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Items: 1 to 20 of 76

1.
Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent signaling pathway
Yulong Lan, Jiacheng Lou, Jiliang Hu, Zhikuan Yu, Wen Lyu, Bo Zhang
Cancer Biol Med. 2020 Feb 15; 17(1): 112–131. Published online 2020 Feb 15. doi: 10.20892/j.issn.2095-3941.2019.0164
PMCID:
PMC7142844
AbstractArticlePDF–2.2M
2.
Structure of a Key Intermediate of the SMN Complex Reveals Gemin2’s Crucial Function in snRNP Assembly
Rundong Zhang, Byung Ran So, Pilong Li, Jeongsik Yong, Tina Glisovic, Lili Wan, Gideon Dreyfuss
Cell. Author manuscript; available in PMC 2012 Feb 5.
Published in final edited form as: Cell. 2011 Aug 5; 146(3): 384–395. doi: 10.1016/j.cell.2011.06.043
PMCID:
PMC3160754
AbstractArticlePDF–6.6M
3.
Sm protein–Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure
Henning Urlaub, Veronica A. Raker, Susanne Kostka, Reinhard Lührmann
EMBO J. 2001 Jan 15; 20(1-2): 187–196. doi: 10.1093/emboj/20.1.187
PMCID:
PMC140196
AbstractArticlePDF–735K
4.
Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly
Hongfei Yi, Li Mu, Congcong Shen, Xi Kong, Yingzhi Wang, Yan Hou, Rundong Zhang
Nucleic Acids Res. 2020 Jan 24; 48(2): 895–911. Published online 2019 Dec 4. doi: 10.1093/nar/gkz1135
PMCID:
PMC6954390
AbstractArticlePDF–5.2M
5.
An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands
Sébastien Campagne, Tebbe de Vries, Florian Malard, Pavel Afanasyev, Georg Dorn, Emil Dedic, Joachim Kohlbrecher, Daniel Boehringer, Antoine Cléry, Frédéric H-T Allain
Nucleic Acids Res. 2021 Jun 21; 49(11): e63. Published online 2021 Mar 2. doi: 10.1093/nar/gkab135
PMCID:
PMC8216277
AbstractArticlePDF–3.5M
6.
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1
Max Felle, Saskia Joppien, Attila Németh, Sarah Diermeier, Verena Thalhammer, Thomas Dobner, Elisabeth Kremmer, Roland Kappler, Gernot Längst
Nucleic Acids Res. 2011 Oct; 39(19): 8355–8365. Published online 2011 Jul 9. doi: 10.1093/nar/gkr528
PMCID:
PMC3201865
AbstractArticlePDF–4.6M
7.
Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems
Bernard Charroux, Livio Pellizzoni, Robert A. Perkinson, Andrej Shevchenko, Matthias Mann, Gideon Dreyfuss
J Cell Biol. 1999 Dec 13; 147(6): 1181–1194. doi: 10.1083/jcb.147.6.1181
PMCID:
PMC2168095
AbstractArticlePDF–535K
8.
Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis
Adelaine K. W. Leung, Kiyoshi Nagai, Jade Li
Nature. Author manuscript; available in PMC 2011 Nov 26.
Published in final edited form as: Nature. 2011 May 26; 473(7348): 536–539. Published online 2011 Apr 24. doi: 10.1038/nature09956
PMCID:
PMC3103711
AbstractArticlePDF–2.1M
9.
Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein
Ramesh S. Pillai, Cindy L. Will, Reinhard Lührmann, Daniel Schümperli, Berndt Müller
EMBO J. 2001 Oct 1; 20(19): 5470–5479. doi: 10.1093/emboj/20.19.5470
PMCID:
PMC125645
AbstractArticlePDF–288K
10.
Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition
Yasushi Kondo, Chris Oubridge, Anne-Marie M van Roon, Kiyoshi Nagai
eLife. 2015; 4: e04986. Published online 2015 Jan 2. doi: 10.7554/eLife.04986
PMCID:
PMC4383343
AbstractArticlePDF–2.8M
11.
