrew Coop, James E. Polli

Mol Pharm. Author manuscript; available in PMC 2008 Aug 28.

Published in final edited form as: Mol Pharm. 2006; 3(3): 282–292. doi: 10.1021/mp0600135

PMCID:: PMC2526283

Abstract Article PDF–1.4M

Select item 252580517.

Membrane Topology Of Human ASBT (SLC10A2) Determined By Dual Label Epitope Insertion Scanning Mutagenesis. New Evidence For Seven Transmembrane Domains

Antara Banerjee, Peter W. Swaan

Biochemistry. Author manuscript; available in PMC 2008 Aug 27.

Published in final edited form as: Biochemistry. 2006 Jan 24; 45(3): 943–953. doi: 10.1021/bi052202j

PMCID:: PMC2525805

Abstract Article PDF–1.9M

Select item 249285218.

Effects of common haplotypes of the ileal sodium dependent bile acid transporter gene on the development of sporadic and familial colorectal cancer: A case control study

Frank Grünhage, Matthias Jungck, Christoph Lamberti, Hildegard Keppeler, Ursula Becker, Hildegard Schulte-Witte, Dominik Plassmann, Nicolaus Friedrichs, Reinhard Buettner, Stefan Aretz, Tilman Sauerbruch, Frank Lammert

BMC Med Genet. 2008; 9: 70. Published online 2008 Jul 21. doi: 10.1186/1471-2350-9-70