Gemin4: A Novel Component of the Smn Complex That Is Found in Both Gems and Nucleoli
Bernard Charroux, Livio Pellizzoni, Robert A. Perkinson, Jeongsik Yong, Andrej Shevchenko, Matthias Mann, Gideon Dreyfuss
J Cell Biol. 2000 Mar 20; 148(6): 1177–1186. doi: 10.1083/jcb.148.6.1177
PMCID:
PMC2174312
AbstractArticlePDF–319K
12.
Functional organization of the Sm core in the crystal structure of human U1 snRNP
Gert Weber, Simon Trowitzsch, Berthold Kastner, Reinhard Lührmann, Markus C Wahl
EMBO J. 2010 Dec 15; 29(24): 4172–4184. Published online 2010 Nov 26. doi: 10.1038/emboj.2010.295
PMCID:
PMC3018796
AbstractArticlePDF–2.1M
13.
Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly
Fenghua Yang, Tong Bian, Xiechao Zhan, Zhe Chen, Zhihan Xing, Nicolas A. Larsen, Xiaofeng Zhang, Yigong Shi
Nat Commun. 2023; 14: 897. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36489-x
PMCID:
PMC9935549
AbstractArticlePDF–4.2M
14.
Structural and Functional Modularity of the U2 snRNP in pre-mRNA Splicing
Clarisse van der Feltz, Aaron A. Hoskins
Crit Rev Biochem Mol Biol. Author manuscript; available in PMC 2020 Nov 20.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2019 Oct; 54(5): 443–465. Published online 2019 Nov 20. doi: 10.1080/10409238.2019.1691497
PMCID:
PMC6934263
AbstractArticlePDF–3.1M
15.
PEA15 Regulates the DNA Damage-Induced Cell Cycle Checkpoint and Oncogene-Directed Transformation
Arvindhan Nagarajan, Shaillay Kumar Dogra, Alex Y. Liu, Michael R. Green, Narendra Wajapeyee
Mol Cell Biol. 2014 Jun; 34(12): 2264–2282. doi: 10.1128/MCB.01542-13
PMCID:
PMC4054289
AbstractArticlePDF–6.2M
16.
Mechanism of 5′ splice site transfer for human spliceosome activation
Clément Charenton, Max E. Wilkinson, Kiyoshi Nagai
Science. Author manuscript; available in PMC 2019 Oct 26.
Published in final edited form as: Science. 2019 Apr 26; 364(6438): 362–367. Published online 2019 Apr 11. doi: 10.1126/science.aax3289
PMCID:
PMC6525098
AbstractArticlePDF–2.5M
17.
Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly
Zhe Chen, Bin Gui, Yu Zhang, Guojia Xie, Wanjin Li, Shumeng Liu, Bosen Xu, Chongyang Wu, Lin He, Jianguo Yang, Xia Yi, Xiaohan Yang, Luyang Sun, Jing Liang, Yongfeng Shang
J Biol Chem. 2017 Nov 3; 292(44): 18113–18128. Published online 2017 Sep 6. doi: 10.1074/jbc.M117.797357
PMCID:
PMC5672036
AbstractArticlePDF–2.9M
18.
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein
Cindy L. Will, Henning Urlaub, Tilmann Achsel, Marc Gentzel, Matthias Wilm, Reinhard Lührmann
EMBO J. 2002 Sep 16; 21(18): 4978–4988. doi: 10.1093/emboj/cdf480
PMCID:
PMC126279
AbstractArticlePDF–228K
19.
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome
CINDY L. WILL, CLAUDIA SCHNEIDER, MARKUS HOSSBACH, HENNING URLAUB, REINHARD RAUHUT, SAYDA ELBASHIR, THOMAS TUSCHL, REINHARD LÜHRMANN
RNA. 2004 Jun; 10(6): 929–941. doi: 10.1261/rna.7320604
PMCID:
PMC1370585
AbstractArticlePDF–396K
20.
Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6
Irina Evsyukova, Shelton S. Bradrick, Simon G. Gregory, Mariano A. Garcia-Blanco
RNA. 2013 Jan; 19(1): 103–115. doi: 10.1261/rna.035410.112
PMCID:
PMC3527722
AbstractArticlePDF–866K

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